ABSTRACT
The nonlinear groundwater level fluctuations depend on the interaction of many factors such as evapotranspiration, precipitation, groundwater abstraction, and hydrogeological characteristics, making groundwater level prediction a complex task. Groundwater level changes are among the most critical issues in water resource management, which can be predicted to effectively provide management solutions to conserve renewable water resources. Understanding the aquifer status using numerical models is time-consuming and also is associated with inherent uncertainty; therefore, in recent decades, the application of artificial intelligence methods to predict water table fluctuations has significantly gained momentum. In this study, artificial neural network (ANN), fuzzy logic (FL), adaptive neuro-fuzzy inference system (ANFIS), and least square support vector machine (SVM) methods were utilized to predict groundwater level (GWL) with 1-, 2-, and 3-month lead time in Tehran-Karaj plain. Several input scenarios were developed considering groundwater levels, average temperature, total precipitation, total evapotranspiration, and average river flow on a monthly interval. The four error criteria, the correlation coefficient (R), root mean squared error (RMSE), Nash-Sutcliffe efficiency (NSE), and mean absolute error (MAE), were the basis to evaluate the models. Results showed that all the applied methods could provide acceptable GWL prediction, but the ANFIS was the most accurate. However, the ANFIS model showed slightly better performance by yielding R = 0.98 for the training stage and R = 0.98 for the testing stage in the P84 observation well and the second combination of inputs and 1-month lead time. The outcomes also revealed that all the approaches mentioned above could appropriately predict GWL for the leading time of 1 and 2 months, but the models provided unsatisfactory results for a 3-month leading time.
Subject(s)
Artificial Intelligence , Groundwater , Environmental Monitoring/methods , Fuzzy Logic , Iran , RiversABSTRACT
This paper presents the results of an assessment about interaction between Urmia Lake (UL) and coastal groundwater in the Urmia aquifer (UA). This aquifer is the most significant contributor to the freshwater supply of the coastal areas. The use of hydrochemical facies can be very useful to identify the saltwater encroachment or freshening phases in the coastal aquifers. In this study, the analysis of salinization/freshening processes was carried out through the saturation index (SI), ionic deltas (Δ), binary diagrams, and hydrochemical facies evolution (HFE) diagram. Based on the Gibbs plot, the behavior of the major ions showed that the changes in the chemical composition of the groundwater are mainly controlled by the water-soil/rock interaction zone and few samples are relatively controlled by evaporation. A possible explanation for this phenomenon is that the deposited chloride and sulfate particles can form the minor salinity source in some coastal areas when washed down by precipitation. The SI calculations showed that all groundwater samples, collected in these periods, show negative saturation indices, which indicate undersaturation with respect to anhydrite, gypsum, and halite. In addition, except in a few cases, all other samples showed the undersaturation with respect to the carbonate minerals such as aragonite, calcite, and dolomite. Therefore, these minerals are susceptible to dissolution. In the dry season, the SI calculations showed more positive values with respect to dolomite, especially in the northern part of UA, which indicated a higher potential for precipitation and deposition of dolomite. The percentage of saltwater in the groundwater samples of Urmia plain was very low, ranging between 0.001 and 0.79 % in the wet season and 0.0004 and 0.81 % in the dry season. The results of HFE diagram, which was taken to find whether the aquifer was in the saltwater encroachment phase or in the freshening phase, indicated that except for a few wells near the coast, there is very little hydraulic interaction between UA and UL. In this coastal area, most of the samples that were collected repeatedly in both wet and dry seasons showed the same hydrochemical facies, which suggested that the seasonal groundwater fluctuations cannot significantly change the chemical composition of groundwater.
