Search | VHL Search Portal

1.

Context-specific regulation and function of mRNA alternative polyadenylation.

Mitschka, Sibylle; Mayr, Christine.

Nat Rev Mol Cell Biol ; 23(12): 779-796, 2022 12.

Article in English | MEDLINE | ID: mdl-35798852

2.

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3'UTR-Mediated Protein-Protein Interactions.

Ma, Weirui; Mayr, Christine.

Cell ; 175(6): 1492-1506.e19, 2018 11 29.

Article in English | MEDLINE | ID: mdl-30449617

3.

Subcytoplasmic location of translation controls protein output.

Horste, Ellen L; Fansler, Mervin M; Cai, Ting; Chen, Xiuzhen; Mitschka, Sibylle; Zhen, Gang; Lee, Flora C Y; Ule, Jernej; Mayr, Christine.

Mol Cell ; 83(24): 4509-4523.e11, 2023 Dec 21.

Article in English | MEDLINE | ID: mdl-38134885

4.

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

Lee, Shih-Han; Mayr, Christine.

Mol Cell ; 74(4): 701-712.e9, 2019 05 16.

Article in English | MEDLINE | ID: mdl-30948266

5.

Regulation by 3'-Untranslated Regions.

Mayr, Christine.

Annu Rev Genet ; 51: 171-194, 2017 11 27.

Article in English | MEDLINE | ID: mdl-28853924

6.

A working model for condensate RNA-binding proteins as matchmakers for protein complex assembly.

Chen, Xiuzhen; Mayr, Christine.

RNA ; 28(1): 76-87, 2022 01.

Article in English | MEDLINE | ID: mdl-34706978

7.

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells.

Mayr, Christine; Bartel, David P.

Cell ; 138(4): 673-84, 2009 Aug 21.

Article in English | MEDLINE | ID: mdl-19703394

8.

Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia.

Lee, Shih-Han; Singh, Irtisha; Tisdale, Sarah; Abdel-Wahab, Omar; Leslie, Christina S; Mayr, Christine.

Nature ; 561(7721): 127-131, 2018 09.

Article in English | MEDLINE | ID: mdl-30150773

9.

Alternative 3' UTRs act as scaffolds to regulate membrane protein localization.

Berkovits, Binyamin D; Mayr, Christine.

Nature ; 522(7556): 363-7, 2015 Jun 18.

Article in English | MEDLINE | ID: mdl-25896326

10.

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression.

Lianoglou, Steve; Garg, Vidur; Yang, Julie L; Leslie, Christina S; Mayr, Christine.

Genes Dev ; 27(21): 2380-96, 2013 Nov 01.

Article in English | MEDLINE | ID: mdl-24145798

11.

Protein complexes assemble as they are being made.

Mayr, Christine.

Nature ; 561(7722): 186-187, 2018 09.

Article in English | MEDLINE | ID: mdl-30194367

12.

Systems-based approaches enable identification of gene targets which improve the flavour profile of low-ethanol wine yeast strains.

Varela, Cristian; Schmidt, Simon A; Borneman, Anthony R; Pang, Chi Nam Ignatius; Krömerx, Jens O; Khan, Alamgir; Song, Xiaomin; Hodson, Mark P; Solomon, Mark; Mayr, Christine M; Hines, Wade; Pretorius, Isak S; Baker, Mark S; Roessner, Ute; Mercurio, Meagan; Henschke, Paul A; Wilkins, Marc R; Chambers, Paul J.

Metab Eng ; 49: 178-191, 2018 09.

Article in English | MEDLINE | ID: mdl-30138679

13.

High-resolution mass spectrometry metabolomics of grape chemical markers to reveal use of not-allowed varieties in the production of Amarone and Recioto wines.

De Rosso, Mirko; Mayr, Christine M; Girardi, Giordano; Vedova, Antonio Dalla; Flamini, Riccardo.

Metabolomics ; 14(10): 124, 2018 09 17.

Article in English | MEDLINE | ID: mdl-30830408

14.

Alternative isoform regulation in human tissue transcriptomes.

Wang, Eric T; Sandberg, Rickard; Luo, Shujun; Khrebtukova, Irina; Zhang, Lu; Mayr, Christine; Kingsmore, Stephen F; Schroth, Gary P; Burge, Christopher B.

Nature ; 456(7221): 470-6, 2008 Nov 27.

Article in English | MEDLINE | ID: mdl-18978772

15.

Quantifying 3'UTR length from scRNA-seq data reveals changes independent of gene expression.

Fansler, Mervin M; Mitschka, Sibylle; Mayr, Christine.

Nat Commun ; 15(1): 4050, 2024 May 14.

Article in English | MEDLINE | ID: mdl-38744866

16.

The FXR1 network acts as signaling scaffold for actomyosin remodeling.

Chen, Xiuzhen; Fansler, Mervin M; Janjos, Urska; Ule, Jernej; Mayr, Christine.

bioRxiv ; 2023 Nov 05.

Article in English | MEDLINE | ID: mdl-37961296

17.

mRNA interactions with disordered regions control protein activity.

Luo, Yang; Pratihar, Supriya; Horste, Ellen H; Mitschka, Sibylle; Mey, Antonia S J S; Al-Hashimi, Hashim M; Mayr, Christine.

bioRxiv ; 2023 Feb 18.

Article in English | MEDLINE | ID: mdl-36824771

18.

Enhancers regulate 3' end processing activity to control expression of alternative 3'UTR isoforms.

Kwon, Buki; Fansler, Mervin M; Patel, Neil D; Lee, Jihye; Ma, Weirui; Mayr, Christine.

Nat Commun ; 13(1): 2709, 2022 05 17.

Article in English | MEDLINE | ID: mdl-35581194

19.

miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.

Pallasch, Christian Philipp; Patz, Michaela; Park, Yoon Jung; Hagist, Susanne; Eggle, Daniela; Claus, Rainer; Debey-Pascher, Svenja; Schulz, Alexandra; Frenzel, Lukas P; Claasen, Julia; Kutsch, Nadine; Krause, Günter; Mayr, Christine; Rosenwald, Andreas; Plass, Christoph; Schultze, Joachim L; Hallek, Michael; Wendtner, Clemens-Martin.

Blood ; 114(15): 3255-64, 2009 Oct 08.

Article in English | MEDLINE | ID: mdl-19692702

20.

Endogenous p53 expression in human and mouse is not regulated by its 3'UTR.