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1.
Proc Biol Sci ; 290(1991): 20222204, 2023 01 25.
Article in English | MEDLINE | ID: mdl-36651047

ABSTRACT

Helminth transmission and morbidity are dependent on the number of mature parasites within a host; however, observing adult worms is impossible for many natural infections. An outstanding challenge is therefore relating routine diagnostics, such as faecal egg counts, to the underlying worm burden. This relationship is complicated by density-dependent fecundity (egg output per worm reduces due to crowding at high burdens) and the skewed distribution of parasites (majority of helminths aggregated in a small fraction of hosts). We address these questions for the carcinogenic liver fluke Opisthorchis viverrini, which infects approximately 10 million people across Southeast Asia, by analysing five epidemiological surveys (n = 641) where adult flukes were recovered. Using a mechanistic model, we show that parasite fecundity varies between populations, with surveys from Thailand and Laos demonstrating distinct patterns of egg output and density-dependence. As the probability of observing faecal eggs increases with the number of mature parasites within a host, we quantify diagnostic sensitivity as a function of the worm burden and find that greater than 50% of cases are misdiagnosed as false negative in communities close to elimination. Finally, we demonstrate that the relationship between observed prevalence from routine diagnostics and true prevalence is nonlinear and strongly influenced by parasite aggregation.


Subject(s)
Helminths , Parasites , Trematoda , Animals , Fertility , Parasite Egg Count , Feces/parasitology
2.
Soc Psychiatry Psychiatr Epidemiol ; 57(10): 2131-2145, 2022 Oct.
Article in English | MEDLINE | ID: mdl-34398264

ABSTRACT

We present a cultural adaptation of the Growth and Empowerment Measure (GEM) from the Kanien'kehá:ka people of Quebec (Canada). Our aim was to develop a culturally competent and safe tool to assess and promote well-being among this population. We followed a qualitative, collaborative, and participatory method that sought to benefit Indigenous participants and communities, while honouring their culture and philosophies. Twelve adults from health and community services of Kahnawà:ke participated in total five focus group meetings. We carried out a thematic analysis of the data collected through an advisory group that led a revision of the cultural and conceptual relevance of the tool and its content. The group integrated socio-culturally relevant elements and restructured the tool so that it reflected local well-being factors and showed its versatility of being an assessment tool and therapeutic support. A narrative and empowerement-driven approach, culturally based intervention, cultural safety and flexibility when using the instrument were considered successful strategies to improve wellness. This project provides valuable information about the perspectives of local Indigenous communities regarding mental health and factors of empowerment. Mutual understanding and integration of psychological and traditional knowledge can create a beneficial program to improve emotional, mental, spiritual, and physical well-being for the local population. It remains to be tested whether the Kanien'kehá:ka Growth and Empowerment Measure (K-GEM) is clinically useful in psychological and psychiatric intervention, and social and community services.


Subject(s)
Diabetes Mellitus, Type 2 , Mental Health , Adult , Canada , Humans , Quebec
3.
Soc Psychiatry Psychiatr Epidemiol ; 56(10): 1891-1902, 2021 Oct.
Article in English | MEDLINE | ID: mdl-33683413

ABSTRACT

PURPOSE: We present a study on selection of a psychometric scale to be clinically used among Indigenous people with depression. Our aim was to select a psychometric tool for cultural adaptation with Mohawk and Inuit in Quebec. METHODS: We selected three depression scales and three protective factor scales based on: strong validity for psychometric properties, evidence for good psychometric qualities across translations, avoidance of cognitively complex sentences, brevity, and clarity. We submitted the scales for consultation, and followed qualitative participatory methods with Mohawks of Kahnawake and Inuit from Nunavik living in an urban environment. We collected data through ten focus groups with advisory committees, and carried out a thematic analysis of the information. RESULTS: The advisory groups considered the measurement scales to be unsafe. The major components that hindered their acceptance were: numeric rating, self-evaluation (versus supportive interaction), and a focus on symptoms rather than supportive factors. The participants preferred the Growth and Empowerment Measure due to its empowering approach. They voiced that it is necessary to develop a culturally sensitive and safe tool which facilitates interactions between the person and the practitioner. CONCLUSION: This project provides valuable information about the perspectives of local Indigenous peoples regarding mental health and factors of empowerment and resilience. The ideal tool should be flexible in terms of the content and its use as compared to the conventional psychometric strategies. A tool developed with the Indigenous perspective on wellbeing could be used in psychological and psychiatric intervention as well as in social and community services.


