Search details
1.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
; 584(7822): 614-618, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32612233
2.
Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques.
J Virol
; : e0029424, 2024 Jun 03.
Article
in English
| MEDLINE | ID: mdl-38829139
3.
HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys.
PLoS Pathog
; 18(4): e1010467, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35452496
4.
Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B.
Hepatology
; 73(1): 53-67, 2021 01.
Article
in English
| MEDLINE | ID: mdl-32246499
5.
Hepatitis B core-specific memory B cell responses associate with clinical parameters in patients with chronic HBV.
J Hepatol
; 73(1): 52-61, 2020 07.
Article
in English
| MEDLINE | ID: mdl-32061650
6.
Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B.
J Hepatol
; 72(1): 34-44, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31348999
7.
Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes.
J Virol
; 93(16)2019 08 15.
Article
in English
| MEDLINE | ID: mdl-31167911
8.
PD-1 Blockade and TLR7 Activation Lack Therapeutic Benefit in Chronic Simian Immunodeficiency Virus-Infected Macaques on Antiretroviral Therapy.
Antimicrob Agents Chemother
; 63(11)2019 11.
Article
in English
| MEDLINE | ID: mdl-31501143
9.
Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.
Bioorg Med Chem
; 27(3): 457-469, 2019 02 01.
Article
in English
| MEDLINE | ID: mdl-30606676
10.
Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9.
J Biol Chem
; 292(16): 6810-6820, 2017 04 21.
Article
in English
| MEDLINE | ID: mdl-28235803
11.
Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII).
Bioorg Med Chem Lett
; 28(3): 541-546, 2018 02 01.
Article
in English
| MEDLINE | ID: mdl-29254643
12.
Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assembly.
Biochemistry
; 54(13): 2240-8, 2015 Apr 07.
Article
in English
| MEDLINE | ID: mdl-25774576
13.
Binding kinetics, potency, and selectivity of the hepatitis C virus NS3 protease inhibitors GS-9256 and vedroprevir.
Biochim Biophys Acta
; 1840(12): 3292-8, 2014 Dec.
Article
in English
| MEDLINE | ID: mdl-25139683
14.
GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein.
Antimicrob Agents Chemother
; 59(11): 7109-12, 2015 Nov.
Article
in English
| MEDLINE | ID: mdl-26324264
15.
Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.
Antimicrob Agents Chemother
; 58(4): 1930-42, 2014.
Article
in English
| MEDLINE | ID: mdl-24419349
16.
New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.
J Biol Chem
; 287(25): 21189-203, 2012 Jun 15.
Article
in English
| MEDLINE | ID: mdl-22535962
17.
A trimer of dimers is the basic building block for human immunodeficiency virus-1 capsid assembly.
Biochemistry
; 51(22): 4416-28, 2012 Jun 05.
Article
in English
| MEDLINE | ID: mdl-22564075
18.
Effects of small molecule-induced dimerization on the programmed death ligand 1 protein life cycle.
Sci Rep
; 12(1): 21286, 2022 12 09.
Article
in English
| MEDLINE | ID: mdl-36494467
19.
Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.
Biochemistry
; 50(10): 1567-81, 2011 Mar 15.
Article
in English
| MEDLINE | ID: mdl-21222490
20.
Affinities between the binding partners of the HIV-1 integrase dimer-lens epithelium-derived growth factor (IN dimer-LEDGF) complex.
J Biol Chem
; 284(48): 33580-99, 2009 Nov 27.
Article
in English
| MEDLINE | ID: mdl-19801648