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Purpose@#This study aimed to evaluate the effectiveness of exercise in patients with hemophilia. @*Methods@#We carried out a systematic review and meta-analysis in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines. A literature search was conducted of published randomized controlled trials for exercise interventions from January 1, 2014 to March 15, 2023. To estimate the size of the effects of exercise, a meta-analysis was performed using the R package “meta.” @*Results@#Five databases were searched to obtain articles published in Korean or English. Of 1,150 articles reviewed, 13 were included in the systematic review and 9 in the meta-analysis. The risk of bias was assessed using RoB 2.0. Results: The overall effect sizes of exercise interventions, calculated as the standardized mean difference, were -0.11 (95% confidence interval [CI] = -1.41 to –1.20) for pain, -2.13 (95% CI = -3.33 to -0.93) for joint health, 9.96 (95% CI = 7.51 to 12.28) for physical activity, and 0.59 (95% CI = -0.39 to -1.56) for quality of life. @*Conclusion@#These findings suggest that exercise is useful for improving the joint health and physical activity of patients with hemophilia. Thus, it is necessary to develop and apply exercise interventions for patients with hemophilia to reduce their pain and improve their quality of life.
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Purpose@#This study aimed to update the previously published nursing practice guideline for prevention of venous thromboembolism (VTE). @*Methods@#The guideline was updated according to the manuals developed by National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN), and a Handbook for Clinical Practice Guideline Developer Version 10. @*Results@#The updated nursing practice guideline for prevention of VTE was consisted of 16 domains, 46 subdomains, and 216 recommendations. The recommendations in each domain were: 4 general issues, 8 assessment of risk and bleeding factors, 5 interventions for prevention of VTE, 18 mechanical interventions, 36 pharmacological interventions, 36 VTE prevention starategies for medical patients, 25 for cancer patients, 13 for pregnancy, 8 for surgical patients, 7 for thoractic and cardiac surgery, 16 for orthopedic surgery, 10 for cranial and spinal surgery, 5 for vascular surgery, 13 for other surgery, 3 educations and information, and 2 documentation and report. For these recommendations, the level of evidence was 32.1% for level I, 51.8% for level II, and 16.1% for level III according to the infectious diseases society of America (IDSA) rating system. A total of 112 new recommendations were developed and 49 previous recommendations were deleted. @*Conclusion@#The updated nursing practice guideline for prevention of VTE is expected to serve as an evidence-based practice guideline for prevention of VTE in South Korea. It is recommended that this guideline will disseminate to clinical nursing settings nationwide to improve the effectiveness of prevention of VTE practice.
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Purpose@#The goal of this study was to see how different aerobic exercise intensities affected AMP-activated protein kinase (AMPK), reactive oxygen, and antioxidant enzymes in young mice during an 8-week period. @*Methods@#Forty male C57BL/6 mice, aged seven weeks, were randomly assigned to one of four groups: control (n = 10), low-intensity exercise (n = 10), moderate-intensity exercise (n = 10), and high-intensity exercise (n = 10). For eight weeks, aerobic activity was performed once a day for 35–40 minutes, five days a week. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), chi-squared tests, and the Tukey test in the SPSS/WIN 25.0 program. @*Results@#Weight (p = .001) was substantially different between the moderate-intensity exercise group and the control group in AMPK (p < .001). In addition, there were no significant differences between the moderate-intensity exercise group and the control group in reactive oxygen malondialdehyde (MDA) levels (p = .136) and antioxidant enzyme superoxide dismutase (SOD) levels (p = .521). @*Conclusion@#These findings suggest that moderate-intensity aerobic exercise increased AMPK activation and helped young mice shed weight.
