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1.

Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.

Lee, Seung Cho; Adams, Dexter W; Ipsaro, Jonathan J; Cahn, Jonathan; Lynn, Jason; Kim, Hyun-Soo; Berube, Benjamin; Major, Viktoria; Calarco, Joseph P; LeBlanc, Chantal; Bhattacharjee, Sonali; Ramu, Umamaheswari; Grimanelli, Daniel; Jacob, Yannick; Voigt, Philipp; Joshua-Tor, Leemor; Martienssen, Robert A.

Cell ; 186(19): 4100-4116.e15, 2023 09 14.

Article in English | MEDLINE | ID: mdl-37643610

2.

Manipulating PTPRD function with ectodomain antibodies.

Qian, Zhe; Song, Dongyan; Ipsaro, Jonathan J; Bautista, Carmelita; Joshua-Tor, Leemor; Yeh, Johannes T-H; Tonks, Nicholas K.

Genes Dev ; 37(15-16): 743-759, 2023 08 01.

Article in English | MEDLINE | ID: mdl-37669874

3.

On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme.

Kuhn, Claus-D; Wilusz, Jeremy E; Zheng, Yuxuan; Beal, Peter A; Joshua-Tor, Leemor.

Cell ; 160(4): 644-658, 2015 Feb 12.

Article in English | MEDLINE | ID: mdl-25640237

4.

OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage.

Wu, Xiaoli S; He, Xue-Yan; Ipsaro, Jonathan J; Huang, Yu-Han; Preall, Jonathan B; Ng, David; Shue, Yan Ting; Sage, Julien; Egeblad, Mikala; Joshua-Tor, Leemor; Vakoc, Christopher R.

Nature ; 607(7917): 169-175, 2022 07.

Article in English | MEDLINE | ID: mdl-35576971

5.

The structure of human argonaute-2 in complex with miR-20a.

Elkayam, Elad; Kuhn, Claus-D; Tocilj, Ante; Haase, Astrid D; Greene, Emily M; Hannon, Gregory J; Joshua-Tor, Leemor.

Cell ; 150(1): 100-10, 2012 Jul 06.

Article in English | MEDLINE | ID: mdl-22682761

6.

ELTA: Enzymatic Labeling of Terminal ADP-Ribose.

Ando, Yoshinari; Elkayam, Elad; McPherson, Robert Lyle; Dasovich, Morgan; Cheng, Shang-Jung; Voorneveld, Jim; Filippov, Dmitri V; Ong, Shao-En; Joshua-Tor, Leemor; Leung, Anthony K L.

Mol Cell ; 73(4): 845-856.e5, 2019 02 21.

Article in English | MEDLINE | ID: mdl-30712989

7.

SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23.

Segovia, Danilo; Adams, Dexter W; Hoffman, Nickolas; Safaric Tepes, Polona; Wee, Tse-Luen; Cifani, Paolo; Joshua-Tor, Leemor; Krainer, Adrian R.

Proc Natl Acad Sci U S A ; 121(21): e2322974121, 2024 May 21.

Article in English | MEDLINE | ID: mdl-38743621

8.

FUS Regulates Activity of MicroRNA-Mediated Gene Silencing.

Zhang, Tao; Wu, Yen-Ching; Mullane, Patrick; Ji, Yon Ju; Liu, Honghe; He, Lu; Arora, Amit; Hwang, Ho-Yon; Alessi, Amelia F; Niaki, Amirhossein G; Periz, Goran; Guo, Lin; Wang, Hejia; Elkayam, Elad; Joshua-Tor, Leemor; Myong, Sua; Kim, John K; Shorter, James; Ong, Shao-En; Leung, Anthony K L; Wang, Jiou.

Mol Cell ; 69(5): 787-801.e8, 2018 03 01.

Article in English | MEDLINE | ID: mdl-29499134

9.

Catalytic residues of microRNA Argonautes play a modest role in microRNA star strand destabilization in C. elegans.

Kotagama, Kasuen; Grimme, Acadia L; Braviner, Leah; Yang, Bing; Sakhawala, Rima M; Yu, Guoyun; Benner, Lars Kristian; Joshua-Tor, Leemor; McJunkin, Katherine.

