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1.
Rev Med Liege ; 76(4): 280-286, 2021 Apr.
Article in French | MEDLINE | ID: mdl-33830693

ABSTRACT

This prospective study aims to evaluate both benefits and limitations of dysphagia screening tools (DePippo, EAT10, V-VST, the IOPI tongue-strength assessment) used in a geriatric unit. Among the 102 patients under study, 47 showed a dysphagia diagnosed by full logopedic examination. The sensitivity and the specificity of the screening tools were, respectively, 31,9 % and 83,6 % for EAT10, 86,9 % and 52,7 % for the V-VST and 76,6 % and 65,0 % for the DePippo test. Regarding the posterior tongue strength assessment, the threshold value of 31kPA showed an 77,3 % sensitivity and a 52,7 % specificity. Given the results obtained from the above-mentioned screening tools and their practical application limitations, the DePippo test appears to be the most convenient for a day-to-day geriatric utilization. Finally, this study outlines the necessity of confirming, in a larger sample, the reproducibility of the DePippo test as well as the interest of measuring the tongue strength among frail older people.


L'objectif de cette étude prospective était d'évaluer l'intérêt et les limites d'outils de dépistage de la dysphagie (DePippo, EAT10, V-VST, mesure de la force de langue par IOPI) lors de leur utilisation au sein d'un service de gériatrie. Parmi les 102 patients inclus, 47 présentaient une dysphagie relevée par une évaluation logopédique complète. La sensibilité et la spécificité des tests de dépistage ont été respectivement de 31,9 % et 83,6 % pour l'EAT10, de 86,9 % et 52,7 % pour le V-VST, et de 76,6 % et 65,0 % pour le test de DePippo. Concernant la force postérieure de la langue, la valeur seuil minimale de 31 kPa présentait une sensibilité de 77,3 % et une spécificité de 52,7 %. Bien que moins sensible que le V-VST, le test de DePippo (test à l'eau) est plus largement applicable aux patients fragiles hospitalisés en gériatrie. De plus, cette étude met en lumière la nécessité de préciser, au sein d'un échantillon plus large, la reproductibilité du test de DePippo et l'intérêt de la mesure de la force de langue. En conclusion, et sous réserve de son taux de reproductibilité à préciser, le test de DePippo apparaît, actuellement, être l'outil de dépistage le plus adapté à une utilisation en gériatrie.


Subject(s)
Deglutition Disorders , Aged , Aged, 80 and over , Deglutition Disorders/diagnosis , Geriatric Assessment , Humans , Prospective Studies , Reproducibility of Results
2.
Rev Neurol (Paris) ; 176(7-8): 608-613, 2020 Sep.
Article in English | MEDLINE | ID: mdl-32164972

ABSTRACT

INTRODUCTION: Multiple system atrophy (MSA) is a neurodegenerative disorder in which vocal fold mobility can be affected, sometimes leading to life-threatening situations. Our aim was to know if laryngeal examination could help differentiate MSA from Parkinson's disease (PD). MATERIALS AND METHODS: Between 2004 to 2014, all consecutive patients diagnosed with probable MSA were included in this retrospective, monocentric study. Flexible laryngoscopy was obtained in 51 MSA patients and compared with 27 patients with Parkinson's disease (PD). Laryngeal muscles EMG was available in 6 MSA patients. RESULTS: Vocal fold motion impairments (VFMI) was found in 35 (68.6%) MSA patients: 15 (29.4%) had uni- or bilateral vocal fold abnormal movement (VFAM), 13 (25.5%) had uni- or bilateral vocal fold abductor paresis (VFABP), 4 (7.8%) had uni- or bilateral vocal fold adductor paresis (VFADP), 10 (19.6%) had bilateral vocal fold paralysis (BVFP). VFMI was found in 13 PD patients (48.1%) all of whom had VFADP. Presence of BVFP was found associated with stridor (P<0.001) and dysphagia (P=0.002). In all muscles examined in 6 MSA patients, the EMG showed neuropathic patterns. CONCLUSIONS: Our data support that VFMI may be encountered in two-thirds of MSA with a variable degree of gravity. Laryngological examination should be considered as a supplementary tool for the diagnosis and prognosis of MSA. VFMI in particular VFAM, VFABD and BVFP should be discussed as an additional possible red flag even at an early stage of MSA and could help discriminate MSA from PD.


