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1.
CSL324, a granulocyte colony-stimulating factor receptor antagonist, blocks neutrophil migration markers that are upregulated in hidradenitis suppurativa.
Br J Dermatol
; 188(5): 636-648, 2023 04 20.
Article
in English
| MEDLINE | ID: mdl-36691791
2.
Activated MLKL attenuates autophagy following its translocation to intracellular membranes.
J Cell Sci
; 132(5)2019 02 28.
Article
in English
| MEDLINE | ID: mdl-30709919
3.
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Proc Natl Acad Sci U S A
; 114(6): E961-E969, 2017 02 07.
Article
in English
| MEDLINE | ID: mdl-28096356
4.
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.
J Biol Chem
; 293(23): 8874-8885, 2018 06 08.
Article
in English
| MEDLINE | ID: mdl-29695504
5.
The molecular relationships between apoptosis, autophagy and necroptosis.
Semin Cell Dev Biol
; 39: 63-9, 2015 Mar.
Article
in English
| MEDLINE | ID: mdl-25736836
6.
Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
Proc Natl Acad Sci U S A
; 111(23): 8512-7, 2014 Jun 10.
Article
in English
| MEDLINE | ID: mdl-24912196
7.
Total synthesis of a biotinylated rocaglate: Selective targeting of the translation factors eIF4AI/II.
Bioorg Med Chem Lett
; 26(2): 262-264, 2016 Jan 15.
Article
in English
| MEDLINE | ID: mdl-26718843
8.
Total synthesis of 2''',5'''-diepisilvestrol and its C1''' epimer: key structure activity relationships at C1''' and C2'''.
J Nat Prod
; 75(8): 1500-4, 2012 Aug 24.
Article
in English
| MEDLINE | ID: mdl-22817615
9.
By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737.
Cell Death Differ
; 26(9): 1766-1781, 2019 09.
Article
in English
| MEDLINE | ID: mdl-30538285
10.
In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose.
Cell Death Differ
; 26(10): 2074-2085, 2019 Oct.
Article
in English
| MEDLINE | ID: mdl-30770875
11.
Cross-talk between protein synthesis, energy metabolism and autophagy in cancer.
Curr Opin Genet Dev
; 48: 104-111, 2018 02.
Article
in English
| MEDLINE | ID: mdl-29179096
12.
Simultaneous Detection of Cellular Viability and Interleukin-1ß Secretion from Single Cells by ELISpot.
Methods Mol Biol
; 1714: 229-236, 2018.
Article
in English
| MEDLINE | ID: mdl-29177866
13.
Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.
Cell Death Differ
; 25(4): 784-796, 2018 03.
Article
in English
| MEDLINE | ID: mdl-29229994
14.
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1ß Activation.
Cell Rep
; 25(9): 2339-2353.e4, 2018 11 27.
Article
in English
| MEDLINE | ID: mdl-30485804
15.
DNA repair processes are critical mediators of p53-dependent tumor suppression.
Nat Med
; 24(7): 947-953, 2018 07.
Article
in English
| MEDLINE | ID: mdl-29892060
16.
BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux.
Autophagy
; 12(7): 1083-93, 2016 07 02.
Article
in English
| MEDLINE | ID: mdl-27172402
17.
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production.
Nat Commun
; 6: 6442, 2015 Mar 17.
Article
in English
| MEDLINE | ID: mdl-25778803
18.
BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy.
Autophagy
; 10(8): 1474-5, 2014 Aug.
Article
in English
| MEDLINE | ID: mdl-24991825
19.
Single-molecule kinetics of the eukaryotic initiation factor 4AI upon RNA unwinding.
Structure
; 22(7): 941-8, 2014 Jul 08.
Article
in English
| MEDLINE | ID: mdl-24909782
20.
Simplified silvestrol analogues with potent cytotoxic activity.
ChemMedChem
; 9(7): 1556-66, 2014 Jul.
Article
in English
| MEDLINE | ID: mdl-24677741