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1.
Two distinct classes of cochaperones compete for the EEVD motif in heat shock protein 70 to tune its chaperone activities.
J Biol Chem
; 298(3): 101697, 2022 03.
Article
in English
| MEDLINE | ID: mdl-35148989
2.
Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models.
Pharmacol Res
; 189: 106692, 2023 03.
Article
in English
| MEDLINE | ID: mdl-36773708
3.
Analogs of the Heat Shock Protein 70 Inhibitor MKT-077 Suppress Medullary Thyroid Carcinoma Cells.
Int J Mol Sci
; 23(3)2022 Jan 19.
Article
in English
| MEDLINE | ID: mdl-35162987
4.
Chemical validation of a druggable site on Hsp27/HSPB1 using in silico solvent mapping and biophysical methods.
Bioorg Med Chem
; 34: 115990, 2021 03 15.
Article
in English
| MEDLINE | ID: mdl-33549906
5.
A Conditionally Fluorescent Peptide Reporter of Secondary Structure Modulation.
Chembiochem
; 20(1): 40-45, 2019 01 02.
Article
in English
| MEDLINE | ID: mdl-30137694
6.
Protein-adaptive differential scanning fluorimetry using conformationally responsive dyes.
Nat Biotechnol
; 2024 May 14.
Article
in English
| MEDLINE | ID: mdl-38744946
7.
A missense mutation in the Hspa8 gene encoding heat shock cognate protein 70 causes neuroaxonal dystrophy in rats.
Front Neurosci
; 18: 1263724, 2024.
Article
in English
| MEDLINE | ID: mdl-38384479
8.
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer.
PNAS Nexus
; 2(4): pgad115, 2023 Apr.
Article
in English
| MEDLINE | ID: mdl-37091547
9.
Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry.
bioRxiv
; 2023 Jan 28.
Article
in English
| MEDLINE | ID: mdl-36747624
10.
Multivalent protein-protein interactions are pivotal regulators of eukaryotic Hsp70 complexes.
Cell Stress Chaperones
; 27(4): 397-415, 2022 07.
Article
in English
| MEDLINE | ID: mdl-35670950
11.
High-Throughput Chemical Probing of Full-Length Protein-Protein Interactions.
ACS Comb Sci
; 19(12): 763-769, 2017 12 11.
Article
in English
| MEDLINE | ID: mdl-29112379
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