Subject(s)
Depression , Inuit , Depression/diagnosis , Focus Groups , Humans , Mental Health , Quebec
4.
Parasitol Res ; 120(1): 373-376, 2021 Jan.
Article in English | MEDLINE | ID: mdl-33155102

ABSTRACT

Despite significant advances in understanding the role of the immune response in Opisthorchis viverrini-associated carcinogenesis, little is known about how infection induces gall bladder disease. This study investigated whether mast cells are activated in cholecystitis associated with O. viverrini, gall bladder specimens from ninety-two patients who had undergone cholecystectomy at the Khon Kaen Regional Hospital, Khon Kaen, Thailand. Two representative sections from the body of fresh gall bladder tissue were fixed in Carnoy's solution and embedded in paraffin wax. The paraffin sections were stained for mast cells and IgE plasma cells by the double histochemical and immunohistochemical method. The cells in the epithelium, lamina propria, muscular layer, and subserosa were counted and expressed as cells per square millimeter. The gall bladder bile was examined for the presence of O. viverrini eggs. Significantly higher mean mast cell numbers were found in the lamina propria (221.41 ± 16.01 vs 116.97 ± 14.61 cells per mm2; P < 0.005) of egg positive compared to egg negative groups, respectively. No comparable differences in mast cell number were observed in other layers. IgE plasma cells were rarely seen. The results suggest that mast cell hyperplasia occurs during cholecystitis in association with opisthorchiasis and may play a role in the pathogenesis of the disease.


Subject(s)
Cholecystitis/pathology , Hyperplasia/parasitology , Mast Cells/pathology , Opisthorchiasis/pathology , Opisthorchis/isolation & purification , Adult , Animals , Bile/parasitology , Cholecystitis/parasitology , Feces/parasitology , Female , Humans , Hyperplasia/pathology , Immunoglobulin E/blood , Male , Middle Aged , Mucous Membrane/cytology , Mucous Membrane/parasitology , Thailand
5.
Rural Remote Health ; 21(3): 6078, 2021 07.
Article in English | MEDLINE | ID: mdl-34260859

ABSTRACT

INTRODUCTION: Unpaid carers have a crucial role in supporting older people with cognitive impairment and disability, but their own health and wellbeing are often impacted. There are limited data on how carer strain, depression and empowerment may be improved for carers. METHODS: This was a cluster randomised controlled trial to compare the effect of a carer support program developed with a community-based participatory action research (PAR) approach to the delivery of information sessions to 100 carers of people aged 45 years or more living in four remote Aboriginal communities in Western Australia. RESULTS: The mean age of carers was 38.3±14.9 years, 76% were female and 77% were children or grandchildren of the care recipient. Carer strain and empowerment measures did not change significantly between baseline and follow-up. A statistically significant decrease in depression scores was observed in the PAR group. However, decreases were observed in both the PAR and control groups, and the change in scores did not differ significantly between groups. Depression scores decreased most in those who had not attended high school. Overall, the proportion of participants meeting criteria for depression decreased from 18.8% at baseline to 8.3% at follow-up. CONCLUSION: A carer support program was of equivocal benefit, although this research demonstrates that the wellbeing of carers in remote Aboriginal communities can potentially be markedly improved by outreach strategies.


Subject(s)
Caregivers , Population Groups , Adult , Aged , Child , Empowerment , Family , Female , Humans , Middle Aged , Racial Groups , Young Adult
6.
Rural Remote Health ; 19(2): 4708, 2019 04.
Article in English | MEDLINE | ID: mdl-30987426

