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1.

Platelets: Orchestrators of immunity in host defense and beyond.

Nicolai, Leo; Pekayvaz, Kami; Massberg, Steffen.

Immunity ; 57(5): 957-972, 2024 May 14.

Article in English | MEDLINE | ID: mdl-38749398

2.

Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation.

Pekayvaz, Kami; Gold, Christoph; Hoseinpour, Parandis; Engel, Anouk; Martinez-Navarro, Alejandro; Eivers, Luke; Coletti, Raffaele; Joppich, Markus; Dionísio, Flávio; Kaiser, Rainer; Tomas, Lukas; Janjic, Aleksandar; Knott, Maximilian; Mehari, Fitsumbirhan; Polewka, Vivien; Kirschner, Megan; Boda, Annegret; Nicolai, Leo; Schulz, Heiko; Titova, Anna; Kilani, Badr; Lorenz, Michael; Fingerle-Rowson, Günter; Bucala, Richard; Enard, Wolfgang; Zimmer, Ralf; Weber, Christian; Libby, Peter; Schulz, Christian; Massberg, Steffen; Stark, Konstantin.

Immunity ; 56(10): 2325-2341.e15, 2023 Oct 10.

Article in English | MEDLINE | ID: mdl-37652021

3.

Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.

Gaertner, Florian; Ahmad, Zerkah; Rosenberger, Gerhild; Fan, Shuxia; Nicolai, Leo; Busch, Benjamin; Yavuz, Gökce; Luckner, Manja; Ishikawa-Ankerhold, Hellen; Hennel, Roman; Benechet, Alexandre; Lorenz, Michael; Chandraratne, Sue; Schubert, Irene; Helmer, Sebastian; Striednig, Bianca; Stark, Konstantin; Janko, Marek; Böttcher, Ralph T; Verschoor, Admar; Leon, Catherine; Gachet, Christian; Gudermann, Thomas; Mederos Y Schnitzler, Michael; Pincus, Zachary; Iannacone, Matteo; Haas, Rainer; Wanner, Gerhard; Lauber, Kirsten; Sixt, Michael; Massberg, Steffen.

Cell ; 171(6): 1368-1382.e23, 2017 Nov 30.

Article in English | MEDLINE | ID: mdl-29195076

4.

Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.

Petzold, Tobias; Zhang, Zhe; Ballesteros, Iván; Saleh, Inas; Polzin, Amin; Thienel, Manuela; Liu, Lulu; Ul Ain, Qurrat; Ehreiser, Vincent; Weber, Christian; Kilani, Badr; Mertsch, Pontus; Götschke, Jeremias; Cremer, Sophie; Fu, Wenwen; Lorenz, Michael; Ishikawa-Ankerhold, Hellen; Raatz, Elisabeth; El-Nemr, Shaza; Görlach, Agnes; Marhuenda, Esther; Stark, Konstantin; Pircher, Joachim; Stegner, David; Gieger, Christian; Schmidt-Supprian, Marc; Gaertner, Florian; Almendros, Isaac; Kelm, Malte; Schulz, Christian; Hidalgo, Andrés; Massberg, Steffen.

Immunity ; 55(12): 2285-2299.e7, 2022 12 13.

Article in English | MEDLINE | ID: mdl-36272416

5.

Inflammaging aggravates stroke pathology.

Schulz, Christian; Massberg, Steffen.

Nat Immunol ; 24(6): 887-888, 2023 06.

Article in English | MEDLINE | ID: mdl-37188943

6.

Thrombin: A Gas Pedal Driving Innate Immunity.

Petzold, Tobias; Massberg, Steffen.

Immunity ; 50(4): 1024-1026, 2019 04 16.

Article in English | MEDLINE | ID: mdl-30995493

7.

Transcatheter or Surgical Treatment of Aortic-Valve Stenosis.

Blankenberg, Stefan; Seiffert, Moritz; Vonthein, Reinhard; Baumgartner, Helmut; Bleiziffer, Sabine; Borger, Michael A; Choi, Yeong-Hoon; Clemmensen, Peter; Cremer, Jochen; Czerny, Martin; Diercks, Nina; Eitel, Ingo; Ensminger, Stephan; Frank, Derk; Frey, Norbert; Hagendorff, Andreas; Hagl, Christian; Hamm, Christian; Kappert, Utz; Karck, Matthias; Kim, Won-Keun; König, Inke R; Krane, Markus; Landmesser, Ulf; Linke, Axel; Maier, Lars S; Massberg, Steffen; Neumann, Franz-Josef; Reichenspurner, Hermann; Rudolph, Tanja K; Schmid, Christof; Thiele, Holger; Twerenbold, Raphael; Walther, Thomas; Westermann, Dirk; Xhepa, Erion; Ziegler, Andreas; Falk, Volkmar.

N Engl J Med ; 390(17): 1572-1583, 2024 May 02.

Article in English | MEDLINE | ID: mdl-38588025

8.

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.

