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1.

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine.

Goel, Rishi R; Painter, Mark M; Lundgreen, Kendall A; Apostolidis, Sokratis A; Baxter, Amy E; Giles, Josephine R; Mathew, Divij; Pattekar, Ajinkya; Reynaldi, Arnold; Khoury, David S; Gouma, Sigrid; Hicks, Philip; Dysinger, Sarah; Hicks, Amanda; Sharma, Harsh; Herring, Sarah; Korte, Scott; Kc, Wumesh; Oldridge, Derek A; Erickson, Rachel I; Weirick, Madison E; McAllister, Christopher M; Awofolaju, Moses; Tanenbaum, Nicole; Dougherty, Jeanette; Long, Sherea; D'Andrea, Kurt; Hamilton, Jacob T; McLaughlin, Maura; Williams, Justine C; Adamski, Sharon; Kuthuru, Oliva; Drapeau, Elizabeth M; Davenport, Miles P; Hensley, Scott E; Bates, Paul; Greenplate, Allison R; Wherry, E John.

Cell ; 185(11): 1875-1887.e8, 2022 05 26.

Article in English | MEDLINE | ID: mdl-35523182

2.

Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.

Zhang, Wuji; Kedzierski, Lukasz; Chua, Brendon Y; Mayo, Mark; Lonzi, Claire; Rigas, Vanessa; Middleton, Bianca F; McQuilten, Hayley A; Rowntree, Louise C; Allen, Lilith F; Purcell, Ruth A; Tan, Hyon-Xhi; Petersen, Jan; Chaurasia, Priyanka; Mordant, Francesca; Pogorelyy, Mikhail V; Minervina, Anastasia A; Crawford, Jeremy Chase; Perkins, Griffith B; Zhang, Eva; Gras, Stephanie; Clemens, E Bridie; Juno, Jennifer A; Audsley, Jennifer; Khoury, David S; Holmes, Natasha E; Thevarajan, Irani; Subbarao, Kanta; Krammer, Florian; Cheng, Allen C; Davenport, Miles P; Grubor-Bauk, Branka; Coates, P Toby; Christensen, Britt; Thomas, Paul G; Wheatley, Adam K; Kent, Stephen J; Rossjohn, Jamie; Chung, Amy W; Boffa, John; Miller, Adrian; Lynar, Sarah; Nelson, Jane; Nguyen, Thi H O; Davies, Jane; Kedzierska, Katherine.

Nat Immunol ; 24(6): 966-978, 2023 06.

Article in English | MEDLINE | ID: mdl-37248417

3.

Transcriptome dynamics of CD4⁺ T cells during malaria maps gradual transit from effector to memory.

Soon, Megan S F; Lee, Hyun Jae; Engel, Jessica A; Straube, Jasmin; Thomas, Bryce S; Pernold, Clara P S; Clarke, Lachlan S; Laohamonthonkul, Pawat; Haldar, Rohit N; Williams, Cameron G; Lansink, Lianne I M; Moreira, Marcela L; Bramhall, Michael; Koufariotis, Lambros T; Wood, Scott; Chen, Xi; James, Kylie R; Lönnberg, Tapio; Lane, Steven W; Belz, Gabrielle T; Engwerda, Christian R; Khoury, David S; Davenport, Miles P; Svensson, Valentine; Teichmann, Sarah A; Haque, Ashraful.

Nat Immunol ; 21(12): 1597-1610, 2020 12.

Article in English | MEDLINE | ID: mdl-33046889

4.

The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants.

Koutsakos, Marios; Lee, Wen Shi; Reynaldi, Arnold; Tan, Hyon-Xhi; Gare, Grace; Kinsella, Paul; Liew, Kwee Chin; Taiaroa, George; Williamson, Deborah A; Kent, Helen E; Stadler, Eva; Cromer, Deborah; Khoury, David S; Wheatley, Adam K; Juno, Jennifer A; Davenport, Miles P; Kent, Stephen J.

Immunity ; 55(7): 1316-1326.e4, 2022 07 12.

Article in English | MEDLINE | ID: mdl-35690062

5.