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Purpose@#The goal of this study was to see how different aerobic exercise intensities affected AMP-activated protein kinase (AMPK), reactive oxygen, and antioxidant enzymes in young mice during an 8-week period. @*Methods@#Forty male C57BL/6 mice, aged seven weeks, were randomly assigned to one of four groups: control (n = 10), low-intensity exercise (n = 10), moderate-intensity exercise (n = 10), and high-intensity exercise (n = 10). For eight weeks, aerobic activity was performed once a day for 35–40 minutes, five days a week. The data were analyzed using descriptive statistics, analysis of variance (ANOVA), chi-squared tests, and the Tukey test in the SPSS/WIN 25.0 program. @*Results@#Weight (p = .001) was substantially different between the moderate-intensity exercise group and the control group in AMPK (p < .001). In addition, there were no significant differences between the moderate-intensity exercise group and the control group in reactive oxygen malondialdehyde (MDA) levels (p = .136) and antioxidant enzyme superoxide dismutase (SOD) levels (p = .521). @*Conclusion@#These findings suggest that moderate-intensity aerobic exercise increased AMPK activation and helped young mice shed weight.
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Purpose@#To determine effects of family conflict mitigation documentary programs on conflicts, autonomic nerve activation (ANA), and happiness of elderly in long-term care hospitals. @*Methods@#This study used a non-equivalent control group with a pretest-posttest design. It was conducted on 39 elderly patients (19 in the experimental group and 20 in the control group) in long-term care hospitals. The experimental group (n = 19) received family conflict mitigation documentary programs. The family conflict mitigation documentary programs consisted of four sessions (40-50 minutes per session). These programs were implemented in small groups, with each group having five elderly. Data were analyzed by sing the conflict checklist, the Oxford Happiness Questionnaire, Chi-square test with Fisher’s exact test, independent t-test, paired t-test, and repeated measure ANOVA using the SPSS/WIN 21.0 program. @*Results@#The participants in the experimental group showed significantly decreased scores of conflict (t = -2.31, p = .028) and the value of sympathetic nervous system activity (t = 8.36, p = .007) compared with those of the control group. The participants in the experimental group showed significantly increased the value of parasympathetic nervous system activity (t = -2.91, p = .008) and scores of happiness (t = 5.46, p < .001). @*Conclusion@#The family conflict mitigation documentary programs on conflicts, ANA, and happiness of the elderly in long-term care hospitals are effective intervention programs for mitigating conflicts between elderlies and their families and for improving happiness of the elderly in long-term care hospitals.
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Purpose@#To determine effects of family conflict mitigation documentary programs on conflicts, autonomic nerve activation (ANA), and happiness of elderly in long-term care hospitals. @*Methods@#This study used a non-equivalent control group with a pretest-posttest design. It was conducted on 39 elderly patients (19 in the experimental group and 20 in the control group) in long-term care hospitals. The experimental group (n = 19) received family conflict mitigation documentary programs. The family conflict mitigation documentary programs consisted of four sessions (40-50 minutes per session). These programs were implemented in small groups, with each group having five elderly. Data were analyzed by sing the conflict checklist, the Oxford Happiness Questionnaire, Chi-square test with Fisher’s exact test, independent t-test, paired t-test, and repeated measure ANOVA using the SPSS/WIN 21.0 program. @*Results@#The participants in the experimental group showed significantly decreased scores of conflict (t = -2.31, p = .028) and the value of sympathetic nervous system activity (t = 8.36, p = .007) compared with those of the control group. The participants in the experimental group showed significantly increased the value of parasympathetic nervous system activity (t = -2.91, p = .008) and scores of happiness (t = 5.46, p < .001). @*Conclusion@#The family conflict mitigation documentary programs on conflicts, ANA, and happiness of the elderly in long-term care hospitals are effective intervention programs for mitigating conflicts between elderlies and their families and for improving happiness of the elderly in long-term care hospitals.