Subject(s)
Groundwater/chemistry , Salinity , Water Pollutants/analysis , Chlorides/analysis , Environmental Monitoring/methods , Iran , Sulfates/analysis , Water Supply/statistics & numerical dataABSTRACT
Up to now, there is no any experience about the application of dental lasers to bond resin composites to metal surfaces in dentistry. The aim of this preliminary study was to evaluate if the laser irradiation of ceramic-covered alloy surface would improve the bond strength of resin to metal, and if different parameters of laser output may influence the strength of this bond. Fifty three cylinders (thickness of 5 mm and diameter of 10 mm) were made up of a commercially available nickel-chromium alloy by lost-wax technique. Forty prepared specimens were divided into four groups. Five specimens in each group were covered by slurry of dental opaque porcelain and irradiated by Nd:YAG laser using different output parameters for each group. Other five specimens in each group were treated using the same laser parameters without porcelain covering. Five sandblasted specimen served as control group. Panavia F2.0 was bonded on the metal surfaces using polyethylene tubes. In ceramic-coated specimens, silane was applied to achieve chemical bond between silica particles and resin cement. All specimens were thermocycled and subjected to shear bond strength (SBS) test (50 kgf at 0.5 mm/min). Two specimens of each ceramic-coated laser-treated groups were studied using scanning electron microscopy and wavelength dispersive X-ray spectroscopy which showed stabilization of silica particles on the metal surface. ANOVA procedure showed that although shear bond strength was significantly higher in porcelain-covered laser treated samples, but the effect of power output of laser irradiation was not significant (P = 0.917). There were no statistically significant difference between SBS in control samples and laser treated specimens without porcelain covering. It can be concluded that Nd:YAG laser surface treatment may improve the silica coating of alloy surface to achieve better resin-metal bond.
Subject(s)
Dental Alloys/chemistry , Dental Bonding/methods , Dental Porcelain/chemistry , Lasers, Solid-State , Resin Cements/chemistry , Analysis of Variance , Bisphenol A-Glycidyl Methacrylate/chemistry , Chromium , Microscopy, Electron, Scanning , Nickel , Spectrometry, X-Ray Emission , Surface PropertiesABSTRACT
The ability of clinoptilolite zeolite as a filter in water wells to remove lead from polluted groundwater was tested in batch and fixed-bed column experiments. XRF, XRD, SEM, and BET were used to characterize the zeolite. Because of the pH variation in groundwater, batch experiments were performed at pH = 6, 7, and 8, with the highest removal efficiency (84.2%) at pH = 6 and 298 K within 90 min. The Freundlich model accurately predicted metal ion adsorption behavior and indicated a multilayer adsorption of Pb(II) molecules on the inhomogeneous surface of clinoptilolite. The best-fitting kinetic model for clinoptilolite is the pseudo-second order equation, highlighting that the rate of adsorption is dependent on absorbent capacity. Next, the effect of flow rate, bed depth, and grain size of clinoptilolite on lead removal was investigated in column experiments at an initial concentration of 450 mg pb/L. The highest removal efficiency was achieved in column experiments with a flow rate of 1 mL/min, a bed height of 10 cm, and a grain size of 0.6 to 0.8 mm. Breakthrough curves were predicted by the Thomas and Yoon-Nelson models, with excellent agreement with the corresponding experimental data. This research will be used to develop a new in situ remedial approach for removing lead from polluted groundwater.
Subject(s)
Groundwater , Water Pollutants, Chemical , Water Purification , Zeolites , Zeolites/chemistry , Lead , Water Wells , Feasibility Studies , Water Pollutants, Chemical/chemistry , AdsorptionABSTRACT
Accurate and precise values of hydrodynamic parameters are needed for groundwater modeling and management. Pumping test in the aquifer is the standard method to estimate the transmissivity, hydraulic conductivity, and storage coefficient as the key hydrodynamic parameters. Analytical solutions with curve matching and numerical modeling are two methods to estimate these parameters in the aquifer. Graphical analyses are commonly applied to time-drawdown/water table data which are time-consuming and approximate. Graphical type-curve methods as promising tools are used extensively in water resources studies, while applying these methods is still new in pumping test analysis. In the current study, the first effort based on our knowledge, we have reviewed the literature type-curve graphical methods in pumping test analysis. To achieve this goal, we reviewed and compared the journal articles regarding the characteristics and capabilities of the modeling process from 2000 to 2022. We have clustered the reviewed papers into graphical, modeling, and hybrid categories. Then, a comprehensive review of the selected papers was presented to delineate the highlight of every paper. This review could guide researchers in pumping test analysis. Also, we have presented various recommendations for future research to improve the quality of hydrodynamic parameter estimation.
