Search | VHL Search Portal

1.

ALT telomeres borrow from meiosis to get moving.

Arnoult, Nausica; Karlseder, Jan.

Cell ; 159(1): 11-12, 2014 Sep 25.

Article in English | MEDLINE | ID: mdl-25259914

2.

Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis.

Nassour, Joe; Aguiar, Lucia Gutierrez; Correia, Adriana; Schmidt, Tobias T; Mainz, Laura; Przetocka, Sara; Haggblom, Candy; Tadepalle, Nimesha; Williams, April; Shokhirev, Maxim N; Akincilar, Semih C; Tergaonkar, Vinay; Shadel, Gerald S; Karlseder, Jan.

Nature ; 614(7949): 767-773, 2023 02.

Article in English | MEDLINE | ID: mdl-36755096

3.

Autophagic cell death restricts chromosomal instability during replicative crisis.

Nassour, Joe; Radford, Robert; Correia, Adriana; Fusté, Javier Miralles; Schoell, Brigitte; Jauch, Anna; Shaw, Reuben J; Karlseder, Jan.

Nature ; 565(7741): 659-663, 2019 01.

Article in English | MEDLINE | ID: mdl-30675059

4.

Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells.

Jones, Celina Y; Williams, Christopher L; Moreno, Sara Priego; Morris, Danna K; Mondello, Chiara; Karlseder, Jan; Bertuch, Alison A.

J Biol Chem ; 299(5): 104665, 2023 05.

Article in English | MEDLINE | ID: mdl-37003504

5.

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

Sfeir, Agnel; Kosiyatrakul, Settapong T; Hockemeyer, Dirk; MacRae, Sheila L; Karlseder, Jan; Schildkraut, Carl L; de Lange, Titia.

Cell ; 138(1): 90-103, 2009 Jul 10.

Article in English | MEDLINE | ID: mdl-19596237

6.

C. elegans telomeres contain G-strand and C-strand overhangs that are bound by distinct proteins.

Raices, Marcela; Verdun, Ramiro E; Compton, Sarah A; Haggblom, Candy I; Griffith, Jack D; Dillin, Andrew; Karlseder, Jan.

Cell ; 132(5): 745-57, 2008 Mar 07.

Article in English | MEDLINE | ID: mdl-18329362

7.

Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN.

Arnoult, Nausica; Correia, Adriana; Ma, Jiao; Merlo, Anna; Garcia-Gomez, Sara; Maric, Marija; Tognetti, Marco; Benner, Christopher W; Boulton, Simon J; Saghatelian, Alan; Karlseder, Jan.

Nature ; 549(7673): 548-552, 2017 09 20.

Article in English | MEDLINE | ID: mdl-28959974

8.

Telomeres: protecting chromosomes against genome instability.

O'Sullivan, Roderick J; Karlseder, Jan.

Nat Rev Mol Cell Biol ; 11(3): 171-81, 2010 Mar.

Article in English | MEDLINE | ID: mdl-20125188

9.

Modern genome editing meets telomeres: the many functions of TPP1.

Karlseder, Jan.

Genes Dev ; 28(17): 1857-8, 2014 Sep 01.

Article in English | MEDLINE | ID: mdl-25184673

10.

Cell death during crisis is mediated by mitotic telomere deprotection.

Hayashi, Makoto T; Cesare, Anthony J; Rivera, Teresa; Karlseder, Jan.

Nature ; 522(7557): 492-6, 2015 Jun 25.

Article in English | MEDLINE | ID: mdl-26108857

11.

The telomere deprotection response is functionally distinct from the genomic DNA damage response.

Cesare, Anthony J; Hayashi, Makoto T; Crabbe, Laure; Karlseder, Jan.

Mol Cell ; 51(2): 141-55, 2013 Jul 25.

Article in English | MEDLINE | ID: mdl-23850488

12.

Mammalian 5' C-rich telomeric overhangs are a mark of recombination-dependent telomere maintenance.

Oganesian, Liana; Karlseder, Jan.

Mol Cell ; 42(2): 224-36, 2011 Apr 22.

Article in English | MEDLINE | ID: mdl-21504833

13.

TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.

Flynn, Rachel Litman; Centore, Richard C; O'Sullivan, Roderick J; Rai, Rekha; Tse, Alice; Songyang, Zhou; Chang, Sandy; Karlseder, Jan; Zou, Lee.

Nature ; 471(7339): 532-6, 2011 Mar 24.

Article in English | MEDLINE | ID: mdl-21399625

14.

The great unravelling: chromatin as a modulator of the aging process.

O'Sullivan, Roderick J; Karlseder, Jan.

Trends Biochem Sci ; 37(11): 466-76, 2012 Nov.

Article in English | MEDLINE | ID: mdl-22959736

15.

Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans.

Lackner, Daniel H; Raices, Marcela; Maruyama, Hugo; Haggblom, Candy; Karlseder, Jan.

EMBO J ; 31(8): 2024-33, 2012 Apr 18.

Article in English | MEDLINE | ID: mdl-22425786

16.

Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer.

Corpet, Armelle; De Koning, Leanne; Toedling, Joern; Savignoni, Alexia; Berger, Frédérique; Lemaître, Charlène; O'Sullivan, Roderick J; Karlseder, Jan; Barillot, Emmanuel; Asselain, Bernard; Sastre-Garau, Xavier; Almouzni, Geneviève.

EMBO J ; 30(3): 480-93, 2011 Feb 02.

Article in English | MEDLINE | ID: mdl-21179005

17.

The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures.

Barefield, Colleen; Karlseder, Jan.

Nucleic Acids Res ; 40(15): 7358-67, 2012 Aug.

Article in English | MEDLINE | ID: mdl-22576367

18.

Telomeres as hotspots for innate immunity and inflammation.

Nassour, Joe; Przetocka, Sara; Karlseder, Jan.

DNA Repair (Amst) ; 133: 103591, 2024 Jan.

Article in English | MEDLINE | ID: mdl-37951043

19.

High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer.

Schmidt, Tobias T; Tyer, Carly; Rughani, Preeyesh; Haggblom, Candy; Jones, Jeffrey R; Dai, Xiaoguang; Frazer, Kelly A; Gage, Fred H; Juul, Sissel; Hickey, Scott; Karlseder, Jan.

Nat Commun ; 15(1): 5149, 2024 Jun 18.

Article in English | MEDLINE | ID: mdl-38890299

20.

Replication and protection of telomeres.

Verdun, Ramiro E; Karlseder, Jan.

Nature ; 447(7147): 924-31, 2007 Jun 21.

Article in English | MEDLINE | ID: mdl-17581575

VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: