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1.
Whole body and local hyperthermia enhances the photosensitizing efficacy of 3-[(1'-hexyloxy)ethyl]-3-Devinylpyropheophorbide-a (HPPH).
Lasers Surg Med
; 50(5): 506-512, 2018 07.
Article
in English
| MEDLINE | ID: mdl-29737551
2.
Measurement of Cyanine Dye Photobleaching in Photosensitizer Cyanine Dye Conjugates Could Help in Optimizing Light Dosimetry for Improved Photodynamic Therapy of Cancer.
Molecules
; 23(8)2018 Jul 24.
Article
in English
| MEDLINE | ID: mdl-30042350
3.
Effect of Metalation on Porphyrin-Based Bifunctional Agents in Tumor Imaging and Photodynamic Therapy.
Bioconjug Chem
; 27(3): 667-80, 2016 Mar 16.
Article
in English
| MEDLINE | ID: mdl-26735143
4.
Effect of chirality on cellular uptake, imaging and photodynamic therapy of photosensitizers derived from chlorophyll-a.
Bioorg Med Chem
; 23(13): 3603-17, 2015 Jul 01.
Article
in English
| MEDLINE | ID: mdl-25936263
5.
Regioselective synthesis and photophysical and electrochemical studies of 20-substituted cyanine dye-purpurinimide conjugates: incorporation of Ni(II) into the conjugate enhances its tumor-uptake and fluorescence-imaging ability.
Chemistry
; 19(21): 6670-84, 2013 May 17.
Article
in English
| MEDLINE | ID: mdl-23526622
6.
Multifunctional nanoplatforms for fluorescence imaging and photodynamic therapy developed by post-loading photosensitizer and fluorophore to polyacrylamide nanoparticles.
Nanomedicine
; 8(6): 941-50, 2012 Aug.
Article
in English
| MEDLINE | ID: mdl-22115602
7.
Photodynamic Therapy in Combination with Doxorubicin Is Superior to Monotherapy for the Treatment of Lung Cancer.
Biomedicines
; 10(4)2022 Apr 06.
Article
in English
| MEDLINE | ID: mdl-35453607
8.
Tumor-Avid 3-(1'-Hexyloxy)ethyl-3-devinylpyrpyropheophorbide-a (HPPH)-3Gd(III)tetraxetan (DOTA) Conjugate Defines Primary Tumors and Metastases.
J Med Chem
; 65(13): 9267-9280, 2022 07 14.
Article
in English
| MEDLINE | ID: mdl-35763292
9.
Impact of mono- and di-ß-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy.
Eur J Med Chem Rep
; 52022 Aug.
Article
in English
| MEDLINE | ID: mdl-36568335
10.
Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics with enhanced tumor-imaging and photosensitizing (PDT) efficacy.
Mol Pharm
; 8(4): 1186-97, 2011 Aug 01.
Article
in English
| MEDLINE | ID: mdl-21702452
11.
Synthesis, spectroscopic, and in vitro photosensitizing efficacy of ketobacteriochlorins derived from ring-B and ring-D reduced chlorins via pinacol-pinacolone rearrangement.
J Org Chem
; 76(21): 8629-40, 2011 Nov 04.
Article
in English
| MEDLINE | ID: mdl-21955163
12.
Chiral Alkyl Groups at Position 3(1') of Pyropheophorbide-a Specify Uptake and Retention by Tumor Cells and Are Essential for Effective Photodynamic Therapy.
J Med Chem
; 64(8): 4787-4809, 2021 04 22.
Article
in English
| MEDLINE | ID: mdl-33822622
13.
Synthesis, Tumor Specificity, and Photosensitizing Efficacy of Erlotinib-Conjugated Chlorins and Bacteriochlorins: Identification of a Highly Effective Candidate for Photodynamic Therapy of Cancer.
J Med Chem
; 64(1): 741-767, 2021 01 14.
Article
in English
| MEDLINE | ID: mdl-33400524
14.
Hexylether derivative of pyropheophorbide-a (HPPH) on conjugating with 3gadolinium(III) aminobenzyldiethylenetriaminepentaacetic acid shows potential for in vivo tumor imaging (MR, Fluorescence) and photodynamic therapy.
Bioconjug Chem
; 21(5): 828-35, 2010 May 19.
Article
in English
| MEDLINE | ID: mdl-20387862
15.
Synthesis of Tumor-avid Photosensitizer-Gd(III)DTPA conjugates: impact of the number of gadolinium units in T1/T2 relaxivity, intracellular localization, and photosensitizing efficacy.
Bioconjug Chem
; 21(5): 816-27, 2010 May 19.
Article
in English
| MEDLINE | ID: mdl-20387863
16.
Pluronic F-127: An Efficient Delivery Vehicle for 3-(1'-hexyloxy)ethyl-3-devinylpyropheophorbide-a (HPPH or Photochlor).
Photochem Photobiol
; 96(3): 625-635, 2020 05.
Article
in English
| MEDLINE | ID: mdl-31738460
17.
The Structures of Gd(III) Chelates Conjugated at the Periphery of 3-(1'-Hexyloxy)ethyl-3-devinylpyropheophorbide-a (HPPH) Have a Significant Impact on the Imaging and Therapy of Cancer.
ChemMedChem
; 15(21): 2058-2070, 2020 11 04.
Article
in English
| MEDLINE | ID: mdl-32916033
18.
Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors.
Biomolecules
; 10(12)2020 12 09.
Article
in English
| MEDLINE | ID: mdl-33317162
19.
Highlights on the imaging (nuclear/fluorescence) and phototherapeutic potential of a tri-functional chlorophyll-a analog with no significant toxicity in mice and rats.
J Photochem Photobiol B
; 211: 111998, 2020 Oct.
Article
in English
| MEDLINE | ID: mdl-32862090
20.
Compared to purpurinimides, the pyropheophorbide containing an iodobenzyl group showed enhanced PDT efficacy and tumor imaging (124I-PET) ability.
Bioconjug Chem
; 20(2): 274-82, 2009 Feb.
Article
in English
| MEDLINE | ID: mdl-19191565