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Purpose@#This study used a mixed methods research design in an attempt to verify the effects of robot-assisted rehabilitation on the gait ability of stroke patients with hemiplegia, and thereby further understand the benefits and challenges of stroke patients’ experiences relying on robot-assisted rehabilitation. @*Methods@#An exploratory sequential mixed methods study design was used in order to combine both quantitative and qualitative data. For the quantitative data collection, a total of 30 stroke patients with hemiplegia were recruited from one rehabilitation hospital. Qualitative data were collected through individual interviews using semi-structured questionnaires for a group of 15 patients who were currently undergoing robot-assisted rehabilitation. The data were analyzed through qualitative content analysis. @*Results@#As a result of the quantitative analysis, there were significant differences between the two groups in terms of daily living activity patterns, total number of steps, and average walking speed. As a result of the qualitative analysis, the four main themes derived consisted of, ‘curiosity about the usage of robot-assisted rehabilitation,’ ‘pleasure experienced while using the robots,’ ‘insufficient information about robots,’ and ‘a lack of education about robot-assisted rehabilitation.’ @*Conclusions@#Robot-assisted rehabilitation had a significant effect on the walking ability of stroke patients with hemiplegia. Additionally, stroke patients with hemiplegia experienced difficulty during the course of their robot-assisted rehabilitation, due to a lack of sufficient information on correct usage techniques. These quantitative and qualitative findings could provide the basic foundation for the development of an educational program on robot-assisted rehabilitation.
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Purpose@#This study was conducted to examine the effects of an educational program based on mobile SMS and counseling for colonoscopy in elderly people. Methods: The study utilized a non-equivalent control group with a non-synchronized design as a quasiexperimental research. The study subjects consisted of 72 elderly people (36 elderly people in the experimental group and 36 in the control group). Among the subjects, 49 were male (68.1%) and 23 were female (31.9%), and the age was 69.04± 6.14 years. Fortyfive subjects (62.5%) answered that they had underlying diseases, eight subjects (11.1%) had a family history of colon disease, and 61 subjects (84.7%) had undergone a colonoscopy. The experimental group was provided with an educational program based on mobile SMS and counseling when three days and one day before the test. The control group received verbal explanations using information sheet. The data were analyzed using descriptive statistics, the Chi-squares test, and the independent t-test with SPSS/WIN 21.0. @*Results@#Significant differences were found in bowel cleanliness scores (t= 3.60, p= .003) between the groups. No significant differences were seen between the groups in the sedation drug dosage (propofol (t= 1.02, p= .730), midazolam (t= 0.66, p= .380)) and time for colonoscopy (t= 1.08, p= .235). Conclusion: Based on the results of this study, an educational program based on mobile SMS and counseling for colonoscopy was proposed as an educational program before colonoscopy.
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Purpose@#The study was conducted to investigate the correlation between perception of patient safety risk factors, patient safety competency, and safety nursing activities of nurses in hemodialysis units and identify factors affecting patient safety activities. @*Methods@#The participants were 146 nurses from 16 hemodialysis units located in Gyeongsangnam-do. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA, Pearson correlation coefficient, and multiple regression analysis using the SPSS, version 24.0. @*Results@#The mean safety nursing activity score was 3.47±0.38. safety nursing activities of the participants were significantly correlated with patient safety competency. The characteristics showing significant differences in safety nursing activities were educational level, hospital type, hospital work experience, number of hemodialysis treatment per day, number of hemodialysis treatment per nurse, educational experience of patient safety, presence of a patient safety incident report registration system, and direct registration of patient safety incident report. The multiple regression analysis revealed that the factors influencing safety nursing activities were patient safety incident report, patient safety competency, and number of daily hemodialysis treatment (<5~7 times/day) per nurse (R2 =.34). @*Conclusion@#The results of this study suggest that the safety nursing activities of hemodialysis unit nurses should be intensified. In addition, the registration system of patient safety incident report and nurses’ competency on patient safety should be improved, and the number of hemodialysis per nurse should be fewer than 7 times per day.
