1.
Acta Haematol Pol
; 22(1): 92-9, 1991.
Article
in Polish
| MEDLINE
| ID: mdl-1823972
ABSTRACT
The appearance of antibodies to factor VIII is a serious complication in the treatment of haemophilia A. A protocol is presented aiming at suppression of the anticoagulant using continued treatment with factor VIII (25 u/kg b.w. twice weekly). Ten patients with previous maximal factor VIII antibody titre from 7 to 2900 Bethesda units were treated. So far the inhibitor was eradicated in 3 cases treated continuously for from 5 to 20 months. In two of these three cases successful surgical procedures were performed without anamnestic response.
Subject(s)
Autoantibodies/immunology , Autoimmune Diseases/immunology , Blood Transfusion , Factor VIII/administration & dosage , Factor VIII/immunology , Fibrinogen/administration & dosage , Hemophilia A/immunology , Adolescent , Adult , Autoimmune Diseases/blood , Autoimmune Diseases/therapy , Child , Hemophilia A/blood , Hemophilia A/therapy , Humans , Immune Tolerance/immunology , Male , Middle Aged
2.
Wiad Lek
; 24(17): 1643-7, 1971 Sep 01.
Article
in Polish
| MEDLINE
| ID: mdl-5116437