ABSTRACT

INTRODUCTION: Public health education strives to transform and empower students to engage in policy and practice improvement. However, little is known of the nature of such change among students, especially when studying Aboriginal health and wellbeing, which may involve disrupting long held assumptions and prejudices. This article reports findings regarding the feasibility, specificity and sensitivity of the Growth and Empowerment Measure (GEM) in the evaluation of two innovative Australian 13-week postgraduate public health electives focused on Aboriginal health and wellbeing. The GEM's 14-item Emotional Empowerment Scale (EES14) and its subscales Inner Peace and Self-Capacity, and 12 Scenarios (S12) and its subscales Healing and Growth and Connection and Purpose were used to examine transformative experiences. A new short form of the S12, the Core6, was also trialled as a briefer measure of functional empowerment. METHODS: Pre-course GEM responses and demographic information were collected from consenting students during the mandatory, face-to-face workshops of the Aboriginal public health Perspectives course and the Aboriginal empowerment and wellbeing Lifespan course. The two-day Perspectives course workshop introduced a group scenario-building activity towards ending health inequality. Lifespan students experienced a 3-day immersion based on Stage 1 of the Aboriginal Family Well Being empowerment program. Insights from both workshops were further integrated through structured online discussions and written assessments. At the end of semester, a post-course GEM was mailed to students for completion and return. Students could also provide feedback through evaluation surveys and semi-structured focus groups. Effect sizes were assessed using paired t-tests, Wilcoxon signed-rank tests and multiple ANOVA. Cronbach's alpha confirmed internal consistency. RESULTS: Baseline GEM data was provided for 147 out of a total of 194 workshop experiences from participating students. Twenty students attended workshops for both Perspectives and Lifespan. Fifty-five matched pairs (representing 52 individual participants) were obtained from 170 students who completed one or both courses. Statistically significant positive change of small to medium effect size was detected in all GEM scales, subscales and some individual items. Lifespan yielded larger effects than Perspectives, most markedly on two subscales: Inner Peace, and Connection and Purpose. Participating students reported significant growth in the Scenario item 'knowing and being who I am' following Perspectives and Lifespan. Those completing Perspectives also reported a significant increase in 'gaining voice and being heard', consistent with its action-oriented scenario-building assessment. In contrast, the psychosocial development approach embedded in Lifespan stimulated strong development in spirituality, responding constructively to judgement, appreciating empowerment in their communities and skills to make changes in their lives. Feedback indicated that students valued these personal and professional growth experiences. CONCLUSION: The GEM was sensitive and specific in measuring components of empowering change among participants. Challenges included low post-course response rates that limited extrapolation to overall course impact, and attention needed to starting point when comparing the increment of change. The GEM is a promising tool for studying postgraduate courses designed to stimulate transformative learning, wellbeing and cultural competence through empowerment, and relevant in the education of health professionals in the fields of Aboriginal and rural health.


Subject(s)
Cultural Competency/education , Education, Medical, Graduate/methods , Health Services, Indigenous , Native Hawaiian or Other Pacific Islander , Public Health/education , Adult , Aged , Education , Emotions , Empowerment , Female , Humans , Male , Middle Aged , Self Concept , Sensitivity and Specificity , Surveys and Questionnaires , Young Adult
7.
Rural Remote Health ; 16(4): 3825, 2016.
Article in English | MEDLINE | ID: mdl-27951725

ABSTRACT

CONTEXT: Many governments globally are investigating the benefits and risks associated with unconventional gas mining for shale, tight and coal seam gas (coalbed methane) to determine whether the industry should proceed in their jurisdiction. Most locations likely to be developed are in rural areas, with potential impact on farmers and small communities. Despite significant health concerns, public health knowledge and growing evidence are often overlooked in decision-making. It is difficult to gain a broad but accurate understanding of the health concerns for rural communities because the evidence has grown very recently and rapidly, is complex and largely based in the USA, where the industry is advanced. In 2016, a concerned South Australian beef and lamb farmer in an area targeted for potential unconventional gas development organised visits to homes in developed unconventional gas areas of Pennsylvania and forums with leading researchers and lawyers in Pennsylvania and New York. Guided by priorities identified during this trip, this communication concisely distils the research evidence on these key concerns, highlighting the Australian situation where evidence exists. It summarises key information of particular concern to rural regions, using Australia as an example, to assist rural health professionals to be better prepared to engage in decision-making and address the challenges associated with this new industry. ISSUES: Discussions with communities and experts, supported by the expanding research from the USA and Australia, revealed increasing health concerns in six key areas. These are absence of a safe solution to the toxic wastewater management problems, air pollution, land and water competition, mental health and psychosocial wellbeing risks, fugitive methane emissions and lack of proven regulatory regimes. Emerging epidemiological studies suggesting interference with foetal development and birth outcomes, and exacerbation of asthma conditions, are particularly concerning to rural families and livestock. LESSONS LEARNED: Rural residents in potentially affected areas should be supported to access and interpret the best current evidence regarding the multiple health concerns associated with unconventional gas mining. This knowledge should be part of wider discourse and decision-making processes driving local economic development and national and global energy choices.


