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1.

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression.

Peñuelas-Haro, Irene; Espinosa-Sotelo, Rut; Crosas-Molist, Eva; Herranz-Itúrbide, Macarena; Caballero-Díaz, Daniel; Alay, Ania; Solé, Xavier; Ramos, Emilio; Serrano, Teresa; Martínez-Chantar, María L; Knaus, Ulla G; Cuezva, José M; Zorzano, Antonio; Bertran, Esther; Fabregat, Isabel.

Hepatology ; 78(2): 416-433, 2023 08 01.

Article in English | MEDLINE | ID: mdl-35920301

2.

Gremlin 1 is required for macrophage M2 polarization.

Mthunzi, Liberty; Rowan, Simon C; Kostyunina, Daria S; Baugh, John A; Knaus, Ulla G; McLoughlin, Paul.

Am J Physiol Lung Cell Mol Physiol ; 325(2): L270-L276, 2023 08 01.

Article in English | MEDLINE | ID: mdl-37401390

3.

Oxidants in Physiological Processes.

Knaus, Ulla G.

Handb Exp Pharmacol ; 264: 27-47, 2021.

Article in English | MEDLINE | ID: mdl-32767144

4.

Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly.

O'Neill, Sharon; Mathis, Magalie; Kovacic, Lidija; Zhang, Suisheng; Reinhardt, Jürgen; Scholz, Dimitri; Schopfer, Ulrich; Bouhelal, Rochdi; Knaus, Ulla G.

J Biol Chem ; 293(23): 8750-8760, 2018 06 08.

Article in English | MEDLINE | ID: mdl-29674345

5.

House dust mite-treated PAR2 over-expressor mouse: A novel model of atopic dermatitis.

Smith, Leila; Gatault, Solene; Casals-Diaz, Laura; Kelly, Pamela A; Camerer, Eric; Métais, Charles; Knaus, Ulla G; Eissner, Günther; Steinhoff, Martin.

Exp Dermatol ; 28(11): 1298-1308, 2019 11.

Article in English | MEDLINE | ID: mdl-31487753

6.

NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA.

Alvarez, Luis A; Kovacic, Lidija; Rodríguez, Javier; Gosemann, Jan-Hendrik; Kubica, Malgorzata; Pircalabioru, Gratiela G; Friedmacher, Florian; Cean, Ada; Ghise, Alina; Sarandan, Mihai B; Puri, Prem; Daff, Simon; Plettner, Erika; von Kriegsheim, Alex; Bourke, Billy; Knaus, Ulla G.

Proc Natl Acad Sci U S A ; 113(37): 10406-11, 2016 09 13.

Article in English | MEDLINE | ID: mdl-27562167

7.

Cellular ROS imaging with hydro-Cy3 dye is strongly influenced by mitochondrial membrane potential.

Zhdanov, Alexander V; Aviello, Gabriella; Knaus, Ulla G; Papkovsky, Dmitri B.

Biochim Biophys Acta Gen Subj ; 1861(2): 198-204, 2017 Feb.

Article in English | MEDLINE | ID: mdl-27818165

8.

RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness.

Jennings, Richard T; Strengert, Monika; Hayes, Patti; El-Benna, Jamel; Brakebusch, Cord; Kubica, Malgorzata; Knaus, Ulla G.

Blood ; 123(23): 3635-45, 2014 Jun 05.

Article in English | MEDLINE | ID: mdl-24782506

9.

Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.

Königs, Volker; Jennings, Richard; Vogl, Thomas; Horsthemke, Markus; Bachg, Anne C; Xu, Yan; Grobe, Kay; Brakebusch, Cord; Schwab, Albrecht; Bähler, Martin; Knaus, Ulla G; Hanley, Peter J.

J Biol Chem ; 289(44): 30772-30784, 2014 Oct 31.

Article in English | MEDLINE | ID: mdl-25213860

10.

Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax.

Ghosh, Chandra C; Mukherjee, Aditi; David, Sascha; Knaus, Ulla G; Stearns-Kurosawa, Deborah J; Kurosawa, Shinichiro; Parikh, Samir M.

Proc Natl Acad Sci U S A ; 109(25): 10024-9, 2012 Jun 19.

Article in English | MEDLINE | ID: mdl-22665799

11.

Characterization of intestinal O-glycome in reactive oxygen species deficiency.

