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1.

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.

Kakiuchi, Nobuyuki; Yoshida, Kenichi; Uchino, Motoi; Kihara, Takako; Akaki, Kotaro; Inoue, Yoshikage; Kawada, Kenji; Nagayama, Satoshi; Yokoyama, Akira; Yamamoto, Shuji; Matsuura, Minoru; Horimatsu, Takahiro; Hirano, Tomonori; Goto, Norihiro; Takeuchi, Yasuhide; Ochi, Yotaro; Shiozawa, Yusuke; Kogure, Yasunori; Watatani, Yosaku; Fujii, Yoichi; Kim, Soo Ki; Kon, Ayana; Kataoka, Keisuke; Yoshizato, Tetsuichi; Nakagawa, Masahiro M; Yoda, Akinori; Nanya, Yasuhito; Makishima, Hideki; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Sanada, Masashi; Sugihara, Eiji; Sato, Taka-Aki; Maruyama, Takashi; Miyoshi, Hiroyuki; Taketo, Makoto Mark; Oishi, Jun; Inagaki, Ryosaku; Ueda, Yutaka; Okamoto, Shinya; Okajima, Hideaki; Sakai, Yoshiharu; Sakurai, Takaki; Haga, Hironori; Hirota, Seiichi; Ikeuchi, Hiroki; Nakase, Hiroshi; Marusawa, Hiroyuki; Chiba, Tsutomu.

Nature ; 577(7789): 260-265, 2020 01.

Article in English | MEDLINE | ID: mdl-31853061

2.

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.

Makishima, Hideki; Saiki, Ryunosuke; Nannya, Yasuhito; Korotev, Sophia; Gurnari, Carmelo; Takeda, June; Momozawa, Yukihide; Best, Steve; Krishnamurthy, Pramila; Yoshizato, Tetsuichi; Atsuta, Yoshiko; Shiozawa, Yusuke; Iijima-Yamashita, Yuka; Yoshida, Kenichi; Shiraishi, Yuichi; Nagata, Yasunobu; Kakiuchi, Nobuyuki; Onizuka, Makoto; Chiba, Kenichi; Tanaka, Hiroko; Kon, Ayana; Ochi, Yotaro; Nakagawa, Masahiro M; Okuda, Rurika; Mori, Takuto; Yoda, Akinori; Itonaga, Hidehiro; Miyazaki, Yasushi; Sanada, Masashi; Ishikawa, Takayuki; Chiba, Shigeru; Tsurumi, Hisashi; Kasahara, Senji; Müller-Tidow, Carsten; Takaori-Kondo, Akifumi; Ohyashiki, Kazuma; Kiguchi, Toru; Matsuda, Fumihiko; Jansen, Joop H; Polprasert, Chantana; Blombery, Piers; Kamatani, Yoichiro; Miyano, Satoru; Malcovati, Luca; Haferlach, Torsten; Kubo, Michiaki; Cazzola, Mario; Kulasekararaj, Austin G; Godley, Lucy A; Maciejewski, Jaroslaw P.

Blood ; 141(5): 534-549, 2023 02 02.

Article in English | MEDLINE | ID: mdl-36322930

3.

Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice.

Kon, Ayana; Yamazaki, Satoshi; Nannya, Yasuhito; Kataoka, Keisuke; Ota, Yasunori; Nakagawa, Masahiro Marshall; Yoshida, Kenichi; Shiozawa, Yusuke; Morita, Maiko; Yoshizato, Tetsuichi; Sanada, Masashi; Nakayama, Manabu; Koseki, Haruhiko; Nakauchi, Hiromitsu; Ogawa, Seishi.

Blood ; 131(6): 621-635, 2018 02 08.

Article in English | MEDLINE | ID: mdl-29146882

4.

[Clonal evolution of myeloid malignancies].

Kon, Ayana.

Rinsho Ketsueki ; 61(9): 1120-1129, 2020.

Article in Japanese | MEDLINE | ID: mdl-33162507

5.

[Clonal evolution of myelodysplastic syndromes].

Kon, Ayana.

Rinsho Ketsueki ; 61(4): 358-367, 2020.

Article in Japanese | MEDLINE | ID: mdl-32378581

6.

Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia.

Yoshizato, Tetsuichi; Dumitriu, Bogdan; Hosokawa, Kohei; Makishima, Hideki; Yoshida, Kenichi; Townsley, Danielle; Sato-Otsubo, Aiko; Sato, Yusuke; Liu, Delong; Suzuki, Hiromichi; Wu, Colin O; Shiraishi, Yuichi; Clemente, Michael J; Kataoka, Keisuke; Shiozawa, Yusuke; Okuno, Yusuke; Chiba, Kenichi; Tanaka, Hiroko; Nagata, Yasunobu; Katagiri, Takamasa; Kon, Ayana; Sanada, Masashi; Scheinberg, Phillip; Miyano, Satoru; Maciejewski, Jaroslaw P; Nakao, Shinji; Young, Neal S; Ogawa, Seishi.

