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1.

Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA.

Mowel, Walter K; McCright, Sam J; Kotzin, Jonathan J; Collet, Magalie A; Uyar, Asli; Chen, Xin; DeLaney, Alexandra; Spencer, Sean P; Virtue, Anthony T; Yang, EnJun; Villarino, Alejandro; Kurachi, Makoto; Dunagin, Margaret C; Pritchard, Gretchen Harms; Stein, Judith; Hughes, Cynthia; Fonseca-Pereira, Diogo; Veiga-Fernandes, Henrique; Raj, Arjun; Kambayashi, Taku; Brodsky, Igor E; O'Shea, John J; Wherry, E John; Goff, Loyal A; Rinn, John L; Williams, Adam; Flavell, Richard A; Henao-Mejia, Jorge.

Immunity ; 47(3): 435-449.e8, 2017 09 19.

Article in English | MEDLINE | ID: mdl-28930659

2.

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.

Tang, Alan T; Choi, Jaesung P; Kotzin, Jonathan J; Yang, Yiqing; Hong, Courtney C; Hobson, Nicholas; Girard, Romuald; Zeineddine, Hussein A; Lightle, Rhonda; Moore, Thomas; Cao, Ying; Shenkar, Robert; Chen, Mei; Mericko, Patricia; Yang, Jisheng; Li, Li; Tanes, Ceylan; Kobuley, Dmytro; Võsa, Urmo; Whitehead, Kevin J; Li, Dean Y; Franke, Lude; Hart, Blaine; Schwaninger, Markus; Henao-Mejia, Jorge; Morrison, Leslie; Kim, Helen; Awad, Issam A; Zheng, Xiangjian; Kahn, Mark L.

Nature ; 545(7654): 305-310, 2017 05 18.

Article in English | MEDLINE | ID: mdl-28489816

3.

Virus-specific CD4(+) memory-phenotype T cells are abundant in unexposed adults.

Su, Laura F; Kidd, Brian A; Han, Arnold; Kotzin, Jonathan J; Davis, Mark M.

Immunity ; 38(2): 373-83, 2013 Feb 21.

Article in English | MEDLINE | ID: mdl-23395677

4.

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.

Kotzin, Jonathan J; Spencer, Sean P; McCright, Sam J; Kumar, Dinesh B Uthaya; Collet, Magalie A; Mowel, Walter K; Elliott, Ellen N; Uyar, Asli; Makiya, Michelle A; Dunagin, Margaret C; Harman, Christian C D; Virtue, Anthony T; Zhu, Stella; Bailis, Will; Stein, Judith; Hughes, Cynthia; Raj, Arjun; Wherry, E John; Goff, Loyal A; Klion, Amy D; Rinn, John L; Williams, Adam; Flavell, Richard A; Henao-Mejia, Jorge.

Nature ; 537(7619): 239-243, 2016 09 08.

Article in English | MEDLINE | ID: mdl-27525555

5.

The long noncoding RNA Morrbid regulates CD8 T cells in response to viral infection.

Kotzin, Jonathan J; Iseka, Fany; Wright, Jasmine; Basavappa, Megha G; Clark, Megan L; Ali, Mohammed-Alkhatim; Abdel-Hakeem, Mohamed S; Robertson, Tanner F; Mowel, Walter K; Joannas, Leonel; Neal, Vanessa D; Spencer, Sean P; Syrett, Camille M; Anguera, Montserrat C; Williams, Adam; Wherry, E John; Henao-Mejia, Jorge.

Proc Natl Acad Sci U S A ; 116(24): 11916-11925, 2019 06 11.

Article in English | MEDLINE | ID: mdl-31138702

6.

Control of Immune Cell Homeostasis and Function by lncRNAs.

Mowel, Walter K; Kotzin, Jonathan J; McCright, Sam J; Neal, Vanessa D; Henao-Mejia, Jorge.

Trends Immunol ; 39(1): 55-69, 2018 01.

Article in English | MEDLINE | ID: mdl-28919048

7.

