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1.

Monitoring synaptic pathology in Alzheimer's disease through fluid and PET imaging biomarkers: a comprehensive review and future perspectives.

Lista, Simone; Santos-Lozano, Alejandro; Emanuele, Enzo; Mercuri, Nicola B; Gabelle, Audrey; López-Ortiz, Susana; Martín-Hernández, Juan; Maisto, Nunzia; Imbimbo, Camillo; Caraci, Filippo; Imbimbo, Bruno P; Zetterberg, Henrik; Nisticò, Robert.

Mol Psychiatry ; 29(3): 847-857, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38228892

2.

Evidence for reduced anti-inflammatory microglial phagocytic response in late-life major depression.

Reichert Plaska, Chelsea; Heslegrave, Amanda; Bruno, Davide; Ramos-Cejudo, Jaime; Han Lee, Sang; Osorio, Ricardo; Imbimbo, Bruno P; Zetterberg, Henrik; Blennow, Kaj; Pomara, Nunzio.

Brain Behav Immun ; 120: 248-255, 2024 May 23.

Article in English | MEDLINE | ID: mdl-38795783

3.

Role of monomeric amyloid-ß in cognitive performance in Alzheimer's disease: Insights from clinical trials with secretase inhibitors and monoclonal antibodies.

Imbimbo, Bruno P; Ippati, Stefania; Watling, Mark; Imbimbo, Camillo.

Pharmacol Res ; 187: 106631, 2023 01.

Article in English | MEDLINE | ID: mdl-36586644

4.

Plasma ATN(I) classification and precision pharmacology in Alzheimer's disease.

Imbimbo, Bruno P; Watling, Mark; Imbimbo, Camillo; Nisticò, Robert.

Alzheimers Dement ; 19(10): 4729-4734, 2023 10.

Article in English | MEDLINE | ID: mdl-37079778

5.

A critical appraisal of tau-targeting therapies for primary and secondary tauopathies.

Imbimbo, Bruno P; Ippati, Stefania; Watling, Mark; Balducci, Claudia.

Alzheimers Dement ; 18(5): 1008-1037, 2022 05.

Article in English | MEDLINE | ID: mdl-34533272

6.

Lecanemab in Early Alzheimer's Disease.

Pomara, Nunzio; Imbimbo, Bruno P.

N Engl J Med ; 388(17): 1630-1631, 2023 Apr 27.

Article in English | MEDLINE | ID: mdl-37099353

7.

Amyloid-ß immunotherapy for alzheimer disease: Is it now a long shot?

Panza, Francesco; Lozupone, Madia; Seripa, Davide; Imbimbo, Bruno P.

Ann Neurol ; 85(3): 303-315, 2019 03.

Article in English | MEDLINE | ID: mdl-30635926

8.

Time to test antibacterial therapy in Alzheimer's disease.

Panza, Francesco; Lozupone, Madia; Solfrizzi, Vincenzo; Watling, Mark; Imbimbo, Bruno P.

Brain ; 142(10): 2905-2929, 2019 10 01.

Article in English | MEDLINE | ID: mdl-31532495

9.

Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.

Loconte, Valentina; Menozzi, Ilaria; Ferrari, Alberto; Folli, Claudia; Imbimbo, Bruno P; Zanotti, Giuseppe; Berni, Rodolfo.

J Struct Biol ; 208(2): 165-173, 2019 11 01.

Article in English | MEDLINE | ID: mdl-31473362

10.

Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci.

Li, Xiangshun; Lyu, Yanyi; Shen, Jingling; Mu, Yanshuang; Qiang, Lixia; Liu, Li; Araki, Kimi; Imbimbo, Bruno P; Yamamura, Ken-Ichi; Jin, Shoude; Li, Zhenghua.

Lab Invest ; 98(4): 512-524, 2018 04.

Article in English | MEDLINE | ID: mdl-29330472

11.

Should we lower or raise levels of amyloid-ß in the brains of Alzheimer patients?

Imbimbo, Bruno P; Ippati, Stefania; Imbimbo, Camillo; Balducci, Claudia.

Pharmacol Res ; 183: 106390, 2022 09.

Article in English | MEDLINE | ID: mdl-35940397

12.

Emerging drugs to reduce abnormal ß-amyloid protein in Alzheimer's disease patients.

