The Feasibility, Acceptability, and Utility of Mantente REAL: the Culturally Adapted Version of keepin' it REAL for Mexico.

A binational team of investigators culturally adapted, implemented, and tested the efficacy in Mexico of keepin' it REAL, a US-designed prevention intervention for youth. This article reports on the social validity of the adapted intervention by assessing its feasibility, acceptability, and utility, as perceived by participating middle school students, teachers/implementers, and school administrators. Middle schools (N = 36) were randomly assigned to (1) the culturally adapted version for Mexico (Mantente REAL), (2) the original intervention from the USA (keepin' it REAL) translated into Spanish, or (3) a control condition (treatment as usual). Adult and child feedback about the adapted and original versions of the intervention indicate that both are feasible to implement in the Mexican context. Implementation fidelity was equally high for both versions of the manualized intervention. Students, however, were more satisfied with the culturally adapted version than with the non-adapted version. They reported gaining more knowledge, finding it more acceptable, applicable, and authentic, and they reported discussing the program with their family and friends more often. The findings support the feasibility of engaging classroom teachers to implement manualized prevention programs in Mexico. These findings also advance prevention science by documenting the importance of cultural adaptation as a means to increase students' identification with and acceptability of efficacious school-based interventions. The article discusses the practice, policy, and future prevention research implications of the findings for Mexico and their potential generalizability to other middle- and lower-income countries.

Disorders of Sex Development and Malignant Germ Cell Tumors.

A woman, aged 44 years, presented at the general oncology outpatient clinic with bloating, abdominal pain, and significant unintended weight loss. Her past medical history included a bilateral inguinal hernia surgical repair at age 6, and primary amenorrhea since age 15. The patient never underwent additional studies to identify the cause of the primary amenorrhea.

Binational Cultural Adaptation of the keepin' it REAL Substance Use Prevention Program for Adolescents in Mexico.

Sharp increases in substance use rates among youth and the lack of evidence-based prevention interventions in Mexico are a major concern. A team of investigators from Mexico and the USA are actively addressing this gap by culturally adapting keepin' it REAL (kiR)-a former US SAMHSA model program-for Mexico. This paper reports on the processes and outcomes of the cultural adaptation of kiR for adolescents in Mexico. Multiple forms of data informed this cultural adaptation, including focus groups with students about gendered and violence experiences with substance use, feedback from teachers who previously implemented the original versions of kiR, lesson fidelity observations, and external expert reviews. The culturally adapted version of kiR integrates Ecological Validity and Cultural Sensitivity Models in the adaptation process. The process encompassed surface structure adaptations, like updating language, graphics, and videos, as well as deep structure adaptation components including cultural norms, attitudes, and beliefs salient among Mexican adolescents. Youth reported receiving alcohol offers from family members, links between substance use and violence, and that shifting gender norms result in more females initiating substance use offers. In adapted kiR activities, students practice navigating substance use offers in these contexts. This approach to cultural adaptation led to a true collaborative between investigators in two countries. This study advances knowledge about how to undertake cultural adaptations of efficacious US-based prevention programs in international settings.

Reciprocal Effects of Alcohol Use and Violence Perpetration Among Early Adolescents in Mexico: A Gendered Analysis.

Although substance use and violent behaviors often emerge together in adolescence, and both have similar widely cited causes and negative consequences for development, it remains unclear whether and how they may be linked causally. This study of early adolescents in Mexico's three largest cities tested whether alcohol use and violence perpetration are temporally related, whether their relationship is unidirectional or reciprocal, and whether the relationship differs by gender and the type of violence. The study employed longitudinal data from seventh grade students (N = 4830; M age = 12.0, range 11-15; 49% female) in 18 public middle schools in Mexico City, Guadalajara and Monterrey. Students completed questionnaires at the beginning, middle, and end of the 2014-2015 academic year. Students' responses to a multi-dimensional violence assessment emerged in two distinct patterns: criminally violent acts, and bullying/aggression. Although males engaged in both types of violence more frequently than females at all three time points, they used alcohol more frequently than females only at the first survey, after which the gender gap disappeared. Cross-lagged multi-group path models showed that, for both males and females, more frequent alcohol use predicted subsequent increases in criminally violent behavior, and bullying/aggression predicted later increases in alcohol use. Reciprocal associations varied by gender and type of violence: Alcohol use was reciprocally linked to criminally violent behavior among males only, and reciprocally linked to bullying-aggression among females alone. The results are interpreted in the context of sharply increasing rates of violence in Mexico and changing gender norms, with implications for youth prevention programs.

