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1.
Crystal Structure of Cucumene Synthase, a Terpenoid Cyclase That Generates a Linear Triquinane Sesquiterpene.
Biochemistry
; 57(44): 6326-6335, 2018 11 06.
Article
in English
| MEDLINE | ID: mdl-30346736
2.
Mechanistic Studies of the Protonation-Deprotonation Reactions for Type 1 and Type 2 Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase.
J Am Chem Soc
; 140(40): 12900-12908, 2018 10 10.
Article
in English
| MEDLINE | ID: mdl-30183274
3.
Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus.
Proc Natl Acad Sci U S A
; 112(18): 5661-6, 2015 May 05.
Article
in English
| MEDLINE | ID: mdl-25901324
4.
Structure-Function Studies of Artemisia tridentata Farnesyl Diphosphate Synthase and Chrysanthemyl Diphosphate Synthase by Site-Directed Mutagenesis and Morphogenesis.
J Am Chem Soc
; 139(41): 14556-14567, 2017 10 18.
Article
in English
| MEDLINE | ID: mdl-28926242
5.
Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials.
Chembiochem
; 18(21): 2137-2144, 2017 11 02.
Article
in English
| MEDLINE | ID: mdl-28862365
6.
Defining the Product Chemical Space of Monoterpenoid Synthases.
PLoS Comput Biol
; 12(8): e1005053, 2016 08.
Article
in English
| MEDLINE | ID: mdl-27517297
7.
Kinetic and Binding Studies of Streptococcus pneumoniae Type 2 Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase.
Biochemistry
; 55(15): 2260-8, 2016 Apr 19.
Article
in English
| MEDLINE | ID: mdl-27003727
8.
Construction of Functional Monomeric Type 2 Isopentenyl Diphosphate:Dimethylallyl Diphosphate Isomerase.
Biochemistry
; 55(30): 4229-38, 2016 08 02.
Article
in English
| MEDLINE | ID: mdl-27379573
9.
Site-Selective Synthesis of (15)N- and (13)C-Enriched Flavin Mononucleotide Coenzyme Isotopologues.
J Org Chem
; 81(12): 5087-92, 2016 06 17.
Article
in English
| MEDLINE | ID: mdl-27176708
10.
Synthesis and Enzymatic Studies of Isoprenoid Thiolo Bisubstrate Analogues.
J Org Chem
; 81(12): 5093-100, 2016 06 17.
Article
in English
| MEDLINE | ID: mdl-27137644
11.
Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc Natl Acad Sci U S A
; 110(13): E1196-202, 2013 Mar 26.
Article
in English
| MEDLINE | ID: mdl-23493556
12.
Predicting the functions and specificity of triterpenoid synthases: a mechanism-based multi-intermediate docking approach.
PLoS Comput Biol
; 10(10): e1003874, 2014 Oct.
Article
in English
| MEDLINE | ID: mdl-25299649
13.
Synthesis and enzymatic studies of bisubstrate analogues for farnesyl diphosphate synthase.
J Org Chem
; 80(8): 3902-13, 2015 Apr 17.
Article
in English
| MEDLINE | ID: mdl-25734506
14.
Isoprenoid Biosynthesis in Pathogenic Bacteria: Nuclear Resonance Vibrational Spectroscopy Provides Insight into the Unusual [4Fe-4S] Cluster of the E.â coli LytB/IspH Protein.
Angew Chem Int Ed Engl
; 54(43): 12584-7, 2015 Oct 19.
Article
in English
| MEDLINE | ID: mdl-26118554
15.
Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase from Streptococcus pneumoniae.
Chembiochem
; 15(10): 1452-8, 2014 Jul 07.
Article
in English
| MEDLINE | ID: mdl-24910111
16.
Regio- and chemoselective immobilization of proteins on gold surfaces.
Bioconjug Chem
; 25(2): 269-75, 2014 Feb 19.
Article
in English
| MEDLINE | ID: mdl-24437976
17.
Sandwich antibody arrays using recombinant antibody-binding protein L.
Langmuir
; 30(22): 6629-35, 2014 Jun 10.
Article
in English
| MEDLINE | ID: mdl-24841983
18.
δ-Deuterium isotope effects as probes for transition-state structures of isoprenoid substrates.
J Org Chem
; 79(8): 3572-80, 2014 Apr 18.
Article
in English
| MEDLINE | ID: mdl-24665882
19.
Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens.
J Org Chem
; 79(19): 9170-8, 2014 Oct 03.
Article
in English
| MEDLINE | ID: mdl-25184438
20.
Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors.
Proc Natl Acad Sci U S A
; 108(51): 20461-6, 2011 Dec 20.
Article
in English
| MEDLINE | ID: mdl-22158896