Subject(s)
Environmental Exposure/prevention & control , Extraction and Processing Industry/standards , Natural Gas , Occupational Exposure/prevention & control , Occupational Health/standards , Rural Population/statistics & numerical data , Environmental Exposure/adverse effects , Female , Humans , International Cooperation , Male , Occupational Exposure/adverse effects , Risk Assessment , South Australia , United States
8.
Australas Psychiatry ; 21(5): 490-3, 2013 Oct.
Article in English | MEDLINE | ID: mdl-23884962

ABSTRACT

OBJECTIVES: Traditional indigenous society promoted the social and emotional well-being of indigenous men through the meeting of men in daily life and during ceremonial times. There is an increasing recognition that men's groups use similar mechanisms to enhance the social and emotional well-being of participants and their communities. This paper seeks to increase understanding of the processes and impacts of contemporary indigenous men's groups from an indigenous doctor's perspective. METHOD: Review of published and unpublished literature and reflections on the primary author's experiences within several indigenous men's groups using a participatory action research model were used to examine how participation within these groups can improve social and emotional well-being. RESULTS: There is a scarcity of published data on the distribution, activities and outcomes of indigenous men's groups. Published qualitative and experiential observations suggest that they contribute to improved social and emotional well-being for participants, their families and communities. CONCLUSIONS: Men's groups may be a good adjunct to the outpatient care of indigenous patients. As the published literature is entirely qualitative, mixed methods evaluation using appropriate and sensitive measures would assist in systematically capturing the impacts and outcomes of men's groups. Such evaluations could enhance programme longevity and encourage the referral of patients by mainstream mental health practitioners.


Subject(s)
Adaptation, Psychological , Men's Health , Population Groups/psychology , Self-Help Groups , Social Adjustment , Australia , Humans , Male
9.
Rural Remote Health ; 13(1): 2002, 2013.
Article in English | MEDLINE | ID: mdl-23374078

ABSTRACT

INTRODUCTION: Inaccuracy in identification of Indigenous status on health records hampers collection of the good quality data required to guide policies, programs and services. This study examined the use of an Indigenous Mental Health Worker Register to assess the level of correct identification of Indigenous status and sources of error among psychiatric admissions within a regional public hospital information system. METHOD: The study was conducted in 2004/2005 and 2005/2006 at the Cairns Base Hospital Mental Health Unit, Queensland, Australia, serving a population of 230,000 of which 13.2% identify as Aboriginal and/or Torres Strait Islander. Psychiatric admissions data, including Indigenous status, accessed from the hospital-based corporate information system (HBCIS) were compared with data collected through an Indigenous Mental Health Worker Register that is maintained through extensive networking. Investigation of mismatches enabled estimation of the frequency and sources of incorrect identification of Indigenous status and the impact of this on hospital statistics. RESULTS: Cross-validation of HBCIS data with the Indigenous Register over 2 years revealed 355 Indigenous admissions. Of the total 355 admissions, 301 (84.8%) were correctly identified and included in the hospital system, while 22 (6.2%) were designated non-Indigenous, 13 (3.7%) were 'unspecified' and 19 (5.4%) were missed through incorrect residence or admission designation. Among 1293 non-Indigenous admissions, 1.1% were incorrectly identified as Indigenous, while 25.5% of the 51 with unspecified status were found to be Indigenous. Furthermore, 45 Indigenous separations that had been missed over the previous 5 year period (1999/2000 to 2003/2004) were identified through careful examination of all those with unspecified status (n=174) and those with multiple separations of mixed designation of Indigenous status (n=15); all of the latter 15 were confirmed Indigenous by other mental health database and/or the Indigenous Mental Health Worker. Thus overall this study revealed a total of 89 Indigenous separations and 1261 occupied bed days in the 7 year period that had not be identified in the hospital information system. CONCLUSION: A novel method was used to ascertain the reliability of Indigenous status identification among mental health admissions within a hospital information system in a region with relatively high Indigenous population representation. This revealed that 85% of admissions were correctly identified over two consecutive years. Perhaps more importantly, the study confirmed a low frequency of false identification of non-Indigenous people as Aboriginal and/or Torres Strait Islander. The work has also demonstrated the value of involving Indigenous Mental Health Workers in routine processes to enhance, validate and improve Indigenous statistics and increase access to culturally informed care.