Subject(s)
Multiple System Atrophy , Parkinson Disease , Humans , Prevalence , Retrospective Studies , Vocal Cords
3.
Rev Med Liege ; 74(12): 633-636, 2019 Dec.
Article in French | MEDLINE | ID: mdl-31833272

ABSTRACT

We report the unexpected discovery of a large laryngeal neurofibroma during a direct laryngoscopy for intubation in a 18-year old female with a medical history of neurofibromatosis type 1. The most striking feature of this case report is the discrepancy between the absence of clinical manifestations and the size and location of the neurofibroma. This case highlights the importance of a careful preoperative assessment, especially in the context of multisystemic disease. Knowledge of the disease, recognition of related complications and adequate preoperative evaluation are crucial to establish the safest anesthesia strategy.


Nous rapportons la découverte fortuite d'un volumineux neurofibrome laryngé lors de la laryngoscopie précédant une intubation endotrachéale chez une patiente de 18 ans atteinte d'une neurofibromatose de type 1, par ailleurs asymptomatique. Ce cas est remarquable par l'absence de toute manifestation clinique rapportée par la patiente malgré le volumineux neurofibrome présent dans le larynx. Il souligne l'importance d'une mise au point préopératoire approfondie, particulièrement dans le cas de maladies multisystémiques. Une bonne connaissance de cette maladie et de ses complications est indispensable pour réaliser un bilan préopératoire adéquat et déterminer la stratégie d'anesthésie la plus adaptée à ces patients.


Subject(s)
Laryngeal Neoplasms , Neurofibroma , Adolescent , Anesthesia , Female , Humans , Incidental Findings , Intubation, Intratracheal , Laryngeal Neoplasms/diagnosis , Laryngoscopy , Neurofibroma/diagnosis
4.
Eur Arch Otorhinolaryngol ; 272(12): 3843-9, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26156226

ABSTRACT

Partial frontolateral laryngectomy (PL) is performed to remove larynx tumor while preserving its main functions. So far, the speech changes induced by difficulties of voicing and the alterations to the vocal tract due to PL have been seldom addressed. The goal of our study was to make an acoustic analysis of regressive voicing assimilation (RVA) among patients after PL and to study the relationship with rates of speech. A retrospective study was conducted from January to April 2013. 11 subjects treated by partial frontolateral laryngectomy, and ten healthy subjects were included. Functional recordings of voice were analyzed and compared. For assimilation sequences we found a significant modification of voicing ratio in healthy subjects (p < 0.05) and PL patient at accelerated speaking rate only (p < 0.05). The vowel duration is significantly modified only for healthy subjects. For all subjects (PL patients and healthy) the duration of C1 consonant was not significantly modified. Our results highlight the presence of RVA in healthy subjects, but also in PL patients in the rapid speaking mode.


Subject(s)
Laryngeal Neoplasms/surgery , Laryngectomy/methods , Phonetics , Speech, Alaryngeal , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Pilot Projects , Retrospective Studies
5.
Rev Laryngol Otol Rhinol (Bord) ; 136(5): 181-4, 2015.
Article in French | MEDLINE | ID: mdl-29400042