N Engl J Med ; 373(1): 35-47, 2015 Jul 02.

Article in English | MEDLINE | ID: mdl-26132940

7.

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

Nagata, Yasunobu; Kontani, Kenji; Enami, Terukazu; Kataoka, Keisuke; Ishii, Ryohei; Totoki, Yasushi; Kataoka, Tatsuki R; Hirata, Masahiro; Aoki, Kazuhiro; Nakano, Kazumi; Kitanaka, Akira; Sakata-Yanagimoto, Mamiko; Egami, Sachiko; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Shiozawa, Yusuke; Yoshizato, Tetsuichi; Suzuki, Hiromichi; Kon, Ayana; Yoshida, Kenichi; Sato, Yusuke; Sato-Otsubo, Aiko; Sanada, Masashi; Munakata, Wataru; Nakamura, Hiromi; Hama, Natsuko; Miyano, Satoru; Nureki, Osamu; Shibata, Tatsuhiro; Haga, Hironori; Shimoda, Kazuya; Katada, Toshiaki; Chiba, Shigeru; Watanabe, Toshiki; Ogawa, Seishi.

Blood ; 127(5): 596-604, 2016 Feb 04.

Article in English | MEDLINE | ID: mdl-26574607

8.

Frequent pathway mutations of splicing machinery in myelodysplasia.

Yoshida, Kenichi; Sanada, Masashi; Shiraishi, Yuichi; Nowak, Daniel; Nagata, Yasunobu; Yamamoto, Ryo; Sato, Yusuke; Sato-Otsubo, Aiko; Kon, Ayana; Nagasaki, Masao; Chalkidis, George; Suzuki, Yutaka; Shiosaka, Masashi; Kawahata, Ryoichiro; Yamaguchi, Tomoyuki; Otsu, Makoto; Obara, Naoshi; Sakata-Yanagimoto, Mamiko; Ishiyama, Ken; Mori, Hiraku; Nolte, Florian; Hofmann, Wolf-Karsten; Miyawaki, Shuichi; Sugano, Sumio; Haferlach, Claudia; Koeffler, H Phillip; Shih, Lee-Yung; Haferlach, Torsten; Chiba, Shigeru; Nakauchi, Hiromitsu; Miyano, Satoru; Ogawa, Seishi.

Nature ; 478(7367): 64-9, 2011 Sep 11.

Article in English | MEDLINE | ID: mdl-21909114

9.

BRCC3 mutations in myeloid neoplasms.

Huang, Dayong; Nagata, Yasunobu; Grossmann, Vera; Radivoyevitch, Tomas; Okuno, Yusuke; Nagae, Genta; Hosono, Naoko; Schnittger, Susanne; Sanada, Masashi; Przychodzen, Bartlomiej; Kon, Ayana; Polprasert, Chantana; Shen, Wenyi; Clemente, Michael J; Phillips, James G; Alpermann, Tamara; Yoshida, Kenichi; Nadarajah, Niroshan; Sekeres, Mikkael A; Oakley, Kevin; Nguyen, Nhu; Shiraishi, Yuichi; Shiozawa, Yusuke; Chiba, Kenichi; Tanaka, Hiroko; Koeffler, H Phillip; Klein, Hans-Ulrich; Dugas, Martin; Aburatani, Hiroyuki; Miyano, Satoru; Haferlach, Claudia; Kern, Wolfgang; Haferlach, Torsten; Du, Yang; Ogawa, Seishi; Makishima, Hideki.

Haematologica ; 100(8): 1051-7, 2015 Aug.

Article in English | MEDLINE | ID: mdl-26001790

10.

SETBP1 is dispensable for normal and malignant hematopoiesis.

Tanaka, Atsushi; Nishimura, Koutarou; Saika, Wataru; Kon, Ayana; Koike, Yui; Tatsumi, Hiromi; Takeda, June; Nomura, Masaki; Zang, Weijia; Nakayama, Manabu; Matsuda, Masashi; Yamazaki, Hiromi; Fukumoto, Miki; Ito, Hiromi; Hayashi, Yasutaka; Kitamura, Toshio; Kawamoto, Hiroshi; Takaori-Kondo, Akifumi; Koseki, Haruhiko; Ogawa, Seishi; Inoue, Daichi.

Leukemia ; 37(9): 1802-1811, 2023 09.

Article in English | MEDLINE | ID: mdl-37464069

11.

Amplified EPOR/JAK2 Genes Define a Unique Subtype of Acute Erythroid Leukemia.