Subject(s)
Health Services, Indigenous , Hospitalization/statistics & numerical data , Hospitals, Psychiatric/statistics & numerical data , Mental Health Services , Native Hawaiian or Other Pacific Islander/psychology , Adult , Aged , Australia/ethnology , Benchmarking , Child , Female , Health Services, Indigenous/statistics & numerical data , Hospitals, Psychiatric/standards , Humans , Male , Middle Aged , Northern Territory/ethnology , Patient Admission/statistics & numerical data , Patient Admission/trends , Registries , Workforce
10.
Am J Trop Med Hyg ; 109(1): 159-165, 2023 07 05.
Article in English | MEDLINE | ID: mdl-37217166

ABSTRACT

Detection of worm antigen in urine is a sensitive diagnostic method for opisthorchiasis, particularly for light-intensity infections; however, the presence of eggs in feces is essential for validating results from the antigen assay. To address the issue of low sensitivity of fecal examination, we modified the protocol for the formalin-ethyl acetate concentration technique (FECT) and compared it against urine antigen measurements for detection of the parasite Opisthorchis viverrini. First, we optimized the FECT protocol by increasing the number of drops for examinations from the standard two drops to a maximum of eight. We were able to detect additional cases after examination of ≥ 3 drops, and the prevalence of O. viverrini saturated after examination of ≥ 5 drops. We then compared the optimized FECT protocol (examining five drops of suspension) against urine antigen detection for the diagnosis of opisthorchiasis in field-collected samples. The optimized FECT protocol detected O. viverrini eggs in 25 of 82 individuals (30.5%) who had positive urine antigen tests but were fecal egg negative by the standard FECT protocol. The optimized protocol also retrieved O. viverrini eggs in 2 of 80 antigen-negative cases (2.5%). In comparison with the composite reference standard (combined FECT and urine antigen detection), the diagnostic sensitivity of examining two and five drops of FECT and the urine assay was 58.2, 67, and 98.8%, respectively. Our results show that multiple examinations of fecal sediment increase the diagnostic sensitivity of FECT and thus provide further support for the reliability and utility of the antigen assay for diagnosis and screening of opisthorchiasis.


Subject(s)
Opisthorchiasis , Opisthorchis , Animals , Opisthorchiasis/epidemiology , Formaldehyde , Reproducibility of Results , Sensitivity and Specificity , Feces/parasitology , Thailand/epidemiology
11.
Sci Total Environ ; 850: 157978, 2022 Dec 01.
Article in English | MEDLINE | ID: mdl-35964755

ABSTRACT

Active mobility (AM), defined as walking and cycling for transportation, can improve health through increasing regular physical activity. However, these health improvements could be outweighed by harm from inhaling traffic-related air pollutants during AM participation. The interaction of AM and air pollutants on health is complex physiologically, manifesting as acute changes in health indicators that may lead to poor long-term health consequences. The aim of this study was to systematically review the current evidence of effect modification by air pollution (AP) on associations between AM and health indicators. Studies were included if they examined associations between AM and health indicators being modified by AP or, conversely, associations between AP and health indicators being modified by AM. Thirty-three studies met eligibility criteria. The main AP indicators studied were particulate matter, ultrafine particles, and nitrogen oxides. Most health indicators studied were grouped into cardiovascular and respiratory indicators. There is evidence of a reduction by AP, mainly ultrafine particles and PM2.5, in the short-term health benefits of AM. Multiple studies suggest that long-term health benefits of AM are not negatively associated with levels of the single traffic-related pollutant NO2. However, other studies reveal reduced long-term health benefits of AM in areas affected by high levels of pollutant mixtures. We recommend that future studies adopt consistent and rigorous study designs and include reporting of interaction testing, to advance understanding of the complex relationships between AM, AP, and health indicators.


