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Bexton, Steve; Wiersma, Lidewij C; Getu, Sarah; van Run, Peter R; Verjans, Georges M G M; Schipper, Debby; Schapendonk, Claudia M E; Bodewes, Rogier; Oldroyd, Lucy; Haagmans, Bart L; Koopmans, Marion M P; Smits, Saskia L.

Emerg Infect Dis ; 21(7): 1205-8, 2015 Jul.

Article in English | MEDLINE | ID: mdl-26079061

ABSTRACT

A fox circovirus was identified in serum samples from foxes with unexplained neurologic signs by using viral metagenomics. Fox circovirus nucleic acid was localized in histological lesions of the cerebrum by in situ hybridization. Viruses from the family Circoviridae may have neurologic tropism more commonly than previously anticipated.

Subject(s)

Circoviridae Infections/veterinary , Circovirus/isolation & purification , Foxes/virology , Meningoencephalitis/veterinary , Animals , Brain/pathology , Brain/virology , Circoviridae Infections/diagnosis , Circoviridae Infections/virology , Circovirus/genetics , Female , Male , Meningoencephalitis/diagnosis , Meningoencephalitis/virology , Molecular Diagnostic Techniques , Real-Time Polymerase Chain Reaction , United Kingdom

ABSTRACT

Subject(s)

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