ABSTRACT

Objective: Dysfunctional swallowing may cause transverse occlusal disorders. The speech re-education of dysfunctional swallowing aims to correct or prevent the recurrence of occlu­sal disorders. The main objective was to test the dynamic palato­graphy as a diagnosis and quantification tool of the dysfunctional swallowing. Material and methods: The study was prospective and descriptive. Twelve average 23.5 years old women with a clinical dysfunctional swallowing have been included between January and May 2014. None was aware of presenting an atypical swallowing or dento-facial dysmorphism of class II. The dynamic palatography device measured the pressure force of the language on the palate during the lingual rest, swallowing saliva and water. Parameters measured were the duration and magnitude of support of the tongue on the palate. Results: Dynamic palatography showed a trend to predominant anterior contact during rest position (25%), and lower position of the language with little contact during swallo­wing of saliva and water. Discussion: Palatography results are consistent with the clinical diagnostic criteria of atypical swallo­wing. Our palatography tool has the advantage of being unobtrusive in the mouth compared to other pre existing systems. This device should be tested on larger patient popu­la­tions and could enable monitore atypical swallowing rehabili­ta­tion efficiency. The palatography could complete the swallo­wing assessment and be a monitoring and rehabilitation tool in real time.


Subject(s)
Deglutition Disorders/diagnosis , Speech Production Measurement/instrumentation , Adolescent , Adult , Feasibility Studies , Female , Humans , Prospective Studies , Young Adult
6.
Morphologie ; 98(320): 32-9, 2014 Mar.
Article in French | MEDLINE | ID: mdl-24637042

ABSTRACT

INTRODUCTION: The objective of the study was to determine the preferential territories of drainage of skin areas of the face and neck. This knowledge can guide the strategies of diagnostic (search for primary tumor skin to cervical lymphadenopathy) and treatment (determination of the extent of neck dissection to achieve in case of skin tumor). MATERIALS AND METHODS: This is a retrospective study of the surgical procedures of sentinel node research between January 2003 and April 2011. The lymphoscintigraphic and intraoperative localization of the initial tumor site and sentinel lymph node were collected. RESULTS AND DISCUSSION: One hundred and thirty-seven patients were included in the study. The parotid gland is a privileged territory of drainage of the head and neck skin. At cervical level, the submental region drains the lower and median part of the face (lips and chin). The posterior segments (IIb and V sector) were represented for the posterior locations of the head (ear, vertex), and cervical region.


Subject(s)
Head and Neck Neoplasms/pathology , Skin Neoplasms/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Lymphatic Metastasis/diagnostic imaging , Lymphatic Metastasis/pathology , Lymphoscintigraphy , Male , Middle Aged , Retrospective Studies , Sentinel Lymph Node Biopsy , Young Adult
7.
Rev Laryngol Otol Rhinol (Bord) ; 135(2): 83-6, 2014.
Article in French | MEDLINE | ID: mdl-26521346

ABSTRACT

INTRODUCTION: The exercises performed during the reeducation of swallowing seek to improve forces of propulsion of the bolus and airway protection during the course of swallowing. The objective of this study was to objectify the effect of pronunciation praxis of posterior phonemes /aka/ and /akra/, and swallowing maneuvers (super-supraglottic swallow with or without superimposed effort swallowing effort) on the time of the oral swallowing. MATERIALS AND METHODS: Four healthy volunteers participated in the experiment. They are called "experts" because they have a good knowledge of physiology and rehabilitation of swallowing. The dynamic palatography setup measured continuously the different pressures from the tongue on the hard palate through three force sensors arranged in a sagittal plane during the implementation of articulatory and swallowing tasks. RESULTS: Articulatory praxis created significant pressure on the posterior sensor for 2 of the 4 subjects. All the swallowing maneuvers increased the contact pressure and the contact duration compared to the control swallowing for the anterior and posterior pressure sensor. A large inter-individual variability was found. CONCLUSION: The complexity of instruction, the inter-individual variability in their performance, and the non-invasive nature of the instrument make the dynamic palatography a potentially useful tool in routine practice of swallowing reeducation.