Subject(s)
Air Pollutants , Air Pollution , Air Pollutants/adverse effects , Air Pollutants/analysis , Air Pollution/analysis , Environmental Exposure/analysis , Nitrogen Dioxide/analysis , Nitrogen Oxides , Particulate Matter/analysis , Vehicle Emissions/analysis
12.
Environ Monit Assess ; 172(1-4): 91-112, 2011 Jan.
Article in English | MEDLINE | ID: mdl-20145996

ABSTRACT

Dietary exposure of house wrens (Troglodytes aedon), tree swallows (Tachycineta bicolor), and eastern bluebirds (Sialia sialis) to polychlorinated dibenzofurans (PCDFs) and polychlorinated dibenzo-p-dioxins (PCDDs) near Midland, Michigan (USA) was evaluated based on site-specific data, including concentrations of residues in bolus samples and individual invertebrate orders and dietary compositions by study species. Site-specific dietary compositions for the three species were similar to those reported in the literature, but differed in their relative proportions of some dietary items. Oligocheata (non-depurated) and Brachycera (Diptera) contained the greatest average concentrations of ΣPCDD/DFs of the major site-specific dietary items collected via food web-based sampling. Average ingestion values of ΣPCDD/DFs from site-specific bolus-based and food web-based dietary concentrations for nestlings at study areas (SAs) were 6- to 20-fold and 2- to 9-fold greater than at proximally located reference areas (RAs), respectively. Average ingestion values of total 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQ(WHO - Avian)) from site-specific bolus-based and food web-based dietary concentrations for nestlings at SAs were 31- to 121-fold and 9- to 64-fold greater than at proximally located RAs, respectively. Estimates of ΣPCDD/DFs and TEQ(WHO - Avian) tissue concentrations based on nestling dietary exposures were greater than those measured. Plausible explanations include nestling metabolism of 2,3,7,8-tetrachlorodibenzofuran and assimilation rates of less than the 70% assumed to occur over the nestling growth period. Profiles of the relative concentrations of individual PCDD/DF congeners in samples of invertebrates and bolus at SAs on the Tittabawassee River downstream of the source of contamination were dominated by 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin (22% to 44%) and 2,3,7,8-tetrachlorodibenzofuran (18% to 50%).


Subject(s)
Benzofurans/analysis , Polychlorinated Dibenzodioxins/analogs & derivatives , Water Pollutants, Chemical/analysis , Animals , Dibenzofurans, Polychlorinated , Environmental Monitoring , Food Chain , Food Contamination/analysis , Michigan , Polychlorinated Dibenzodioxins/analysis , Songbirds , Swallows
13.
J Appl Gerontol ; 40(7): 693-702, 2021 07.
Article in English | MEDLINE | ID: mdl-31920136

ABSTRACT

Objective: To describe demographic features and well-being of carers of Aboriginal Australians aged ≥45 years in remote Western Australia. Method: Carer burden, empowerment, and depression were assessed in 124 Aboriginal carers in four remote Aboriginal communities. Results: Carers were aged 38.8 ± 15.0 years, 73.4% were female, and 75.8% were children or grandchildren of the person cared for. The mean Zarit-6 score was 3.7 ± 3.6. Attending high school (odds ratio [OR] = 0.3; 95% confidence interval [CI] = [0.1, 0.7]) and feeling empowered (OR = 0.2; 95% CI = [0.1, 0.8]) were inversely associated with carer burden; female carers were less likely to feel empowered (OR = 0.4; 95% CI = [0.2, 0.9]); and empowerment was inversely associated with depression (OR = 0.3; 95% CI = [0.1, 0.7]). Discussion: Aboriginal carers in remote communities are relatively young and most are children or grandchildren. Carer burden was lower than anticipated. However, existing tools may not adequately measure Aboriginal perspectives. Education and empowerment are key factors which support programs must consider.


Subject(s)
Caregivers , Depression , Australia , Female , Humans , Native Hawaiian or Other Pacific Islander , Western Australia
14.
Aust N Z J Psychiatry ; 44(9): 791-9, 2010 Sep.
Article in English | MEDLINE | ID: mdl-20815665

