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1.

A New Rapid-Acting Antidepressant.

Krystal, John H; Charney, Dennis S; Duman, Ronald S.

Cell ; 181(1): 7, 2020 04 02.

Article in English | MEDLINE | ID: mdl-32243798

2.

Psychiatric disorders: diagnosis to therapy.

Krystal, John H; State, Matthew W.

Cell ; 157(1): 201-14, 2014 Mar 27.

Article in English | MEDLINE | ID: mdl-24679536

3.

Ketamine and the neurobiology of depression: Toward next-generation rapid-acting antidepressant treatments.

Krystal, John H; Kaye, Alfred P; Jefferson, Sarah; Girgenti, Matthew J; Wilkinson, Samuel T; Sanacora, Gerard; Esterlis, Irina.

Proc Natl Acad Sci U S A ; 120(49): e2305772120, 2023 Dec 05.

Article in English | MEDLINE | ID: mdl-38011560

4.

Recent Advances in the Treatment of Treatment-Resistant Depression: A Narrative Review of Literature Published from 2018 to 2023.

Havlik, John L; Wahid, Syed; Teopiz, Kayla M; McIntyre, Roger S; Krystal, John H; Rhee, Taeho Greg.

Curr Psychiatry Rep ; 26(4): 176-213, 2024 04.

Article in English | MEDLINE | ID: mdl-38386251

5.

Effects of Altered Excitation-Inhibition Balance on Decision Making in a Cortical Circuit Model.

Lam, Norman H; Borduqui, Thiago; Hallak, Jaime; Roque, Antonio; Anticevic, Alan; Krystal, John H; Wang, Xiao-Jing; Murray, John D.

J Neurosci ; 42(6): 1035-1053, 2022 02 09.

Article in English | MEDLINE | ID: mdl-34887320

6.

Emraclidine, a novel positive allosteric modulator of cholinergic M4 receptors, for the treatment of schizophrenia: a two-part, randomised, double-blind, placebo-controlled, phase 1b trial.

Krystal, John H; Kane, John M; Correll, Christoph U; Walling, David P; Leoni, Matthew; Duvvuri, Sridhar; Patel, Shrinal; Chang, Ih; Iredale, Philip; Frohlich, Lillian; Versavel, Stacey; Perry, Pamela; Sanchez, Raymond; Renger, John.

Lancet ; 400(10369): 2210-2220, 2022 12 17.

Article in English | MEDLINE | ID: mdl-36528376

7.

A Non-D2-Receptor-Binding Drug for the Treatment of Schizophrenia.

Koblan, Kenneth S; Kent, Justine; Hopkins, Seth C; Krystal, John H; Cheng, Hailong; Goldman, Robert; Loebel, Antony.

N Engl J Med ; 382(16): 1497-1506, 2020 04 16.

Article in English | MEDLINE | ID: mdl-32294346

8.

A computational model for learning from repeated traumatic experiences under uncertainty.

Kaye, Alfred P; Rao, Manasa G; Kwan, Alex C; Ressler, Kerry J; Krystal, John H.

Cogn Affect Behav Neurosci ; 23(3): 894-904, 2023 Jun.

Article in English | MEDLINE | ID: mdl-37165181

9.

Mental health impact of the COVID-19 pandemic in U.S. military veterans: a population-based, prospective cohort study.

Hill, Melanie L; Nichter, Brandon; Na, Peter J; Norman, Sonya B; Morland, Leslie A; Krystal, John H; Pietrzak, Robert H.

Psychol Med ; 53(3): 945-956, 2023 02.

Article in English | MEDLINE | ID: mdl-34120667

10.

Positive personality traits moderate persistent high alcohol consumption, determined by polygenic risk in U.S. military veterans: results from a 10-year, population-based, observational cohort study.

Na, Peter; Zhou, Hang; Montalvo-Ortiz, Janitza L; Cabrera-Mendoza, Brenda; Petrakis, Ismene L; Krystal, John H; Polimanti, Renato; Gelernter, Joel; Pietrzak, Robert H.

Psychol Med ; 53(16): 7893-7901, 2023 Dec.

Article in English | MEDLINE | ID: mdl-37642191

11.

Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden.

Nichter, Brandon; Koller, Dora; De Angelis, Flavio; Wang, Jiawei; Girgenti, Matthew J; Na, Peter J; Hill, Melanie L; Norman, Sonya B; Krystal, John H; Gelernter, Joel; Polimanti, Renato; Pietrzak, Robert H.

Psychol Med ; 53(13): 6325-6333, 2023 10.

Article in English | MEDLINE | ID: mdl-36444557

12.

Psychosocial moderators of polygenic risk for suicidal ideation: Results from a 7-year population-based, prospective cohort study of U.S. veterans.