Takeda, June; Yoshida, Kenichi; Nakagawa, Masahiro M; Nannya, Yasuhito; Yoda, Akinori; Saiki, Ryunosuke; Ochi, Yotaro; Zhao, Lanying; Okuda, Rurika; Qi, Xingxing; Mori, Takuto; Kon, Ayana; Chiba, Kenichi; Tanaka, Hiroko; Shiraishi, Yuichi; Kuo, Ming-Chung; Kerr, Cassandra M; Nagata, Yasunobu; Morishita, Daisuke; Hiramoto, Nobuhiro; Hangaishi, Akira; Nakazawa, Hideyuki; Ishiyama, Ken; Miyano, Satoru; Chiba, Shigeru; Miyazaki, Yasushi; Kitano, Toshiyuki; Usuki, Kensuke; Sezaki, Nobuo; Tsurumi, Hisashi; Miyawaki, Shuichi; Maciejewski, Jaroslaw P; Ishikawa, Takayuki; Ohyashiki, Kazuma; Ganser, Arnold; Heuser, Michael; Thol, Felicitas; Shih, Lee-Yung; Takaori-Kondo, Akifumi; Makishima, Hideki; Ogawa, Seishi.

Blood Cancer Discov ; 3(5): 410-427, 2022 09 06.

Article in English | MEDLINE | ID: mdl-35839275

12.

A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells.

Yamamoto, Keita; Goyama, Susumu; Asada, Shuhei; Fujino, Takeshi; Yonezawa, Taishi; Sato, Naru; Takeda, Reina; Tsuchiya, Akiho; Fukuyama, Tomofusa; Tanaka, Yosuke; Yokoyama, Akihiko; Toya, Hikaru; Kon, Ayana; Nannya, Yasuhito; Onoguchi-Mizutani, Rena; Nakagawa, Shinichi; Hirose, Tetsuro; Ogawa, Seishi; Akimitsu, Nobuyoshi; Kitamura, Toshio.

Cell Rep ; 36(8): 109576, 2021 08 24.

Article in English | MEDLINE | ID: mdl-34433054

13.

Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.

Ochi, Yotaro; Kon, Ayana; Sakata, Toyonori; Nakagawa, Masahiro M; Nakazawa, Naotaka; Kakuta, Masanori; Kataoka, Keisuke; Koseki, Haruhiko; Nakayama, Manabu; Morishita, Daisuke; Tsuruyama, Tatsuaki; Saiki, Ryunosuke; Yoda, Akinori; Okuda, Rurika; Yoshizato, Tetsuichi; Yoshida, Kenichi; Shiozawa, Yusuke; Nannya, Yasuhito; Kotani, Shinichi; Kogure, Yasunori; Kakiuchi, Nobuyuki; Nishimura, Tomomi; Makishima, Hideki; Malcovati, Luca; Yokoyama, Akihiko; Takeuchi, Kengo; Sugihara, Eiji; Sato, Taka-Aki; Sanada, Masashi; Takaori-Kondo, Akifumi; Cazzola, Mario; Kengaku, Mineko; Miyano, Satoru; Shirahige, Katsuhiko; Suzuki, Hiroshi I; Ogawa, Seishi.

Cancer Discov ; 10(6): 836-853, 2020 06.

Article in English | MEDLINE | ID: mdl-32249213

14.

Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences.

Masaki, So; Ikeda, Shun; Hata, Asuka; Shiozawa, Yusuke; Kon, Ayana; Ogawa, Seishi; Suzuki, Kenji; Hakuno, Fumihiko; Takahashi, Shin-Ichiro; Kataoka, Naoyuki.

Front Genet ; 10: 338, 2019.

Article in English | MEDLINE | ID: mdl-31040863

15.

Molecular pathogenesis of disease progression in MLL-rearranged AML.

Kotani, Shinichi; Yoda, Akinori; Kon, Ayana; Kataoka, Keisuke; Ochi, Yotaro; Shiozawa, Yusuke; Hirsch, Cassandra; Takeda, June; Ueno, Hiroo; Yoshizato, Tetsuichi; Yoshida, Kenichi; Nakagawa, Masahiro M; Nannya, Yasuhito; Kakiuchi, Nobuyuki; Yamauchi, Takuji; Aoki, Kosuke; Shiraishi, Yuichi; Miyano, Satoru; Maeda, Takahiro; Maciejewski, Jaroslaw P; Takaori-Kondo, Akifumi; Ogawa, Seishi; Makishima, Hideki.

Leukemia ; 33(3): 612-624, 2019 03.

Article in English | MEDLINE | ID: mdl-30209403

16.

Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia.

