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1.

Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C.

Fakih, Marwan G; Salvatore, Lisa; Esaki, Taito; Modest, Dominik P; Lopez-Bravo, David P; Taieb, Julien; Karamouzis, Michalis V; Ruiz-Garcia, Erika; Kim, Tae-Won; Kuboki, Yasutoshi; Meriggi, Fausto; Cunningham, David; Yeh, Kun-Huei; Chan, Emily; Chao, Joseph; Saportas, Yaneth; Tran, Qui; Cremolini, Chiara; Pietrantonio, Filippo.

N Engl J Med ; 389(23): 2125-2139, 2023 Dec 07.

Article in English | MEDLINE | ID: mdl-37870968

2.

Whole-transcriptome sequencing in advanced gastric or gastroesophageal cancer: A deep dive into its clinical potential.

Hashimoto, Tadayoshi; Nakamura, Yoshiaki; Mishima, Saori; Nakayama, Izuma; Kotani, Daisuke; Kawazoe, Akihito; Kuboki, Yasutoshi; Bando, Hideaki; Kojima, Takashi; Iida, Naoko; Shibuki, Taro; Imai, Mitsuho; Fujisawa, Takao; Nagamine, Michiko; Sakamoto, Naoya; Kuwata, Takeshi; Yoshino, Takayuki; Shitara, Kohei.

Cancer Sci ; 115(5): 1622-1633, 2024 May.

Article in English | MEDLINE | ID: mdl-38429886

3.

A phase 1/1b, open-label, dose-escalation study of PD-1 inhibitor, cetrelimab alone and in combination with FGFR inhibitor, erdafitinib in Japanese patients with advanced solid tumors.

Yamamoto, Noboru; Kuboki, Yasutoshi; Harano, Kenichi; Koyama, Takafumi; Kondo, Shunsuke; Hagiwara, Akiko; Suzuki, Noriko; Fujikawa, Ei; Toyoizumi, Kiichiro; Mukai, Mayumi; Doi, Toshihiko.

Invest New Drugs ; 2024 Jun 04.

Article in English | MEDLINE | ID: mdl-38833067

4.

Phase I study of the irreversible fibroblast growth factor receptor 1-4 inhibitor futibatinib in Japanese patients with advanced solid tumors.

Doi, Toshihiko; Shitara, Kohei; Kojima, Takashi; Kuboki, Yasutoshi; Matsubara, Nobuaki; Bando, Hideaki; Yoh, Kiyotaka; Naito, Yoichi; Hirai, Hiroshi; Kurokawa, Yukinori; Kato, Terufumi; Morizane, Chigusa.

Cancer Sci ; 114(2): 574-585, 2023 Feb.

Article in English | MEDLINE | ID: mdl-35838190

5.

First-in-human study of E7130 (a tumor microenvironment-ameliorating microtubule inhibitor) in patients with advanced solid tumors: Primary results of the dose-escalation part.

Doi, Toshihiko; Matsubara, Nobuaki; Naito, Yoichi; Kuboki, Yasutoshi; Harano, Kenichi; Ono, Makiko; Urasaki, Tetsuya; Ohmoto, Akihiro; Kawanai, Tsubasa; Hisai, Takashi; Ikezawa, Hiroki; Shiba, Sari; Ito, Ken; Semba, Taro; Asano, Osamu; Takahashi, Shunji.

Cancer ; 129(15): 2348-2359, 2023 08 01.

Article in English | MEDLINE | ID: mdl-37080942

6.

Trifluridine/tipiracil+bevacizumab (BEV) vs. fluoropyrimidine-irinotecan+BEV as second-line therapy for metastatic colorectal cancer: a randomised noninferiority trial.

Kuboki, Yasutoshi; Terazawa, Tetsuji; Masuishi, Toshiki; Nakamura, Masato; Watanabe, Jun; Ojima, Hitoshi; Makiyama, Akitaka; Kotaka, Masahito; Hara, Hiroki; Kagawa, Yoshinori; Sugimoto, Naotoshi; Kawakami, Hisato; Takashima, Atsuo; Kajiwara, Takeshi; Oki, Eiji; Sunakawa, Yu; Ishihara, Soichiro; Taniguchi, Hiroya; Nakajima, Takako Eguchi; Morita, Satoshi; Shirao, Kuniaki; Takenaka, Naruhito; Ozawa, Daisuke; Yoshino, Takayuki.

Br J Cancer ; 128(10): 1897-1905, 2023 05.

Article in English | MEDLINE | ID: mdl-36871043

7.

KRAS^G12C Inhibition with Sotorasib in Advanced Solid Tumors.