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization.

Cele, Sandile; Jackson, Laurelle; Khoury, David S; Khan, Khadija; Moyo-Gwete, Thandeka; Tegally, Houriiyah; San, James Emmanuel; Cromer, Deborah; Scheepers, Cathrine; Amoako, Daniel G; Karim, Farina; Bernstein, Mallory; Lustig, Gila; Archary, Derseree; Smith, Muneerah; Ganga, Yashica; Jule, Zesuliwe; Reedoy, Kajal; Hwa, Shi-Hsia; Giandhari, Jennifer; Blackburn, Jonathan M; Gosnell, Bernadett I; Abdool Karim, Salim S; Hanekom, Willem; von Gottberg, Anne; Bhiman, Jinal N; Lessells, Richard J; Moosa, Mahomed-Yunus S; Davenport, Miles P; de Oliveira, Tulio; Moore, Penny L; Sigal, Alex.

Nature ; 602(7898): 654-656, 2022 02.

Article in English | MEDLINE | ID: mdl-35016196

6.

Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection.

Khoury, David S; Schlub, Timothy E; Cromer, Deborah; Steain, Megan; Fong, Youyi; Gilbert, Peter B; Subbarao, Kanta; Triccas, James A; Kent, Stephen J; Davenport, Miles P.

Emerg Infect Dis ; 29(2): 381-388, 2023 02.

Article in English | MEDLINE | ID: mdl-36692375

7.

Long-term vaccination strategies to mitigate the impact of SARS-CoV-2 transmission: A modelling study.

Hogan, Alexandra B; Wu, Sean L; Toor, Jaspreet; Olivera Mesa, Daniela; Doohan, Patrick; Watson, Oliver J; Winskill, Peter; Charles, Giovanni; Barnsley, Gregory; Riley, Eleanor M; Khoury, David S; Ferguson, Neil M; Ghani, Azra C.

PLoS Med ; 20(11): e1004195, 2023 Nov.

Article in English | MEDLINE | ID: mdl-38016000

8.

Evidence for exposure dependent carriage of malaria parasites across the dry season: modelling analysis of longitudinal data.

Stadler, Eva; Cromer, Deborah; Ogunlade, Samson; Ongoiba, Aissata; Doumbo, Safiatou; Kayentao, Kassoum; Traore, Boubacar; Crompton, Peter D; Portugal, Silvia; Davenport, Miles P; Khoury, David S.

Malar J ; 22(1): 42, 2023 Feb 03.

Article in English | MEDLINE | ID: mdl-36737743

9.

Relating In Vitro Neutralization Level and Protection in the CVnCoV (CUREVAC) Trial.

Cromer, Deborah; Reynaldi, Arnold; Steain, Megan; Triccas, James A; Davenport, Miles P; Khoury, David S.

Clin Infect Dis ; 75(1): e878-e879, 2022 08 24.

Article in English | MEDLINE | ID: mdl-35100611

10.

Parasite Viability as a Measure of In Vivo Drug Activity in Preclinical and Early Clinical Antimalarial Drug Assessment.

Radohery, Georges F R; Walz, Annabelle; Gumpp, Christin; Cherkaoui-Rbati, Mohammed H; Gobeau, Nathalie; Gower, Jeremy; Davenport, Miles P; Rottmann, Matthias; McCarthy, James S; Möhrle, Jörg J; Rebelo, Maria; Demarta-Gatsi, Claudia; Khoury, David S.

Antimicrob Agents Chemother ; 66(7): e0011422, 2022 07 19.

Article in English | MEDLINE | ID: mdl-35727057

11.

Similarly efficacious anti-malarial drugs SJ733 and pyronaridine differ in their ability to remove circulating parasites in mice.

SheelaNair, Arya; Romanczuk, Aleksandra S; Aogo, Rosemary A; Haldar, Rohit Nemai; Lansink, Lianne I M; Cromer, Deborah; Salinas, Yandira G; Guy, R Kiplin; McCarthy, James S; Davenport, Miles P; Haque, Ashraful; Khoury, David S.

