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1.

Effect of the P-Selectin Inhibitor Crizanlizumab on Survival Free of Organ Support in Patients Hospitalized for COVID-19: A Randomized Controlled Trial.

Solomon, Scott D; Lowenstein, Charles J; Bhatt, Ankeet S; Peikert, Alexander; Vardeny, Orly; Kosiborod, Mikhail N; Berger, Jeffrey S; Reynolds, Harmony R; Mavromichalis, Stephanie; Barytol, Anya; Althouse, Andrew D; Luther, James F; Leifer, Eric S; Kindzelski, Andrei L; Cushman, Mary; Gong, Michelle N; Kornblith, Lucy Z; Khatri, Pooja; Kim, Keri S; Baumann Kreuziger, Lisa; Wahid, Lana; Kirwan, Bridget-Anne; Geraci, Mark W; Neal, Matthew D; Hochman, Judith S.

Circulation ; 148(5): 381-390, 2023 08.

Article in English | MEDLINE | ID: mdl-37356038

2.

Dyslipidemia.

Arvanitis, Marios; Lowenstein, Charles J.

Ann Intern Med ; 176(6): ITC81-ITC96, 2023 06.

Article in English | MEDLINE | ID: mdl-37307585

3.

Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19 Acute Respiratory Distress Syndrome.

Metkus, Thomas S; Sokoll, Lori J; Barth, Andreas S; Czarny, Matthew J; Hays, Allison G; Lowenstein, Charles J; Michos, Erin D; Nolley, Eric P; Post, Wendy S; Resar, Jon R; Thiemann, David R; Trost, Jeffrey C; Hasan, Rani K.

Circulation ; 143(6): 553-565, 2021 02 09.

Article in English | MEDLINE | ID: mdl-33186055

4.

Estrogen activates endothelial exocytosis.

Kim, Christine S; Yea, Kyungmoo; Morrell, Craig N; Jeong, Youngtae; Lowenstein, Charles J.

Biochem Biophys Res Commun ; 558: 29-35, 2021 06 18.

Article in English | MEDLINE | ID: mdl-33895548

5.

Metabolism reprogrammed by the nitric oxide signalling molecule.

Lowenstein, Charles J.

Nature ; 565(7737): 33-34, 2019 01.

Article in English | MEDLINE | ID: mdl-30573784

6.

Acetylcholine Inhibits Platelet Activation.

Bennett, John A; Ture, Sara K; Schmidt, Rachel A; Mastrangelo, Michael A; Cameron, Scott J; Terry, Lara E; Yule, David I; Morrell, Craig N; Lowenstein, Charles J.

J Pharmacol Exp Ther ; 369(2): 182-187, 2019 05.

Article in English | MEDLINE | ID: mdl-30765424

7.

Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.

Zhu, Qiuyu Martin; Ko, Kyung Ae; Ture, Sara; Mastrangelo, Michael A; Chen, Ming-Huei; Johnson, Andrew D; O'Donnell, Christopher J; Morrell, Craig N; Miano, Joseph M; Lowenstein, Charles J.

Arterioscler Thromb Vasc Biol ; 37(2): 264-270, 2017 Feb.

Article in English | MEDLINE | ID: mdl-28062498

8.

A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.

Miano, Joseph M; Zhu, Qiuyu Martin; Lowenstein, Charles J.

Arterioscler Thromb Vasc Biol ; 36(6): 1058-75, 2016 06.

Article in English | MEDLINE | ID: mdl-27102963

9.

Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients.

Croft, Daniel P; Cameron, Scott J; Morrell, Craig N; Lowenstein, Charles J; Ling, Frederick; Zareba, Wojciech; Hopke, Philip K; Utell, Mark J; Thurston, Sally W; Thevenet-Morrison, Kelly; Evans, Kristin A; Chalupa, David; Rich, David Q.

Environ Res ; 154: 352-361, 2017 04.

Article in English | MEDLINE | ID: mdl-28167447

10.

Severe COVID-19 Is a Microvascular Disease.

Lowenstein, Charles J; Solomon, Scott D.

Circulation ; 142(17): 1609-1611, 2020 10 27.

Article in English | MEDLINE | ID: mdl-32877231

11.

Sarnoff Cardiovascular Research Foundation: Inspiring the Physician-Scientists of Tomorrow.

