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Results 1 - 20 de 35

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1.

BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes.

Bai, Long; Li, Peng; Xiang, Yu; Jiao, Xiaofei; Chen, Jiyuan; Song, Licun; Liang, Zhongyang; Liu, Yidan; Zhu, Yimin; Lu, Lin-Yu.

Proc Natl Acad Sci U S A ; 121(19): e2401386121, 2024 May 07.

Article in English | MEDLINE | ID: mdl-38696471

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11087798
https://dx.doi.org/10.1073/pnas.2401386121

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2.

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.

Li, Mo; Lu, Lin-Yu; Yang, Chao-Yie; Wang, Shaomeng; Yu, Xiaochun.

Genes Dev ; 27(16): 1752-68, 2013 Aug 15.

Article in English | MEDLINE | ID: mdl-23964092

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759693
https://dx.doi.org/10.1101/gad.226357.113

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3.

Defective piRNA Processing and Azoospermia.

Li, Lejun; Tan, Yue-Qiu; Lu, Lin-Yu.

N Engl J Med ; 386(17): 1675-1676, 2022 04 28.

Article in English | MEDLINE | ID: mdl-35476666

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4.

Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader.

Liu, Yidan; Zhang, Bin; Kuang, Henry; Korakavi, Gautam; Lu, Lin-Yu; Yu, Xiaochun.

J Biol Chem ; 291(26): 13679-88, 2016 Jun 24.

Article in English | MEDLINE | ID: mdl-27129234

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919451
https://dx.doi.org/10.1074/jbc.M116.717314

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5.

Topoisomerase II regulates the maintenance of DNA methylation.

Lu, Lin-Yu; Kuang, Henry; Korakavi, Gautam; Yu, Xiaochun.

J Biol Chem ; 290(2): 851-60, 2015 Jan 09.

Article in English | MEDLINE | ID: mdl-25451918

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294507
https://dx.doi.org/10.1074/jbc.M114.611509

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6.

MRE11 is essential for the long-term viability of undifferentiated spermatogonia.

Tang, Zhenghui; Liang, Zhongyang; Zhang, Bin; Xu, Xiaohui; Li, Peng; Li, Lejun; Lu, Lin-Yu; Liu, Yidan.

Cell Prolif ; : e13685, 2024 Jun 18.

Article in English | MEDLINE | ID: mdl-38894566

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7.

Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood.

Lu, Song; Lu, Lin-Yu; Liu, Meng-Fei; Yuan, Qiu-Ju; Sham, Mai-Har; Guan, Xin-Yuan; Huang, Jian-Dong.

Neurobiol Dis ; 45(1): 219-33, 2012 Jan.

Article in English | MEDLINE | ID: mdl-21871565

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8.

Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia.

Xie, Chunbo; Wang, Weili; Tu, Chaofeng; Meng, Lanlan; Lu, Guangxiu; Lin, Ge; Lu, Lin-Yu; Tan, Yue-Qiu.

Hum Reprod Update ; 28(6): 763-797, 2022 11 02.

Article in English | MEDLINE | ID: mdl-35613017

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9.

BRCA1 and homologous recombination: implications from mouse embryonic development.

Liu, Yidan; Lu, Lin-Yu.

Cell Biosci ; 10: 49, 2020.

Article in English | MEDLINE | ID: mdl-32257107

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106644
https://dx.doi.org/10.1186/s13578-020-00412-4

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10.

NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis.

Zhang, Bin; Tang, Zhenghui; Li, Lejun; Lu, Lin-Yu.

Cell Death Differ ; 27(7): 2176-2190, 2020 07.

Article in English | MEDLINE | ID: mdl-31965061

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308329
https://dx.doi.org/10.1038/s41418-020-0493-4

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11.

The RNF20/40 complex regulates p53-dependent gene transcription and mRNA splicing.

Wu, Chen; Cui, Yaqi; Liu, Xiuhua; Zhang, Feng; Lu, Lin-Yu; Yu, Xiaochun.

J Mol Cell Biol ; 12(2): 113-124, 2020 02 20.