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Purpose@#The study was conducted to investigate the correlation between perception of patient safety risk factors, patient safety competency, and safety nursing activities of nurses in hemodialysis units and identify factors affecting patient safety activities. @*Methods@#The participants were 146 nurses from 16 hemodialysis units located in Gyeongsangnam-do. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA, Pearson correlation coefficient, and multiple regression analysis using the SPSS, version 24.0. @*Results@#The mean safety nursing activity score was 3.47±0.38. safety nursing activities of the participants were significantly correlated with patient safety competency. The characteristics showing significant differences in safety nursing activities were educational level, hospital type, hospital work experience, number of hemodialysis treatment per day, number of hemodialysis treatment per nurse, educational experience of patient safety, presence of a patient safety incident report registration system, and direct registration of patient safety incident report. The multiple regression analysis revealed that the factors influencing safety nursing activities were patient safety incident report, patient safety competency, and number of daily hemodialysis treatment (<5~7 times/day) per nurse (R2 =.34). @*Conclusion@#The results of this study suggest that the safety nursing activities of hemodialysis unit nurses should be intensified. In addition, the registration system of patient safety incident report and nurses’ competency on patient safety should be improved, and the number of hemodialysis per nurse should be fewer than 7 times per day.
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Purpose@#The purpose of this study was to investigate the actual utilization of clinical practice guidelines developed by Hospital Nurses Association. @*Methods@#The subjects were 70 nurses who were in charge of guideline distributions in 70 advanced general hospital and general hospitals with 500 beds or more nationwide.Data were collected between June and August, 2020 by mail (return rate: 88.6%). Data were analyzed using descriptive statistics, t-test, and ANOVA with SPSS/WIN 24.0. @*Results@#Among the clinical practice guidelines developed by Hospital Nurses Association, 72.9~90.1% were placed with book and electronic file in nursing department and 24.3~35.8% were placed with book and electronic file in each nursing unit at hospital. The average number of utilized clinical practice guidelines were 3.96±3.88, and average score of guideline utilization was score 2.85±0.79 which means ‘use sometimes’. @*Conclusion@#To improve the distribution and utilization of the clinical practice guidelines, it is necessary to enhance the recognition of values of evidence based nursing practice targeting head of nursing department and to stimulate the distribution and utilization of the clinical practice guidelines using diverse education programs for staff nurses.
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Purpose@#The purpose of this study is to construct and validate a posttraumatic growth structural model for firefighters based on Calhoun and Tedeschi’s model (2006). @*Methods@#The research data was collected from 200 firefighters working in Gyeongsang-do, Jeolla-do, and Gyeonggi-do. The participants completed an anonymous survey asking about ego-resilience, active coping, family support, organizational support, self-exposure, deliberate rumination, posstraumatic stress and posttraumatic growth. @*Results@#The model selected as a final model was the one that supports 10 hypotheses out of 13 hypotheses. In the final model, deliberate rumination (β=.59, p<.001) had a significant effect in the posttraumatic growth of firefighters. Active coping, organizational support, self-exposure, ego-resilience and posttraumatic stress had a significant indirect effect. The explanatory power of these variables was 36.0%. @*Conclusion@#The results of the survey show that it is important to develop a strategy to strengthen deliberate rumination. In addition, encouraging deliberate rumination through organizational support and self-exposure can promote posttraumatic growth of firefighters.
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Purpose@#Carbapenemase-producing Enterobacteriaceae (CPE) are associated with considerable mortality. This study was aimed to identify survival factors among medical care unit patients with CPE. @*Methods@#We conducted a retrospective cohort; data were collected from September 2017 to June 2019 through electronic medical records. The data collected were general characteristics, disease-related characteristics, severity-related characteristics, and treatment-related characteristics. Data were analyzed based on frequency, mean, standard deviation, Chi-square test, Fisher’s exact test, t-test, Pearson’s correlation coefficient, and Cox proportional hazard model using SPSS/WIN 21.0 program. @*Results@#Seventy-seven patients were included (59 survivors and 18 deceased) in the study. Univariate analysis identified factors for survival associated with acquired CPE as age (t= -1.56, p= .037), simplified acute physiology 3 (SAPS3) score of admission date (t= -2.85, p= .006), Glasgow coma scale (GCS) of CPE acquisition date (t= 2.38, p= .020), artery catheter at CPE acquisition date (χ2 = 4.58, p= .032), vasoconstrictor agents use at CPE acquisition date (χ2 = 6.81, p= .009), platelet at CPE acquisition date (t= 2.27, p= .025), lymphocyte at CPE acquisition date (t= 2.01, p= .048), calcium at CPE acquisition date (t= 2.68, p= .009), albumin at CPE acquisition date (t= 2.29,p= .025), and creatinine at CPE acquisition date (t= 2.24, p= .028). Multivariate Cox proportional hazard model showed that GCS at CPE acquisition date (HR= 1.14, 95% CI= 1.05-1.22), lymphocyte at CPE acquisition date (HR= 1.05, 95% CI= 1.00-1.10), and creatinine at CPE acquisition date (HR= 1.25, 95% CI= 1.04-1.49) were independent survival factors among medical intensive care unit patients with CPE. @*Conclusion@#Based on the study results, it is necessary to develop nursing interventions that can aid in the management of patients with CPE and identify their effects.