History of child sexual abuse among women consuming illicit substances in Mexico City.

INTRODUCTION: Child sexual abuse (CSA) is a pervasive problem that has been linked to numerous developmental, social, health, and substance use consequences. Nevertheless, the relationship between CSA and the consumption of psychoactive substances has not been adequately studied in Mexico. The present study aims to examine this association between history of CSA and illicit substance use and associated risk behaviors in a sample of young adult women in Mexico City. DESIGN AND METHODS: The present study uses a cross-sectional design to examine sexual abuse history among women who use illicit substances. Data collection consisted of a questionnaire administered through face-to-face interviews with 101 women who sought treatment for substance use in Mexico City. A bivariate analysis was used to examine women who experienced sexual abuse and those who did not. Odds ratio and relative risk were estimated. RESULTS: A total of 101 women were interviewed with an average age of 19.2 years. The average age of onset of drug use was 15.4 years. Among participants, 68% reported having been victims of sexual abuse and rape. The average age of reported sexual abuse was 12.2 years. Participants reported a high rate of polydrug use (32.7%), consuming more than two drugs. Sexual abuse was associated with detention by police for drugs, forced prostitution, and consumption of substances during pregnancy. DISCUSSION AND CONCLUSIONS: This study found that sexual abuse and rape were highly associated with substance abuse outcomes and associated risk behaviors.

Constructing Health State Descriptions for Low-Risk Thyroid Cancer: Stakeholder Engagement and Formative Qualitative Research.

OVERVIEW: This paper describes stakeholder involvement and formative qualitative research in the creation of health state descriptions (HSDs) or vignettes for low-risk thyroid cancer. The aim of this project was to engage stakeholders in the contribution of a novel set of HSDs, an important first step in the process of assessing value in thyroid cancer health states. METHODS: We draw upon formative, descriptive qualitative methods, following a multi-stage framework of data collection. We conducted individual semi-structured interviews, cognitive interviews, and focus groups with thyroid cancer patients, community providers, academic subspecialists, and participants with no thyroid cancer diagnosis (N = 31). The HSDs went through several iterations over the course of a year, in collaboration with a highly engaged community advisory board, laying the groundwork for HSDs that are comprehensible, comparable, and appropriate for stated-preference research. FINDINGS: Thyroid cancer survivors compared their experiences with those described in the HSDs. Feedback included concern for the emotional well-being of study participants who would be reading them. Providers were attuned to the need for clinical accuracy and made suggestions to reflect their clinical experience, including for patients with complications or disease progression. The pilot participants with no thyroid cancer were particularly valuable in promoting the need to simplify language and maximize readability. DISCUSSION: Stakeholder engagement was critical to being responsive to feedback as the iterations were refined and presented. Continuous engagement and consultation with multiple sources strengthened the HSDs. A secondary outcome from this project is that stakeholders expressed interest in adapting the HSDs into decision aids for people newly diagnosed with low-risk thyroid cancer.

Tibiotalocalcaneal nailing for osteoporotic ankle fractures in the frail patient: a narrative review with a clinical score proposal for the decision-making process.

Osteoporotic ankle fractures result from mechanical forces that would not ordinarily result in fracture, known as 'low-energy' trauma, such as those equivalent to a fall from a standing height or less. Osteoporotic ankle fractures in frail patients are becoming more and more frequent in daily practice and represent a therapeutic challenge for orthopaedic surgeons. The main problems with frail patients are the poor condition of the soft tissues around the ankle, dependence for activities of daily living and high comorbidity. The decision to operate on these patients is complex because conservative treatment is poorly tolerated in unstable fractures and conventional open reduction and internal fixation is associated with a high rate of complications. The authors conducted a narrative review of the literature on primary tibiotalocalcaneal nailing of ankle fractures in frail patients and categorized the different factors to consider when treatment is indicated for this conditon. Difficulty of ambulation, age over 65 years old, deteriorated baseline state and instability of the fracture were the most frequently considered factors. Finally, the authors propose an easy and quick clinical scoring system to help in the decision-making process, although further comparative studies are required to explore its validity.

