ABSTRACT
OBJECTIVE OF THE STUDY: To see the different age groups, gender, sites, disease stage, treatment outcome of various oral cavity sites carcinoma by combined modalities and the overall treatment duration. MATERIALS AND METHODS: A total of 212 oral cavity carcinoma patients (169 males and 43 females) with complete records (from September 2009 to December 2012) were analyzed for age, sex, histopathology, associated medical illnesses, various subsites with disease stage, various treatment modalities with the duration and follow-up records for disease control as well as disease failure at local, nodal, local + nodal, and distant metastasis. RESULTS: The most common site in oral cavity cancer was buccal mucosa 81 (38.20%). 149 (69%) patients reported were in advanced Stages III and IV of the disease. The majority of patients 149 (70.28%) were given chemotherapy + radiotherapy postoperatively (S-CRT group). The mean follow-up for all patients was 41 months (range = 21-59 months). In terms of overall disease control and metastases-free survival, the best results were (80%) for Stage I in all oral cavity sites. Irrespective of disease stage best results (59.57%) were in alveolar ridge subsite of oral cavity carcinoma. CONCLUSION: Challenges are still lie ahead in treating head and neck carcinoma, as in spite of using multimodality treatment approach and biological and molecular research, the overall survival percentage has not changed much. In India as oral cavity carcinoma is in increasing trend in younger individuals massive health promotion and awareness programs targeting the risk population along with financial support for those already affected are required.
Subject(s)
Mouth Neoplasms/therapy , Adult , Aged , Aged, 80 and over , Female , Humans , India , Male , Middle Aged , Retrospective Studies , Survival Analysis , Treatment Outcome , Young AdultSubject(s)
Carcinoma, Neuroendocrine/diagnosis , Thyroid Gland/pathology , Thyroid Neoplasms/diagnosis , Age Factors , Aged , Biopsy , Carcinoma, Neuroendocrine/pathology , Carcinoma, Neuroendocrine/surgery , Humans , Male , Neck/diagnostic imaging , Neck/pathology , Necrosis , Positron-Emission Tomography , Thyroid Gland/surgery , Thyroid Neoplasms/pathology , Thyroid Neoplasms/surgeryABSTRACT
Juvenile psammomatoid ossifying fibroma is a rare benign fibro-osseous tumor of the gnathic and extragnathic craniofacial bones, particularly the periorbital, frontal and ethmoid bones. It is slowly progressive with aggressive local growth, invasion and destruction of the surrounding tissue, bone erosion and recurrence after surgical excision. It is distinguished from the other fibro-osseous lesions by its age of onset, clinical presentation and aggressive behavior.