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1.

Native American Genomic Diversity through Ancient DNA.

O'Connor, Timothy D.

Cell ; 175(5): 1173-1174, 2018 11 15.

Article in English | MEDLINE | ID: mdl-30445034

2.

Native American Genomic Diversity through Ancient DNA.

O'Connor, Timothy D.

Cell ; 176(1-2): 405-406, 2019 Jan 10.

Article in English | MEDLINE | ID: mdl-30633908

3.

A positively selected FBN1 missense variant reduces height in Peruvian individuals.

Asgari, Samira; Luo, Yang; Akbari, Ali; Belbin, Gillian M; Li, Xinyi; Harris, Daniel N; Selig, Martin; Bartell, Eric; Calderon, Roger; Slowikowski, Kamil; Contreras, Carmen; Yataco, Rosa; Galea, Jerome T; Jimenez, Judith; Coit, Julia M; Farroñay, Chandel; Nazarian, Rosalynn M; O'Connor, Timothy D; Dietz, Harry C; Hirschhorn, Joel N; Guio, Heinner; Lecca, Leonid; Kenny, Eimear E; Freeman, Esther E; Murray, Megan B; Raychaudhuri, Soumya.

Nature ; 582(7811): 234-239, 2020 06.

Article in English | MEDLINE | ID: mdl-32499652

4.

Racial, ethnic and country of origin disparities in aggressive endometrial cancer histologic subtypes.

Winkler, Stuart S; Tian, Chunqiao; Casablanca, Yovanni; Bateman, Nicholas W; Jokajtys, Suzanne; Kucera, Calen W; Tarney, Christopher M; Chan, John K; Richardson, Michael T; Kapp, Daniel S; Liao, Cheng-I; Hamilton, Chad A; Leath, Charles A; Reddy, Megan; Cote, Michele L; O'Connor, Timothy D; Jones, Nathaniel L; Rocconi, Rodney P; Powell, Matthew A; Farley, John; Shriver, Craig D; Conrads, Thomas P; Phippen, Neil T; Maxwell, G Larry; Darcy, Kathleen M.

Gynecol Oncol ; 184: 31-42, 2024 Jan 25.

Article in English | MEDLINE | ID: mdl-38277919

5.

Survival disparities in non-Hispanic Black and White cervical cancer patients vary by histology and are largely explained by modifiable factors.

Kucera, Calen W; Chappell, Nicole P; Tian, Chunqiao; Richardson, Michael T; Tarney, Christopher M; Hamilton, Chad A; Chan, John K; Kapp, Daniel S; Leath, Charles A; Casablanca, Yovanni; Rojas, Christine; Sitler, Collin A; Wenzel, Lari; Klopp, Ann; Jones, Nathaniel L; Rocconi, Rodney P; Farley, John H; O'Connor, Timothy D; Shriver, Craig D; Bateman, Nicholas W; Conrads, Thomas P; Phippen, Neil T; Maxwell, G Larry; Darcy, Kathleen M.

Gynecol Oncol ; 184: 224-235, 2024 Feb 09.

Article in English | MEDLINE | ID: mdl-38340648

6.

X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease.

Leal, Thiago P; Rao, Shilpa C; French-Kwawu, Jennifer N; Gouveia, Mateus H; Borda, Victor; Bandres-Ciga, Sara; Inca-Martinez, Miguel; Mason, Emily A; Horimoto, Andrea R V R; Loesch, Douglas P; Sarihan, Elif I; Cornejo-Olivas, Mario R; Torres, Luis E; Mazzetti-Soler, Pilar E; Cosentino, Carlos; Sarapura-Castro, Elison H; Rivera-Valdivia, Andrea; Medina, Angel C; Dieguez, Elena M; Raggio, Víctor E; Lescano, Andrés; Tumas, Vitor; Borges, Vanderci; Ferraz, Henrique B; Rieder, Carlos R; Schumacher Schuh, Artur; Santos-Lobato, Bruno L; Velez-Pardo, Carlos; Jimenez-Del-Rio, Marlene; Lopera, Francisco; Moreno, Sonia; Chana-Cuevas, Pedro; Fernandez, William; Arboleda, Gonzalo; Arboleda, Humberto; Arboleda Bustos, Carlos E; Yearout, Dora; Barbosa, Maira T; Cardoso, Francisco E C; Caramelli, Paulo; Cunningham, Mauro C Q; Maia, Débora P; Lima-Costa, Maria F; Tarazona-Santos, Eduardo; Zabetian, Cyrus P; Thornton, Timothy A; O'Connor, Timothy D; Mata, Ignacio F.