[Penicillin allergy]. / Alergia a la penicilina.

Betalactams are the most widely used antimicrobials for their safety and efficacy. These include the penicillins, cephalosporins, carbapenems, and monobactams. Penicillin allergy ranks first in relation to drug allergy. 10 to 20 % of the population is labeled as allergic to it, often wrongly. Cross reaction is reported in 2 to 5 % between penicillins and cephalosporin. There is no cross reaction between penicillins and aztreonam, but there is with ceftazidime. All the mechanisms of the Gell and Coombs classification are included in the pathophysiology of hypersensitivity reactions to penicillin. Stratification according to risk allows us to take the most objective behavior to label the patient as allergic to. In the natural history of penicillin allergy, 80-90 % of patients lose this sensitivity by 10 years. If necessary, the patient can undergo a desensitization protocol. The immuno-allergist is a key piece in the selection of the patient, the elaboration of the challenge and desensitization protocols, in a controlled environment.

Los betalactámicos son los antimicrobianos más utilizados por su seguridad y eficacia. En este grupo se incluyen las penicilinas, las cefalosporinas, los carbapenémicos y los monobactámicos. La penicilina constituye la primera causa de alergia a medicamentos: 10 a 20 % de la población se etiqueta como alérgica a la misma, en muchas ocasiones erróneamente. Se ha reportado reacción cruzada entre penicilinas y cefalosporina en 2 a 5 %. No hay reacción cruzada entre penicilinas y aztreonam, pero sí con ceftazidima. En la fisiopatología de las reacciones de hipersensibilidad a penicilina se incluyen todos los mecanismos de la clasificación de Gell y Coombs. La estratificación de acuerdo con el riesgo permite tomar la decisión más objetiva para etiquetar al paciente como alérgico. En la evolución natural de la alergia a la penicilina, 80 a 90 % de los pacientes pierde dicha sensibilidad a los 10 años. De ser indispensable, el paciente puede ser sometido a un protocolo de desensibilización. El médico inmunoalergologo es una pieza clave en la selección del paciente, la elaboración de los protocolos de reto y la desensibilización en un ambiente controlado.

Use of Violence as a Strategy of Early Adolescents for Rejecting Drug Offers in Mexican Cities.

Drug use and violence are two interconnected problems in violent urban contexts, leading to coercive drug offers. In this study, relationships between drug use, use of violence as a strategy for rejecting drug offers, and exposure to neighborhood violence were analyzed in Mexican students. Data were obtained through a self-report survey and focus groups with lower secondary students in three Mexican metropolitan areas. Both quantitative and qualitative results indicated that students who had used or would use violence as a strategy for rejecting drug offers presented a more problematic psychosocial profile, with exposure to neighborhood violence as the main predictor. These results suggest that Mexican students in violent cities may resort to violence as a strategy for rejecting drug offers.

El consumo de drogas y la violencia son dos problemas interconectados en contextos urbanos violentos y generan ofrecimientos de drogas coercitivos. En este estudio se analizaron las relaciones entre el consumo de drogas, el uso de violencia como una estrategia para resistir ofrecimientos de drogas y la exposición a violencia en el barrio entre estudiantes mexicanos. Se obtuvieron los datos mediante una encuesta de autoinforme y grupos de discusión centrada con estudiantes de educación secundaria en tres áreas metropolitanas de México. Tanto los resultados cuantitativos como los cualitativos indicaron que aquellos estudiantes que habían usado o usarían violencia como una estrategia para resistir ofrecimientos de drogas presentaban un perfil psicosocial más problemático, con la exposición a violencia en el barrio como el principal predictor. Estos resultados sugieren que los estudiantes mexicanos en ciudades violentas pueden recurrir a la violencia como una estrategia para resistir ofrecimientos de drogas.

Revisiting a physiologically based pharmacokinetic model for cocaine with a forensic scope.