Seki, Masafumi; Kimura, Shunsuke; Isobe, Tomoya; Yoshida, Kenichi; Ueno, Hiroo; Nakajima-Takagi, Yaeko; Wang, Changshan; Lin, Lin; Kon, Ayana; Suzuki, Hiromichi; Shiozawa, Yusuke; Kataoka, Keisuke; Fujii, Yoichi; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Shimamura, Teppei; Masuda, Kyoko; Kawamoto, Hiroshi; Ohki, Kentaro; Kato, Motohiro; Arakawa, Yuki; Koh, Katsuyoshi; Hanada, Ryoji; Moritake, Hiroshi; Akiyama, Masaharu; Kobayashi, Ryoji; Deguchi, Takao; Hashii, Yoshiko; Imamura, Toshihiko; Sato, Atsushi; Kiyokawa, Nobutaka; Oka, Akira; Hayashi, Yasuhide; Takagi, Masatoshi; Manabe, Atsushi; Ohara, Akira; Horibe, Keizo; Sanada, Masashi; Iwama, Atsushi; Mano, Hiroyuki; Miyano, Satoru; Ogawa, Seishi; Takita, Junko.

Nat Genet ; 49(8): 1274-1281, 2017 Aug.

Article in English | MEDLINE | ID: mdl-28671687

17.

Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome.

Sato, Yusuke; Maekawa, Shigekatsu; Ishii, Ryohei; Sanada, Masashi; Morikawa, Teppei; Shiraishi, Yuichi; Yoshida, Kenichi; Nagata, Yasunobu; Sato-Otsubo, Aiko; Yoshizato, Tetsuichi; Suzuki, Hiromichi; Shiozawa, Yusuke; Kataoka, Keisuke; Kon, Ayana; Aoki, Kosuke; Chiba, Kenichi; Tanaka, Hiroko; Kume, Haruki; Miyano, Satoru; Fukayama, Masashi; Nureki, Osamu; Homma, Yukio; Ogawa, Seishi.

Science ; 344(6186): 917-20, 2014 May 23.

Article in English | MEDLINE | ID: mdl-24855271

18.

Exome sequencing identifies secondary mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia.

Sakaguchi, Hirotoshi; Okuno, Yusuke; Muramatsu, Hideki; Yoshida, Kenichi; Shiraishi, Yuichi; Takahashi, Mariko; Kon, Ayana; Sanada, Masashi; Chiba, Kenichi; Tanaka, Hiroko; Makishima, Hideki; Wang, Xinan; Xu, Yinyan; Doisaki, Sayoko; Hama, Asahito; Nakanishi, Koji; Takahashi, Yoshiyuki; Yoshida, Nao; Maciejewski, Jaroslaw P; Miyano, Satoru; Ogawa, Seishi; Kojima, Seiji.

Nat Genet ; 45(8): 937-41, 2013 Aug.

Article in English | MEDLINE | ID: mdl-23832011

19.

Integrated molecular analysis of clear-cell renal cell carcinoma.

Sato, Yusuke; Yoshizato, Tetsuichi; Shiraishi, Yuichi; Maekawa, Shigekatsu; Okuno, Yusuke; Kamura, Takumi; Shimamura, Teppei; Sato-Otsubo, Aiko; Nagae, Genta; Suzuki, Hiromichi; Nagata, Yasunobu; Yoshida, Kenichi; Kon, Ayana; Suzuki, Yutaka; Chiba, Kenichi; Tanaka, Hiroko; Niida, Atsushi; Fujimoto, Akihiro; Tsunoda, Tatsuhiko; Morikawa, Teppei; Maeda, Daichi; Kume, Haruki; Sugano, Sumio; Fukayama, Masashi; Aburatani, Hiroyuki; Sanada, Masashi; Miyano, Satoru; Homma, Yukio; Ogawa, Seishi.

Nat Genet ; 45(8): 860-7, 2013 Aug.

Article in English | MEDLINE | ID: mdl-23797736

20.

The landscape of somatic mutations in Down syndrome-related myeloid disorders.

Yoshida, Kenichi; Toki, Tsutomu; Okuno, Yusuke; Kanezaki, Rika; Shiraishi, Yuichi; Sato-Otsubo, Aiko; Sanada, Masashi; Park, Myoung-ja; Terui, Kiminori; Suzuki, Hiromichi; Kon, Ayana; Nagata, Yasunobu; Sato, Yusuke; Wang, RuNan; Shiba, Norio; Chiba, Kenichi; Tanaka, Hiroko; Hama, Asahito; Muramatsu, Hideki; Hasegawa, Daisuke; Nakamura, Kazuhiro; Kanegane, Hirokazu; Tsukamoto, Keiko; Adachi, Souichi; Kawakami, Kiyoshi; Kato, Koji; Nishimura, Ryosei; Izraeli, Shai; Hayashi, Yasuhide; Miyano, Satoru; Kojima, Seiji; Ito, Etsuro; Ogawa, Seishi.

Nat Genet ; 45(11): 1293-9, 2013 Nov.

Article in English | MEDLINE | ID: mdl-24056718

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