Fidler, Trevor P; Xue, Chenyi; Yalcinkaya, Mustafa; Hardaway, Brian; Abramowicz, Sandra; Xiao, Tong; Liu, Wenli; Thomas, David G; Hajebrahimi, Mohammad Ali; Pircher, Joachim; Silvestre-Roig, Carlos; Kotini, Andriana G; Luchsinger, Larry L; Wei, Ying; Westerterp, Marit; Snoeck, Hans-Willem; Papapetrou, Eirini P; Schulz, Christian; Massberg, Steffen; Soehnlein, Oliver; Ebert, Benjamin; Levine, Ross L; Reilly, Muredach P; Libby, Peter; Wang, Nan; Tall, Alan R.

Nature ; 592(7853): 296-301, 2021 04.

Article in English | MEDLINE | ID: mdl-33731931

9.

Jak2 V617F clonal hematopoiesis promotes arterial thrombosis via platelet activation and cross talk.

Liu, Wenli; Pircher, Joachim; Schuermans, Art; Ul Ain, Qurrat; Zhang, Zhe; Honigberg, Michael C; Yalcinkaya, Mustafa; Nakao, Tetsushi; Pournamadri, Ashley; Xiao, Tong; Hajebrahimi, Mohammad Ali; Wasner, Lisa; Stegner, David; Petzold, Tobias; Natarajan, Pradeep; Massberg, Steffen; Tall, Alan R; Schulz, Christian; Wang, Nan.

Blood ; 143(15): 1539-1550, 2024 Apr 11.

Article in English | MEDLINE | ID: mdl-38142422

10.

Scrutinizing the Role of Venoarterial Extracorporeal Membrane Oxygenation: Has Clinical Practice Outpaced the Evidence?

Lüsebrink, Enzo; Binzenhöfer, Leonhard; Hering, Daniel; Villegas Sierra, Laura; Schrage, Benedikt; Scherer, Clemens; Speidl, Walter S; Uribarri, Aitor; Sabate, Manel; Noc, Marko; Sandoval, Elena; Erglis, Andrejs; Pappalardo, Federico; De Roeck, Frederic; Tavazzi, Guido; Riera, Jordi; Roncon-Albuquerque, Roberto; Meder, Benjamin; Luedike, Peter; Rassaf, Tienush; Hausleiter, Jörg; Hagl, Christian; Zimmer, Sebastian; Westermann, Dirk; Combes, Alain; Zeymer, Uwe; Massberg, Steffen; Schäfer, Andreas; Orban, Martin; Thiele, Holger.

Circulation ; 149(13): 1033-1052, 2024 03 26.

Article in English | MEDLINE | ID: mdl-38527130

11.

Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement.

Kapadia, Samir R; Makkar, Raj; Leon, Martin; Abdel-Wahab, Mohamed; Waggoner, Thomas; Massberg, Steffen; Rottbauer, Wolfgang; Horr, Samuel; Sondergaard, Lars; Karha, Juhana; Gooley, Robert; Satler, Lowell; Stoler, Robert C; Messé, Steven R; Baron, Suzanne J; Seeger, Julia; Kodali, Susheel; Krishnaswamy, Amar; Thourani, Vinod H; Harrington, Katherine; Pocock, Stuart; Modolo, Rodrigo; Allocco, Dominic J; Meredith, Ian T; Linke, Axel.

N Engl J Med ; 387(14): 1253-1263, 2022 10 06.

Article in English | MEDLINE | ID: mdl-36121045

12.

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs.

Stark, Konstantin; Eckart, Annekathrin; Haidari, Selgai; Tirniceriu, Anca; Lorenz, Michael; von Brühl, Marie-Luise; Gärtner, Florian; Khandoga, Alexander Georg; Legate, Kyle R; Pless, Robert; Hepper, Ingrid; Lauber, Kirsten; Walzog, Barbara; Massberg, Steffen.

Nat Immunol ; 14(1): 41-51, 2013 Jan.

Article in English | MEDLINE | ID: mdl-23179077

13.

Mechanosensing via a GpIIb/Src/14-3-3Î¶ axis critically regulates platelet migration in vascular inflammation.

Kaiser, Rainer; Anjum, Afra; Kammerer, Lisa; Loew, Quentin; Akhalkatsi, Anastassia; Rossaro, Dario; Escaig, Raphael; Droste Zu Senden, Augustin; Raude, Ben; Lorenz, Michael; Gold, Christoph; Pekayvaz, Kami; Brocker, Thomas; Kranich, Jan; Holch, Julian Walter; Spiekermann, Karsten; Massberg, Steffen; Gaertner, Florian; Nicolai, Leo.

Blood ; 141(24): 2973-2992, 2023 06 15.

Article in English | MEDLINE | ID: mdl-37018659

14.

Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials.