Mov Disord ; 38(9): 1625-1635, 2023 09.

Article in English | MEDLINE | ID: mdl-37469269

7.

Evolutionary history of modern Samoans.

Harris, Daniel N; Kessler, Michael D; Shetty, Amol C; Weeks, Daniel E; Minster, Ryan L; Browning, Sharon; Cochrane, Ethan E; Deka, Ranjan; Hawley, Nicola L; Reupena, Muagututi'a Sefuiva; Naseri, Take; McGarvey, Stephen T; O'Connor, Timothy D.

Proc Natl Acad Sci U S A ; 117(17): 9458-9465, 2020 04 28.

Article in English | MEDLINE | ID: mdl-32291332

8.

The genetic structure and adaptation of Andean highlanders and Amazonians are influenced by the interplay between geography and culture.

Borda, Víctor; Alvim, Isabela; Mendes, Marla; Silva-Carvalho, Carolina; Soares-Souza, Giordano B; Leal, Thiago P; Furlan, Vinicius; Scliar, Marilia O; Zamudio, Roxana; Zolini, Camila; Araújo, Gilderlanio S; Luizon, Marcelo R; Padilla, Carlos; Cáceres, Omar; Levano, Kelly; Sánchez, César; Trujillo, Omar; Flores-Villanueva, Pedro O; Dean, Michael; Fuselli, Silvia; Machado, Moara; Romero, Pedro E; Tassi, Francesca; Yeager, Meredith; O'Connor, Timothy D; Gilman, Robert H; Tarazona-Santos, Eduardo; Guio, Heinner.

Proc Natl Acad Sci U S A ; 117(51): 32557-32565, 2020 12 22.

Article in English | MEDLINE | ID: mdl-33277433

9.

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.

Kessler, Michael D; Loesch, Douglas P; Perry, James A; Heard-Costa, Nancy L; Taliun, Daniel; Cade, Brian E; Wang, Heming; Daya, Michelle; Ziniti, John; Datta, Soma; Celedón, Juan C; Soto-Quiros, Manuel E; Avila, Lydiana; Weiss, Scott T; Barnes, Kathleen; Redline, Susan S; Vasan, Ramachandran S; Johnson, Andrew D; Mathias, Rasika A; Hernandez, Ryan; Wilson, James G; Nickerson, Deborah A; Abecasis, Goncalo; Browning, Sharon R; Zöllner, Sebastian; O'Connell, Jeffrey R; Mitchell, Braxton D; O'Connor, Timothy D.

Proc Natl Acad Sci U S A ; 117(5): 2560-2569, 2020 02 04.

Article in English | MEDLINE | ID: mdl-31964835

10.

STRIDE: a command-line HMM-based identifier and sub-classifier of Plasmodium falciparum RIFIN and STEVOR variant surface antigen families.

Zhou, Albert E; Shah, Zalak V; Bradwell, Katie R; Munro, James B; Berry, Andrea A; Serre, David; Takala-Harrison, Shannon; O'Connor, Timothy D; Silva, Joana C; Travassos, Mark A.

BMC Bioinformatics ; 23(1): 15, 2022 Jan 06.

Article in English | MEDLINE | ID: mdl-34991452

11.

Characterizing the Genetic Architecture of Parkinson's Disease in Latinos.

Loesch, Douglas P; Horimoto, Andrea R V R; Heilbron, Karl; Sarihan, Elif I; Inca-Martinez, Miguel; Mason, Emily; Cornejo-Olivas, Mario; Torres, Luis; Mazzetti, Pilar; Cosentino, Carlos; Sarapura-Castro, Elison; Rivera-Valdivia, Andrea; Medina, Angel C; Dieguez, Elena; Raggio, Victor; Lescano, Andres; Tumas, Vitor; Borges, Vanderci; Ferraz, Henrique B; Rieder, Carlos R; Schumacher-Schuh, Artur; Santos-Lobato, Bruno L; Velez-Pardo, Carlos; Jimenez-Del-Rio, Marlene; Lopera, Francisco; Moreno, Sonia; Chana-Cuevas, Pedro; Fernandez, William; Arboleda, Gonzalo; Arboleda, Humberto; Arboleda-Bustos, Carlos E; Yearout, Dora; Zabetian, Cyrus P; Cannon, Paul; Thornton, Timothy A; O'Connor, Timothy D; Mata, Ignacio F.

Ann Neurol ; 90(3): 353-365, 2021 09.

