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1.
Conjugation Site Influences Antibody-Conjugated Drug PK Assays: Case Studies for Disulfide-Linked, Self-Immolating Next-Generation Antibody Drug Conjugates.
Anal Chem
; 92(18): 12168-12175, 2020 09 15.
Article
in English
| MEDLINE | ID: mdl-32786429
2.
Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti-Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats.
Drug Metab Dispos
; 48(11): 1161-1168, 2020 11.
Article
in English
| MEDLINE | ID: mdl-32839277
3.
Antibody-Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo.
Bioconjug Chem
; 30(5): 1356-1370, 2019 05 15.
Article
in English
| MEDLINE | ID: mdl-30966735
4.
Pathway connectivity and signaling coordination in the yeast stress-activated signaling network.
Mol Syst Biol
; 10: 759, 2014 Nov 19.
Article
in English
| MEDLINE | ID: mdl-25411400
5.
Gas-phase purification enables accurate, multiplexed proteome quantification with isobaric tagging.
Nat Methods
; 8(11): 933-5, 2011 Oct 02.
Article
in English
| MEDLINE | ID: mdl-21963608
6.
The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results.
Nat Commun
; 15(1): 466, 2024 Jan 11.
Article
in English
| MEDLINE | ID: mdl-38212321
7.
Development of a semi-automated MHC-associated peptide proteomics (MAPPs) method using streptavidin bead-based immunoaffinity capture and nano LC-MS/MS to support immunogenicity risk assessment in drug development.
Front Immunol
; 14: 1295285, 2023.
Article
in English
| MEDLINE | ID: mdl-38022649
8.
Infrared multiphoton dissociation for quantitative shotgun proteomics.
Anal Chem
; 84(10): 4513-9, 2012 May 15.
Article
in English
| MEDLINE | ID: mdl-22480380
9.
A dynamic model of proteome changes reveals new roles for transcript alteration in yeast.
Mol Syst Biol
; 7: 514, 2011 Jul 19.
Article
in English
| MEDLINE | ID: mdl-21772262
10.
COMPASS: a suite of pre- and post-search proteomics software tools for OMSSA.
Proteomics
; 11(6): 1064-74, 2011 Mar.
Article
in English
| MEDLINE | ID: mdl-21298793
11.
Preclinical Characterization of the Distribution, Catabolism, and Elimination of a Polatuzumab Vedotin-Piiq (POLIVY®) Antibody-Drug Conjugate in Sprague Dawley Rats.
J Clin Med
; 10(6)2021 Mar 23.
Article
in English
| MEDLINE | ID: mdl-33806916
12.
Analysis of tandem mass spectra by FTMS for improved large-scale proteomics with superior protein quantification.
Anal Chem
; 82(1): 316-22, 2010 Jan 01.
Article
in English
| MEDLINE | ID: mdl-19938823
13.
Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry.
J Am Chem Soc
; 131(34): 12258-64, 2009 Sep 02.
Article
in English
| MEDLINE | ID: mdl-19663480
14.
Preclinical pharmacokinetics and pharmacodynamics of DCLL9718A: An antibody-drug conjugate for the treatment of acute myeloid leukemia.
MAbs
; 10(8): 1312-1321, 2018.
Article
in English
| MEDLINE | ID: mdl-30183491
15.
Characterization and diagnostic value of amino acid side chain neutral losses following electron-transfer dissociation.
J Am Soc Mass Spectrom
; 22(2): 255-64, 2011 Feb.
Article
in English
| MEDLINE | ID: mdl-21472585
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