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1.

Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy.

Luoma, Adrienne M; Suo, Shengbao; Wang, Yifan; Gunasti, Lauren; Porter, Caroline B M; Nabilsi, Nancy; Tadros, Jenny; Ferretti, Andrew P; Liao, Sida; Gurer, Cagan; Chen, Yu-Hui; Criscitiello, Shana; Ricker, Cora A; Dionne, Danielle; Rozenblatt-Rosen, Orit; Uppaluri, Ravindra; Haddad, Robert I; Ashenberg, Orr; Regev, Aviv; Van Allen, Eliezer M; MacBeath, Gavin; Schoenfeld, Jonathan D; Wucherpfennig, Kai W.

Cell ; 185(16): 2918-2935.e29, 2022 08 04.

Article in English | MEDLINE | ID: mdl-35803260

2.

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.

Biermann, Jana; Melms, Johannes C; Amin, Amit Dipak; Wang, Yiping; Caprio, Lindsay A; Karz, Alcida; Tagore, Somnath; Barrera, Irving; Ibarra-Arellano, Miguel A; Andreatta, Massimo; Fullerton, Benjamin T; Gretarsson, Kristjan H; Sahu, Varun; Mangipudy, Vaibhav S; Nguyen, Trang T T; Nair, Ajay; Rogava, Meri; Ho, Patricia; Koch, Peter D; Banu, Matei; Humala, Nelson; Mahajan, Aayushi; Walsh, Zachary H; Shah, Shivem B; Vaccaro, Daniel H; Caldwell, Blake; Mu, Michael; Wünnemann, Florian; Chazotte, Margot; Berhe, Simon; Luoma, Adrienne M; Driver, Joseph; Ingham, Matthew; Khan, Shaheer A; Rapisuwon, Suthee; Slingluff, Craig L; Eigentler, Thomas; Röcken, Martin; Carvajal, Richard; Atkins, Michael B; Davies, Michael A; Agustinus, Albert; Bakhoum, Samuel F; Azizi, Elham; Siegelin, Markus; Lu, Chao; Carmona, Santiago J; Hibshoosh, Hanina; Ribas, Antoni; Canoll, Peter.

Cell ; 185(14): 2591-2608.e30, 2022 07 07.

Article in English | MEDLINE | ID: mdl-35803246

3.

Understanding and treating the inflammatory adverse events of cancer immunotherapy.

Dougan, Michael; Luoma, Adrienne M; Dougan, Stephanie K; Wucherpfennig, Kai W.

Cell ; 184(6): 1575-1588, 2021 03 18.

Article in English | MEDLINE | ID: mdl-33675691

4.

The adaptable major histocompatibility complex (MHC) fold: structure and function of nonclassical and MHC class I-like molecules.

Adams, Erin J; Luoma, Adrienne M.

Annu Rev Immunol ; 31: 529-61, 2013.

Article in English | MEDLINE | ID: mdl-23298204

5.

Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy.

Luoma, Adrienne M; Suo, Shengbao; Williams, Hannah L; Sharova, Tatyana; Sullivan, Keri; Manos, Michael; Bowling, Peter; Hodi, F Stephen; Rahma, Osama; Sullivan, Ryan J; Boland, Genevieve M; Nowak, Jonathan A; Dougan, Stephanie K; Dougan, Michael; Yuan, Guo-Cheng; Wucherpfennig, Kai W.

Cell ; 182(3): 655-671.e22, 2020 08 06.

Article in English | MEDLINE | ID: mdl-32603654

6.

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.

Jerby-Arnon, Livnat; Shah, Parin; Cuoco, Michael S; Rodman, Christopher; Su, Mei-Ju; Melms, Johannes C; Leeson, Rachel; Kanodia, Abhay; Mei, Shaolin; Lin, Jia-Ren; Wang, Shu; Rabasha, Bokang; Liu, David; Zhang, Gao; Margolais, Claire; Ashenberg, Orr; Ott, Patrick A; Buchbinder, Elizabeth I; Haq, Rizwan; Hodi, F Stephen; Boland, Genevieve M; Sullivan, Ryan J; Frederick, Dennie T; Miao, Benchun; Moll, Tabea; Flaherty, Keith T; Herlyn, Meenhard; Jenkins, Russell W; Thummalapalli, Rohit; Kowalczyk, Monika S; Cañadas, Israel; Schilling, Bastian; Cartwright, Adam N R; Luoma, Adrienne M; Malu, Shruti; Hwu, Patrick; Bernatchez, Chantale; Forget, Marie-Andrée; Barbie, David A; Shalek, Alex K; Tirosh, Itay; Sorger, Peter K; Wucherpfennig, Kai; Van Allen, Eliezer M; Schadendorf, Dirk; Johnson, Bruce E; Rotem, Asaf; Rozenblatt-Rosen, Orit; Garraway, Levi A; Yoon, Charles H.