Subject(s)
Groundwater , Water Resources , Electric Conductivity , Hydrodynamics , Models, Theoretical , Water MovementsABSTRACT
Coronavirus disease 2019 (COVID-19) infection, which was initially reported in Wuhan, China, in December 2019, had a rapid spread throughout the world becoming a new global crisis. Today, very little is known about neonatal COVID-19 infection. Herein, we tried to define the clinical and demographic characteristics, risk factors, and laboratory and imagining findings of neonates who tested positive for COVID-19 and were admitted to the NICU (neonatal intensive care unit) of Ali Ibn Abi Taleb Hospital, Zahedan, Iran, from June 2021 to July 2021. All full-term and premature neonates diagnosed with COVID-19 were included in the study. Their ages ranged from 1 to 21 days at admission, including 6 boys and 4 girls. The medical records of mother-baby dyads were reviewed. All mothers, except for one, were negative for COVID-19 infection. The most frequent findings in the neonates were fever, poor feeding, respiratory distress, cough, hypoxemia, and drooling. Broad-spectrum antibiotics were administered as routine. All neonates, except for one, needed respiratory support, and intratracheal surfactant was administered for three newborns. Three neonates with severe disorders died during the study period.
ABSTRACT
BACKGROUND: Covid-19 patients suffer from psychiatric disorders too. The present study was designed to investigate the rate of psychiatric consultation requests in a general hospital. Reasons for consultation requests, types of psychiatric diagnoses, and factors in consultation requests were also investigated. METHODS: This cross-sectional study included all patients admitted with Covid-19 and referred to psychiatric consultation service in a major Covid-19 center in Tehran, Iran (2020). After acceing patients' electronic files, records of patients' demographic information, positive psychiatric symptoms, past psychiatric history and DSM5 diagnoses were made. Statistical analyses were done in SPSS 26 using descriptive statistics and chi-square and Fisher's exact test (p<0.05). RESULTS: Out of 1791 Covid-19 hospitalized patients, 132 patients (7.3%) had been referred to psychiatric consultation service. The most common reason for requests were restlessness and aggression (23.5%). Meanwhile, 92.4% of the patients were diagnosed to suffer from at least one psychiatric disorder including insomnia (64%), delirium (30.3%), anxiety due to hypoxia (15.3%) and generalized anxiety disorder (10.6%). CONCLUSION: Although studies report a high prevalence of psychiatric disorders in Covid-19 patients, requests for psychiatric consultations and consideration of psychiatric disorders are still remarkably low. The most common disorders appeared to be insomnia, delirium and anxiety.
Subject(s)
COVID-19 , Delirium , Sleep Initiation and Maintenance Disorders , Humans , Cross-Sectional Studies , Iran/epidemiology , Referral and Consultation , CounselingABSTRACT
Municipal wastewater irrigation induces elevated concentrations of heavy metals in the soil which their further leaching leads to groundwater contamination in the long run. In this study, both column experiment and 5-year prediction modeling using HYDRUS-1D were conducted to investigate the probable adsorption and transport of 10 different metals including As, Ba, Cr, Cu, Mo, Ni, Pb, Rb, Sr, and Zn in an alkaline soil from Nazarabad plain in Iran which has been irrigated with treated urban wastewater for several years. The obtained results revealed that reaching the equilibrium rate for the mentioned elements during 1825 days (= 5 years) was as follows: Mo > Cr > Rb > Zn > Ni > Ba> Sr > Pb > As> Cu. The finding implies that molybdenum (Mo) and copper (Cu) are the most mobile and the most adsorbent heavy metals in the soil, respectively. Higher mobility poses the greater potential risk of leaching into groundwater resources. Overall, experimental and numerical modelings had good accordance and were capable of describing the actual condition.