Article in English | MEDLINE | ID: mdl-31152661

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109600
https://dx.doi.org/10.1093/jmcb/mjz045

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12.

Aberrantly expressed HORMAD1 disrupts nuclear localization of MCM8-MCM9 complex and compromises DNA mismatch repair in cancer cells.

Liu, Kang; Wang, Yifan; Zhu, Quanfeng; Li, Peng; Chen, Jiyuan; Tang, Zhenghui; Shen, Yuanming; Cheng, Xiaodong; Lu, Lin-Yu; Liu, Yidan.

Cell Death Dis ; 11(7): 519, 2020 07 09.

Article in English | MEDLINE | ID: mdl-32647118

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347845
https://dx.doi.org/10.1038/s41419-020-2736-1

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13.

53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice.

Chen, Jiyuan; Li, Peng; Song, Licun; Bai, Long; Huen, Michael S Y; Liu, Yidan; Lu, Lin-Yu.

Cell Death Differ ; 27(9): 2552-2567, 2020 09.

Article in English | MEDLINE | ID: mdl-32139898

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429965
https://dx.doi.org/10.1038/s41418-020-0521-4

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14.

Highly efficient deletion method for the engineering of plasmid DNA with single-stranded oligonucleotides.

Lu, Lin-Yu; Huen, Michael S Y; Tai, Andrew Chi-Pang; Liu, De-Pei; Cheah, Kathryn S E; Huang, Jian-Dong.

Biotechniques ; 44(2): 217-20, 222, 224, 2008 Feb.

Article in English | MEDLINE | ID: mdl-18330349

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15.

The involvement of replication in single stranded oligonucleotide-mediated gene repair.

Huen, Michael S Y; Li, Xin-tian; Lu, Lin-Yu; Watt, Rory M; Liu, De-Pei; Huang, Jian-Dong.

Nucleic Acids Res ; 34(21): 6183-94, 2006.

Article in English | MEDLINE | ID: mdl-17088285

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16.

UHRF2 regulates local 5-methylcytosine and suppresses spontaneous seizures.

Liu, Yidan; Zhang, Bin; Meng, Xiaoyu; Korn, Matthew J; Parent, Jack M; Lu, Lin-Yu; Yu, Xiaochun.

Epigenetics ; 12(7): 551-560, 2017 07 03.

Article in English | MEDLINE | ID: mdl-28402695

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687333
https://dx.doi.org/10.1080/15592294.2017.1314423

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17.

The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus.

Tanner, Julian A; Zheng, Bo-Jian; Zhou, Jie; Watt, Rory M; Jiang, Jie-Qing; Wong, Kin-Ling; Lin, Yong-Ping; Lu, Lin-Yu; He, Ming-Liang; Kung, Hsiang-Fu; Kesel, Andreas J; Huang, Jian-Dong.

Chem Biol ; 12(3): 303-11, 2005 Mar.

Article in English | MEDLINE | ID: mdl-15797214

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18.

Identification of factors influencing strand bias in oligonucleotide-mediated recombination in Escherichia coli.

Li, Xin-tian; Costantino, Nina; Lu, Lin-yu; Liu, De-pei; Watt, Rory M; Cheah, Kathryn S E; Court, Donald L; Huang, Jian-Dong.

Nucleic Acids Res ; 31(22): 6674-87, 2003 Nov 15.

Article in English | MEDLINE | ID: mdl-14602928

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19.

Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway.

Han, Deqiang; Liang, Junbo; Lu, Yalan; Xu, Longchang; Miao, Shiying; Lu, Lin-Yu; Song, Wei; Wang, Linfang.

PLoS One ; 11(5): e0155476, 2016.

Article in English | MEDLINE | ID: mdl-27195665

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873259
https://dx.doi.org/10.1371/journal.pone.0155476

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20.

CHFR is important for the survival of male premeiotic germ cells.

Lu, Lin-Yu; Yu, Xiaochun.

Cell Cycle ; 14(21): 3454-60, 2015.

Article in English | MEDLINE | ID: mdl-26566864

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825563
https://dx.doi.org/10.1080/15384101.2015.1093701

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