Cell ; 175(4): 984-997.e24, 2018 11 01.

Article in English | MEDLINE | ID: mdl-30388455

7.

A molecular single-cell lung atlas of lethal COVID-19.

Melms, Johannes C; Biermann, Jana; Huang, Huachao; Wang, Yiping; Nair, Ajay; Tagore, Somnath; Katsyv, Igor; Rendeiro, André F; Amin, Amit Dipak; Schapiro, Denis; Frangieh, Chris J; Luoma, Adrienne M; Filliol, Aveline; Fang, Yinshan; Ravichandran, Hiranmayi; Clausi, Mariano G; Alba, George A; Rogava, Meri; Chen, Sean W; Ho, Patricia; Montoro, Daniel T; Kornberg, Adam E; Han, Arnold S; Bakhoum, Mathieu F; Anandasabapathy, Niroshana; Suárez-Fariñas, Mayte; Bakhoum, Samuel F; Bram, Yaron; Borczuk, Alain; Guo, Xinzheng V; Lefkowitch, Jay H; Marboe, Charles; Lagana, Stephen M; Del Portillo, Armando; Tsai, Emily J; Zorn, Emmanuel; Markowitz, Glen S; Schwabe, Robert F; Schwartz, Robert E; Elemento, Olivier; Saqi, Anjali; Hibshoosh, Hanina; Que, Jianwen; Izar, Benjamin.

Nature ; 595(7865): 114-119, 2021 07.

Article in English | MEDLINE | ID: mdl-33915568

8.

Targeting of the CD161 inhibitory receptor enhances T-cell-mediated immunity against hematological malignancies.

Alvarez Calderon, Francesca; Kang, Byong H; Kyrysyuk, Oleksandr; Zheng, Shiwei; Wang, Hao; Mathewson, Nathan D; Luoma, Adrienne M; Ning, Xiaohan; Pyrdol, Jason; Cao, Xuan; Suvà, Mario L; Yuan, Guo-Cheng; Wittrup, K Dane; Wucherpfennig, Kai W.

Blood ; 143(12): 1124-1138, 2024 Mar 21.

Article in English | MEDLINE | ID: mdl-38153903

9.

MHC-II neoantigens shape tumour immunity and response to immunotherapy.

Alspach, Elise; Lussier, Danielle M; Miceli, Alexander P; Kizhvatov, Ilya; DuPage, Michel; Luoma, Adrienne M; Meng, Wei; Lichti, Cheryl F; Esaulova, Ekaterina; Vomund, Anthony N; Runci, Daniele; Ward, Jeffrey P; Gubin, Matthew M; Medrano, Ruan F V; Arthur, Cora D; White, J Michael; Sheehan, Kathleen C F; Chen, Alex; Wucherpfennig, Kai W; Jacks, Tyler; Unanue, Emil R; Artyomov, Maxim N; Schreiber, Robert D.

Nature ; 574(7780): 696-701, 2019 10.

Article in English | MEDLINE | ID: mdl-31645760

10.

Molecular design of the Î³Î´T cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing.

Mallis, Robert J; Duke-Cohan, Jonathan S; Das, Dibyendu Kumar; Akitsu, Aoi; Luoma, Adrienne M; Banik, Debasis; Stephens, Hannah M; Tetteh, Paul W; Castro, Caitlin D; Krahnke, Sophie; Hussey, Rebecca E; Lawney, Brian; Brazin, Kristine N; Reche, Pedro A; Hwang, Wonmuk; Adams, Erin J; Lang, Matthew J; Reinherz, Ellis L.

Proc Natl Acad Sci U S A ; 118(26)2021 06 29.

Article in English | MEDLINE | ID: mdl-34172580

11.

Crystal structure of VÎ´1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human Î³Î´ T cells.

Luoma, Adrienne M; Castro, Caitlin D; Mayassi, Toufic; Bembinster, Leslie A; Bai, Li; Picard, Damien; Anderson, Brian; Scharf, Louise; Kung, Jennifer E; Sibener, Leah V; Savage, Paul B; Jabri, Bana; Bendelac, Albert; Adams, Erin J.

Immunity ; 39(6): 1032-42, 2013 Dec 12.

Article in English | MEDLINE | ID: mdl-24239091

12.

Author Correction: A molecular single-cell lung atlas of lethal COVID-19.

Melms, Johannes C; Biermann, Jana; Huang, Huachao; Wang, Yiping; Nair, Ajay; Tagore, Somnath; Katsyv, Igor; Rendeiro, André F; Amin, Amit Dipak; Schapiro, Denis; Frangieh, Chris J; Luoma, Adrienne M; Filliol, Aveline; Fang, Yinshan; Ravichandran, Hiranmayi; Clausi, Mariano G; Alba, George A; Rogava, Meri; Chen, Sean W; Ho, Patricia; Montoro, Daniel T; Kornberg, Adam E; Han, Arnold S; Bakhoum, Mathieu F; Anandasabapathy, Niroshana; Suárez-Fariñas, Mayte; Bakhoum, Samuel F; Bram, Yaron; Borczuk, Alain; Guo, Xinzheng V; Lefkowitch, Jay H; Marboe, Charles; Lagana, Stephen M; Del Portillo, Armando; Tsai, Emily J; Zorn, Emmanuel; Markowitz, Glen S; Schwabe, Robert F; Schwartz, Robert E; Elemento, Olivier; Saqi, Anjali; Hibshoosh, Hanina; Que, Jianwen; Izar, Benjamin.