Subject(s)
Groundwater , Wastewater , Iran , LaboratoriesABSTRACT
The concentration of total dissolved mercury (HgT) in surface and groundwater resources in the coastal parts of Urmia aquifer (NW of Iran) was investigated to identify the possible sources and sinks of mercury and the geochemical mechanisms controlling its mobilization. The distribution of water samples on the Piper diagram demonstrates that most samples have the Ca-Mg-HCO3 facies. From 62 water samples collected in this area, one sample contained HgT concentrations exceeding the maximum contaminant level recommended by the WHO (6 µg/L). The principal component analysis (PCA) produced five principal components. The positive moderate correlation of HgT with EC, Cl, K, Mg, and Na indicated that the weathering of geological formations was one of the main sources of mercury in groundwater samples. Position of water samples in Eh-pH regions where microorganisms involved in mercury methylation and mineralization were potentially active demonstrated that the aquifer had undergone sulfate reduction and had reached the final stage of the terminal electron accepting process (TEAP) sequence in the methane production processes which are limited to only 37% of the water samples that have anaerobic conditions. Some Hg-bearing species are in nonequilibrium geochemical conditions. The supersaturation of water samples with magnetite and goethite indicated that these Fe-bearing minerals could act as the strong reducing agents for the reduction of Hg(II) to Hg(0).
Subject(s)
Groundwater , Mercury , Water Pollutants, Chemical , Environmental Monitoring , Environmental Pollution , Geology , Iran , Mercury/analysis , Water Pollutants, Chemical/analysisABSTRACT
The aim of the present study is to investigate the trend of suicide and its attempt and the factors related to completed suicide during a 5-year period (2014-2019) in South Khorasan province, Iran. Data analysis was performed using chi-square, independent t-test and backward logistic regression in SPSS ver. 16. Cochran-Armitage test was used to evaluate the trends of suicide attempt and completed suicide. P-value < 0.05 was considered as the significance level. There was a significantly higher rate of suicide attempt among women and a significantly higher rate of completed suicide among men (p = 0.007). The incidence of suicide attempt (p = 0.001) and suicide deaths (p = 0.003) have also increased significantly during these years and the most common method of suicide attempt is drug poisoning. Also increasing age, rural residence, having a history of mental disorder, marital separation and lower level of education led to a significant increase in the rate of completed suicide (p < 0.001). The present study showed no significant relationship between the history of suicide attempt and completed suicide (p = 0.19). The rate of suicide attempt was higher among women and the rate of completed suicide was higher among men. The rate of suicide attempts and completed suicides has increased during these five years. Factors such as untreated mental disorders, living in rural areas, separation, and older age were considered as risk factors for completed suicide. On the other hand, higher education level has played a protective role in this regard.
Subject(s)
Suicide, Attempted , Suicide, Completed , Aged , Female , Humans , Incidence , Iran/epidemiology , Male , Risk FactorsABSTRACT
Knowledge of soil water dynamics in the deep vadose zone provides valuable information on the temporal and spatial variability of groundwater recharge. However, semi-arid climate can complicate how the input of water, such as irrigation, can contribute to potential groundwater recharge. This study assessed the recharge rates and their timing under irrigated cropland from a semi-arid region of northern Iran. A deep drainage (10 m) experiment was performed and in situ soil water content was measured to analyze the soil water dynamics and model hydraulic parameters using HYSDRUS-1D. The best parameters selected from inverse parameter optimization were used to calibrate model and estimate the long-term (20-year) average groundwater recharge and the influence of the root zone, unsaturated zone and the time scale on the recharge processes. The simulated annual flux ranged from 24 mm to 268 mm (mean of 110 mm) at 2-m depth and ranged between 26 mm to 207 mm (mean of 95 mm) at the 10-m depth. High fluxes, observed between December and April, may be the result of greater precipitation combined with the irrigation return flow. The May-October period showed a gradual decrease in flux at the depth of 2 m. At the depth of 10 m, the flux showed some continuity (base flux) during the long-term recharge simulation. In total, 12.7% of the input water contributed to the recharge of the groundwater. The annual soil water fluxes were almost similar irrespective of depth below the root zone and the flux rates did not show any clear relation between the different components of the water budget at any depth. This approach improved our understanding of the recharge process in the deep vadose zone in a semiarid region and can help for the development of effective management of groundwater resources.