A whole-body permeability-rate-limited physiologically based pharmacokinetic (PBPK) model for cocaine was developed and adjusted with the pharmacokinetic data from studies with animals and reparametrized scaling to humans with the aim to predict the concentration-time profiles of the drug in blood and different tissues in humans. Estimated time course concentrations could be used as an interpretation tool by forensic toxicologists. The model estimations were compared successfully with pharmacokinetic parameters and time to peak for some effects reported in the literature. Once developed, the PBPK model was employed to predict the time course tissue concentrations reported in previous distribution studies introducing individualizing data. The heart and brain concentrations estimated by the model match adequately with the time and duration of some effects such as chronotropic and psychoactive effects, respectively. This work is the first attempt for employing PBPK modeling as a tool for forensic interpretation. Future modeling of other cocaine metabolite profiles or interaction when co-administered with other substances, such as alcohol, might be developed in the future.

Years of life lost (Yll) attributable to alcohol consumption in Mexico City.

The aim of this study was to estimate the YLL attributable to alcohol consumption in Mexico City from 2006 - 2012. Vital statistics on mortality attributable to alcohol consumption from the INEGI (Instituto Nacional de Estadística y Geografía) were used to determine YLL as well as the average age of death in relation to different age ranges by sex. A total estimate of 168,607 YLL was obtained, with an average loss of 18.32 years being observed for men and 17.54 years for women. Men accounted for a higher proportion of the YLL than women. According to the ICD-10 (Tenth Revision of International Classification of Diseases), liver disease attributable to alcohol consumption was found to be responsible for more than 80% of the total YLL. There was a cyclical trend in YLL from 2006 to 2012. The YLL attributable to alcohol suggest that alcohol consumption is a public health problem that involves losses in productivity and economic costs, and the decline in YLL could be explained by the decrease in income caused by the economic crisis of 2008, just as the increase could be explained by economic improvement in 2012.

Tratamiento mínimamente invasivo del síndrome de Wilkie / Minimally invasive management of Wilkie´s syndrome

Introducción. La compresión de la tercera porción del duodeno debido a la formación de un ángulo inadecuado de la unión aortomesentérica, se configura como el síndrome de arteria mesentérica superior o síndrome de Wilkie. Se trata de una entidad rara, de modo que es escaso su reporte en la literatura y poco aplicado su manejo quirúrgico mínimamente invasivo. Materiales y métodos. Se hace una revisión no sistemática de la literatura y posteriormente se expone el caso de un paciente con síndrome de Wilkie. Se muestran las imágenes de tomografías y un vídeo del procedimiento quirúrgico al que fue sometido. Discusión. El tratamiento quirúrgico del síndrome de la arteria mesentérica superior es el último recurso que se ofrece en pacientes con esta entidad. La duodenoyeyunostomía es el procedimiento con mejor evidencia en pacientes con compromiso severo del estado nutricional. Se describen los puntos esenciales de esta técnica utilizada en el caso que se reporta. Conclusiones. Cualquier entidad que cause la disminución del paquete graso entre la arteria mesentérica superior y la aorta puede causar síndrome de la arteria mesentérica superior. El diagnóstico es de exclusión y constituye un reto para el equipo médico. El tratamiento inicial es conservador, en tanto que la última opción es el manejo quirúrgico, idealmente por vía laparoscópica. Dentro de las técnicas mínimamente invasivas, la duodenoyeyunostomía es una buena herramienta

Introduction: Compression of the third portion of the duodenum due to an inappropriate angle of the aortamesenteric junction is known as the superior mesenteric artery syndrome or Wilkie's syndrome. A rare entity, reason why the reports in the literature are scarce and the minimally invasive surgical management is scarcely used. Materials and methods: A non-systematic review of the literature was carried out, and the case of a patient with Wilkie's syndrome is reported. The images, tomographies and a video of the surgical procedure are presented.Discussion: The surgical management of the superior mesenteric artery syndrome is the ultimate management to be offered in patients with this entity. Duodenojejunostomy is the procedure with the best evidence to be offered to patients with severe malnutrition. The essential points of this technique, used for the case reported, are described. Conclusions: Any entity that causes the reduction of the fatty pack between the superior mesenteric artery and the aorta can cause superior mesenteric artery syndrome. The diagnosis is made by exclusion and constitutes a challenge for the medical team. The initial treatment is conservative, and the last option is the surgical management, ideally laparoscopic; among the minimally invasive techniques, duodenojejunostomy is a good tool