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Purpose@#The purpose of this study is to construct and validate a posttraumatic growth structural model for firefighters based on Calhoun and Tedeschi’s model (2006). @*Methods@#The research data was collected from 200 firefighters working in Gyeongsang-do, Jeolla-do, and Gyeonggi-do. The participants completed an anonymous survey asking about ego-resilience, active coping, family support, organizational support, self-exposure, deliberate rumination, posstraumatic stress and posttraumatic growth. @*Results@#The model selected as a final model was the one that supports 10 hypotheses out of 13 hypotheses. In the final model, deliberate rumination (β=.59, p<.001) had a significant effect in the posttraumatic growth of firefighters. Active coping, organizational support, self-exposure, ego-resilience and posttraumatic stress had a significant indirect effect. The explanatory power of these variables was 36.0%. @*Conclusion@#The results of the survey show that it is important to develop a strategy to strengthen deliberate rumination. In addition, encouraging deliberate rumination through organizational support and self-exposure can promote posttraumatic growth of firefighters.
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Purpose@#The purpose of this study was to determine the effects of different intensity of aerobic exercise for four weeks on cardiovascular risk factors, reactive oxygen, and antioxidant enzymes in old mice. @*Methods@#Eighteen male C57BL/6 mice age 18 months were randomly classified into the control group (n=6), the moderate intensity exercise group (n=6), and the low intensity exercise group (n=6). The training groups performed the aerobic exercise twice daily for 20 minutes, five days weekly for four weeks. Data were analyzed using descriptive statistics, analysis of variance (ANOVA), the Chi-square test, and the Tukey’s test with the SPSSWIN 21.0 program. @*Results@#In this study, among the risk factors of cardiovascular disease, blood sugar (BS) (p=.023) and total cholesterol (TC) (p=.001) were significantly different between the moderate intensity exercise group and the control group. Additionally, there were significant differences in the reactive oxygen malondialdehyde (MDA) (p=.001), the antioxidant enzymes superoxide dismutase (SOD) (p<.001) and glutathione reductase (GR) (p=.015) between the moderate intensity exercise group and the control group. @*Conclusion@#This finding suggests that moderate intensity aerobic exercise promotes the activity of antioxidant enzymes and lowers cardiovascular risk factors in older mice.
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Purpose@#The purpose of this study was to identify related factors in the organizational socialization of new nurses, focusing on the reality shock of new nurses and social support by education specialist nurses. @*Methods@#Participants were 122 new nurses with clinical experience of 1 year or less as nurses working in a general hospital that is carrying out a pilot project for a new nurse training system. Data were collected using self-report questionnaires which included identification of participants' characteristics, social support of education specialist nurse, reality shock and organizational socialization. @*Results@#The organizational socialization score was 3.07±0.45 points. The results of the stepwise multiple regression showed that factors affecting organizational socialization of new nurses were social support by gender, education specialist nurse and reality shock. These three variables accounted for 72.0% of organizational socialization. @*Conclusion@#These findings suggest that the social support of education specialist nurses be enhanced to increase the organizational socialization of new nurses. There is also a need for a program to decreased the reality shock of new nurses.
