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1.
J Aging Phys Act ; 25(2): 325-331, 2017 Apr.
Article in English | MEDLINE | ID: mdl-27620855

ABSTRACT

As a population, middle-aged and older adults are not meeting national guidelines for exercise. The purpose of this study was to describe factors associated with exercise adherence in an 8-month program offered as part of a research study testing the effects of exercise on cognitive performance for persons with a family history of Alzheimer's disease (AD). After completion of the program, participants provided open-ended responses indicating their reasons for adhering to the exercise program, and they completed the Motives for Physical Activities Measure-Revised. Results indicated that adherence was tied to an interest in contributing to our understanding of AD, the opportunity to join an exercise program, perceived exercise benefits, and social support. In addition, participants reported high levels of extrinsic (fitness-related) and intrinsic (interest/enjoyment) motivation. Other possible motivating factors which emerged from day-to-day observations in the program were identified. Findings suggest directions for exercise professionals with respect to exercise adherence.


Subject(s)
Alzheimer Disease/genetics , Exercise/psychology , Motivation , Patient Compliance , Aged , Alzheimer Disease/psychology , Female , Humans , Male , Middle Aged
2.
J Aging Phys Act ; 23(4): 559-68, 2015 Oct.
Article in English | MEDLINE | ID: mdl-25594264

ABSTRACT

Physical activity is predictive of better cognitive performance and lower risk of Alzheimer's disease (AD). The apolipoprotein E gene (APOE) is a susceptibility gene for AD with the e4 allele being associated with a greater risk of AD. Cross-sectional and prospective research shows that physical activity is predictive of better cognitive performance for those at greater genetic risk for AD. However, the moderating role of APOE on the effects of a physical activity intervention on cognitive performance has not been examined. The purpose of this manuscript is to justify the need for such research and to describe the design, methods, and recruitment tactics used in the conductance of a study designed to provide insight as to the extent to which cognitive benefits resulting from an 8-month physical activity program are differentiated by APOE e4 status. The effectiveness of the recruitment strategies and the feasibility of recruiting APOE e4 carriers are discussed.


Subject(s)
Aging/genetics , Aging/physiology , Alzheimer Disease/genetics , Alzheimer Disease/physiopathology , Apolipoprotein E4/genetics , Exercise Therapy , Motor Activity , Research Design , Aged , Demography , Female , Genetic Predisposition to Disease , Genotype , Humans , Male , Middle Aged , Neuropsychological Tests , North Carolina , Physical Fitness/physiology
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