Na, Peter J; De Angelis, Flavio; Nichter, Brandon; Wendt, Frank R; Krystal, John H; Southwick, Steven M; Levey, Daniel F; Gelernter, Joel; Polimanti, Renato; Pietrzak, Robert H.

Mol Psychiatry ; 27(2): 1068-1074, 2022 02.

Article in English | MEDLINE | ID: mdl-34725455

13.

Imaging the effect of ketamine on synaptic density (SV2A) in the living brain.

Holmes, Sophie E; Finnema, Sjoerd J; Naganawa, Mika; DellaGioia, Nicole; Holden, Daniel; Fowles, Krista; Davis, Margaret; Ropchan, Jim; Emory, Paul; Ye, Yunpeng; Nabulsi, Nabeel; Matuskey, David; Angarita, Gustavo A; Pietrzak, Robert H; Duman, Ronald S; Sanacora, Gerard; Krystal, John H; Carson, Richard E; Esterlis, Irina.

Mol Psychiatry ; 27(4): 2273-2281, 2022 04.

Article in English | MEDLINE | ID: mdl-35165397

14.

Validation of ketamine as a pharmacological model of thalamic dysconnectivity across the illness course of schizophrenia.

Abram, Samantha V; Roach, Brian J; Fryer, Susanna L; Calhoun, Vince D; Preda, Adrian; van Erp, Theo G M; Bustillo, Juan R; Lim, Kelvin O; Loewy, Rachel L; Stuart, Barbara K; Krystal, John H; Ford, Judith M; Mathalon, Daniel H.

Mol Psychiatry ; 27(5): 2448-2456, 2022 05.

Article in English | MEDLINE | ID: mdl-35422467

15.

Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits.

Pathak, Gita A; Singh, Kritika; Wendt, Frank R; Fleming, Tyne W; Overstreet, Cassie; Koller, Dora; Tylee, Daniel S; De Angelis, Flavio; Cabrera Mendoza, Brenda; Levey, Daniel F; Koenen, Karestan C; Krystal, John H; Pietrzak, Robert H; O' Donell, Christopher; Gaziano, J Michael; Falcone, Guido; Stein, Murray B; Gelernter, Joel; Pasaniuc, Bogdan; Mancuso, Nicholas; Davis, Lea K; Polimanti, Renato.

Mol Psychiatry ; 27(3): 1394-1404, 2022 03.

Article in English | MEDLINE | ID: mdl-35241783

16.

Psychosocial Factors Associated With Accelerated GrimAge in Male U.S. Military Veterans.

Tamman, Amanda J F; Nagamatsu, Sheila; Krystal, John H; Gelernter, Joel; Montalvo-Ortiz, Janitza L; Pietrzak, Robert H.

Am J Geriatr Psychiatry ; 31(2): 97-109, 2023 02.

Article in English | MEDLINE | ID: mdl-36210262

17.

Dissecting the epigenomic differences between smoking and nicotine dependence in a veteran cohort.

Nagamatsu, Sheila Tiemi; Pietrzak, Robert H; Xu, Ke; Krystal, John H; Gelernter, Joel; Montalvo-Ortiz, Janitza Liz.

Addict Biol ; 28(1): e13259, 2023 01.

Article in English | MEDLINE | ID: mdl-36577721

18.

Reward and loss incentives improve spatial working memory by shaping trial-by-trial posterior frontoparietal signals.

Cho, Youngsun T; Moujaes, Flora; Schleifer, Charles H; Starc, Martina; Ji, Jie Lisa; Santamauro, Nicole; Adkinson, Brendan; Kolobaric, Antonija; Flynn, Morgan; Krystal, John H; Murray, John D; Repovs, Grega; Anticevic, Alan.

Neuroimage ; 254: 119139, 2022 07 01.

Article in English | MEDLINE | ID: mdl-35346841

19.

The Neurobiology and Pharmacotherapy of Posttraumatic Stress Disorder.

Abdallah, Chadi G; Averill, Lynnette A; Akiki, Teddy J; Raza, Mohsin; Averill, Christopher L; Gomaa, Hassaan; Adikey, Archana; Krystal, John H.

Annu Rev Pharmacol Toxicol ; 59: 171-189, 2019 01 06.

Article in English | MEDLINE | ID: mdl-30216745

20.

DNA methylation signature on phosphatidylethanol, not on self-reported alcohol consumption, predicts hazardous alcohol consumption in two distinct populations.

Liang, Xiaoyu; Justice, Amy C; So-Armah, Kaku; Krystal, John H; Sinha, Rajita; Xu, Ke.

Mol Psychiatry ; 26(6): 2238-2253, 2021 06.

Article in English | MEDLINE | ID: mdl-32034291

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