ABSTRACT

OBJECTIVE: Empowerment is a complex process of psychological, social, organizational and structural change. It allows individuals and groups to achieve positive growth and effectively address the social and psychological impacts of historical oppression, marginalization and disadvantage. The Growth and Empowerment Measure (GEM) was developed to measure change in dimensions of empowerment as defined and described by Aboriginal Australians who participated in the Family Well Being programme. METHOD: The GEM has two components: a 14-item Emotional Empowerment Scale (EES14) and 12 Scenarios (12S). It is accompanied by the Kessler 6 Psychological Distress Scale (K6), supplemented by two questions assessing frequency of happy and angry feelings. For validation, the measure was applied with 184 Indigenous Australian participants involved in personal and/or organizational social health activities. RESULTS: Psychometric analyses of the new instruments support their validity and reliability and indicate two-component structures for both the EES (Self-capacity; Inner peace) and the 12S (Healing and enabling growth, Connection and purpose). Strong correlations were observed across the scales and subscales. Participants who scored higher on the newly developed scales showed lower distress on the K6, particularly when the two additional questions were included. However, exploratory factor analyses demonstrated that GEM subscales are separable from the Kessler distress measure. CONCLUSION: The GEM shows promise in enabling measurement and enhancing understanding of both process and outcome of psychological and social empowerment within an Australian Indigenous context.


Subject(s)
Emotions , Native Hawaiian or Other Pacific Islander/psychology , Personal Satisfaction , Power, Psychological , Adult , Australia/ethnology , Female , Humans , Male , Middle Aged , Psychiatric Status Rating Scales , Psychometrics , Reproducibility of Results , Surveys and Questionnaires
16.
Adv Parasitol ; 101: 41-67, 2018.
Article in English | MEDLINE | ID: mdl-29907255

ABSTRACT

Opisthorchiasis in the Lower Mekong Subregion is a parasitic disease caused by the liver fluke Opisthorchis viverrini. This parasite has a well-documented distribution in Thailand, Lao PDR, Cambodia, Myanmar and Southern Vietnam. In this chapter, we describe the current knowledge of the epidemiology of O. viverrini infection, highlighting advances in control efforts made in the last four decades in Thailand and identifying ongoing gaps in our epidemiological knowledge which need to be filled to support efforts to permanently overcome the heavy morbidity and mortality burden caused by these parasites within their endemic regions.


Subject(s)
Opisthorchiasis/epidemiology , Animals , Humans , Opisthorchiasis/mortality , Opisthorchis , Prevalence , Research/trends , Thailand/epidemiology
17.
Adv Parasitol ; 102: 73-95, 2018.
Article in English | MEDLINE | ID: mdl-30442311

ABSTRACT

Human liver fluke infection caused by Opisthorchis viverrini is a major public health problem in Mekong countries such as Thailand, Laos, Cambodia, Vietnam, and Myanmar with over 10 million infected through consumption of fish containing infective metacercariae. With no tissue migration phase and living entirely within the larger secondary (intrahepatic) bile ducts, liver flukes are only exposed to a biliary mucosal immune response, while their excretory and secretory products also stimulate chronic inflammation of biliary epithelium. Neither mucosal nor tissue immune responses appear to cause parasite death or protect against newly established flukes, as evidenced by the persistence of infection for decades in the body and rapid reinfection following treatment. Experimental studies suggest that specific immune suppressive mechanisms may promote parasite persistence, therefore allowing continued secretion of parasite products that damage the biliary epithelium, both directly through mechanical damage and mitogenicity and through innate and adaptive inflammatory responses. Chronic infection is associated with several hepatobiliary diseases, specifically gallbladder and bile duct inflammation (cholecystitis and cholangitis), periductal fibrosis, and cholangiocarcinoma, the fatal bile duct cancer. Various studies have linked the chronic immune response to parasite antigens to both fibrosis and many steps in the carcinogenic process. Here, we review research-based understandings of the basic immune response to liver fluke infection and its roles in host protection and immunopathogenesis from available literature and also from recent studies conducted by the authors.


Subject(s)
Opisthorchiasis/immunology , Opisthorchiasis/pathology , Opisthorchis , Animals , Humans , Liver Diseases/etiology , Liver Diseases/immunology , Liver Diseases/pathology , Opisthorchiasis/complications , Opisthorchis/immunology
18.
Aust N Z J Public Health ; 40 Suppl 1: S53-8, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26123691

