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1.
Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11.
Proc Natl Acad Sci U S A
; 119(28): e2122840119, 2022 07 12.
Article
in English
| MEDLINE | ID: mdl-35867762
2.
Loss of FLCN inhibits canonical WNT signaling via TFE3.
Hum Mol Genet
; 28(19): 3270-3281, 2019 10 01.
Article
in English
| MEDLINE | ID: mdl-31272105
3.
Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma.
PLoS Genet
; 14(9): e1007679, 2018 09.
Article
in English
| MEDLINE | ID: mdl-30256787
4.
Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma.
Proc Natl Acad Sci U S A
; 115(27): E6274-E6282, 2018 07 03.
Article
in English
| MEDLINE | ID: mdl-29891694
5.
TSC2 regulates microRNA biogenesis via mTORC1 and GSK3ß.
Hum Mol Genet
; 27(9): 1654-1663, 2018 05 01.
Article
in English
| MEDLINE | ID: mdl-29509898
6.
New Developments in the Pathogenesis of Pulmonary Cysts in Birt-Hogg-Dubé Syndrome.
Semin Respir Crit Care Med
; 41(2): 247-255, 2020 04.
Article
in English
| MEDLINE | ID: mdl-32279295
7.
Mechanisms of pulmonary cyst pathogenesis in Birt-Hogg-Dube syndrome: The stretch hypothesis.
Semin Cell Dev Biol
; 52: 47-52, 2016 Apr.
Article
in English
| MEDLINE | ID: mdl-26877139
8.
Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis.
Am J Respir Cell Mol Biol
; 53(1): 33-41, 2015 Jul.
Article
in English
| MEDLINE | ID: mdl-25780943
9.
TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
Nat Commun
; 15(1): 406, 2024 Jan 09.
Article
in English
| MEDLINE | ID: mdl-38195686
10.
mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion.
Nat Commun
; 14(1): 1214, 2023 03 03.
Article
in English
| MEDLINE | ID: mdl-36869048
11.
TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation.
Mol Cancer Res
; 19(8): 1389-1397, 2021 08.
Article
in English
| MEDLINE | ID: mdl-33888601
12.
TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism.
Nat Commun
; 12(1): 4245, 2021 07 12.
Article
in English
| MEDLINE | ID: mdl-34253722
13.
Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R.
Oncotarget
; 8(24): 38099-38112, 2017 Jun 13.
Article
in English
| MEDLINE | ID: mdl-28498820
14.
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Cancer Res
; 77(12): 3255-3267, 2017 06 15.
Article
in English
| MEDLINE | ID: mdl-28512249
15.
High-throughput drug screen identifies chelerythrine as a selective inducer of death in a TSC2-null setting.
Mol Cancer Res
; 13(1): 50-62, 2015 Jan.
Article
in English
| MEDLINE | ID: mdl-25185584
16.
Correction: p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Cancer Res
; 80(23): 5424, 2020 Dec 01.
Article
in English
| MEDLINE | ID: mdl-33268556
17.
Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells.
Physiol Rep
; 2(8)2014 Aug 01.
Article
in English
| MEDLINE | ID: mdl-25121506
18.
Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
PLoS One
; 7(11): e47842, 2012.
Article
in English
| MEDLINE | ID: mdl-23139756
19.
The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development.
J Clin Invest
; 120(1): 93-102, 2010 Jan.
Article
in English
| MEDLINE | ID: mdl-20038815
20.
The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe.
J Biol Chem
; 282(34): 24583-90, 2007 Aug 24.
Article
in English
| MEDLINE | ID: mdl-17556368
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