Panza, Francesco; Seripa, Davide; Solfrizzi, Vincenzo; Imbimbo, Bruno P; Lozupone, Madia; Leo, Antonio; Sardone, Rodolfo; Gagliardi, Gaetano; Lofano, Lucia; Creanza, Bianca C; Bisceglia, Paola; Daniele, Antonio; Bellomo, Antonello; Greco, Antonio; Logroscino, Giancarlo.

Expert Opin Emerg Drugs ; 21(4): 377-391, 2016 Dec.

Article in English | MEDLINE | ID: mdl-27678025

13.

Recalibrating the Risk-Benefit Profiles of Lecanemab and Donanemab: Scales, Immunoreactivity, and Changes in Amyloid-ß42.

Espay, Alberto J; Herrup, Karl; Imbimbo, Bruno P; Kepp, Kasper P; Daly, Timothy.

J Alzheimers Dis ; 99(3): 877-881, 2024.

Article in English | MEDLINE | ID: mdl-38701151

14.

A critical appraisal of blood-based biomarkers for Alzheimer's disease.

Lista, Simone; Mapstone, Mark; Caraci, Filippo; Emanuele, Enzo; López-Ortiz, Susana; Martín-Hernández, Juan; Triaca, Viviana; Imbimbo, Camillo; Gabelle, Audrey; Mielke, Michelle M; Nisticò, Robert; Santos-Lozano, Alejandro; Imbimbo, Bruno P.

Ageing Res Rev ; 96: 102290, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38580173

15.

Receptor for advanced glycation end products contributes to postnatal pulmonary development and adult lung maintenance program in mice.

Fineschi, Silvia; De Cunto, Giovanna; Facchinetti, Fabrizio; Civelli, Maurizio; Imbimbo, Bruno P; Carnini, Chiara; Villetti, Gino; Lunghi, Benedetta; Stochino, Stefania; Gibbons, Deena L; Hayday, Adrian; Lungarella, Giuseppe; Cavarra, Eleonora.

Am J Respir Cell Mol Biol ; 48(2): 164-71, 2013 Feb.

Article in English | MEDLINE | ID: mdl-23144333

16.

CHF5074 restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque Tg2576 mice.

Giuliani, Alessandro; Beggiato, Sarah; Baldassarro, Vito A; Mangano, Chiara; Giardino, Luciana; Imbimbo, Bruno P; Antonelli, Tiziana; Calzà, Laura; Ferraro, Luca.

J Neurochem ; 124(5): 613-20, 2013 Mar.

Article in English | MEDLINE | ID: mdl-23278303

17.

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.

Sivilia, Sandra; Lorenzini, Luca; Giuliani, Alessandro; Gusciglio, Marco; Fernandez, Mercedes; Baldassarro, Vito Antonio; Mangano, Chiara; Ferraro, Luca; Pietrini, Vladimiro; Baroc, Maria Francesca; Viscomi, Arturo R; Ottonello, Simone; Villetti, Gino; Imbimbo, Bruno P; Calzà, Laura; Giardino, Luciana.

BMC Neurosci ; 14: 44, 2013 Apr 05.

Article in English | MEDLINE | ID: mdl-23560952

18.

Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects.

Imbimbo, Bruno P; Frigerio, Enrico; Breda, Massimo; Fiorentini, Francesco; Fernandez, Mercedes; Sivilia, Sandra; Giardino, Luciana; Calzà, Laura; Norris, Dottie; Casula, Daniela; Shenouda, Magdy.

Alzheimer Dis Assoc Disord ; 27(3): 278-86, 2013.

Article in English | MEDLINE | ID: mdl-22922591

19.

Frailty syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Aging.

Solfrizzi, Vincenzo; Scafato, Emanuele; Frisardi, Vincenza; Seripa, Davide; Logroscino, Giancarlo; Maggi, Stefania; Imbimbo, Bruno P; Galluzzo, Lucia; Baldereschi, Marzia; Gandin, Claudia; Di Carlo, Antonio; Inzitari, Domenico; Crepaldi, Gaetano; Pilotto, Alberto; Panza, Francesco.

Alzheimers Dement ; 9(2): 113-22, 2013 Mar.

Article in English | MEDLINE | ID: mdl-23245560

20.

Investigational treatments for neurodegenerative diseases caused by inheritance of gene mutations: lessons from recent clinical trials.

Imbimbo, Bruno P; Triaca, Viviana; Imbimbo, Camillo; Nisticò, Robert.

Neural Regen Res ; 18(8): 1679-1683, 2023 Aug.

Article in English | MEDLINE | ID: mdl-36751779

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