Search details
1.
Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease.
Cell
; 183(6): 1699-1713.e13, 2020 12 10.
Article
in English
| MEDLINE | ID: mdl-33188775
2.
Somatic genomic changes in single Alzheimer's disease neurons.
Nature
; 604(7907): 714-722, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35444284
3.
LRP1 is a master regulator of tau uptake and spread.
Nature
; 580(7803): 381-385, 2020 04.
Article
in English
| MEDLINE | ID: mdl-32296178
4.
SORL1 is a receptor for tau that promotes tau seeding.
J Biol Chem
; 300(6): 107313, 2024 Apr 23.
Article
in English
| MEDLINE | ID: mdl-38657864
5.
Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease.
Ann Neurol
; 95(4): 625-634, 2024 Apr.
Article
in English
| MEDLINE | ID: mdl-38180638
6.
Alzheimer proteopathic tau seeds are biochemically a forme fruste of mature paired helical filaments.
Brain
; 147(2): 637-648, 2024 02 01.
Article
in English
| MEDLINE | ID: mdl-38236720
7.
Utility of cortical tissue analysis in normal pressure hydrocephalus.
Cereb Cortex
; 34(2)2024 01 31.
Article
in English
| MEDLINE | ID: mdl-38275188
8.
APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.
Mol Ther
; 32(5): 1373-1386, 2024 May 01.
Article
in English
| MEDLINE | ID: mdl-38504517
9.
Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease.
J Neurosci
; 43(24): 4541-4557, 2023 06 14.
Article
in English
| MEDLINE | ID: mdl-37208174
10.
Reconstitution of the Alzheimer's Disease Tau Core Structure from Recombinant Tau297-391 Yields Variable Quaternary Structures as Seen by Negative Stain and Cryo-EM.
Biochemistry
; 63(2): 194-201, 2024 Jan 16.
Article
in English
| MEDLINE | ID: mdl-38154792
11.
Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer's disease and related dementias.
Acta Neuropathol
; 147(1): 66, 2024 04 03.
Article
in English
| MEDLINE | ID: mdl-38568475
12.
Brain vasculature accumulates tau and is spatially related to tau tangle pathology in Alzheimer's disease.
Acta Neuropathol
; 147(1): 101, 2024 06 17.
Article
in English
| MEDLINE | ID: mdl-38884806
13.
Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia.
Acta Neuropathol
; 147(1): 56, 2024 03 13.
Article
in English
| MEDLINE | ID: mdl-38478117
14.
Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aß and tau.
Acta Neuropathol
; 147(1): 65, 2024 04 01.
Article
in English
| MEDLINE | ID: mdl-38557897
15.
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease.
Acta Neuropathol
; 147(1): 9, 2024 01 04.
Article
in English
| MEDLINE | ID: mdl-38175301
16.
Beyond the neuron-cellular interactions early in Alzheimer disease pathogenesis.
Nat Rev Neurosci
; 20(2): 94-108, 2019 02.
Article
in English
| MEDLINE | ID: mdl-30643230
17.
Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis.
Cereb Cortex
; 33(23): 11400-11407, 2023 11 27.
Article
in English
| MEDLINE | ID: mdl-37814356
18.
Distinct transcriptomic responses to Aß plaques, neurofibrillary tangles, and APOE in Alzheimer's disease.
Alzheimers Dement
; 20(1): 74-90, 2024 Jan.
Article
in English
| MEDLINE | ID: mdl-37461318
19.
Lewy body dementia: Overcoming barriers and identifying solutions.
Alzheimers Dement
; 20(3): 2298-2308, 2024 Mar.
Article
in English
| MEDLINE | ID: mdl-38265159
20.
Size matters: the impact of nucleus size on results from spatial transcriptomics.
J Transl Med
; 21(1): 270, 2023 04 21.
Article
in English
| MEDLINE | ID: mdl-37081484