Subject(s)
Deglutition Disorders/rehabilitation , Deglutition , Exercise Therapy , Palate, Hard , Pressure , Tongue , Adult , Deglutition Disorders/physiopathology , Exercise Therapy/methods , Female , Humans , Male , Palate, Hard/physiopathology , Time Factors , Treatment Outcome
9.
Rev Stomatol Chir Maxillofac ; 111(3): 152-4, 2010 Jun.
Article in French | MEDLINE | ID: mdl-20299067

ABSTRACT

Some losses of matter in the posterior area of the oral cavity require reconstruction with vascularized tissue to prevent retraction and a limited mouth opening. Bichat's fat pad or Bichat's fat ball is rarely used for oral mucosal reconstruction despite its proximity, easy availability, plasticity and simple use as a flap. Bichat's fat pad is resistant to lipolysis even in case of major weight-loss. It usually herniates in the exeresis site of a jugal tumor or intermaxillary commissure. When this is not the case, it can be obtained by a horizontal vestibular incision. The fat pad is unfolded and sutured without tension to the margin of the defect. The flap may be protected by a Bourdonnet dressing. Epithelialization begins 8 to 10 days after surgery. It is completed in the second or third week. The fat volume is variable, thus filling can only be applied to areas with loss of matter under 6cm. The technique is simple and quick. Postoperative evolution is usually uneventful; healing is quick as well as recovery of normal feeding function.


Subject(s)
Adipose Tissue/transplantation , Mouth Diseases/surgery , Plastic Surgery Procedures/methods , Adipose Tissue/pathology , Alginates/therapeutic use , Bandages , Biocompatible Materials/therapeutic use , Cheek/surgery , Epithelium/physiopathology , Fasciotomy , Glucuronic Acid/therapeutic use , Hexuronic Acids/therapeutic use , Humans , Lip Diseases/surgery , Mouth Mucosa/surgery , Surgical Flaps , Suture Techniques , Tissue and Organ Harvesting/methods , Wound Healing/physiology
10.
Morphologie ; 94(305): 9-12, 2010 May.
Article in French | MEDLINE | ID: mdl-20149707

ABSTRACT

AIM OF THE STUDY: Lymph node involvement is one of the most significant prognostic factors of patients with rectal cancer. Despite major advances in our understanding of the propagation of the rectal cancer, the lymphatic drainage of the rectum remains unclear. This study was designed to assess the number of lymph nodes located around the superior rectal artery and to assess the frequency of Mondor's lymph nodes. PATIENTS AND METHODS: Twenty-five anatomic subjects were studied. All resections were performed using total mesorectal excision. Lymph nodes were sought in the tissue surrounding the superior rectal artery up to 2 cm under the ending of the superior rectal artery by manual dissection and were submitted for histological examination. The correlation between the number of lymph nodes, and the volume and weight of the tissue surrounding the superior rectal artery was evaluated by non-parametric Spearman test. RESULTS: The mean number of lymph nodes per specimen was 2.7 +/- 1.4. The size of the lymph nodes varied between 1 and 7 mm. The lymph nodes were mostly smaller than 3 mm (56%). The number of lymph nodes in the superior rectal mesentery was independent of its volume and its weight. Seven subjects had a Mondor's lymph node. The mean size of Mondor's lymph node was 3.4 +/- 2.1 cm. CONCLUSIONS: The number of NL located around the superior rectal artery is small, varying between 1 and 5. The Mondor's lymph node is an inconstant rectal NL. Its only characteristic is its location in the bifurcation or trifurcation of the superior rectal artery.