Nature ; 598(7882): E2, 2021 Oct.

Article in English | MEDLINE | ID: mdl-34625743

13.

The yin and yang of CD1d recognition.

Adams, Erin J; Luoma, Adrienne M.

Nat Immunol ; 13(9): 814-5, 2012 Sep.

Article in English | MEDLINE | ID: mdl-22910387

14.

Coevolution of T-cell receptors with MHC and non-MHC ligands.

Castro, Caitlin D; Luoma, Adrienne M; Adams, Erin J.

Immunol Rev ; 267(1): 30-55, 2015 Sep.

Article in English | MEDLINE | ID: mdl-26284470

15.

Î³Î´ T cell surveillance via CD1 molecules.

Luoma, Adrienne M; Castro, Caitlin D; Adams, Erin J.

Trends Immunol ; 35(12): 613-621, 2014 12.

Article in English | MEDLINE | ID: mdl-25283967

16.

The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins.

López-Sagaseta, Jacinto; Dulberger, Charles L; Crooks, James E; Parks, Chelsea D; Luoma, Adrienne M; McFedries, Amanda; Van Rhijn, Ildiko; Saghatelian, Alan; Adams, Erin J.

Proc Natl Acad Sci U S A ; 110(19): E1771-8, 2013 May 07.

Article in English | MEDLINE | ID: mdl-23613577

17.

Human gamma delta T cells: Evolution and ligand recognition.

Adams, Erin J; Gu, Siyi; Luoma, Adrienne M.

Cell Immunol ; 296(1): 31-40, 2015 Jul.

Article in English | MEDLINE | ID: mdl-25991474

18.

MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets.

Qiu, Xintao; Boufaied, Nadia; Hallal, Tarek; Feit, Avery; de Polo, Anna; Luoma, Adrienne M; Alahmadi, Walaa; Larocque, Janie; Zadra, Giorgia; Xie, Yingtian; Gu, Shengqing; Tang, Qin; Zhang, Yi; Syamala, Sudeepa; Seo, Ji-Heui; Bell, Connor; O'Connor, Edward; Liu, Yang; Schaeffer, Edward M; Jeffrey Karnes, R; Weinmann, Sheila; Davicioni, Elai; Morrissey, Colm; Cejas, Paloma; Ellis, Leigh; Loda, Massimo; Wucherpfennig, Kai W; Pomerantz, Mark M; Spratt, Daniel E; Corey, Eva; Freedman, Matthew L; Shirley Liu, X; Brown, Myles; Long, Henry W; Labbé, David P.

Nat Commun ; 13(1): 2559, 2022 05 13.

Article in English | MEDLINE | ID: mdl-35562350

19.

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion.

Frangieh, Chris J; Melms, Johannes C; Thakore, Pratiksha I; Geiger-Schuller, Kathryn R; Ho, Patricia; Luoma, Adrienne M; Cleary, Brian; Jerby-Arnon, Livnat; Malu, Shruti; Cuoco, Michael S; Zhao, Maryann; Ager, Casey R; Rogava, Meri; Hovey, Lila; Rotem, Asaf; Bernatchez, Chantale; Wucherpfennig, Kai W; Johnson, Bruce E; Rozenblatt-Rosen, Orit; Schadendorf, Dirk; Regev, Aviv; Izar, Benjamin.

Nat Genet ; 53(3): 332-341, 2021 03.

Article in English | MEDLINE | ID: mdl-33649592

20.

cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes.

Roehle, Kevin; Qiang, Li; Ventre, Katherine S; Heid, Daniel; Ali, Lestat R; Lenehan, Patrick; Heckler, Max; Crowley, Stephanie J; Stump, Courtney T; Ro, Gabrielle; Godicelj, Anze; Bhuiyan, Aladdin M; Yang, Annan; Quiles Del Rey, Maria; Biary, Tamara; Luoma, Adrienne M; Bruck, Patrick T; Tegethoff, Jana F; Nopper, Svenja L; Li, Jinyang; Byrne, Katelyn T; Pelletier, Marc; Wucherpfennig, Kai W; Stanger, Ben Z; Akin, James J; Mancias, Joseph D; Agudo, Judith; Dougan, Michael; Dougan, Stephanie K.

Sci Transl Med ; 13(594)2021 05 19.

Article in English | MEDLINE | ID: mdl-34011631

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