ABSTRACT
BACKGROUND: Transient tachypnea of the newborn (TTN) is one of the most frequent causes of respiratory distress in neonates. A relationship has been shown between vitamin D deficiency and respiratory disorders in neonates. This research was carried out to evaluate the serum level of vitamin D in TTN newborns and their mothers compared to the control group. METHODS: This case-control research was conducted during 2016-2019 in a general hospital affiliated with Mashhad University of Medical Sciences, Iran. Thirty-four infants with TTN and 82 neonates in the control group as well as their mothers were investigated. The levels of umbilical cord serum vitamin D in infants with TTN and also their mothers were compared to the control group. RESULTS: The mean levels of serum vitamin D in infants with TTN and their mothers were 8.11 ± 4.32 and 12.6 ± 10.12 ng/mL, respectively (P<0.001), whereas they were 19.21 ± 12.71 and 25.96 ± 16.6 ng/mL in the newborns of the control group and their mothers, respectively (P<0.001). The mean differences (95% CI) of neonatal and maternal vitamin D level between the two groups were 11.10 (7.92-14.28) and 13.36 (7.90-18.08), respectively. In the TTN group, 100% of the infants had vitamin D levels less than 30 ng/mL (79.4% had severe, 17.6% had moderate and 2.9% showed mild deficiency). However, vitamin D levels lower than 30 ng/mL were observed in 76.4% of the neonates in the control group (28.8% had severe, 31.1% showed moderate and 16.3% had a mild deficiency) (P<0.001). CONCLUSION: The serum vitamin D levels of infants with TTN and their mothers were significantly lower than the control group. Therefore, TTN in infants may be reduced through the treatment of vitamin D deficiency in mothers.
Subject(s)
Fetal Blood , Transient Tachypnea of the Newborn/blood , Vitamin D Deficiency/blood , Adult , Case-Control Studies , Delivery, Obstetric/statistics & numerical data , Female , Humans , Incidence , Infant, Newborn , Iran/epidemiology , Male , Respiratory Distress Syndrome, Newborn/blood , Respiratory Distress Syndrome, Newborn/epidemiology , Respiratory Distress Syndrome, Newborn/etiology , Transient Tachypnea of the Newborn/epidemiology , Transient Tachypnea of the Newborn/etiology , Vitamin D/metabolism , Vitamin D Deficiency/epidemiologyABSTRACT
Leakage of hydrocarbon fuel (light nonaqueous-phase liquid, LNAPL) from petroleum processing facilities and storage tanks may result in significant subsurface contamination. Remediating the contaminated areas represent considerable challenges, especially when remediation resources are limited and site data are incomplete. A reasonable management strategy under this scenario may be to identify sites where LNAPL recovery operations should be located that would provide the largest LNAPL recovery initially while minimizing the LNAPL remaining in the subsurface (entrapped and residual LNAPL), which may serve as future sources for groundwater contamination. To accomplish this objective, we use estimates of subsurface recoverable and total LNAPL specific volumes and LNAPL transmissivities to generate GIS maps that can be combined to highlight locations where to develop LNAPL recovery operations. When the approach is applied to a LNAPL-contaminated area in Iran, we were able to narrow the locations for potential LNAPL recovery operations. Specifically, we combine maps of the LNAPL specific yield, an introduced term, and the LNAPL transmissivity where the LNAPL specific yield is the ratio of the recoverable to total LNAPL specific volumes. The LNAPL specific yield is a relative measure of the amount of LNAPL that potentially can be recovered while minimizing residual LNAPL in soils. The approach can be applied to sites where the recoverable and total LNAPL specific volumes and LNAPL transmissivities can be estimated using data from boreholes in the contaminated area.