Saldova, Radka; Thomsson, Kristina A; Wilkinson, Hayden; Chatterjee, Maitrayee; Singh, Ashish K; Karlsson, Niclas G; Knaus, Ulla G.

PLoS One ; 19(3): e0297292, 2024.

Article in English | MEDLINE | ID: mdl-38483964

12.

Constitutive NADPH oxidase 4 activity resides in the composition of the B-loop and the penultimate C terminus.

von Löhneysen, Katharina; Noack, Deborah; Hayes, Patti; Friedman, Jeffrey S; Knaus, Ulla G.

J Biol Chem ; 287(12): 8737-45, 2012 Mar 16.

Article in English | MEDLINE | ID: mdl-22277655

13.

First Identification of Biallelic Inherited DUOX2 Inactivating Mutations as a Cause of Very Early Onset Inflammatory Bowel Disease.

Parlato, Marianna; Charbit-Henrion, Fabienne; Hayes, Patti; Tiberti, Antonio; Aloi, Marina; Cucchiara, Salvatore; Bègue, Bernadette; Bras, Marc; Pouliet, Aurore; Rakotobe, Sabine; Ruemmele, Frank; Knaus, Ulla G; Cerf-Bensussan, Nadine.

Gastroenterology ; 153(2): 609-611.e3, 2017 08.

Article in English | MEDLINE | ID: mdl-28683258

14.

VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity.

Ward, Josie; Zhang, Suisheng; Sikora, Adam; Michalski, Radoslaw; Yin, Yuting; D'Alessio, Aurora; McLoughlin, Rachel M; Jaquet, Vincent; Fieschi, Franck; Knaus, Ulla G.

Redox Biol ; 67: 102905, 2023 11.

Article in English | MEDLINE | ID: mdl-37820403

15.

Case report: Neonatal-onset inflammatory bowel disease due to novel compound heterozygous mutations in DUOX2.

Finocchi, Andrea; Pacillo, Lucia; Chiriaco, Maria; Di Matteo, Gigliola; Francalanci, Paola; Angelino, Giulia; Caldaro, Tamara; Rivalta, Beatrice; O'Mara, Maurice; Zhang, Suisheng; Lepri, Francesca Romana; Novelli, Antonio; De Angelis, Paola; Knaus, Ulla G; Rea, Francesca.

Front Genet ; 14: 1276697, 2023.

Article in English | MEDLINE | ID: mdl-38075699

16.

Bioluminescence-Based Complementation Assay to Correlate Conformational Changes in Membrane-Bound Complexes with Enzymatic Function.

O'Neill, Sharon; Knaus, Ulla G.

Methods Mol Biol ; 2525: 123-137, 2022.

Article in English | MEDLINE | ID: mdl-35836064

17.

Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice.

Englert, Maximilian; Aurbach, Katja; Becker, Isabelle C; Gerber, Annika; Heib, Tobias; Wackerbarth, Lou M; Kusch, Charly; Mott, Kristina; Araujo, Gabriel H M; Baig, Ayesha A; Dütting, Sebastian; Knaus, Ulla G; Stigloher, Christian; Schulze, Harald; Nieswandt, Bernhard; Pleines, Irina; Nagy, Zoltan.

Blood Adv ; 6(17): 5184-5197, 2022 09 13.

Article in English | MEDLINE | ID: mdl-35819450

18.

RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-kappa B.

Manukyan, Maria; Nalbant, Perihan; Luxen, Sylvia; Hahn, Klaus M; Knaus, Ulla G.

J Immunol ; 182(6): 3522-9, 2009 Mar 15.

Article in English | MEDLINE | ID: mdl-19265130

19.

Raising the 'Good' Oxidants for Immune Protection.

Dumas, Alexia; Knaus, Ulla G.

Front Immunol ; 12: 698042, 2021.

Article in English | MEDLINE | ID: mdl-34149739

20.

NADPH oxidase 4 is protective and not fibrogenic in intestinal inflammation.

Stenke, Emily; Aviello, Gabriella; Singh, Ashish; Martin, Sean; Winter, Des; Sweeney, Brian; McDermott, Michael; Bourke, Billy; Hussey, Seamus; Knaus, Ulla G.

Redox Biol ; 37: 101752, 2020 10.

Article in English | MEDLINE | ID: mdl-33059312

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