Hong, David S; Fakih, Marwan G; Strickler, John H; Desai, Jayesh; Durm, Gregory A; Shapiro, Geoffrey I; Falchook, Gerald S; Price, Timothy J; Sacher, Adrian; Denlinger, Crystal S; Bang, Yung-Jue; Dy, Grace K; Krauss, John C; Kuboki, Yasutoshi; Kuo, James C; Coveler, Andrew L; Park, Keunchil; Kim, Tae Won; Barlesi, Fabrice; Munster, Pamela N; Ramalingam, Suresh S; Burns, Timothy F; Meric-Bernstam, Funda; Henary, Haby; Ngang, Jude; Ngarmchamnanrith, Gataree; Kim, June; Houk, Brett E; Canon, Jude; Lipford, J Russell; Friberg, Gregory; Lito, Piro; Govindan, Ramaswamy; Li, Bob T.

N Engl J Med ; 383(13): 1207-1217, 2020 09 24.

Article in English | MEDLINE | ID: mdl-32955176

8.

Efficacy and safety of trifluridine/tipiracil plus ramucirumab in comparison with trifluridine/tipiracil monotherapy for patients with advanced gastric cancer-single institutional experience.

Okunaka, Mashiro; Kawazoe, Akihito; Nakamura, Hitomi; Kotani, Daisuke; Mishima, Saori; Kuboki, Yasutoshi; Nakamura, Yoshiaki; Shitara, Kohei.

Gastric Cancer ; 26(6): 1030-1039, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37665515

9.

[Japan or Global Development Trends in Cell Therapy].

Kuboki, Yasutoshi.

Gan To Kagaku Ryoho ; 50(10): 1027-1031, 2023 Oct.

Article in Japanese | MEDLINE | ID: mdl-38035828

10.

Sotorasib for previously treated colorectal cancers with KRAS^G12C mutation (CodeBreaK100): a prespecified analysis of a single-arm, phase 2 trial.

Fakih, Marwan G; Kopetz, Scott; Kuboki, Yasutoshi; Kim, Tae Won; Munster, Pamela N; Krauss, John C; Falchook, Gerald S; Han, Sae-Won; Heinemann, Volker; Muro, Kei; Strickler, John H; Hong, David S; Denlinger, Crystal S; Girotto, Gustavo; Lee, Myung-Ah; Henary, Haby; Tran, Qui; Park, Joseph K; Ngarmchamnanrith, Gataree; Prenen, Hans; Price, Timothy J.

Lancet Oncol ; 23(1): 115-124, 2022 01.

Article in English | MEDLINE | ID: mdl-34919824

11.

A phase 1 trial of xentuzumab, an IGF-neutralizing antibody, in Japanese patients with advanced solid tumors.

Doi, Toshihiko; Kuboki, Yasutoshi; Naito, Yoichi; Ishida, Masahiro; Tanaka, Tetsuya; Takeuchi, Yoshito.

Cancer Sci ; 113(3): 1010-1017, 2022 Mar.

Article in English | MEDLINE | ID: mdl-34870878

12.

Tisotumab vedotin in Japanese patients with recurrent/metastatic cervical cancer: Results from the innovaTV 206 study.

Yonemori, Kan; Kuboki, Yasutoshi; Hasegawa, Kosei; Iwata, Takashi; Kato, Hidenori; Takehara, Kazuhiro; Hirashima, Yasuyuki; Kato, Hisamori; Passey, Chaitali; Buchbjerg, Jeppe Klint; Harris, Jeffrey R; Andreassen, Camilla Mondrup; Nicacio, Leonardo; Soumaoro, Ibrahima; Fujiwara, Keiichi.

Cancer Sci ; 113(8): 2788-2797, 2022 Aug.

Article in English | MEDLINE | ID: mdl-35633184

13.

Phase I trial of the DLL3/CD3 bispecific T-cell engager BI 764532 in DLL3-positive small-cell lung cancer and neuroendocrine carcinomas.

Wermke, Martin; Felip, Enriqueta; Gambardella, Valentina; Kuboki, Yasutoshi; Morgensztern, Daniel; Hamed, Zohra Oum'; Liu, Meiruo; Studeny, Matus; Owonikoko, Taofeek K.

Future Oncol ; 18(24): 2639-2649, 2022 Aug.

Article in English | MEDLINE | ID: mdl-35815644

14.

Characteristics and clinical outcomes of patients with advanced gastric or gastroesophageal cancer treated in and out of randomized clinical trials of first-line immune checkpoint inhibitors.

Aoki, Yu; Kawazoe, Akihito; Kubota, Yohei; Chida, Keigo; Mishima, Saori; Kotani, Daisuke; Nakamura, Yoshiaki; Kuboki, Yasutoshi; Bando, Hideaki; Kojima, Takashi; Doi, Toshihiko; Yoshino, Takayuki; Kuwata, Takeshi; Shitara, Kohei.

Int J Clin Oncol ; 27(9): 1413-1420, 2022 Sep.

Article in English | MEDLINE | ID: mdl-35713753

15.

Guidelines for clinical evaluation of anti-cancer drugs.