Diseño de bitácora centrado en el residente: conociendo y mejorando la experiencia de usuario / Design of resident-centered surgical logbook: knowing and improving the user´s experience

Introducción. Las bitácoras quirúrgicas son poco y mal utilizadas en nuestro medio. Bien elaboradas, se convierten en una herramienta útil, tanto para el residente como para la universidad, que permite evaluar el desempeño y tomar medidas cuando se determine necesario. Método. Es un estudio descriptivo de corte transversal en el que se evaluó un antes y un después del uso de la bitácora Logbook como herramienta tecnológica para el registro de procedimientos quirúrgicos. Se hizo una encuesta previa y otra posterior a un periodo de prueba de un mes (abril 2017), y se obtuvieron datos sobre el uso personal de su bitácora y las calificaciones de la herramienta presentada. Resultados. Diecisiete residentes (R1-R4) contestaron la encuesta y participaron en la prueba piloto. Quince de ellos (88,2 %) llevaban bitácora, la gran mayoría de ellos en un medio electrónico. Ocho (50 % de los que la usaban) calificaron como "regular" la experiencia con la bitácora actual y todos estarían dispuesto a adoptar una nueva opción. Solo tres (17,6 %) sabían que el uso de la bitácora es obligatoria en su universidad. Diez (71,4 %) calificaron la herramienta como "excelente" y, cuatro (28,6 %), como "buena". Todos la recomiendan, la continuarían usando y dicen que la herramienta les facilita cumplir con la tarea. Durante el periodo de prueba, 17 médicos usuarios registraron 276 entradas. Discusión. Una herramienta adecuada logra un mejor cumplimiento de los residentes de cirugía, y les facilita una gestión rápida y eficaz de su información, lo que genera conocimiento de su proceso de formación. Hacen falta un periodo mayor y un grupo de estudiantes más amplio, para validar estos datos

Introduction: Surgical logbooks are under- and misused. When used appropriately, they can become helpful tools for both residents and universities, letting the evaluation of progress and performance, so as to take action when indicated. Methods: Cross-sectional, descriptive, observational study evaluating Logbook for surgical case logging. We conducted a pre- and post-test survey (April 2017), and the data obtained reflected how they used their current caselogs and how they graded ours. Results: 17 residents (PGY1-PGY4) took the surveys and used the platform during the test period. Fifteen of them (88.2%) actually registered their cases, mostly on an e-platform. Eight (50%) had an "average" experience with their current tool, and 100% would consider a different option. Only three (17.6%) know it's mandatory to register cases at their University. Ten (71.4%) and four (28.6%) graded our tool as "excellent" or "good". 100% would recommend it to peers, would continue using it and believe it makes them more adherent to registering. During the test period, we had 17 users, and 276 entries were registered. Discussion: An appropriate tool to register procedures allows a better residence adherence. This can be done in an easy and diligent way, so that residents can gain knowledge from their own progress. Larger number of residents and longer periods of time are needed in order to validate our results

Años de Vida Perdidos (AVP) atribuibles al consumo de alcohol en la ciudad de México / Years of life lost (Yll) attributable to alcohol consumption in Mexico city

Resumen El objetivo de este artículo es estimar los AVP atribuibles al consumo de alcohol en la Ciudad de México durante 2006 – 2012. Se utilizaron las estadísticas vitales de mortalidad del INEGI atribuibles al consumo de alcohol para obtener los AVP, se obtuvieron ademas promedios de edad de muerte respecto a intervalos de edad por sexo. Se estimaron 168,607 AVP, con una pérdida promedio de 18.32 años para los hombres y 17.54 en mujeres. Se encontró una mayor proporción de AVP en hombres que en mujeres. De acuerdo a la CIE-10 se observó que las enfermedades del hígado atribuibles al alcohol, aportan más del 80% de los AVP al total. Existe una tendencia cíclica en los AVP entre 2006 a 2012. Los AVP atribuibles al alcohol apuntan a que el consumo es un problema de salud pública que implican pérdidas en la productividad y costos económicos, mientras la baja en los AVP podría ser explicada por una disminución en el ingreso provocada por la crisis económica de 2008 al igual que el aumento por la mejoría en el 2012.

