ABSTRACT
Tropical pyomyositis is a disease of skeletal muscle characterized by single or multiple abscesses. The infective organism is most often penicillin-resistant Staphylococcus aureus. Only recently have case reports appeared in the literature from temperate zones; however, this disease is common in the tropics. This report reviews the literature and describes a child from rural North Carolina in whom tropical pyomyositis developed after incision and drainage of a furuncle.
Subject(s)
Abscess/diagnostic imaging , Myositis/diagnostic imaging , Abscess/drug therapy , Adult , Humans , Male , Methicillin/therapeutic use , Microbial Sensitivity Tests , Myositis/drug therapy , Radiography , Staphylococcal Infections/diagnostic imaging , Vancomycin/therapeutic useSubject(s)
Affective Symptoms/drug therapy , Central Nervous System Diseases/chemically induced , Infant, Newborn, Diseases/chemically induced , Lithium/poisoning , Pregnancy Complications/drug therapy , Adult , Coma/chemically induced , Cyanosis/chemically induced , Female , Humans , Infant , Infant, Newborn , Lithium/metabolism , Maternal-Fetal Exchange , Muscle Cramp/chemically induced , Muscle Tonus , PregnancyABSTRACT
We report two cases of Lyme disease in North Carolina, further expanding the distribution of known sporadic cases of this predominantly northeastern problem in southern states. Physicians in areas where Lyme disease has traditionally not been recognized should be alerted to its characteristic rash (erythema chronicum migrans), tick vector (Ixodes species), possible severe manifestations (neurologic, arthritic, and cardiac), and response to appropriate antibiotic therapy (penicillin or tetracycline).
Subject(s)
Arthritis, Infectious/epidemiology , Adolescent , Arachnid Vectors , Arthritis, Infectious/diagnosis , Arthritis, Infectious/drug therapy , Female , Humans , Male , Middle Aged , North Carolina , Tetracycline/therapeutic use , TicksABSTRACT
Seventy-six children (aged 17-19 months) received 10 micrograms of Haemophilus influenzae type b polyribosyl-ribitol phosphate (PRP) vaccine, diluted with either phosphate-buffered saline (PBS) or diphtheria-tetanus-pertussis (DTP) vaccine, in a single-blind randomized trial. There were few side effects when PRP was administered alone. Before vaccination 37 of 76 children (49%) had non-protective antibody levels (less than 0.15 micrograms/mL); 26 of these 37 (70%) achieved antibody levels of greater than 0.15 micrograms/mL 1 month after vaccination. Before vaccination 16 of 76 (21%) had antibody levels of greater than 1.0 micrograms/mL; 1 month after vaccination 39 of 76 children (51%) achieved levels of greater than 1.0 micrograms/mL. Of 12 infants who had antibody levels less than 0.15 micrograms/mL 1 month after immunization, 10 had protective levels 18 months later. Administration of PRP mixed with DTP did not affect antibody response to PRP. The potential use and limitations of PRP vaccine are discussed.