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1.
Eur Arch Otorhinolaryngol ; 273(10): 2917-23, 2016 Oct.
Article in English | MEDLINE | ID: mdl-26525884

ABSTRACT

Chronic rhinosinusitis is a common debilitating condition characterized by inflammation of the nose and paranasal sinuses. Osteitis is an associated finding but it is not clear whether it is cause or effect. This review will report on studies that have examined the role of osteitis in CRS, with the ultimate aim of clarifying the definition, pathogenesis and clinical implications of this relatively new clinical entity. Literature searches of Medline, EMBASE and CENTRAL using the search terms osteitis, rhinosinusitis, sinusitis, rhinitis, chronic disease, and recurrence were performed. 21 articles were identified and reviewed. The papers highlighted key pathological features including periosteal thickening, new woven bone formation, bone resorption, fibrosis and inflammatory cell infiltration. Radiological grading systems and basic science research into the role of matrix metalloproteinases and P-glycoprotein were also identified and reviewed.


Subject(s)
Osteitis/complications , Rhinitis/etiology , Sinusitis/etiology , ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism , Bone Remodeling , Chronic Disease , Humans , Matrix Metalloproteinases/metabolism , Osteitis/diagnostic imaging , Osteitis/metabolism , Osteitis/pathology , Radiography , Recurrence
2.
Soc Sci Med ; 46(6): 719-27, 1998 Mar.
Article in English | MEDLINE | ID: mdl-9522431

ABSTRACT

This paper considers the public health risks of Lyme disease, a borrelial infection transmitted to humans chiefly by nymphal Ixodes ticks. A study undertaken in the Breckland area of East Anglia, U.K., combined analysis of the spatial and temporal factors affecting tick activity at recreational sites with a survey of current levels of disease awareness among visitors to these locations. Significant relationships were found between densities of questing ticks and vegetation type, relative humidity and temperature. More than two thirds of the general public visiting the sites were aware ticks could carry diseases, but only 13% recognized an unfed nymph, and under half knew that Lyme disease could be contracted from tick bites. Such results need to be taken into account when formulating public health and education measures.


Subject(s)
Lyme Disease , Borrelia burgdorferi Group/growth & development , Colony Count, Microbial , Health Education , Humans , Lyme Disease/epidemiology , Public Health , United Kingdom/epidemiology
3.
Cochlear Implants Int ; 15(2): 109-11, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24156503

ABSTRACT

OBJECTIVES: This study aims to assess the safety of daycase cochlear implant surgery. METHODS: A retrospective review was conducted on all patients who underwent cochlear implant surgery at a teaching hospital in Oxford, UK between September 2008 and February 2012. RESULTS: One hundred and sixteen patients underwent cochlear implant surgery. This included 73 adults and 43 children. Twenty-six patients underwent the procedure as a daycase procedure. There were no readmissions. DISCUSSION: The demand 'to do more with less' has led to increasing drives for efficiency and cost-effectiveness. Therefore, the role of daycase surgery is becoming increasingly widespread. Daycase surgery has been shown to be advantageous for both patients and hospitals. CONCLUSION: Daycase cochlear implant surgery is feasible and can be safely conducted in a select group of patients.


Subject(s)
Ambulatory Surgical Procedures/statistics & numerical data , Cochlear Implantation/statistics & numerical data , Cochlear Implants/statistics & numerical data , Deafness/surgery , Adult , Ambulatory Surgical Procedures/economics , Child , Cochlear Implantation/economics , Cochlear Implants/economics , Cost Savings , Feasibility Studies , Humans , Infant , Length of Stay/economics , Medical Audit , Patient Selection , Retrospective Studies , Treatment Outcome , United Kingdom
4.
J Laryngol Otol ; 127(8): 825-7, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23809610

ABSTRACT

OBJECTIVE: To report a case of varix of the retromandibular vein within the parotid gland. METHODS: Case report, and discussion of the appropriate selection and use of radiological investigation techniques. RESULTS: A 64-year-old lady who presented with unilateral tinnitus underwent a magnetic resonance imaging scan to exclude a vestibular schwannoma. The magnetic resonance scout images revealed an incidental finding of a hyperechoic mass within the parotid gland. The mass was most consistent with a pleomorphic adenoma. Ultrasound-guided fine needle aspiration cytology was arranged; the ultrasound identified the mass as a varix of the retromandibular vein and fine needle aspiration cytology was not performed. CONCLUSION: A varix of the retromandibular vein is a very rare cause of a parotid mass. Appropriate radiological investigations can prevent unnecessary invasive investigations or procedures.


Subject(s)
Adenoma, Pleomorphic/diagnosis , Parotid Gland/blood supply , Parotid Neoplasms/diagnosis , Varicose Veins/diagnosis , Adenoma, Pleomorphic/pathology , Biopsy, Fine-Needle , Diagnosis, Differential , Female , Humans , Incidental Findings , Magnetic Resonance Imaging , Middle Aged , Parotid Gland/pathology , Parotid Neoplasms/pathology , Rare Diseases , Tinnitus/etiology , Varicose Veins/pathology
5.
J Laryngol Otol ; 126(10): 1049-55, 2012 Oct.
Article in English | MEDLINE | ID: mdl-22892105

ABSTRACT

OBJECTIVE: The World Health Organization 'Surgical Safety Checklist' has been adopted by UK surgical units following National Patient Safety Agency guidance. Our aim was to assess compliance with our local version of this Checklist. METHODS: Otolaryngology trainee doctors prospectively assessed compliance with the local Checklist over a six-week period. A staff educational intervention was implemented and the audit was repeated 12 months later. RESULTS: A total of 72 cases were assessed. The initial audit found that: 44 per cent of procedures were undocumented at 'Sign in'; 'Time out' was inappropriately interrupted in 39 per cent of cases; the procedure started before Checklist completion in 33 per cent of cases; and the 'Sign out' was not read out in 94 per cent of cases and was not fully documented in 42 per cent of cases. Following education, re-audit indicated that overall compliance had improved from 63.7 per cent (± 8.9 per cent standard error of the mean) to 90.4 per cent (± 2.7 per cent standard error of the mean). CONCLUSION: Our completed audit cycle demonstrated a significant improvement in Checklist compliance following educational intervention. We discuss barriers to compliance, as well as strategies for quality improvement, and we call for other surgeons to similarly publish their Checklist experience and assess its impact on surgical outcomes.


Subject(s)
Checklist , Guideline Adherence , Patient Safety , Surgical Procedures, Operative/standards , World Health Organization , Adult , Humans , United Kingdom
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