Abstract The aim of this study was to estimate the YLL attributable to alcohol consumption in Mexico City from 2006 – 2012. Vital statistics on mortality attributable to alcohol consumption from the INEGI (Instituto Nacional de Estadística y Geografía) were used to determine YLL as well as the average age of death in relation to different age ranges by sex. A total estimate of 168,607 YLL was obtained, with an average loss of 18.32 years being observed for men and 17.54 years for women. Men accounted for a higher proportion of the YLL than women. According to the ICD-10 (Tenth Revision of International Classification of Diseases), liver disease attributable to alcohol consumption was found to be responsible for more than 80% of the total YLL. There was a cyclical trend in YLL from 2006 to 2012. The YLL attributable to alcohol suggest that alcohol consumption is a public health problem that involves losses in productivity and economic costs, and the decline in YLL could be explained by the decrease in income caused by the economic crisis of 2008, just as the increase could be explained by economic improvement in 2012.

Asociación del consumo de sustancias psicoactivas con el cuidado y la salud del adulto mayor / Association of psychoactive substances use with care and health of older adults

Antecedentes El consumo de alcohol, tabaco y otras drogas tiene repercusiones importantes en la vida diaria de los adultos mayores. Con el objeto de conocer la asociación entre consumo de sustancias psicoactivas y variables de cuidado y salud en adultos mayores. Método Se recopiló información de una muestra aleatoria del padrón de usuarios del IAAM-DF. 2098 personas aceptaron participar y fueron entrevistadas en sus hogares, su tasa de respuesta fue de 83.9%. Resultados y discusión Se encontró que 13.1% requiere de ayuda en actividades básicas e instrumentales de la vida diaria; 81.4% percibe poco apoyo social; 82.2% señala pertenecer a una familia disfuncional, y a 45.5% le ha sido diagnosticada una enfermedad crónico-degenerativa. Mediante razón de momios se determinó que el consumo riesgoso de alcohol y la dependencia de éste por adultos mayores incrementan en ellos el riesgo de padecer enfermedades crónico-degenerativas, infecciosas y trastornos mentales, e influyen en su necesidad de recibir apoyo en actividades básicas e instrumentales de la vida diaria , así como en su percepción de disfunción familiar. El consumo de tabaco aumentó el riesgo de padecer enfermedades crónico-degenerativas e infecciosas, y se asocia con la percepción de salud y apoyo familiar. La ingestión de alguna droga, ilegal o prescrita, no se asoció significativamente con variables de cuidado, pero sí impacta en la aparición de enfermedades crónico-degenerativas y de trastornos mentales. Los resultados muestran que el consumo de alcohol, tabaco y otras drogas influye en la salud y el cuidado de los adultos mayores en la Ciudad de México, por lo cual constituye una tarea urgente atender estas problemáticas para mejorar la calidad de vida de éstos.

Background The use of alcohol, tobacco and other drugs have a significant impact on the daily lives of older adults. In order to study the relationship between substance use, health and care variables in older adults. Method Information was collected in a random sample of the registry users of the DF IAAM program; 2098 people agreed to participate and was interviewed in their homes, the response rate obtained was 83.9%. Results and discussion It was found that 13.1% receive aid in basic and instrumental activities of daily living, 81.4% perceived little social support, 82.2% perceived belonging to a dysfunctional family and 45.5% have been diagnosed with a chronic degenerative disease. Using odds ratios, it was shown that at-risk drinking and alcohol dependence increased the risk of chronic degenerative diseases, infectious and mental disorders and affects the need for support in basic and instrumental activities of daily living and perception of family dysfunction. Smoking increased risk of chronic degenerative and infectious diseases and also was associated with perceived health and family support. The use of any illegal or prescribed drugs was not significantly associated with care variables, but affect chronic degenerative diseases and mental disorders. The results of this study showed that use of alcohol, tobacco and other drugs affect the health and care of older adults in Mexico City, so it is urgent to address these problems in order to improve their quality of life.