ABSTRACT

OBJECTIVE: To evaluate the first three years of a national program to improve the social and emotional wellbeing of Indigenous youth in remote and regional Australia. METHODS: Combination of open inquiry and audit review involving investigation of process and outcomes, with a broad national overview supplemented by five in-depth case studies in diverse settings. RESULTS: Community development principles were applied at all 14 sites. There were many examples of collaborative, community-driven health promotion initiatives, with most progress observed where there were strong local partnerships. Within the range of activities, education sessions on alcohol and other drugs, mental health and violence were facilitated by program staff. There was a tension between community development and specific program delivery, with the balance reflecting the needs and capacity of individual sites, program staff expertise and contractual requirements. CONCLUSIONS AND IMPLICATIONS: The main lessons concern program design and resourcing and ways of working. Program staff at each site learned to be not too ambitious, but to work consistently with the community, establishing partnerships and engaging and training community members. Community and stakeholder capacity enhancement should be regarded as core, and evaluation built in. Activities directed at youth must be engaging and effective, and integrated with other programs and services.


Subject(s)
Cooperative Behavior , Emotions , Health Promotion , Native Hawaiian or Other Pacific Islander/psychology , Program Evaluation/methods , Social Problems , Adolescent , Australia , Focus Groups , Humans , Interviews as Topic , Mental Health , Personal Satisfaction , Qualitative Research , Residence Characteristics , Rural Population , Social Conditions , Surveys and Questionnaires
19.
Aust N Z J Public Health ; 40 Suppl 1: S115-21, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26337824

ABSTRACT

OBJECTIVES: To evaluate an urban art-based community health program (Ngala Nanga Mai; We Dream) that seeks to improve health, education, empowerment and connectedness of Aboriginal parents by describing paediatric health service attendance, maternal educational engagement, participant growth and empowerment, and worker and participant experiences. METHODS: Mixed methods were used. Qualitative data was collected through interviews and focus groups. Demographics, health service use and child health status were extracted from clinical records. Psycho-social empowerment and wellbeing was measured using the Growth and Empowerment Measure (GEM). A Critical Effectiveness Factor framework that measures factors necessary for success, effectiveness and sustainability was used to assess program quality. RESULTS: Between 2009 and 2012, 92 Aboriginal parents participated. A total of 93.5% of regular participants engaged their children at least once with paediatric health services and 27.1% undertook further education. Empowerment scores significantly improved, despite little change in psychological distress. The program operationalised all 10 Critical Effectiveness Factors for youth wellbeing. CONCLUSIONS: Ngala Nanga Mai creates an environment of social connectedness, strengthened parenting, maternal and child wellbeing and empowerment. It supports increased utilisation of health, education and support services, and early detection of treatable child health issues. IMPLICATIONS: Improving the health of Aboriginal children requires new strategies and learning from innovative programs. Solid baseline data, long-term follow-up data and meaningful health outcome data are critical to improving services and health outcomes at the program level. Ultimately, long-term commitment to adequate resourcing is needed in order to deliver broader improvement of child health outcomes.


Subject(s)
Health Services Accessibility , Native Hawaiian or Other Pacific Islander/psychology , Parents , Power, Psychological , Program Evaluation/methods , Adolescent , Adult , Child , Child Health Services , Female , Focus Groups , Health Promotion , Humans , Male , Parents/education , Parents/psychology , Qualitative Research , Retrospective Studies , Urban Population
20.
Glob Health Promot ; 19(4): 29-40, 2012 Dec.
Article in English | MEDLINE | ID: mdl-24803441

ABSTRACT

Most policies addressing Aboriginal health in Australia promote initiatives that are based on empowerment principles. Articulated programme components are necessary to support personal and group empowerment and to assist individuals in gaining the sense of control and purposefulness needed to exert their political and personal power in the face of the severe stress and powerlessness faced by the Australian Aboriginal people. This paper aims to provide a detailed description of the mechanisms underpinning a 'bottom-up' empowerment initiative, the Family well-being empowerment and leadership programme (FWB), and to analyze how the programme supports empowerment. The five stages of FWB were described and the validity of this model was assessed through the combination of participatory observation, documentation analysis, literature review, semi-structured interviews and iterative feedback with different analytical perspectives. Our study results articulated four distinct programme components: the setting plus inter-relational, educational and experiential actions. FWB is an example of the promotion of both outcome and process pathways towards empowerment. Potential applications of the programme are discussed.


Subject(s)
Family , Health Promotion , Leadership , Native Hawaiian or Other Pacific Islander , Personal Satisfaction , Power, Psychological , Australia , Capacity Building , Humans , Native Hawaiian or Other Pacific Islander/psychology , Program Development
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