Subject(s)
Oil and Gas Industry , Waste Disposal, Fluid/methods , Water Pollutants, Chemical/analysis , Forecasting , Groundwater , Hydrocarbons/analysis , Iran , Soil , Water WellsABSTRACT
This study aims to shed light on the seasonal behavior of yttrium and rare earth elements (YREEs) in the Urmia Aquifer (UA), in the immediate vicinity of Urmia Lake (UL) in Iran. Samples of groundwater, collected under dry and wet conditions in coastal wells of UA, suggest a large degree of variability in both YREE abundance and normalized patterns. Although weathering or water-rock interactions (between the surface/groundwater and rock samples) were predicted to be the most probable source in explaining YREEs in groundwater samples, results to the contrary indicate that the groundwater do not inherit aquifer rock-like YREE signatures in the study area; this might be due to the relative stability of YREEs during the process of water-rock interactions, which suggest that methods based on YREEs can be beneficial in discrimination of water sources. Furthermore, findings demonstrated no significant relationship between Ce/Ce* and salinity (0.08 and 0.05 in wet and dry seasons, respectively), and between Eu/Eu* and salinity (0.1 and -0.04 in wet and dry seasons, respectively). Dissimilarity of patterns of YREEs in rock and water samples reveals YREEs as no conservative tracers in determining the UL saltwater intrusion into coastal groundwater. Therefore, the groundwater YREE concentrations and fractionation patterns in UA warrant controlling by coastal aquifer need to be controlled by other chemical weathering, adsorption, desorption, and solution complexation reactions. Finally, comparison of REE concentration values in groundwater samples with corresponding indicative admissible drinking water concentrations (IAC) demonstrated their suitability for drinking purposes.
Subject(s)
Environmental Monitoring/methods , Groundwater/chemistry , Lakes/chemistry , Water Pollutants, Chemical/analysis , Yttrium/analysis , Adsorption , Iran , Metals, Rare Earth/analysis , SalinityABSTRACT
Amyloid ß (Aß) sheets aggregations is the main reason of Alzheimer disease. The interacting areas between monomers are residue number 38 to 42. Inhibition of interaction between Aß molecules prevents plaque formation. In the present study, we have performed a high-throughput virtual screening among ZINC database and top 1000 hits were checked again regarding binding affinity by AutoDock software. Top 4 successive second step screening hits was considered for drug design purpose against aggregation site of Aß molecules. The toxicity and pharmacological properties of new designed ligands was assessed by PROTOX and FAFdrugs3 webservers. Several steps of modifications performed in the structures of hit#1 and hit#2 and finally new designed ligand based on hit 1, 1-RD-3 (3-[(Z)-6-Hydroxy-4-{[5-(2-methoxyethyl)-6-methyltetrahydro-2H-pyran-2-yl]methyl}-1-methyl-3-hexenyloxy]tetrahydro-2Hpyran- 4-ol) and a designed ligand based on hit 2, 2-RD-2 (6-(Hydroxymethyl)-4-{5-hydroxy-6-methyl-4-[(3- methylcyclohexyl)methyl]tetrahydro-2H-pyran-2-yloxy}tetrahydro-2H-pyran-2,3,5-triol) could successfully pass pharmacological filters. The LD50 of 37000 mg/kg for 1-RD-3 and 2000 mg/kg for 2-RD-2 indicates that the designed ligands can be considered as new candidates for anti Aß aggregation to treat Alzheimer's disease. Interestingly, after performing several modification steps still a considerable binding affinity of -9.3 kcal/mol for 1-RD-3 and -9.8 kcal/mol for 2-RD-2 still remained. Theoretically, the new designed molecules can reduce the deposition of Aß in the cerebral cortex and as the results the Alzheimer symptoms could be decreased.