Malar J ; 21(1): 49, 2022 Feb 16.

Article in English | MEDLINE | ID: mdl-35172826

12.

Within-host modeling of blood-stage malaria.

Khoury, David S; Aogo, Rosemary; Randriafanomezantsoa-Radohery, Georges; McCaw, James M; Simpson, Julie A; McCarthy, James S; Haque, Ashraful; Cromer, Deborah; Davenport, Miles P.

Immunol Rev ; 285(1): 168-193, 2018 09.

Article in English | MEDLINE | ID: mdl-30129195

13.

Parasite Viability as a Superior Measure of Antimalarial Drug Activity in Humans.

Rebelo, Maria; Pawliw, Rebecca; Gower, Jeremy; Webb, Lachlan; Mitchell, Hayley; Pava, Zuleima; Watts, Rebecca E; Davenport, Miles P; McCarthy, James S; Khoury, David S.

J Infect Dis ; 223(12): 2154-2163, 2021 06 15.

Article in English | MEDLINE | ID: mdl-33119072

14.

Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.

Akter, Jasmin; Khoury, David S; Aogo, Rosemary; Lansink, Lianne I M; SheelaNair, Arya; Thomas, Bryce S; Laohamonthonkul, Pawat; Pernold, Clara P S; Dixon, Matthew W A; Soon, Megan S F; Fogg, Lily G; Engel, Jessica A; Elliott, Trish; Sebina, Ismail; James, Kylie R; Cromer, Deborah; Davenport, Miles P; Haque, Ashraful.

PLoS Pathog ; 15(2): e1007599, 2019 02.

Article in English | MEDLINE | ID: mdl-30811498

15.

Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection.

Khoury, David S; Cromer, Deborah; Akter, Jasmin; Sebina, Ismail; Elliott, Trish; Thomas, Bryce S; Soon, Megan S F; James, Kylie R; Best, Shannon E; Haque, Ashraful; Davenport, Miles P.

Proc Natl Acad Sci U S A ; 114(29): 7701-7706, 2017 07 18.

Article in English | MEDLINE | ID: mdl-28673996

16.

In Silico Investigation of the Decline in Clinical Efficacy of Artemisinin Combination Therapies Due to Increasing Artemisinin and Partner Drug Resistance.

Zaloumis, Sophie G; Cao, Pengxing; Dini, Saber; Davenport, Miles P; Cromer, Deborah; Khoury, David S; Fowkes, Freya J I; McCaw, James M; Simpson, Julie A.

Antimicrob Agents Chemother ; 62(12)2018 12.

Article in English | MEDLINE | ID: mdl-30249691

17.

A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection.

Cao, Pengxing; Klonis, Nectarios; Zaloumis, Sophie; Khoury, David S; Cromer, Deborah; Davenport, Miles P; Tilley, Leann; Simpson, Julie A; McCaw, James M.

J Theor Biol ; 430: 117-127, 2017 10 07.

Article in English | MEDLINE | ID: mdl-28728995

18.

Reply to White and Watson.

Rebelo, Maria; McCarthy, James S; Khoury, David S.

J Infect Dis ; 224(4): 739-740, 2021 08 16.

Article in English | MEDLINE | ID: mdl-34398240

19.

Defining the Effectiveness of Antimalarial Chemotherapy: Investigation of the Lag in Parasite Clearance Following Drug Administration.

Khoury, David S; Cromer, Deborah; Möhrle, Jörg J; McCarthy, James S; Davenport, Miles P.

J Infect Dis ; 214(5): 753-61, 2016 09 01.

Article in English | MEDLINE | ID: mdl-27252475

20.

Effect of mature blood-stage Plasmodium parasite sequestration on pathogen biomass in mathematical and in vivo models of malaria.

Khoury, David S; Cromer, Deborah; Best, Shannon E; James, Kylie R; Kim, Peter S; Engwerda, Christian R; Haque, Ashraful; Davenport, Miles P.

Infect Immun ; 82(1): 212-20, 2014 Jan.

Article in English | MEDLINE | ID: mdl-24144725

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