Subject(s)
Lymph Nodes/pathology , Rectal Neoplasms/pathology , Dissection/methods , Female , Humans , Lymph Nodes/anatomy & histology , Male , Mesenteric Artery, Inferior/anatomy & histology , Mesenteric Artery, Inferior/pathology , Mesenteric Artery, Superior/anatomy & histology , Mesenteric Artery, Superior/pathology , Neoplasm Staging , Rectal Neoplasms/blood supply
11.
Rev Laryngol Otol Rhinol (Bord) ; 131(1): 15-8, 2010.
Article in French | MEDLINE | ID: mdl-21086655

ABSTRACT

OBJECTIVES: Whispered voice is investigated from the energetic point of view. Our hypothese is that whispered voice, and mainly the forced whispers are very similar to vocal effort, for non acoustic vocal parameters, and body movements. DESIGN: Two experiments are combined. The first experiment focused on the laryngeal aspects, mainly the subglottal pressure, and also the electroglottography. The second experiment analyzed the body movements associated with loud whispered voice. RESULTS: No electroglottograhic wave was observed during the two experiments. The vocal intensity was always lower during whispered voice than during comfortable voice (p < 0.001). In experiment 1, subglottal pressure was significantly higher during forced whisper than during the other conditions (p < 0.001). In experiment 2, the amplitude of the trunk movements in the sagittal plane were greater during loud whisper than during comfortable voice (p < 0.001). CONCLUSION: Whispered voice can be close to vocal loading, especially the loud whispered voice.


Subject(s)
Phonation , Voice , Adult , Female , Humans , Male , Middle Aged , Phonation/physiology , Posture , Vocal Cords/physiology , Voice/physiology , Voice Quality
12.
Eur Ann Otorhinolaryngol Head Neck Dis ; 137(3): 173-175, 2020 May.
Article in English | MEDLINE | ID: mdl-32332004

ABSTRACT

Procedures putting healthcare workers in close contact with the airway are particularly at risk of contamination by the SARS-Cov-2 virus, especially when exposed to sputum, coughing, or a tracheostomy. In the current pandemic phase, all patients should be considered as potentially infected. Thus, the level of precaution recommended for the caregivers depends more on the type of procedure than on the patient's proved or suspected COVID-19 status. Procedures that are particularly at high risk of contamination are clinical and flexible endoscopic pharyngo-laryngological evaluation, and probably also video fluoroscopic swallowing exams. Voice rehabilitation should not be considered urgent at this time. Therefore, recommendations presented here mainly concern the management of swallowing disorders, which can sometimes be dangerous for the patient, and recent dysphonia. In cases where they are considered possible and useful, teleconsultations should be preferred to face-to-face assessments or rehabilitation sessions. The latter must be maintained only in few selected situations, after team discussions or in accordance with the guidelines provided by health authorities.


Subject(s)
Coronavirus Infections/prevention & control , Deglutition Disorders/therapy , Dysphonia/therapy , Otolaryngology/methods , Otolaryngology/standards , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Betacoronavirus/isolation & purification , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Coronavirus Infections/virology , Deglutition Disorders/diagnosis , Deglutition Disorders/virology , Dysphonia/diagnosis , Dysphonia/virology , Humans , Infection Control/methods , Infection Control/standards , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , Pneumonia, Viral/virology , SARS-CoV-2
13.
Rev Laryngol Otol Rhinol (Bord) ; 130(1): 11-6, 2009.
Article in French | MEDLINE | ID: mdl-19530518

ABSTRACT

INTRODUCTION: The objective of the study was to assess how posture and vocal acoustics are modified when one needs to communicate despite environmental obstacles (i.e. vocal effort performance). METHOD: 20 healthy young women participated to this study. They had to communicate numbers to a listener. Environmental obstacles were the distance between the subject and the auditor, and the noise. Segmental posture modifications were recorded and analyzed using the numerical infra-red system for movement analysis SMART. Vocal acoustics and electroglottography were also recorded and analyzed using the EVA system. RESULTS: The study showed the presence of objective postural modifications during vocal effort. Their amplitude increased when the environmental obstacles to communications increased, and they anticipated the vocal production. DISCUSSION: The vocal effort concept and its relation with the posture, the voice and the subject's feeling are reviewed on the basis of these results. Laryngeal effort is not isolated, but belongs to a global behavioral strategy which aims to improving the efficiency of the communication.


