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1.

The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations.

Åsenius, Fredrika; Gorrie-Stone, Tyler J; Brew, Ama; Panchbhaya, Yasmin; Williamson, Elizabeth; Schalkwyk, Leonard C; Rakyan, Vardhman K; Holland, Michelle L; Marzi, Sarah J; Williams, David J.

PLoS Genet ; 16(10): e1009035, 2020 10.

Article in English | MEDLINE | ID: mdl-33048947

2.

Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes.

Proudhon, Charlotte; Duffié, Rachel; Ajjan, Sophie; Cowley, Michael; Iranzo, Julian; Carbajosa, Guillermo; Saadeh, Heba; Holland, Michelle L; Oakey, Rebecca J; Rakyan, Vardhman K; Schulz, Reiner; Bourc'his, Déborah.

Mol Cell ; 47(6): 909-20, 2012 Sep 28.

Article in English | MEDLINE | ID: mdl-22902559

3.

Early life diet conditions the molecular response to post-weaning protein restriction in the mouse.

Danson, Amy F; Marzi, Sarah J; Lowe, Robert; Holland, Michelle L; Rakyan, Vardhman K.

BMC Biol ; 16(1): 51, 2018 05 02.

Article in English | MEDLINE | ID: mdl-29720174

4.

Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development.

Lowe, Robert; Gemma, Carolina; Rakyan, Vardhman K; Holland, Michelle L.

BMC Genomics ; 16: 295, 2015 Apr 14.

Article in English | MEDLINE | ID: mdl-25888192

5.

Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans.

Beyan, Huriya; Down, Thomas A; Ramagopalan, Sreeram V; Uvebrant, Kristina; Nilsson, Anita; Holland, Michelle L; Gemma, Carolina; Giovannoni, Gavin; Boehm, Bernhard O; Ebers, George C; Lernmark, Åke; Cilio, Corrado M; Leslie, R David; Rakyan, Vardhman K.

Genome Res ; 22(11): 2138-45, 2012 Nov.

Article in English | MEDLINE | ID: mdl-22919074

6.

Transgenerational inheritance of non-genetically determined phenotypes.

Holland, Michelle L; Rakyan, Vardhman K.

Biochem Soc Trans ; 41(3): 769-76, 2013 Jun.

Article in English | MEDLINE | ID: mdl-23697936

7.

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states.

Rodriguez-Algarra, Francisco; Seaborne, Robert A E; Danson, Amy F; Yildizoglu, Selin; Yoshikawa, Harunori; Law, Pui Pik; Ahmad, Zakaryya; Maudsley, Victoria A; Brew, Ama; Holmes, Nadine; Ochôa, Mateus; Hodgkinson, Alan; Marzi, Sarah J; Pradeepa, Madapura M; Loose, Matthew; Holland, Michelle L; Rakyan, Vardhman K.

Genome Biol ; 23(1): 54, 2022 02 14.

Article in English | MEDLINE | ID: mdl-35164830

8.

Identification of the transcription factor MAZ as a regulator of erythropoiesis.

Deen, Darya; Butter, Falk; Daniels, Deborah E; Ferrer-Vicens, Ivan; Ferguson, Daniel C J; Holland, Michelle L; Samara, Vasiliki; Sloane-Stanley, Jacqueline A; Ayyub, Helena; Mann, Matthias; Frayne, Jan; Garrick, David; Vernimmen, Douglas.

Blood Adv ; 5(15): 3002-3015, 2021 08 10.

Article in English | MEDLINE | ID: mdl-34351390

9.

DNA methylation at the crossroads of gene and environment interactions.

Law, Pui-Pik; Holland, Michelle L.

Essays Biochem ; 63(6): 717-726, 2019 12 20.

Article in English | MEDLINE | ID: mdl-31782496

10.

Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1).

Holland, Michelle L; Allen, John D; Arnold, Jonathon C.

Eur J Pharmacol ; 591(1-3): 128-31, 2008 Sep 04.

Article in English | MEDLINE | ID: mdl-18619955

11.

Deciphering the Role of the Non-Coding Genome in Regulating Gene-Diet Interactions.

Law, Pui-Pik; Holland, Michelle L.

Nutrients ; 10(12)2018 Nov 27.

Article in English | MEDLINE | ID: mdl-30486341

12.

A stochastic basis for metabolic phenotypes.

Holland, Michelle L; Rakyan, Vardhman K.

Nat Metab ; 4(9): 1091-1092, 2022 09.

Article in English | MEDLINE | ID: mdl-36097184

13.

Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice.

Holland, Michelle L; Lowe, Robert; Caton, Paul W; Gemma, Carolina; Carbajosa, Guillermo; Danson, Amy F; Carpenter, Asha A M; Loche, Elena; Ozanne, Susan E; Rakyan, Vardhman K.

Science ; 353(6298): 495-8, 2016 Jul 29.

Article in English | MEDLINE | ID: mdl-27386920

14.

Inactive or moderately active human promoters are enriched for inter-individual epialleles.

Gemma, Carolina; Ramagopalan, Sreeram V; Down, Thomas A; Beyan, Huriya; Hawa, Mohammed I; Holland, Michelle L; Hurd, Paul J; Giovannoni, Gavin; Leslie, R David; Ebers, George C; Rakyan, Vardhman K.

Genome Biol ; 14(5): R43, 2013 May 25.

Article in English | MEDLINE | ID: mdl-23706135

15.

Epigenetic Regulation of the Protein Translation Machinery.

Holland, Michelle L.

EBioMedicine ; 17: 3-4, 2017 Mar.

Article in English | MEDLINE | ID: mdl-28238697

16.

CB2 and TRPV1 receptors mediate cannabinoid actions on MDR1 expression in multidrug resistant cells.

Arnold, Jonathon C; Hone, Phoebe; Holland, Michelle L; Allen, John D.

Pharmacol Rep ; 64(3): 751-7, 2012.

Article in English | MEDLINE | ID: mdl-22814029

17.

High-resolution analysis of cytosine methylation in ancient DNA.

Llamas, Bastien; Holland, Michelle L; Chen, Kefei; Cropley, Jennifer E; Cooper, Alan; Suter, Catherine M.

PLoS One ; 7(1): e30226, 2012.

Article in English | MEDLINE | ID: mdl-22276161

18.

The hunt for the epiallele.

Finer, Sarah; Holland, Michelle L; Nanty, Lisa; Rakyan, Vardhman K.

Environ Mol Mutagen ; 52(1): 1-11, 2011 Jan.

Article in English | MEDLINE | ID: mdl-20839222

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