Article in English | MEDLINE | ID: mdl-34227697

12.

Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes.

Scliar, Marilia O; Sant'Anna, Hanaisa P; Santolalla, Meddly L; Leal, Thiago P; Araújo, Nathalia M; Alvim, Isabela; Borda, Victor; Magalhães, Wagner C S; Gouveia, Mateus H; Lyra, Ricardo; Machado, Moara; Michelin, Lucas; Rodrigues, Maíra R; Araújo, Gilderlanio S; Kehdy, Fernanda S G; Zolini, Camila; Peixoto, Sérgio V; Luizon, Marcelo R; Lobo, Francisco; Naslavsky, Michel S; Yamamoto, Guilherme L; Duarte, Yeda A O; Hansen, Matthew E B; Norris, Shane A; Gilman, Robert H; Guio, Heinner; Hsing, Ann W; Mbulaiteye, Sam M; Mensah, James; Dutil, Julie; Yeager, Meredith; Yeboah, Edward; Tishkoff, Sarah A; Choudhury, Ananyo; Ramsay, Michele; Passos-Bueno, Maria Rita; Zatz, Mayana; O Connor, Timothy D; Pereira, Alexandre C; Barreto, Mauricio L; Lima-Costa, Maria Fernanda; Horta, Bernardo L; Tarazona-Santos, Eduardo.

Int J Obes (Lond) ; 45(5): 1017-1029, 2021 05.

Article in English | MEDLINE | ID: mdl-33633342

13.

Genome-Wide Analysis of Copy Number Variation in Latin American Parkinson's Disease Patients.

Sarihan, Elif Irem; Pérez-Palma, Eduardo; Niestroj, Lisa-Marie; Loesch, Douglas; Inca-Martinez, Miguel; Horimoto, Andrea R V R; Cornejo-Olivas, Mario; Torres, Luis; Mazzetti, Pilar; Cosentino, Carlos; Sarapura-Castro, Elison; Rivera-Valdivia, Andrea; Dieguez, Elena; Raggio, Victor; Lescano, Andres; Tumas, Vitor; Borges, Vanderci; Ferraz, Henrique B; Rieder, Carlos R; Schumacher-Schuh, Artur F; Santos-Lobato, Bruno L; Velez-Pardo, Carlos; Jimenez-Del-Rio, Marlene; Lopera, Francisco; Moreno, Sonia; Chana-Cuevas, Pedro; Fernandez, William; Arboleda, Gonzalo; Arboleda, Humberto; Arboleda-Bustos, Carlos E; Yearout, Dora; Zabetian, Cyrus P; Thornton, Timothy A; O'Connor, Timothy D; Lal, Dennis; Mata, Ignacio F.

Mov Disord ; 36(2): 434-441, 2021 02.

Article in English | MEDLINE | ID: mdl-33150996

14.

Inferring the "Primordial Immune Complex": Origins of MHC Class I and Antigen Receptors Revealed by Comparative Genomics.

Ohta, Yuko; Kasahara, Masanori; O'Connor, Timothy D; Flajnik, Martin F.

J Immunol ; 203(7): 1882-1896, 2019 10 01.

Article in English | MEDLINE | ID: mdl-31492741

15.

Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire.

Harris, Daniel N; Song, Wei; Shetty, Amol C; Levano, Kelly S; Cáceres, Omar; Padilla, Carlos; Borda, Víctor; Tarazona, David; Trujillo, Omar; Sanchez, Cesar; Kessler, Michael D; Galarza, Marco; Capristano, Silvia; Montejo, Harrison; Flores-Villanueva, Pedro O; Tarazona-Santos, Eduardo; O'Connor, Timothy D; Guio, Heinner.

Proc Natl Acad Sci U S A ; 115(28): E6526-E6535, 2018 07 10.

Article in English | MEDLINE | ID: mdl-29946025

16.

Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans.

Kehdy, Fernanda S G; Pita-Oliveira, Murilo; Scudeler, Mariana M; Torres-Loureiro, Sabrina; Zolini, Camila; Moreira, Rennan; Michelin, Lucas A; Alvim, Isabela; Silva-Carvalho, Carolina; Furlan, Vinicius C; Aquino, Marla M; Santolalla, Meddly L; Borda, Victor; Soares-Souza, Giordano B; Jaramillo-Valverde, Luis; Vasquez-Dominguez, Andres; Neira, Cesar Sanchez; Aguiar, Renato S; Verdugo, Ricardo A; O Connor, Timothy D; Guio, Heinner; Tarazona-Santos, Eduardo; Leal, Thiago P; Rodrigues-Soares, Fernanda.