Subject(s)
Posture , Voice/physiology , Adult , Female , Humans , Young Adult
14.
Rev Laryngol Otol Rhinol (Bord) ; 130(4-5): 313-5, 2009.
Article in French | MEDLINE | ID: mdl-20597420

ABSTRACT

We report a case of a patient who self-injured her ear and peri-auricular skin. Self-mutilation is an unusual behaviour in ENT practice. We give some elements for the diagnosis and treatment, and we emphasize the importance of the psychiatric treatment. The suicidal risk makes the vital prognosis uncertain.


Subject(s)
Borderline Personality Disorder/psychology , Ear, External/injuries , Self-Injurious Behavior/diagnosis , Borderline Personality Disorder/diagnosis , Ear, External/surgery , Female , Humans , Middle Aged , Self-Injurious Behavior/psychology
15.
Eur Ann Otorhinolaryngol Head Neck Dis ; 136(3): 151-154, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30880033

ABSTRACT

OBJECTIVES: To develop an experimental protocol to study the vocal effort generated by introducing barriers to communication, and its relationship with certain personality traits. MATERIAL AND METHODS: The experimental protocol consisted of an interactive game in which the subject gave an investigator instructions to adopt various body positions (semi-directed communication situation). The Control situation included no constraints on communication. Then a Distance Constraint (increased distance between subject and investigator) and a Time Constraint (generation of performance stress by putting the subject in competition with others) were introduced. The vocal parameters studied comprised vocal intensity and fundamental frequency in the middle of the vowel of 3 target phonemes. Subjects also took the NEO FFI-R personality test. RESULTS: The study included 41 women aged between 18 and 52 years. Vocal intensity and fundamental frequency increased significantly with the introduction of the constraints (P<0.05), intensity passing from 75.5dB to 81.8dB and frequency from 249.4Hz to 335.8Hz. No correlations were found between these changes and results for the various personality traits. CONCLUSIONS: This ecological protocol enables the impact of both physical and emotional obstacles to communication to be studied. No correlations between vocal effort and personality traits emerged. A larger-scale study would be necessary to analyze the continuum between vocal effort and vocal forcing, to improve speech therapy for dysfunctional dysphonia.


Subject(s)
Communication Barriers , Personality , Phonation/physiology , Voice/physiology , Adult , Communication , Competitive Behavior , Female , Games, Experimental , Healthy Volunteers , Humans , Middle Aged , Pilot Projects , Posture , Stress, Psychological/physiopathology , Time , Young Adult
16.
Rev Laryngol Otol Rhinol (Bord) ; 129(4-5): 267-71, 2008.
Article in French | MEDLINE | ID: mdl-19408508

ABSTRACT

UNLABELLED: The antro-choanal polyp is a rather common pathology in children. OBJECTIVE: To discuss the diagnostic modalities, the risk factors, the differential diagnoses and treatment options. MATERIAL AND METHODS: This study was performed in an ENT department of a 3rd referal center Fifteen patients, 12 males and 3 females (8 to 16 year old), were treated for an antro-choanal polyp (Killian's polyp) between 1997 and 2007. RESULTS: All patients presented a nasal obstruction. Other signs of discovery were a rhinorrhea, a maxillary pain or a pharyngeal mass. Two patients presented a recurrence after a surgery in another center Atopy did not seem to be a risk factor. The imaging evaluation showed a tissular process developed in the maxillary sinus and extending through the maxillary ostium, or an accessory ostium, toward the nose. All patients were treated by intranasal endoscopic surgery. The middle meatal antrostomy was systematic, associated with a inferior antrostomy in 3 cases, with an anterior ethmoidectomy in one case and with a vestibular approach (Caldwell-Luc procedure) in 4 cases. Two patients presented a recurrence which necessited a new surgery. CONCLUSION: The antro-choanal polyp must be suspected in front of nasal obstruction in children. The imaging evaluation eliminates the main differential diagnoses. The endo-nasal removal seems to be the best procedure.


