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1.
Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11ß-HSD1 using a scaffold-hopping approach.
Bioorg Med Chem Lett
; 69: 128782, 2022 08 01.
Article
in English
| MEDLINE | ID: mdl-35537608
2.
Dynamic changes in chemical compositions and anti-acetylcholinesterase activity associated with steaming process of stem-leaf saponins of Panax notoginseng.
Biomed Chromatogr
; 35(6): e5077, 2021 Jun.
Article
in English
| MEDLINE | ID: mdl-33475178
3.
Pharmacokinetic studies of ginsenosides Rk1 and Rg5 in rats by UFLC-MS/MS.
Biomed Chromatogr
; 35(8): e5108, 2021 Aug.
Article
in English
| MEDLINE | ID: mdl-33650162
4.
Identification and characterization of forced degradation products and stability-indicating assay for notoginsenosidefc by using UHPLC-Q-TOF-MS and UHPLC-MS/MS: Insights into stability profile and degradation pathways.
J Sep Sci
; 42(8): 1550-1563, 2019 Apr.
Article
in English
| MEDLINE | ID: mdl-30768757
5.
Betaine alleviates spermatogenic cells apoptosis of oligoasthenozoospermia rat model by up-regulating methyltransferases and affecting DNA methylation.
Phytomedicine
; 129: 155713, 2024 Jul.
Article
in English
| MEDLINE | ID: mdl-38735196
6.
Solitary fibrous tumor of the central nervous system invading and penetrating the skull: A case report.
Oncol Lett
; 25(2): 81, 2023 Feb.
Article
in English
| MEDLINE | ID: mdl-36742362
7.
Dopey2 and Pcdh7 orchestrate the development of embryonic neural stem cells/ progenitors in zebrafish.
iScience
; 26(3): 106273, 2023 Mar 17.
Article
in English
| MEDLINE | ID: mdl-36936789
8.
Metabolic profiling and pharmacokinetic studies of sinapine thiocyanate by UHPLC-Q/TOF-MS and UHPLC-MS/MS.
J Pharm Biomed Anal
; 207: 114431, 2022 Jan 05.
Article
in English
| MEDLINE | ID: mdl-34710728
9.
Biotransformation patterns of dictamnine in vitro/in vivo and its relative molecular mechanism of dictamnine-induced acute liver injury in mice.
Environ Toxicol Pharmacol
; 85: 103628, 2021 Jul.
Article
in English
| MEDLINE | ID: mdl-33652109
10.
Metabolites identification and reversible interconversion of chelerythrine and dihydrochelerythrine in vitro/in vivo in rats using ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
J Pharm Biomed Anal
; 189: 113462, 2020 Sep 10.
Article
in English
| MEDLINE | ID: mdl-32659571
11.
[Treatment efficacy of Solitaire stent- and LVIS stent-assisted coil embolization for intracranial wide-neck carotid aneurysm].
Nan Fang Yi Ke Da Xue Xue Bao
; 40(3): 423-426, 2020 Mar 30.
Article
in Zh
| MEDLINE | ID: mdl-32376577
12.
Rapid identification and pharmacokinetic studies of multiple active alkaloids in rat plasma through UPLC-Q-TOF-MS and UPLC-MS/MS after the oral administration of Zanthoxylum nitidum extract.
J Pharm Biomed Anal
; 186: 113232, 2020 Jul 15.
Article
in English
| MEDLINE | ID: mdl-32229392
13.
Spongipyran Synthetic Studies. Total Synthesis of (+)-Spongistatin 2.
Tetrahedron
; 65(33): 6470-6488, 2009 Aug 15.
Article
in English
| MEDLINE | ID: mdl-20161196
14.
Analogous ß-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice.
Front Pharmacol
; 9: 346, 2018.
Article
in English
| MEDLINE | ID: mdl-29755345
15.
Discovery of a potent, selective, and orally active human epidermal growth factor receptor-2 sheddase inhibitor for the treatment of cancer.
J Med Chem
; 50(4): 603-6, 2007 Feb 22.
Article
in English
| MEDLINE | ID: mdl-17256836
16.
Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells.
Cancer Biol Ther
; 5(6): 657-64, 2006 Jun.
Article
in English
| MEDLINE | ID: mdl-16627989
17.
The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2 Financial support was provided by the National Institutes of Health (National Cancer Institute) through Grant CA-70329, a NIH Postdoctoral Fellowship to C.S.B., a Japan Society for Promotion of Science Fellowship to N.M., and a Royal Society Fulbright Fellowship to V.A.D. We also thank the Daiichi Pharmaceutical Co., Ltd, and the Tanabe Seiyaku Co., Ltd for financial support. Finally we thank Dr George T. Furst, Dr. Patrick J. Carroll, and Dr. Rakesh Kohli of the University of Pennsylvania Spectroscopic Service Center for assistance in securing and interpreting high-field NMR spectra, X-ray crystal structures, and mass spectra, respectively.
Angew Chem Int Ed Engl
; 40(1): 196-199, 2001 Jan 05.
Article
in English
| MEDLINE | ID: mdl-11169711
18.
The Spongistatins: Architecturally Complex Natural Products-Part Two: Synthesis of the C(29-51) Subunit, Fragment Assembly, and Final Elaboration to (+)-Spongistatin 2.
Angew Chem Int Ed Engl
; 40(1): 196-199, 2001 Jan 05.
Article
in English
| MEDLINE | ID: mdl-29711943
19.
The Spongistatins: Architecturally Complex Natural Products-Part One: A Formal Synthesis of (+)-Spongistatin 1 by Construction of an Advanced ABCD Fragment Financial support was provided by the National Institutes of Health (National Cancer Institute) through Grant CA-70329, NIH Postdoctoral Fellowships to A.M.B. and W.H.M., a Japan Society for Promotion of Science Fellowship to N.M., and a Royal Society Fulbright Fellowship to V.A.D. We also thank the Daiichi Pharmaceutical Co., Ltd, and the Tanabe Seiyaku Co., Ltd for financial support. Finally we thank Dr. George T. Furst, Dr. Patrick J. Carroll, Dr. Rakesh Kohli, and Mr John Dykins of the University of Pennsylvania Spectroscopic Service Center for assistance in securing and interpreting high-field NMR spectra, X-ray crystal structures, and mass spectra.
Angew Chem Int Ed Engl
; 40(1): 191-195, 2001 Jan 05.
Article
in English
| MEDLINE | ID: mdl-11169710
20.
The Spongistatins: Architecturally Complex Natural Products-Part One: A Formal Synthesis of (+)-Spongistatin 1 by Construction of an Advanced ABCD Fragment.
Angew Chem Int Ed Engl
; 40(1): 191-195, 2001 Jan 05.
Article
in English
| MEDLINE | ID: mdl-29711948