Search details
1.
Targeted mRNA Therapy for Ornithine Transcarbamylase Deficiency.
Mol Ther
; 26(3): 801-813, 2018 03 07.
Article
in English
| MEDLINE | ID: mdl-29433939
2.
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature
; 463(7280): 501-6, 2010 Jan 28.
Article
in English
| MEDLINE | ID: mdl-20072125
3.
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Proc Natl Acad Sci U S A
; 110(50): 20224-9, 2013 Dec 10.
Article
in English
| MEDLINE | ID: mdl-24277854
4.
Smad7-induced beta-catenin degradation alters epidermal appendage development.
Dev Cell
; 11(3): 301-12, 2006 Sep.
Article
in English
| MEDLINE | ID: mdl-16950122
5.
Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.
J Clin Invest
; 115(7): 1714-23, 2005 Jul.
Article
in English
| MEDLINE | ID: mdl-15937546
6.
Elevation of transforming growth factor beta (TGFbeta) and its downstream mediators in subcutaneous foreign body capsule tissue.
J Biomed Mater Res A
; 82(2): 498-508, 2007 Aug.
Article
in English
| MEDLINE | ID: mdl-17295253
7.
Roles of TGFbeta signaling in epidermal/appendage development.
Cytokine Growth Factor Rev
; 14(2): 99-111, 2003 Apr.
Article
in English
| MEDLINE | ID: mdl-12651222
8.
Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis.
Cancer Res
; 64(21): 7836-45, 2004 Nov 01.
Article
in English
| MEDLINE | ID: mdl-15520189
9.
Overexpression of transforming growth factor beta1 in head and neck epithelia results in inflammation, angiogenesis, and epithelial hyperproliferation.
Cancer Res
; 64(13): 4405-10, 2004 Jul 01.
Article
in English
| MEDLINE | ID: mdl-15231647
10.
Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials.
J Med Chem
; 56(14): 5675-90, 2013 Jul 25.
Article
in English
| MEDLINE | ID: mdl-23742252
11.
Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.
J Invest Dermatol
; 131(2): 302-10, 2011 Feb.
Article
in English
| MEDLINE | ID: mdl-20962855
12.
A role for TGFbeta signaling in the pathogenesis of psoriasis.
J Invest Dermatol
; 130(2): 371-7, 2010 Feb.
Article
in English
| MEDLINE | ID: mdl-19710682
13.
The role of Smads in skin development.
J Invest Dermatol
; 128(4): 783-90, 2008 Apr.
Article
in English
| MEDLINE | ID: mdl-18337711
14.
Increased expression of Interleukin-13 and connective tissue growth factor, and their potential roles during foreign body encapsulation of subcutaneous implants.
J Biomater Sci Polym Ed
; 19(8): 1065-72, 2008.
Article
in English
| MEDLINE | ID: mdl-18644231
15.
Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2.
Nat Immunol
; 8(5): 504-13, 2007 May.
Article
in English
| MEDLINE | ID: mdl-17384642
16.
Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma.
Genes Dev
; 20(10): 1331-42, 2006 May 15.
Article
in English
| MEDLINE | ID: mdl-16702406
17.
Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.
J Am Soc Nephrol
; 16(5): 1371-83, 2005 May.
Article
in English
| MEDLINE | ID: mdl-15788474
18.
Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder.
EMBO J
; 23(8): 1770-81, 2004 Apr 21.
Article
in English
| MEDLINE | ID: mdl-15057277
19.
Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis.
Genesis
; 39(1): 10-25, 2004 May.
Article
in English
| MEDLINE | ID: mdl-15124223
20.
Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues.
EMBO J
; 21(11): 2580-90, 2002 Jun 03.
Article
in English
| MEDLINE | ID: mdl-12032071
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