Subject(s)
Nasopharyngeal Neoplasms , Nasopharynx , Polyps , Adolescent , Child , Female , Humans , Male , Nasopharyngeal Neoplasms/diagnosis , Nasopharyngeal Neoplasms/surgery , Polyps/diagnosis , Polyps/surgery , Retrospective Studies
17.
Rev Laryngol Otol Rhinol (Bord) ; 128(1-2): 77-9, 2007.
Article in French | MEDLINE | ID: mdl-17633672

ABSTRACT

UNLABELLED: Pneumosinus dilatans is a rare disease that most commonly occurs in young men. It is characterized by an hyperpneumatization of sinus cavities. Its etiopathogenis remains unclear. The bony and mucosal structures are normal and there is no sinus disorders associated with. Most of patients with pneumosinus dilatans present with a cosmetic complaint. CASE REPORT: We report a new surgical technique performed in a young male with bilateral frontal pneumosinus dilatans. A Bi-coronal incision makes it possible to largely expose the anterior wall of the frontal sinus. This wall is then weakened by drilling which should not be transfixiant. A soft impaction of the weakened wall of the sinus, by avoiding any effraction of the sinusal mucous membrane allows a reduction in volume of the frontal sinus with disappearance of the sus-orbital tumefaction. Cosmetic and functional outcomes, 18 months after surgery are good and stable. CONCLUSION: This technique of impaction, without sinusal bone window nor osteosynthesis or bone grafting, preserves the integrity of the sinusal mucous membrane while guaranteeing a good cosmetic result.


Subject(s)
Air , Frontal Sinus/abnormalities , Frontal Sinus/surgery , Adult , Dilatation, Pathologic , Humans , Male , Mucus
18.
Rev Med Interne ; 38(10): 700-703, 2017 Oct.
Article in French | MEDLINE | ID: mdl-28320544

ABSTRACT

INTRODUCTION: Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) is a syndrome that combines dermatological, articular and osseous inflammatory manifestations. Bilateral laryngeal immobility relative to cricoarytenoid joint origin is very uncommon. This article presents a case of bilateral cricoarytenoid joint ankylosis in a SAPHO syndrome context. CASE REPORT: A 53-year-old patient presenting with a two year history of intermittent bouts of dyspnea. A SAPHO syndrome was discussed on repeated thoracic CT-scan. The link between dyspnea and SAPHO syndrome had not been made immediately given the absence of any known anteriority. However, having ruled out other etiologies and after having had to perform a tracheotomy due a worsening of the respiratory condition, this diagnosis was considered. Treatment by corticosteroids and infliximab permitted a clinical improvement of the patient. CONCLUSION: This clinical case report should increase awareness of possible cricoarytenoid joint involvement in SAPHO.


Subject(s)
Acquired Hyperostosis Syndrome/complications , Dyspnea/etiology , Laryngeal Diseases/etiology , Larynx/pathology , Acquired Hyperostosis Syndrome/diagnosis , Acquired Hyperostosis Syndrome/pathology , Dyspnea/diagnosis , Dyspnea/pathology , Humans , Laryngeal Diseases/diagnosis , Laryngeal Diseases/pathology , Male , Middle Aged
19.
Ann Cardiol Angeiol (Paris) ; 54(2): 68-73, 2005 Mar.
Article in French | MEDLINE | ID: mdl-15828460