Prevalencia y factores asociados al consumo de tabaco, alcohol y drogas en una muestra poblacional de adultos mayores del Distrito Federal / Prevalence and associated factors of use of tobacco, alcohol and drugs in elderly from Distrito Federal

There are no studies in Mexico estimating the use of psychoactive substances in the elderly (+69 yrs) and there is a lack of information about the risk factors determining the burden of disease for this age group. The goal of this study is to present prevalences of use of alcohol, tobacco, illicit drugs and nonmedical prescription drugs in beneficiaries of a cash supplement program sponsored by the Institute for the Care of Elderly from Federal District (Instituto para la Atención del Adulto Mayor del Distrito Federal, IAAM-DF). Furthermore, significant sociodemographic factors associated with substance use are reported. From a random sample of the 2 501 users registries of a cash supplement program of IAAM-DF, a total of 2 098 agreed to participate and were interviewed in their homes. The response rate was of 83.9%. We found that 63.5% of all participants ever used alcohol, 45.4% ever used tobacco and 3.5% ever used any drugs. Near one out of every two men and one out of every four women used alcohol during the previous 12 months, one out of every 10 older adults used tobacco and just one out of every 100 used any kind of drug in the last 12 months. Overall prevalence of substance use is higher in men, with the exception of medical drugs. Outstanding associated factors in substance use were sex and higher socioeconomic levels. This is the first study in the country on substance use in dwelling elderly, not living in institutions. Alcohol use, even risky drinking, is not uncommon, smoking tobacco habits do not disappear with age, and medical drug use can be of concern for its effects on other diseases. Therefore, it becomes necessary to establish definitions of risky use for this population and develop appropriate intervention programs for this population group.

No existen investigaciones en el país sobre uso de sustancias psico-activas en poblaciones de adultos mayores (+69 años) y se carece de información sobre los factores de riesgos que son determinantes para la carga de la enfermedad en este grupo. Este estudio tuvo como objetivo presentar las prevalencias de consumo de alcohol, tabaco, drogas ilícitas y drogas médicas usadas sin prescripción en los beneficiarios del programa de pensión alimentaria del Instituto para la Atención del Adulto Mayor del Distrito Federal (IAAM-DF). Adicionalmente, se reportaron factores sociodemográficos asociados al consumo de estas sustancias. De una muestra aleatoria del padrón de usuarios del programa del IAAM-DF de 2501 personas, un total de 2098 aceptaron participar y fueron entrevistadas en sus hogares, obteniéndose una tasa de respuesta de 83.9%. Se encontró que 65.3% de la población consumió alcohol, 45.4% tabaco y 3.5% alguna droga alguna vez en la vida. En los últimos 12 meses, casi uno de cada dos varones y una de cada cuatro mujeres consumió alcohol; uno de cada 10 adultos mayores consumió tabaco; y sólo uno de cada 100 consumió alguna droga. La prevalencia de consumo de sustancias es mayor en hombres, con excepción de las drogas médicas. Los factores asociados que destacaron fueron el sexo y los mejores niveles económicos. Éste es el primer estudio realizado en el país sobre uso de sustancias en población de adultos mayores con domicilio fijo, no institucionalizado. El consumo de alcohol, incluso el consumo riesgoso, no es infrecuente; el hábito tabáquico no ha desaparecido con la edad, y el uso de drogas médicas puede ser un motivo de preocupación por su efecto en otras patologías. Se hace necesario establecer definiciones de uso riesgoso para esta población y desarrollar programas de intervención adecuados para este grupo.

Tendencias del uso de drogas en la Ciudad de México: Encuesta de estudiantes, octubre 2012 / Drug use trends in Mexico City: 2012 students survey

