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1.

ATF6 protects against protein misfolding during cardiac hypertrophy.

Hofmann, Christoph; Aghajani, Marjan; Alcock, Cecily D; Blackwood, Erik A; Sandmann, Clara; Herzog, Nicole; Groß, Julia; Plate, Lars; Wiseman, R Luke; Kaufman, Randal J; Katus, Hugo A; Jakobi, Tobias; Völkers, Mirko; Glembotski, Christopher C; Doroudgar, Shirin.

J Mol Cell Cardiol ; 189: 12-24, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38401179

2.

Long-term use of everolimus for refractory arrhythmia in a child with tuberous sclerosis complex.

Hofmann, Christoph; Syrbe, Steffen; Hebe, Joachim; Kreft, Jannis; Stark, Sebastian; Milde, Till; Völkers, Mirko; Hoffmann, Georg Friedrich; Gorenflo, Matthias; Kovacevic, Alexander.

Am J Med Genet A ; 194(5): e63508, 2024 May.

Article in English | MEDLINE | ID: mdl-38130096

3.

mTORC1 inhibition impairs activation of the unfolded protein response and induces cell death during ER stress in cardiomyocytes.

Hofmann, Christoph; Löwenthal, Zoe; Aghajani, Marjan; Kaufman, Randal J; Katus, Hugo A; Frey, Norbert; Glembotski, Christopher C; Völkers, Mirko; Doroudgar, Shirin.

Am J Physiol Heart Circ Physiol ; 325(2): H311-H320, 2023 08 01.

Article in English | MEDLINE | ID: mdl-37294892

4.

Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo.

Varma, Eshita; Burghaus, Jana; Schwarzl, Thomas; Sekaran, Thileepan; Gupta, Parul; Górska, Agnieszka A; Hofmann, Christoph; Stroh, Claudia; Jürgensen, Lonny; Kamuf-Schenk, Verena; Li, Xue; Medert, Rebekka; Leuschner, Florian; Kmietczyk, Vivien; Freichel, Marc; Katus, Hugo A; Hentze, Matthias W; Frey, Norbert; Völkers, Mirko.

Basic Res Cardiol ; 118(1): 25, 2023 06 28.

Article in English | MEDLINE | ID: mdl-37378715

5.

Muscle-specific Cand2 is translationally upregulated by mTORC1 and promotes adverse cardiac remodeling.

Górska, Agnieszka A; Sandmann, Clara; Riechert, Eva; Hofmann, Christoph; Malovrh, Ellen; Varma, Eshita; Kmietczyk, Vivien; Ölschläger, Julie; Jürgensen, Lonny; Kamuf-Schenk, Verena; Stroh, Claudia; Furkel, Jennifer; Konstandin, Mathias H; Sticht, Carsten; Boileau, Etienne; Dieterich, Christoph; Frey, Norbert; Katus, Hugo A; Doroudgar, Shirin; Völkers, Mirko.

EMBO Rep ; 22(12): e52170, 2021 12 06.

Article in English | MEDLINE | ID: mdl-34605609

6.

Monitoring Cell-Type-Specific Gene Expression Using Ribosome Profiling In Vivo During Cardiac Hemodynamic Stress.

Doroudgar, Shirin; Hofmann, Christoph; Boileau, Etienne; Malone, Brandon; Riechert, Eva; Gorska, Agnieszka A; Jakobi, Tobias; Sandmann, Clara; Jürgensen, Lonny; Kmietczyk, Vivien; Malovrh, Ellen; Burghaus, Jana; Rettel, Mandy; Stein, Frank; Younesi, Fereshteh; Friedrich, Ulrike A; Mauz, Victoria; Backs, Johannes; Kramer, Günter; Katus, Hugo A; Dieterich, Christoph; Völkers, Mirko.

Circ Res ; 125(4): 431-448, 2019 08 02.

Article in English | MEDLINE | ID: mdl-31284834

7.

ATF6 Regulates Cardiac Hypertrophy by Transcriptional Induction of the mTORC1 Activator, Rheb.

Blackwood, Erik A; Hofmann, Christoph; Santo Domingo, Michelle; Bilal, Alina S; Sarakki, Anup; Stauffer, Winston; Arrieta, Adrian; Thuerauf, Donna J; Kolkhorst, Fred W; Müller, Oliver J; Jakobi, Tobias; Dieterich, Christoph; Katus, Hugo A; Doroudgar, Shirin; Glembotski, Christopher C.

Circ Res ; 124(1): 79-93, 2019 01 04.