ABSTRACT
Measurements of major ions, trace elements, water-stable isotopes, and geophysical soundings were made to examine the interaction between Urmia Aquifer (UA) and Urmia Lake (UL), northwest Iran. The poor correlation between sampling depth and Cl(-) concentrations indicated that the position of freshwater-saltwater interface is not uniformly distributed in the study area, and this was attributed to aquifer heterogeneities. The targeted coastal wells showed B/Cl and Br/Cl molar ratios in the range of 0.0022-2.43 and 0.00032-0.28, respectively. The base-exchange index (BEI) and saturation index (SI) calculations showed that the salinization process followed by cation-exchange reactions mainly controls changes in the chemical composition of groundwater. All groundwater samples are depleted with respect to δ(18)O (-11.71 to -9.4 ) and δD (-66.26 to -48.41 ). The δ(18)O and δD isotope ratios for surface and groundwater had a similar range and showed high deuterium excess (d-excess) (21.11 to 31.16 ). The high d-excess in water samples is because of incoming vapors from the UL mixed with an evaporated moisture flux from the Urmia mainland and incoming vapors from the west (i.e., Mediterranean Sea). Some saline samples with low B/Cl and Br/Cl ratios had depleted δ(18)O and δD. In this case, due to freshwater flushing, the drilled wells in the coastal playas and salty sediments could have more depleted isotopes, more Cl(-), and consequently smaller B/Cl and Br/Cl ratios. Moreover, the results of hydrochemical facies evolution (HFE) diagram showed that because of the existence fine-grained sediments saturated with high density saltwater in the coastal areas that act as a natural barrier, increasing the groundwater exploitation leads to movement of freshwaters from recharge zones in the western mountains not saltwater from UL. The highly permeable sediments at the junction of the rivers to the lake are characterized by low hydraulic gradient and high hydraulic conductivity. These properties enhance the salinization of groundwater observed in the study area. The main factors influencing the salinity are base-exchange reactions, invasion of highly diluted saltwater, dissolution of salty pans, and water chemistry evolution along flow paths.
Subject(s)
Environmental Monitoring/methods , Groundwater/chemistry , Lakes/chemistry , Salinity , Water Pollutants/analysis , Iran , Isotopes , Mediterranean Sea , Rivers , Water ResourcesABSTRACT
OBJECTIVE: Neurological manifestations of neonatal disorders have various causes, among them neonatal tetanus, albeit rare, is a potentially fatal and preventable disease, which is seen in underdeveloped and developing countries. Although the disease has been eradicated from I.R. Iran, pregnant women immigrating to Iran from neighboring countries, especially from eastern border, may carry a risk of neonatal tetanus to the child due to inadequate tetanus immunization and inappropriate post-delivery care. It is then important to maintain a high index of suspicion for early diagnosis and prompt treatment, when infants present with poor feeding and abnormal behavior. Case presentation Here, we report the clinical course of a newborn with neonatal tetanus, who was admitted with complaints of poor feeding and muscle rigidity, more than a decade after eradication of the disorder.
ABSTRACT
We conducted this single blind randomized clinical trial to compare the efficacy and safety of oral chloral hydrate and intranasal midazolam for induction of sedation for computerized tomography scan of brain in children. Participants aged 1-10 years (n=60) were randomized to receive 100 mg/kg chloral hydrate orally with intra nasal normal saline OR intranasal midazolam 0.2 mg/kg with oral normal saline. Adequate sedation (Ramsay sedation score of four) was obtained and CT scan completed successfully in 76.7% of chloral hydrate group and in 40% of midazolam group (P=0.004). No significant difference was seen for side effects frequency between the two drugs (10% in chloral hydrate, 3.3% in midazolam group; P=0.34). We conclude that oral chloral hydrate can be considered as a safe and effective drug for sedation in children undergoing CT scan of brain.
Subject(s)
Chloral Hydrate/administration & dosage , Conscious Sedation/methods , Hypnotics and Sedatives/administration & dosage , Midazolam/administration & dosage , Tomography, X-Ray Computed/methods , Administration, Intranasal , Administration, Oral , Child, Preschool , Chloral Hydrate/adverse effects , Female , Humans , Hypnotics and Sedatives/adverse effects , Infant , Male , Midazolam/adverse effects , Neuroimaging , Single-Blind MethodABSTRACT
Despite an increasing prevalence of obesity and hypertension in young age, there is limited information on the contribution of body mass index (BMI) to blood pressure (BP) in these populations, especially in developing countries. This study examines the association between BMI and BP in four populations of school age children across southern region of Islamic republic of Iran.