Search details
1.
BET inhibitor resistance emerges from leukaemia stem cells.
Nature
; 525(7570): 538-42, 2015 Sep 24.
Article
in English
| MEDLINE | ID: mdl-26367796
2.
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Nature
; 478(7370): 529-33, 2011 Oct 02.
Article
in English
| MEDLINE | ID: mdl-21964340
3.
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors.
Bioorg Med Chem Lett
; 26(19): 4606-4612, 2016 10 01.
Article
in English
| MEDLINE | ID: mdl-27578246
4.
Inhibition of spleen tyrosine kinase as treatment of postoperative ileus.
Gut
; 62(11): 1581-90, 2013 Nov.
Article
in English
| MEDLINE | ID: mdl-23242119
5.
Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening.
J Med Chem
; 63(2): 714-746, 2020 01 23.
Article
in English
| MEDLINE | ID: mdl-31904959
6.
Click chemistry enables preclinical evaluation of targeted epigenetic therapies.
Science
; 356(6345): 1397-1401, 2017 06 30.
Article
in English
| MEDLINE | ID: mdl-28619718
7.
Functional interdependence of BRD4 and DOT1L in MLL leukemia.
Nat Struct Mol Biol
; 23(7): 673-81, 2016 07.
Article
in English
| MEDLINE | ID: mdl-27294782
8.
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Cancer Res
; 75(23): 5106-5119, 2015 Dec 01.
Article
in English
| MEDLINE | ID: mdl-26552700
9.
BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane.
PLoS One
; 8(11): e80746, 2013.
Article
in English
| MEDLINE | ID: mdl-24260471
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