Nucleic Acids Res ; 52(9): 4985-5001, 2024 May 22.

Article in English | MEDLINE | ID: mdl-38471816

10.

Multivalent Recruitment of Human Argonaute by GW182.

Elkayam, Elad; Faehnle, Christopher R; Morales, Marjorie; Sun, Jingchuan; Li, Huilin; Joshua-Tor, Leemor.

Mol Cell ; 67(4): 646-658.e3, 2017 Aug 17.

Article in English | MEDLINE | ID: mdl-28781232

11.

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

Shen, Chen; Ipsaro, Jonathan J; Shi, Junwei; Milazzo, Joseph P; Wang, Eric; Roe, Jae-Seok; Suzuki, Yutaka; Pappin, Darryl J; Joshua-Tor, Leemor; Vakoc, Christopher R.

Mol Cell ; 60(6): 847-59, 2015 Dec 17.

Article in English | MEDLINE | ID: mdl-26626481

12.

PTEN functions by recruitment to cytoplasmic vesicles.

Naguib, Adam; Bencze, Gyula; Cho, Hyejin; Zheng, Wu; Tocilj, Ante; Elkayam, Elad; Faehnle, Christopher R; Jaber, Nadia; Pratt, Christopher P; Chen, Muhan; Zong, Wei-Xing; Marks, Michael S; Joshua-Tor, Leemor; Pappin, Darryl J; Trotman, Lloyd C.

Mol Cell ; 58(2): 255-68, 2015 Apr 16.

Article in English | MEDLINE | ID: mdl-25866245

13.

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations.

Jung, James; Grant, Timothy; Thomas, Dennis R; Diehnelt, Chris W; Grigorieff, Nikolaus; Joshua-Tor, Leemor.

Proc Natl Acad Sci U S A ; 116(26): 12828-12832, 2019 06 25.

Article in English | MEDLINE | ID: mdl-31182604

14.

Structurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference.

Li, Jiahe; Wu, Connie; Wang, Wade; He, Yanpu; Elkayam, Elad; Joshua-Tor, Leemor; Hammond, Paula T.

Proc Natl Acad Sci U S A ; 115(12): E2696-E2705, 2018 03 20.

Article in English | MEDLINE | ID: mdl-29432194

15.

Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.

Faehnle, Christopher R; Walleshauser, Jack; Joshua-Tor, Leemor.

Nature ; 514(7521): 252-256, 2014 Oct 09.

Article in English | MEDLINE | ID: mdl-25119025

16.

The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.

Lavy, Tali; Kumar, P Rajesh; He, Hongzhen; Joshua-Tor, Leemor.

Genes Dev ; 26(3): 294-303, 2012 Feb 01.

Article in English | MEDLINE | ID: mdl-22302941

17.

A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails.

Wilusz, Jeremy E; JnBaptiste, Courtney K; Lu, Laura Y; Kuhn, Claus-D; Joshua-Tor, Leemor; Sharp, Phillip A.

Genes Dev ; 26(21): 2392-407, 2012 Nov 01.

Article in English | MEDLINE | ID: mdl-23073843

18.

siRNA carrying an (E)-vinylphosphonate moiety at the 5Î end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2.

Elkayam, Elad; Parmar, Rubina; Brown, Christopher R; Willoughby, Jennifer L; Theile, Christopher S; Manoharan, Muthiah; Joshua-Tor, Leemor.

Nucleic Acids Res ; 45(6): 3528-3536, 2017 04 07.

Article in English | MEDLINE | ID: mdl-27903888

19.

The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.

Ipsaro, Jonathan J; Haase, Astrid D; Knott, Simon R; Joshua-Tor, Leemor; Hannon, Gregory J.

Nature ; 491(7423): 279-83, 2012 Nov 08.

Article in English | MEDLINE | ID: mdl-23064227

20.

Eukaryotic Argonautes come into focus.

Kuhn, Claus-D; Joshua-Tor, Leemor.

Trends Biochem Sci ; 38(5): 263-71, 2013 May.

Article in English | MEDLINE | ID: mdl-23541793

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