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1.

Human organoids: New strategies and methods for analyzing human development and disease.

Corsini, Nina S; Knoblich, Juergen A.

Cell ; 185(15): 2756-2769, 2022 07 21.

Article in English | MEDLINE | ID: mdl-35868278

2.

Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis.

Bonnay, François; Veloso, Ana; Steinmann, Victoria; Köcher, Thomas; Abdusselamoglu, Merve Deniz; Bajaj, Sunanjay; Rivelles, Elisa; Landskron, Lisa; Esterbauer, Harald; Zinzen, Robert P; Knoblich, Juergen A.

Cell ; 182(6): 1490-1507.e19, 2020 09 17.

Article in English | MEDLINE | ID: mdl-32916131

3.

Human organoids: model systems for human biology and medicine.

Kim, Jihoon; Koo, Bon-Kyoung; Knoblich, Juergen A.

Nat Rev Mol Cell Biol ; 21(10): 571-584, 2020 10.

Article in English | MEDLINE | ID: mdl-32636524

4.

Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells.

Homem, Catarina C F; Steinmann, Victoria; Burkard, Thomas R; Jais, Alexander; Esterbauer, Harald; Knoblich, Juergen A.

Cell ; 158(4): 874-888, 2014 Aug 14.

Article in English | MEDLINE | ID: mdl-25126791

5.

SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells.

Eroglu, Elif; Burkard, Thomas R; Jiang, Yanrui; Saini, Nidhi; Homem, Catarina C F; Reichert, Heinrich; Knoblich, Juergen A.

Cell ; 156(6): 1259-1273, 2014 Mar 13.

Article in English | MEDLINE | ID: mdl-24630726

6.

Single-cell brain organoid screening identifies developmental defects in autism.

Li, Chong; Fleck, Jonas Simon; Martins-Costa, Catarina; Burkard, Thomas R; Themann, Jan; Stuempflen, Marlene; Peer, Angela Maria; Vertesy, Ábel; Littleboy, Jamie B; Esk, Christopher; Elling, Ulrich; Kasprian, Gregor; Corsini, Nina S; Treutlein, Barbara; Knoblich, Juergen A.

Nature ; 621(7978): 373-380, 2023 Sep.

Article in English | MEDLINE | ID: mdl-37704762

7.

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets.

Vértesy, Ábel; Eichmüller, Oliver L; Naas, Julia; Novatchkova, Maria; Esk, Christopher; Balmaña, Meritxell; Ladstaetter, Sabrina; Bock, Christoph; von Haeseler, Arndt; Knoblich, Juergen A.

EMBO J ; 41(17): e111118, 2022 09 01.

Article in English | MEDLINE | ID: mdl-35919947

8.

Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration.

Bajaj, Sunanjay; Bagley, Joshua A; Sommer, Christoph; Vertesy, Abel; Nagumo Wong, Sakurako; Krenn, Veronica; Lévi-Strauss, Julie; Knoblich, Juergen A.

EMBO J ; 40(23): e108714, 2021 12 01.

Article in English | MEDLINE | ID: mdl-34661293

9.

Human blood vessel organoids as a model of diabetic vasculopathy.

Wimmer, Reiner A; Leopoldi, Alexandra; Aichinger, Martin; Wick, Nikolaus; Hantusch, Brigitte; Novatchkova, Maria; Taubenschmid, Jasmin; Hämmerle, Monika; Esk, Christopher; Bagley, Joshua A; Lindenhofer, Dominik; Chen, Guibin; Boehm, Manfred; Agu, Chukwuma A; Yang, Fengtang; Fu, Beiyuan; Zuber, Johannes; Knoblich, Juergen A; Kerjaschki, Dontscho; Penninger, Josef M.

Nature ; 565(7740): 505-510, 2019 01.

Article in English | MEDLINE | ID: mdl-30651639

10.

Fly stem cell research gets infectious.

Conder, Ryan; Knoblich, Juergen A.

Cell ; 137(7): 1185-7, 2009 Jun 26.

Article in English | MEDLINE | ID: mdl-19563751

11.

The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors.

Schwamborn, Jens C; Berezikov, Eugene; Knoblich, Juergen A.

Cell ; 136(5): 913-25, 2009 Mar 06.

Article in English | MEDLINE | ID: mdl-19269368

12.

Author Correction: Single-cell brain organoid screening identifies developmental defects in autism.

Li, Chong; Fleck, Jonas Simon; Martins-Costa, Catarina; Burkard, Thomas R; Themann, Jan; Stuempflen, Marlene; Peer, Angela Maria; Vertesy, Ábel; Littleboy, Jamie B; Esk, Christopher; Elling, Ulrich; Kasprian, Gregor; Corsini, Nina S; Treutlein, Barbara; Knoblich, Juergen A.

Nature ; 623(7989): E20, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37964131

13.

Mechanisms of asymmetric stem cell division.

Knoblich, Juergen A.

Cell ; 132(4): 583-97, 2008 Feb 22.

Article in English | MEDLINE | ID: mdl-18295577

14.

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.

Wirtz-Peitz, Frederik; Nishimura, Takashi; Knoblich, Juergen A.

Cell ; 135(1): 161-73, 2008 Oct 03.

Article in English | MEDLINE | ID: mdl-18854163

15.

Asymmetric cell division: recent developments and their implications for tumour biology.

Knoblich, Juergen A.

Nat Rev Mol Cell Biol ; 11(12): 849-60, 2010 Dec.

Article in English | MEDLINE | ID: mdl-21102610

16.

Self-organized developmental patterning and differentiation in cerebral organoids.

Renner, Magdalena; Lancaster, Madeline A; Bian, Shan; Choi, Heejin; Ku, Taeyun; Peer, Angela; Chung, Kwanghun; Knoblich, Juergen A.

EMBO J ; 36(10): 1316-1329, 2017 05 15.

Article in English | MEDLINE | ID: mdl-28283582

17.

MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development.

Fededa, Juan Pablo; Esk, Christopher; Mierzwa, Beata; Stanyte, Rugile; Yuan, Shuiqiao; Zheng, Huili; Ebnet, Klaus; Yan, Wei; Knoblich, Juergen A; Gerlich, Daniel W.

EMBO J ; 35(22): 2386-2398, 2016 11 15.

Article in English | MEDLINE | ID: mdl-27707753

18.

The hope and the hype of organoid research.

Huch, Meritxell; Knoblich, Juergen A; Lutolf, Matthias P; Martinez-Arias, Alfonso.

Development ; 144(6): 938-941, 2017 03 15.

Article in English | MEDLINE | ID: mdl-28292837

19.

The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells.

Abramczuk, Monika K; Burkard, Thomas R; Rolland, Vivien; Steinmann, Victoria; Duchek, Peter; Jiang, Yanrui; Wissel, Sebastian; Reichert, Heinrich; Knoblich, Juergen A.

Development ; 144(21): 3932-3945, 2017 11 01.

Article in English | MEDLINE | ID: mdl-28935704

20.

Fused cerebral organoids model interactions between brain regions.

Bagley, Joshua A; Reumann, Daniel; Bian, Shan; Lévi-Strauss, Julie; Knoblich, Juergen A.

Nat Methods ; 14(7): 743-751, 2017 Jul.

Article in English | MEDLINE | ID: mdl-28504681

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