Article in English | MEDLINE | ID: mdl-30582446

8.

Saraf-dependent activation of mTORC1 regulates cardiac growth.

Sanlialp, Ayse; Schumacher, Dagmar; Kiper, Leon; Varma, Eshita; Riechert, Eva; Ho, Thanh Cao; Hofmann, Christoph; Kmietczyk, Vivien; Zimmermann, Frank; Dlugosz, Sascha; Wirth, Angela; Gorska, Agnieszka A; Burghaus, Jana; Camacho Londoño, Juan E; Katus, Hugo A; Doroudgar, Shirin; Freichel, Marc; Völkers, Mirko.

J Mol Cell Cardiol ; 141: 30-42, 2020 04.

Article in English | MEDLINE | ID: mdl-32173353

9.

ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart.

Jin, Jung-Kang; Blackwood, Erik A; Azizi, Khalid; Thuerauf, Donna J; Fahem, Asal G; Hofmann, Christoph; Kaufman, Randal J; Doroudgar, Shirin; Glembotski, Christopher C.

Circ Res ; 120(5): 862-875, 2017 Mar 03.

Article in English | MEDLINE | ID: mdl-27932512

10.

Protein Misfolding in Cardiac Disease.

Hofmann, Christoph; Katus, Hugo A; Doroudgar, Shirin.

Circulation ; 139(18): 2085-2088, 2019 04 30.

Article in English | MEDLINE | ID: mdl-31034286

11.

Targeting coagulation in heart failure with preserved ejection fraction and cardiac fibrosis.

Hofmann, Christoph; Völkers, Mirko; Katus, Hugo A.

Eur Heart J ; 40(40): 3333-3335, 2019 10 21.

Article in English | MEDLINE | ID: mdl-31324909

12.

Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes.

Riechert, Eva; Kmietczyk, Vivien; Stein, Frank; Schwarzl, Thomas; Sekaran, Thileepan; Jürgensen, Lonny; Kamuf-Schenk, Verena; Varma, Eshita; Hofmann, Christoph; Rettel, Mandy; Gür, Kira; Ölschläger, Julie; Kühl, Friederike; Martin, Judit; Ramirez-Pedraza, Marta; Fernandez, Mercedes; Doroudgar, Shirin; Méndez, Raúl; Katus, Hugo A; Hentze, Matthias W; Völkers, Mirko.

Cell Rep ; 35(6): 109100, 2021 05 11.

Article in English | MEDLINE | ID: mdl-33979607

13.

Evidence of antiblockade in an ultracold Rydberg gas.

Amthor, Thomas; Giese, Christian; Hofmann, Christoph S; Weidemüller, Matthias.

Phys Rev Lett ; 104(1): 013001, 2010 Jan 08.

Article in English | MEDLINE | ID: mdl-20366361

14.

m⁶A-mRNA methylation regulates cardiac gene expression and cellular growth.

Kmietczyk, Vivien; Riechert, Eva; Kalinski, Laura; Boileau, Etienne; Malovrh, Ellen; Malone, Brandon; Gorska, Agnieszka; Hofmann, Christoph; Varma, Eshita; Jürgensen, Lonny; Kamuf-Schenk, Verena; Altmüller, Janine; Tappu, Rewati; Busch, Martin; Most, Patrick; Katus, Hugo A; Dieterich, Christoph; Völkers, Mirko.

Life Sci Alliance ; 2(2)2019 04.

Article in English | MEDLINE | ID: mdl-30967445

15.

Versatile cold atom target apparatus.

Götz, Simone; Höltkemeier, Bastian; Hofmann, Christoph S; Litsch, Dominic; DePaola, Brett D; Weidemüller, Matthias.

Rev Sci Instrum ; 83(7): 073112, 2012 Jul.

Article in English | MEDLINE | ID: mdl-22852676

16.

High-precision semiconductor wavelength sensor based on a double-layer photo diode.

Amthor, Thomas; Hofmann, Christoph S; Knorz, Jürgen; Weidemüller, Matthias.

Rev Sci Instrum ; 82(9): 093111, 2011 Sep.

Article in English | MEDLINE | ID: mdl-21974577

17.

Scanning malleable transition state ensembles: comparing theory and experiment for folding protein U1A.

Shen, Tongye; Hofmann, Christoph P; Oliveberg, Mikael; Wolynes, Peter G.

Biochemistry ; 44(17): 6433-9, 2005 May 03.

Article in English | MEDLINE | ID: mdl-15850377

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