Immune checkpoint inhibitor therapy in patients with cancer and pre-existing systemic sclerosis.

Wallwork, Rachel S; Kotzin, Jonathan J; Cappelli, Laura C; Mecoli, Christopher; Bingham, Clifton O; Wigley, Fredrick M; Wilson, Parker C; DiRenzo, Dana D; Shah, Ami A.

Semin Arthritis Rheum ; 67: 152460, 2024 May 04.

Article in English | MEDLINE | ID: mdl-38733668

8.

Hyperglycemia cooperates with Tet2 heterozygosity to induce leukemia driven by proinflammatory cytokine-induced lncRNA Morrbid.

Cai, Zhigang; Lu, Xiaoyu; Zhang, Chi; Nelanuthala, Sai; Aguilera, Fabiola; Hadley, Abigail; Ramdas, Baskar; Fang, Fang; Nephew, Kenneth; Kotzin, Jonathan J; Williams, Adam; Henao-Mejia, Jorge; Haneline, Laura; Kapur, Reuben.

J Clin Invest ; 131(1)2021 01 04.

Article in English | MEDLINE | ID: mdl-33090974

9.

Role of lncRNA Morrbid in PTPN11(Shp2)E76K-driven juvenile myelomonocytic leukemia.

Cai, Zhigang; Zhang, Chi; Kotzin, Jonathan J; Williams, Adam; Henao-Mejia, Jorge; Kapur, Reuben.

Blood Adv ; 4(14): 3246-3251, 2020 07 28.

Article in English | MEDLINE | ID: mdl-32697817

10.

Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.

Cai, Zhigang; Aguilera, Fabiola; Ramdas, Baskar; Daulatabad, Swapna Vidhur; Srivastava, Rajneesh; Kotzin, Jonathan J; Carroll, Martin; Wertheim, Gerald; Williams, Adam; Janga, Sarath Chandra; Zhang, Chi; Henao-Mejia, Jorge; Kapur, Reuben.

Cell Rep ; 31(12): 107816, 2020 06 23.

Article in English | MEDLINE | ID: mdl-32579941

11.

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs.

Virtue, Anthony T; McCright, Sam J; Wright, Jasmine M; Jimenez, Monica T; Mowel, Walter K; Kotzin, Jonathan J; Joannas, Leonel; Basavappa, Megha G; Spencer, Sean P; Clark, Megan L; Eisennagel, Stephen H; Williams, Adam; Levy, Maayan; Manne, Sasikanth; Henrickson, Sarah E; Wherry, E John; Thaiss, Christoph A; Elinav, Eran; Henao-Mejia, Jorge.

Sci Transl Med ; 11(496)2019 06 12.

Article in English | MEDLINE | ID: mdl-31189717

12.

Radiotherapy and CD40 Activation Separately Augment Immunity to Checkpoint Blockade in Cancer.

Rech, Andrew J; Dada, Hannah; Kotzin, Jonathan J; Henao-Mejia, Jorge; Minn, Andy J; Twyman-Saint Victor, Christina; Vonderheide, Robert H.

Cancer Res ; 78(15): 4282-4291, 2018 08 01.

Article in English | MEDLINE | ID: mdl-29844122

13.

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.

Cai, Zhigang; Kotzin, Jonathan J; Ramdas, Baskar; Chen, Sisi; Nelanuthala, Sai; Palam, Lakshmi Reddy; Pandey, Ruchi; Mali, Raghuveer Singh; Liu, Yan; Kelley, Mark R; Sandusky, George; Mohseni, Morvarid; Williams, Adam; Henao-Mejia, Jorge; Kapur, Reuben.

Cell Stem Cell ; 23(6): 833-849.e5, 2018 12 06.

Article in English | MEDLINE | ID: mdl-30526882

14.

Viruses hijack a host lncRNA to replicate.

Kotzin, Jonathan J; Mowel, Walter K; Henao-Mejia, Jorge.

Science ; 358(6366): 993-994, 2017 11 24.

Article in English | MEDLINE | ID: mdl-29170219

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