ABSTRACT

UNLABELLED: The GRACE registry provides the opportunity to analyse management of acute coronary syndromes in the real word and the impact of hospital characteristics. In this setting, we compare the activity of a new coronary intensive care unit with regional data. METHODS: From January 2000 to December 2003, 376 eligible patients were involved (22% of regional inclusion). GRACE standard diagnosis were the following, for our centrer (for the cluster): ST elevation myocardial infarction 28% (37%), non-ST elevation myocardial infarction 32% (31%), unstable angina 33% (24%). Demographic characteristics were similar with a median age of 64 (vs 66) and a large majority of male (74 vs 81%). Medical history and cardiovascular risk factors were comparable. Predictors of hospital mortality were observed at the same rate: cardiogenic shock (3 vs 3%), congestive heart failure > Killip 2 (4 vs 4%), left ventricular ejection fraction (LVEF) lower than 40% (17 vs 16%), recurrent ischemic symptoms (8 vs 8%). Coronary artery bypass grafts were required in 5% (vs 2%). RESULTS: Drugs prescription rates were similar: aspirin at admission (95%) and at discharge (95%), betablocker at admission (70%) and at discharge (85%), statin at admission (< 30% in 2000, > 60% in 2003) and at discharge (< 60% in 2000 and > 80% in 2003), ticlopidin-clopidogrel at admission (< 20% in 2000 and > 40% in 2003), ACE inhibitor for LVEF < 40%, intravenous GPIIblIIa, and low molecular weight heparin (90%). Cardiac catheterisation (90%) and percutaneous coronary interventions (80%) were performed at the same rates in our center and in the cluster. Hospital death was similar (2 vs 4%). Discharge status was home for a large majority of patients (63 vs 76%). The median length of stay was five days and shorter than three days for patients with unstable angina. CONCLUSION: Based on GRACE registry data, the present evaluation revealed that our new center offered evidence-based medical and interventional therapy in patients with acute coronary syndromes at the same level than experienced institutions with similar results for hospital death and length of stay.


Subject(s)
Angina, Unstable/therapy , Coronary Care Units , Electrocardiography , Evidence-Based Medicine , Myocardial Infarction/therapy , Registries , Aged , Angina, Unstable/complications , Angina, Unstable/diagnosis , Angina, Unstable/drug therapy , Angina, Unstable/mortality , Angioplasty, Balloon, Coronary , Female , France , Hospital Mortality , Hospitals, University , Humans , Length of Stay , Male , Middle Aged , Myocardial Infarction/complications , Myocardial Infarction/diagnosis , Myocardial Infarction/drug therapy , Myocardial Infarction/mortality , Prognosis , Risk Factors , Syndrome
20.
Int J Oral Maxillofac Surg ; 44(6): 705-9, 2015 Jun.
Article in English | MEDLINE | ID: mdl-25697064

ABSTRACT

The aim of this study was to analyze the causal mechanisms of severe swallowing disorders after the treatment of oropharyngeal cancer. Twenty-six patients with severe swallowing disorders at ≥12 months after treatment for oropharyngeal cancer were analyzed retrospectively using videofluoroscopy. Fourteen patients (54%) had been treated with surgery (±postoperative radiotherapy), while 12 patients (46%) had been treated with (chemo)radiotherapy. Videofluoroscopy analysis showed a localized alteration in the surgical excision area resulting in impaired tongue root retraction in the surgical group (P=0.012), while general impairment of the pharyngeal, laryngeal, and upper oesophagus sphincter was found in the non-surgical group. Aspirations in the surgical group most often occurred after swallowing, while in the non-surgical group, they occurred during and after swallowing (P=0.039). This analysis by videofluoroscopy provides important insights into the mechanisms giving rise to swallowing disorders after the treatment of oropharyngeal cancer.


Subject(s)
Deglutition Disorders/diagnostic imaging , Deglutition Disorders/etiology , Oropharyngeal Neoplasms/radiotherapy , Oropharyngeal Neoplasms/surgery , Adult , Aged , Aged, 80 and over , Female , Fluoroscopy , Humans , Male , Middle Aged , Neck Dissection , Neoplasm Staging , Oropharyngeal Neoplasms/pathology , Quality of Life , Retrospective Studies , Surgical Flaps , Video Recording
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