Zeymer, Uwe; Freund, Anne; Hochadel, Matthias; Ostadal, Petr; Belohlavek, Jan; Rokyta, Richard; Massberg, Steffen; Brunner, Stefan; Lüsebrink, Enzo; Flather, Marcus; Adlam, David; Bogaerts, Kris; Banning, Amerjeet; Sabaté, Manel; Akin, Ibrahim; Jobs, Alexander; Schneider, Steffen; Desch, Steffen; Thiele, Holger.

Lancet ; 402(10410): 1338-1346, 2023 10 14.

Article in English | MEDLINE | ID: mdl-37643628

15.

Atrial Fibrillation Risk Assessment after Embolic Stroke of Undetermined Source.

von Falkenhausen, Aenne S; Feil, Katharina; Sinner, Moritz F; Schönecker, Sonja; Müller, Johanna; Wischmann, Johannes; Eiffener, Elodie; Clauss, Sebastian; Poli, Sven; Poli, Khouloud; Zuern, Christine S; Ziemann, Ulf; Berrouschot, Jörg; Kitsiou, Alkisti; Schäbitz, Wolf-Rüdiger; Dieterich, Marianne; Massberg, Steffen; Kääb, Stefan; Kellert, Lars.

Ann Neurol ; 93(3): 479-488, 2023 03.

Article in English | MEDLINE | ID: mdl-36373166

16.

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI.

Kaiser, Rainer; Escaig, Raphael; Kranich, Jan; Hoffknecht, Marie-Louise; Anjum, Afra; Polewka, Vivien; Mader, Magdalena; Hu, Wenbo; Belz, Larissa; Gold, Christoph; Titova, Anna; Lorenz, Michael; Pekayvaz, Kami; Kääb, Stefan; Gaertner, Florian; Stark, Konstantin; Brocker, Thomas; Massberg, Steffen; Nicolai, Leo.

Blood ; 140(2): 121-139, 2022 07 14.

Article in English | MEDLINE | ID: mdl-35472164

17.

Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration.

Nicolai, Leo; Leunig, Alexander; Pekayvaz, Kami; Esefeld, Max; Anjum, Afra; Rath, Justina; Riedlinger, Eva; Ehreiser, Vincent; Mader, Magdalena; Eivers, Luke; Hoffknecht, Marie-Louise; Zhang, Zhe; Kugelmann, Daniela; Rossaro, Dario; Escaig, Raphael; Kaiser, Rainer; Polewka, Vivien; Titova, Anna; Petzold, Tobias; Spiekermann, Karsten; Iannacone, Matteo; Thiele, Thomas; Greinacher, Andreas; Stark, Konstantin; Massberg, Steffen.

Blood ; 140(5): 478-490, 2022 08 04.

Article in English | MEDLINE | ID: mdl-35486845

18.

Mutual regulation of CD4+ T cells and intravascular fibrin in infections.

Mueller, Tonina T; Pilartz, Mona; Thakur, Manovriti; LangHeinrich, Torben; Luo, Junfu; Block, Rebecca; Hoeflinger, Jonathan K L; Meister, Sarah; Karaj, Flavio; Perez, Laura Garcia; Öllinger, Rupert; Engleitner, Thomas; Thoss, Jakob; Voelkl, Michael; Tersteeg, Claudia; Koedel, Uwe; Kohlmaier, Alexander Zigman; Teupser, Daniel; Wygrecka, Malgorzata; Ye, Haifeng; Preissner, Klaus T; Radbruch, Helena; Elezkurtaj, Sefer; Mack, Matthias; Von Hundelshausen, Philipp; Weber, Christian; Massberg, Steffen; Schulz, Christian; Rad, Roland; Huber, Samuel; Ishikawa-Ankerhold, Hellen; Engelmann, Bernd.

Haematologica ; 2024 Apr 04.

Article in English | MEDLINE | ID: mdl-38572559

19.

Concomitant percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation.

Fischer, Julius; Steffen, Julius; Arlart, Tobias; Haum, Magda; Gschwendtner, Sarah; Doldi, Philipp M; Rizas, Konstantinos; Theiss, Hans; Braun, Daniel; Orban, Martin; Peterß, Sven; Hausleiter, Jörg; Massberg, Steffen; Deseive, Simon.

Catheter Cardiovasc Interv ; 103(1): 186-193, 2024 01.

Article in English | MEDLINE | ID: mdl-38140761

20.

Dual antiplatelet therapy de-escalation in acute coronary syndrome: an individual patient meta-analysis.

Kang, Jeehoon; Rizas, Konstantinos D; Park, Kyung Woo; Chung, Jaewook; van den Broek, Wout; Claassens, Daniel M F; Choo, Eun Ho; Aradi, Dániel; Massberg, Steffen; Hwang, Doyeon; Han, Jung-Kyu; Yang, Han-Mo; Kang, Hyun-Jae; Chang, Kiyuk; Ten Berg, Jur M; Sibbing, Dirk; Koo, Bon-Kwon; Kim, Hyo-Soo.

Eur Heart J ; 44(15): 1360-1370, 2023 04 17.

Article in English | MEDLINE | ID: mdl-36883613

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