Subject(s)

Abnormalities, Multiple/genetics , Abnormalities, Multiple/therapy , Genes, ras , Abnormalities, Multiple/physiopathology , Chondroitin Sulfates/metabolism , Craniofacial Abnormalities/genetics , Enzyme Inhibitors/therapeutic use , Farnesyltranstransferase/antagonists & inhibitors , Genotype , Germ-Line Mutation , Heart Defects, Congenital/genetics , Human Growth Hormone/therapeutic use , Humans , Neoplasms/genetics , Phenotype , Syndrome