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1.
Blocking the dimerization of polyglutamine-expanded androgen receptor protects cells from DHT-induced toxicity by increasing AR turnover.
J Biol Chem
; 300(5): 107246, 2024 May.
Article
in English
| MEDLINE | ID: mdl-38556081
2.
A phenotypically robust model of spinal and bulbar muscular atrophy in Drosophila.
J Neurosci Res
; 102(1): e25278, 2024 01.
Article
in English
| MEDLINE | ID: mdl-38284836
3.
Fluorescence Imaging of Huntingtin mRNA Knockdown.
Bioconjug Chem
; 29(4): 1276-1282, 2018 04 18.
Article
in English
| MEDLINE | ID: mdl-29451775
4.
Proteasome-mediated proteolysis of the polyglutamine-expanded androgen receptor is a late event in spinal and bulbar muscular atrophy (SBMA) pathogenesis.
J Biol Chem
; 290(20): 12572-84, 2015 May 15.
Article
in English
| MEDLINE | ID: mdl-25795778
5.
Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy.
Hum Mol Genet
; 23(5): 1376-86, 2014 Mar 01.
Article
in English
| MEDLINE | ID: mdl-24150846
6.
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation.
Nat Chem Biol
; 9(2): 112-8, 2013 Feb.
Article
in English
| MEDLINE | ID: mdl-23222885
7.
A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability.
Hum Mol Genet
; 21(19): 4225-36, 2012 Oct 01.
Article
in English
| MEDLINE | ID: mdl-22736030
8.
ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor.
Nat Med
; 13(3): 348-53, 2007 Mar.
Article
in English
| MEDLINE | ID: mdl-17334372
9.
Differentially disrupted spinal cord and muscle energy metabolism in spinal and bulbar muscular atrophy.
JCI Insight
; 9(7)2024 Mar 05.
Article
in English
| MEDLINE | ID: mdl-38452174
10.
Differentiating PC12 cells to evaluate neurite densities through live-cell imaging.
STAR Protoc
; 4(1): 101993, 2023 03 17.
Article
in English
| MEDLINE | ID: mdl-36602900
11.
Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice.
iScience
; 26(8): 107375, 2023 Aug 18.
Article
in English
| MEDLINE | ID: mdl-37599829
12.
SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA.
J Neurosci
; 31(48): 17425-36, 2011 Nov 30.
Article
in English
| MEDLINE | ID: mdl-22131404
13.
The role of ubiquitination in spinal and bulbar muscular atrophy.
Front Mol Neurosci
; 15: 1020143, 2022.
Article
in English
| MEDLINE | ID: mdl-36277484
14.
Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy.
Acta Neuropathol Commun
; 10(1): 97, 2022 07 05.
Article
in English
| MEDLINE | ID: mdl-35791011
15.
An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.
J Biol Chem
; 285(46): 35567-77, 2010 Nov 12.
Article
in English
| MEDLINE | ID: mdl-20826791
16.
Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy.
Hum Mol Genet
; 18(11): 1937-50, 2009 Jun 01.
Article
in English
| MEDLINE | ID: mdl-19279159
17.
Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy.
J Clin Invest
; 131(1)2021 01 04.
Article
in English
| MEDLINE | ID: mdl-33170804
18.
Molecular Mechanisms and Therapeutics for SBMA/Kennedy's Disease.
Neurotherapeutics
; 16(4): 928-947, 2019 10.
Article
in English
| MEDLINE | ID: mdl-31686397
19.
Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy.
Sci Rep
; 9(1): 119, 2019 01 15.
Article
in English
| MEDLINE | ID: mdl-30644418
20.
The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms.
Front Mol Neurosci
; 10: 159, 2017.
Article
in English
| MEDLINE | ID: mdl-28596723