Introducción Los estudios epidemiológicos en nuestro país muestran un incremento en el consumo de drogas ilegales y de alcohol. La edad de inicio también ha disminuido, especialmente en el consumo de alcohol. Por su parte, el consumo de inhalables se ha incrementado en forma importante, especialmente entre las mujeres jóvenes. Son diversos los factores asociados al consumo de drogas, pero de manera importante destacan el desarrollo de estrategias de resistencia, junto con sus habilidades sociales subyacentes, así como los estilos parentales de crianza. Método La presente es una encuesta probabilística en población escolar de secundarias y bachilleratos de la Ciudad de México que se levantó en noviembre del 2012, con representación a nivel de cada Delegación. La muestra fue de 26 503 alumnos. La información se obtuvo mediante un cuestionario estandarizado y validado en encuestas anteriores. Resultados El consumo de tabaco disminuyó significativamente (de 44.3% a 41.0%), el 32.9% de los adolescentes comenzó a utilizar tabaco antes de los 13 años. El 68.2% consumió alcohol alguna vez; en tanto que la edad de inicio promedio de consumo de esta sustancia se mantuvo en los 12.6 años. La prevalencia de consumo de drogas alguna vez aumentó de 21.5% a 24.4%. La mariguana es la droga de preferencia en la población estudiantil (15.9%). También se encontraron incrementos en la presencia de abuso sexual, mientras que el intento suicida disminuyó. Discusión Los resultados muestran el continuo crecimiento que tiene esta problemática, aunque los inhalables se mantuvieron constantes y el tabaco disminuyó de manera importante. Dado estos resultados, es una tarea preponderante dedicar más esfuerzos a la prevención con estudios e intervenciones evaluadas para preescolar y primaria, así como para los padres de familia y los maestros.

Introduction Epidemiological studies in our country show increases in the consumption of illegal drugs and alcohol. The age of onset has decreased, especially regarding alcohol use. Meanwhile, consumption of inhalants has increased significantly, especially among young women. There are several factors associated with drug use, but the development of resistance strategies, along with its underlying social skills and parenting styles, stand out in a significant way. Method Data comes from a probabilistic survey carried out in November 2012, with students from 7th to 12th school grades, in Mexico City, which was representative for each of its districts. The sample was 26 503 students. Information was obtained through a questionnaire standardized and validated in previous surveys. Results Tobacco consumption decreased significantly (44.3% to 41.0%); 32.9% of the adolescents began its use before age 13. Lifetime consumption of alcohol was 68.2%, while the average age of onset of cannabis use remained at 12.6 years. Lifetime prevalence of any drug use increased from 21.5% to 24.4%. Marijuana was the first drug of choice among students (15.9%). Increases were also found in sexual abuse rate, while suicide attempt decreased. Discussion Although inhalants use remained stable and tobacco use decreased significantly, results show the continued growth of drug use. Given this context, concentrating more efforts in prevention with studies and evaluated interventions for pre-school and elementary school students, as well as for parents and teachers, is a preponderant task.

Ablación de úterosacros por videolaparoscopia, una alternativa en dismenorrea primaria incapacitante / Ablation of uterosacral ligaments by video laparoscopy. A resource in primary, incapacitating dysmenorrhea

En la dismenorrea incapacitante se han utilizado múltiples tratamientos médicos y quirúrgicos, de ellos la ablación de ligamentos úterosacros es la que ha tenido una mejor respuesta. El objetivo del estudio es demostrar la utilidad de la ablación de los ligamentos úterosacros como tratamiento en la dismenorrea primaria incapacitante. Se efectúo un estudio prospectivo, longitudinal, de una cohorte, en el cual las pacientes fueron sus propios controles. La muestra de trabajo de tipo no probabilístico se integró por 15 pacientes del servicio de ginecología, que se encontraban en estudio por dismenorrea primaria incapacitante y que habían recibido tratamiento médico mínimo de tres meses, sin respuesta favorable al mismo, habiéndose descartado patología pélvica. Se les realizó videolaparoscopia diagnóstica, se utilizó como medio de distensión CO2, para revisión pélvica, lente de 10 mm, gran angular, marca Storz y corriente monopolar para ablación de úterosacros cuando no existió otra patología asociada. Su seguimiento fue de 6 a 16 meses, calificándose la respuesta al dolor dismenorreico en ausente, leve, moderado y severo; considerándose éxito cuando el dolor permitió la actividad diaria al pasar de severo a leve, etc. Se utilizó X2 a un nivel de significancia de p 0.05. En relación al dolor se observó que uno (7 por ciento) permaneció asintomática, nueve (50 por ciento) se transformó en leve, tres (20 por ciento) en mdoerada y dos (13 por ciento) permaneció sin cambio. Al comparar las diferencias pre y post tratamiento fueron estadísticamente significativas a una P 0.0025 a favor de la mejoría de la dismenorrea. Concluimos que no obstante que se trata de una muestra pequeña, los resultados son alentadores ya que cualquier grado de mejoría observado beneficia a nuestras pacientes para la realización de su actividad diaria normal