Minami, Hironobu; Kiyota, Naomi; Kimbara, Shiro; Ando, Yuichi; Shimokata, Tomoya; Ohtsu, Atsushi; Fuse, Nozomu; Kuboki, Yasutoshi; Shimizu, Toshio; Yamamoto, Noboru; Nishio, Kazuto; Kawakami, Yutaka; Nihira, Shin-Ichi; Sase, Kazuhiro; Nonaka, Takahiro; Takahashi, Hideaki; Komori, Yukiko; Kiyohara, Koshin.

Cancer Sci ; 112(7): 2563-2577, 2021 Jul.

Article in English | MEDLINE | ID: mdl-33990993

16.

Safety, pharmacokinetics, and preliminary efficacy of the PARP inhibitor talazoparib in Japanese patients with advanced solid tumors: phase 1 study.

Naito, Yoichi; Kuboki, Yasutoshi; Ikeda, Masafumi; Harano, Kenichi; Matsubara, Nobuaki; Toyoizumi, Shigeyuki; Mori, Yuko; Hori, Natsuki; Nagasawa, Takashi; Kogawa, Takahiro.

Invest New Drugs ; 39(6): 1568-1576, 2021 12.

Article in English | MEDLINE | ID: mdl-34160752

17.

Study protocol for NCCH1908 (UPFRONT-trial): a prospective clinical trial to evaluate the feasibility and utility of comprehensive genomic profiling prior to the initial systemic treatment in advanced solid tumour patients.

Mizuno, Takaaki; Yoshida, Tatsuya; Sunami, Kuniko; Koyama, Takafumi; Okita, Natsuko; Kubo, Takashi; Sudo, Kazuki; Shimoi, Tatsunori; Ueno, Hideki; Saito, Eiko; Katanoda, Kota; Shibata, Taro; Yonemori, Kan; Okusaka, Takuji; Boku, Narikazu; Ohe, Yuichiro; Hiroshima, Yukihiko; Ueno, Makoto; Kuboki, Yasutoshi; Doi, Toshihiko; Nakamura, Kenichi; Kohno, Takashi; Yatabe, Yasushi; Yamamoto, Noboru.

Jpn J Clin Oncol ; 51(12): 1757-1760, 2021 Dec 01.

Article in English | MEDLINE | ID: mdl-34622931

18.

Safety and efficacy of panitumumab in combination with trifluridine/tipiracil for pre-treated patients with unresectable, metastatic colorectal cancer with wild-type RAS: The phase 1/2 APOLLON study.

Kato, Takeshi; Kagawa, Yoshinori; Kuboki, Yasutoshi; Gamoh, Makio; Komatsu, Yoshito; Yasui, Hirofumi; Satake, Hironaga; Oki, Eiji; Tanioka, Hiroaki; Kotaka, Masahito; Makiyama, Akitaka; Denda, Tadamichi; Goto, Masahiro; Yoshino, Takayuki; Yamazaki, Kentaro; Soeda, Junpei; Shibuya, Kazunori; Iwata, Masaru; Oba, Koji; Yamaguchi, Kensei.

Int J Clin Oncol ; 26(7): 1238-1247, 2021 Jul.

Article in English | MEDLINE | ID: mdl-33928486

19.

Lenvatinib plus pembrolizumab in patients with advanced gastric cancer in the first-line or second-line setting (EPOC1706): an open-label, single-arm, phase 2 trial.

Kawazoe, Akihito; Fukuoka, Shota; Nakamura, Yoshiaki; Kuboki, Yasutoshi; Wakabayashi, Masashi; Nomura, Shogo; Mikamoto, Yuichi; Shima, Hikari; Fujishiro, Noriko; Higuchi, Tsukiko; Sato, Akihiro; Kuwata, Takeshi; Shitara, Kohei.

Lancet Oncol ; 21(8): 1057-1065, 2020 08.

Article in English | MEDLINE | ID: mdl-32589866

20.

Enhanced tumor response to radiotherapy after PD-1 blockade in metastatic gastric cancer.

Sasaki, Akinori; Nakamura, Yoshiaki; Togashi, Yosuke; Kuno, Hirofumi; Hojo, Hidehiro; Kageyama, Shunichiro; Nakamura, Naoki; Takashima, Kenji; Kadota, Tomohiro; Yoda, Yusuke; Mishima, Saori; Sawada, Kentaro; Kotani, Daisuke; Kawazoe, Akihito; Kuboki, Yasutoshi; Taniguchi, Hiroya; Kojima, Takashi; Doi, Toshihiko; Yoshino, Takayuki; Yano, Tomonori; Kobayashi, Tatsushi; Akimoto, Tetsuo; Nishikawa, Hiroyoshi; Shitara, Kohei.

Gastric Cancer ; 23(5): 893-903, 2020 09.

Article in English | MEDLINE | ID: mdl-32180056

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