Genet Mol Biol ; 44(1 Suppl 1): e20200484, 2021.

Article in English | MEDLINE | ID: mdl-34436507

17.

Detecting geospatial patterns of Plasmodium falciparum parasite migration in Cambodia using optimized estimated effective migration surfaces.

Li, Yao; Shetty, Amol C; Lon, Chanthap; Spring, Michele; Saunders, David L; Fukuda, Mark M; Hien, Tran Tinh; Pukrittayakamee, Sasithon; Fairhurst, Rick M; Dondorp, Arjen M; Plowe, Christopher V; O'Connor, Timothy D; Takala-Harrison, Shannon; Stewart, Kathleen.

Int J Health Geogr ; 19(1): 13, 2020 04 10.

Article in English | MEDLINE | ID: mdl-32276636

18.

Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences.

Kessler, Michael D; Bateman, Nicholas W; Conrads, Thomas P; Maxwell, George L; Dunning Hotopp, Julie C; O'Connor, Timothy D.

Cancer ; 125(12): 2076-2088, 2019 06 15.

Article in English | MEDLINE | ID: mdl-30865299

19.

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.

Fu, Wenqing; O'Connor, Timothy D; Jun, Goo; Kang, Hyun Min; Abecasis, Goncalo; Leal, Suzanne M; Gabriel, Stacey; Rieder, Mark J; Altshuler, David; Shendure, Jay; Nickerson, Deborah A; Bamshad, Michael J; Akey, Joshua M.

Nature ; 493(7431): 216-20, 2013 Jan 10.

Article in English | MEDLINE | ID: mdl-23201682

20.

Great ape genetic diversity and population history.

Prado-Martinez, Javier; Sudmant, Peter H; Kidd, Jeffrey M; Li, Heng; Kelley, Joanna L; Lorente-Galdos, Belen; Veeramah, Krishna R; Woerner, August E; O'Connor, Timothy D; Santpere, Gabriel; Cagan, Alexander; Theunert, Christoph; Casals, Ferran; Laayouni, Hafid; Munch, Kasper; Hobolth, Asger; Halager, Anders E; Malig, Maika; Hernandez-Rodriguez, Jessica; Hernando-Herraez, Irene; Prüfer, Kay; Pybus, Marc; Johnstone, Laurel; Lachmann, Michael; Alkan, Can; Twigg, Dorina; Petit, Natalia; Baker, Carl; Hormozdiari, Fereydoun; Fernandez-Callejo, Marcos; Dabad, Marc; Wilson, Michael L; Stevison, Laurie; Camprubí, Cristina; Carvalho, Tiago; Ruiz-Herrera, Aurora; Vives, Laura; Mele, Marta; Abello, Teresa; Kondova, Ivanela; Bontrop, Ronald E; Pusey, Anne; Lankester, Felix; Kiyang, John A; Bergl, Richard A; Lonsdorf, Elizabeth; Myers, Simon; Ventura, Mario; Gagneux, Pascal; Comas, David.

Nature ; 499(7459): 471-5, 2013 Jul 25.

Article in English | MEDLINE | ID: mdl-23823723

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Native American Genomic Diversity through Ancient DNA.

Native American Genomic Diversity through Ancient DNA.

A positively selected FBN1 missense variant reduces height in Peruvian individuals.

Racial, ethnic and country of origin disparities in aggressive endometrial cancer histologic subtypes.

Survival disparities in non-Hispanic Black and White cervical cancer patients vary by histology and are largely explained by modifiable factors.

X-Chromosome Association Study in Latin American Cohorts Identifies New Loci in Parkinson's Disease.

Evolutionary history of modern Samoans.

The genetic structure and adaptation of Andean highlanders and Amazonians are influenced by the interplay between geography and culture.

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.

STRIDE: a command-line HMM-based identifier and sub-classifier of Plasmodium falciparum RIFIN and STEVOR variant surface antigen families.

Characterizing the Genetic Architecture of Parkinson's Disease in Latinos.

Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes.

Genome-Wide Analysis of Copy Number Variation in Latin American Parkinson's Disease Patients.

Inferring the "Primordial Immune Complex": Origins of MHC Class I and Antigen Receptors Revealed by Comparative Genomics.

Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire.

Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans.

Detecting geospatial patterns of Plasmodium falciparum parasite migration in Cambodia using optimized estimated effective migration surfaces.

Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences.

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.

Great ape genetic diversity and population history.