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Purpose@#The purpose of this study was to identify related factors in the organizational socialization of new nurses, focusing on the reality shock of new nurses and social support by education specialist nurses. @*Methods@#Participants were 122 new nurses with clinical experience of 1 year or less as nurses working in a general hospital that is carrying out a pilot project for a new nurse training system. Data were collected using self-report questionnaires which included identification of participants' characteristics, social support of education specialist nurse, reality shock and organizational socialization. @*Results@#The organizational socialization score was 3.07±0.45 points. The results of the stepwise multiple regression showed that factors affecting organizational socialization of new nurses were social support by gender, education specialist nurse and reality shock. These three variables accounted for 72.0% of organizational socialization. @*Conclusion@#These findings suggest that the social support of education specialist nurses be enhanced to increase the organizational socialization of new nurses. There is also a need for a program to decreased the reality shock of new nurses.
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PURPOSE: This study was conducted to examine the effect of a Happiness Self-Coaching program for new graduate nurses working in cancer care units. METHODS: A quasi-experimental pretest-posttest, nonequivalent control-group design was applied to conduct the study. Study participants were new graduate nurses employed within 12 months and working as shift employees at G university hospital, located in J city. A total of 21 new graduate nurses participated in the study, 10 in the experimental group, and 11 in the control group. The happiness self-coaching program was conducted weekly for 70 minutes from February 1 to June 6, 2016 for 6 weeks. The experimental group received the Happiness Self-Coaching program through lectures, presentation, group activities, and strength card play. Data were analyzed by using repeated measure ANOVA and paired t-test. RESULTS: The experimental group demonstrated significantly higher happiness (F=6.82, p=.003) and self-efficacy (F=3.38 p=.045) levels compared to the control group.
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Happiness , Lecture , Nursing , Oncology Service, Hospital , Self EfficacyABSTRACT
PURPOSE: This study was conducted to examine the effects walking program with dance on gait, cognition, and risk of falls of elderly with dementia in a long-term care hospital. METHODS: Subjects consisted of 42 elderly with dementia in a long-term care hospital (21 elderly with dementia in an experimental group and 21 elders with dementia in a control group). Data were collected from March 14 to April 30, 2016. Subjects in the experimental group performed walking program with dance (three times a week, 30–50 minutes session, 18 sessions). Data were analyzed using descriptive statistics, Chi-square test, Fisher's exact test, independent t-test, paired t-test, repeated measures ANOVA with the SPSS/WIN 21.0. RESULTS: The participants in the experimental group showed significantly increased scores of cadence (F=8.36, p=.007) and improved scores of cognition (F=9.95, p=.003) compared the control group. CONCLUSION: The findings indicate walking program with dance is recommend a regular exercise program to enhance the cadence associated with walking speed and cognitive function elderly.
Subject(s)
Aged , Humans , Accidental Falls , Cognition , Dancing , Dementia , Gait , Long-Term Care , WalkingABSTRACT
PURPOSE: This study was conducted to examine the effects of a telephone-based self-management support program led by nurses on self-care behavior, biological index for cardiac function, and depression. METHODS: This study is a quasi-experiment in nonequivalent control group design. Thirty-eight heart failure patients underwent medical treatment at the hospital (18 heart failure patients in the experimental group and 20 heart failure patients in the control group). The experimental group (n = 18) received the telephone-based self-management support program, which included a 30-minute face-to-face education session and four telephone consultation and education sessions. The face-to-face education session was conducted at the first visit to the outpatient clinic. Thereafter, weekly telephone consultations and education sessions were performed for 4 weeks. Data were analyzed using descriptive statistics, Chi-square test, Fisher's exact test, independent t test, paired t test, and repeated measures analysis of variance using the SPSS/WIN 21.0. RESULTS: The participants in the experimental group showed significantly increased self-care behavior scores (t = 6.65, p < .001), decreased N-terminal pro-brain natriuretic peptide level (U= −2.28, p = .022), improved left ventricular ejection fraction values (t = 2.24, p = .032), and decreased depression scores (t = −3.49, p = .001) compared with the control group. CONCLUSION: The findings indicate that the telephone-based self-management program is an effective intervention to improve self-management in heart failure patients.