Lowenstein, Charles J; Weisfeldt, Myron L; Mitchell, Jere H.

Circulation ; 138(6): 554-556, 2018 08 07.

Article in English | MEDLINE | ID: mdl-30354611

12.

VAMP-3 mediates platelet endocytosis.

Lowenstein, Charles J.

Blood ; 130(26): 2816-2818, 2017 12 28.

Article in English | MEDLINE | ID: mdl-29284612

13.

Enhanced assay of endothelial exocytosis using extracellular matrix components.

LoMonaco, Michael B; Lowenstein, Charles J.

Anal Biochem ; 452: 19-24, 2014 May 01.

Article in English | MEDLINE | ID: mdl-24561025

14.

Genome-Wide Investigation of Exogenous Female Hormones, Genetic Variation, and Venous Thromboembolism Risk.

Hasser, Emily K; Brody, Jennifer A; Bartz, Traci M; Thibord, Florian; Li-Gao, Ruifang; Kauko, Anni; Wiggins, Kerri L; Teder-Laving, Maris; Kim, Jihye; Munsch, Gaëlle; Haile, Helen G; Deleuze, Jean-Francois; van Hylckama Vlieg, Astrid; Wolberg, Alisa S; Boland, Anne; Morange, Pierre-Emmanuel; Kraft, Peter; Lowenstein, Charles J; Emmerich, Joseph; Sitlani, Colleen M; Suchon, Pierre; Rosendaal, Frits R; Niiranen, Teemu; Kabrhel, Christopher; Trégouët, David-Alexandre; Smith, Nicholas L.

J Thromb Haemost ; 2024 May 21.

Article in English | MEDLINE | ID: mdl-38782299

15.

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis.

Yamakuchi, Munekazu; Lotterman, Craig D; Bao, Clare; Hruban, Ralph H; Karim, Baktiar; Mendell, Joshua T; Huso, David; Lowenstein, Charles J.

Proc Natl Acad Sci U S A ; 107(14): 6334-9, 2010 Apr 06.

Article in English | MEDLINE | ID: mdl-20308559

16.

High risk oral contraceptive hormones do not directly enhance endothelial cell procoagulant activity in vitro.

Bouck, Emma G; Arvanitis, Marios; Osburn, William O; Sang, Yaqiu; Reventun, Paula; Ahmadzia, Homa K; Smith, Nicholas L; Lowenstein, Charles J; Wolberg, Alisa S.

PLoS One ; 18(4): e0284333, 2023.

Article in English | MEDLINE | ID: mdl-37075041

17.

Cardiac pericytes mediate the remodeling response to myocardial infarction.

Quijada, Pearl; Park, Shuin; Zhao, Peng; Kolluri, Kamal Ss; Wong, David; Shih, Kevin D; Fang, Kai; Pezhouman, Arash; Wang, Lingjun; Daraei, Ali; Tran, Matthew D; Rathbun, Elle M; Burgos Villar, Kimberly N; Garcia-Hernandez, Maria L; Pham, Thanh Td; Lowenstein, Charles J; Iruela-Arispe, M Luisa; Carmichael, S Thomas; Small, Eric M; Ardehali, Reza.

J Clin Invest ; 133(10)2023 05 15.

Article in English | MEDLINE | ID: mdl-37183820

18.

Thioredoxin increases exocytosis by denitrosylating N-ethylmaleimide-sensitive factor.

Ito, Takashi; Yamakuchi, Munekazu; Lowenstein, Charles J.

J Biol Chem ; 286(13): 11179-84, 2011 Apr 01.

Article in English | MEDLINE | ID: mdl-21324905

19.

Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.

Goel, Aditya; Su, Baogen; Flavahan, Sheila; Lowenstein, Charles J; Berkowitz, Dan E; Flavahan, Nicholas A.

Circ Res ; 107(2): 242-51, 2010 Jul 23.

Article in English | MEDLINE | ID: mdl-20522806

20.

Aldosterone activates endothelial exocytosis.

Jeong, Youngtae; Chaupin, Damian F; Matsushita, Kenji; Yamakuchi, Munekazu; Cameron, Scott J; Morrell, Craig N; Lowenstein, Charles J.

Proc Natl Acad Sci U S A ; 106(10): 3782-7, 2009 Mar 10.

Article in English | MEDLINE | ID: mdl-19223584

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