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1.

Increased PHGDH expression promotes aberrant melanin accumulation.

Mattaini, Katherine R; Sullivan, Mark R; Lau, Allison N; Fiske, Brian P; Bronson, Roderick T; Vander Heiden, Matthew G.

BMC Cancer ; 19(1): 723, 2019 Jul 22.

Article in English | MEDLINE | ID: mdl-31331318

2.

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.

Metallo, Christian M; Gameiro, Paulo A; Bell, Eric L; Mattaini, Katherine R; Yang, Juanjuan; Hiller, Karsten; Jewell, Christopher M; Johnson, Zachary R; Irvine, Darrell J; Guarente, Leonard; Kelleher, Joanne K; Vander Heiden, Matthew G; Iliopoulos, Othon; Stephanopoulos, Gregory.

Nature ; 481(7381): 380-4, 2011 Nov 20.

Article in English | MEDLINE | ID: mdl-22101433

3.

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

Anastasiou, Dimitrios; Yu, Yimin; Israelsen, William J; Jiang, Jian-Kang; Boxer, Matthew B; Hong, Bum Soo; Tempel, Wolfram; Dimov, Svetoslav; Shen, Min; Jha, Abhishek; Yang, Hua; Mattaini, Katherine R; Metallo, Christian M; Fiske, Brian P; Courtney, Kevin D; Malstrom, Scott; Khan, Tahsin M; Kung, Charles; Skoumbourdis, Amanda P; Veith, Henrike; Southall, Noel; Walsh, Martin J; Brimacombe, Kyle R; Leister, William; Lunt, Sophia Y; Johnson, Zachary R; Yen, Katharine E; Kunii, Kaiko; Davidson, Shawn M; Christofk, Heather R; Austin, Christopher P; Inglese, James; Harris, Marian H; Asara, John M; Stephanopoulos, Gregory; Salituro, Francesco G; Jin, Shengfang; Dang, Lenny; Auld, Douglas S; Park, Hee-Won; Cantley, Lewis C; Thomas, Craig J; Vander Heiden, Matthew G.

Nat Chem Biol ; 8(10): 839-47, 2012 Oct.

Article in English | MEDLINE | ID: mdl-22922757

4.

The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor.

Crawford, Nigel P S; Yang, Hailiu; Mattaini, Katherine R; Hunter, Kent W.

J Biol Chem ; 284(42): 28660-73, 2009 Oct 16.

Article in English | MEDLINE | ID: mdl-19710015

5.

Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting.

Sullivan, Mark R; Mattaini, Katherine R; Dennstedt, Emily A; Nguyen, Anna A; Sivanand, Sharanya; Reilly, Montana F; Meeth, Katrina; Muir, Alexander; Darnell, Alicia M; Bosenberg, Marcus W; Lewis, Caroline A; Vander Heiden, Matthew G.

Cell Metab ; 29(6): 1410-1421.e4, 2019 06 04.

Article in English | MEDLINE | ID: mdl-30905671

6.

The importance of serine metabolism in cancer.

Mattaini, Katherine R; Sullivan, Mark R; Vander Heiden, Matthew G.

J Cell Biol ; 214(3): 249-57, 2016 08 01.

Article in English | MEDLINE | ID: mdl-27458133

7.

Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate.

Fan, Jing; Teng, Xin; Liu, Ling; Mattaini, Katherine R; Looper, Ryan E; Vander Heiden, Matthew G; Rabinowitz, Joshua D.

ACS Chem Biol ; 10(2): 510-6, 2015 Feb 20.

Article in English | MEDLINE | ID: mdl-25406093

8.

An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.

Mattaini, Katherine R; Brignole, Edward J; Kini, Mitali; Davidson, Shawn M; Fiske, Brian P; Drennan, Catherine L; Vander Heiden, Matthew G.

Cancer Metab ; 3: 5, 2015.

Article in English | MEDLINE | ID: mdl-25926973

9.

BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane.

Alsarraj, Jude; Faraji, Farhoud; Geiger, Thomas R; Mattaini, Katherine R; Williams, Mia; Wu, Josephine; Ha, Ngoc-Han; Merlino, Tyler; Walker, Renard C; Bosley, Allen D; Xiao, Zhen; Andresson, Thorkell; Esposito, Dominic; Smithers, Nicholas; Lugo, Dave; Prinjha, Rab; Day, Anup; Crawford, Nigel P S; Ozato, Keiko; Gardner, Kevin; Hunter, Kent W.

PLoS One ; 8(11): e80746, 2013.

Article in English | MEDLINE | ID: mdl-24260471

10.

PHGDH amplification and altered glucose metabolism in human melanoma.

Mullarky, Edouard; Mattaini, Katherine R; Vander Heiden, Matthew G; Cantley, Lewis C; Locasale, Jason W.

Pigment Cell Melanoma Res ; 24(6): 1112-5, 2011 Dec.

Article in English | MEDLINE | ID: mdl-21981974

11.

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.

Locasale, Jason W; Grassian, Alexandra R; Melman, Tamar; Lyssiotis, Costas A; Mattaini, Katherine R; Bass, Adam J; Heffron, Gregory; Metallo, Christian M; Muranen, Taru; Sharfi, Hadar; Sasaki, Atsuo T; Anastasiou, Dimitrios; Mullarky, Edouard; Vokes, Natalie I; Sasaki, Mika; Beroukhim, Rameen; Stephanopoulos, Gregory; Ligon, Azra H; Meyerson, Matthew; Richardson, Andrea L; Chin, Lynda; Wagner, Gerhard; Asara, John M; Brugge, Joan S; Cantley, Lewis C; Vander Heiden, Matthew G.

Nat Genet ; 43(9): 869-74, 2011 Jul 31.

Article in English | MEDLINE | ID: mdl-21804546

12.

Cancer. Glycosylation to adapt to stress.

Mattaini, Katherine R; Vander Heiden, Matthew G.

Science ; 337(6097): 925-6, 2012 Aug 24.

Article in English | MEDLINE | ID: mdl-22923571

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