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J Trop Pediatr ; 60(1): 40-6, 2014 Feb.
Article in English | MEDLINE | ID: mdl-23963460

ABSTRACT

OBJECTIVE: Assess drinking water fortification with iron and/or ascorbic acid as a strategy to control iron-deficiency anemia and iron deficiency. METHODS: Randomized blind clinical study, fortifying drinking water to 153 pre-school children during 3 months, with iron and ascorbic acid (A), ascorbic acid (B) or plain water (C). Hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin were measured. RESULTS: Within the groups, Hb raised in all three groups, MCV in A and B and ferritin in A. The difference between time points 0 and 1 was significant between A and B for Hb, when A and B were compared with C for MCV and when A was compared with either B or C for ferritin. CONCLUSIONS: Water fortification is efficient in controlling iron deficiency and anemia. Iron stores' recovery depends on a more effective offer of iron. Water fortification must be preceded by a careful assessment of the previous nutritional status.


Subject(s)
Anemia, Iron-Deficiency/prevention & control , Ascorbic Acid/administration & dosage , Child Day Care Centers , Drinking Water , Food, Fortified , Hemoglobins/analysis , Iron/administration & dosage , Anemia, Iron-Deficiency/epidemiology , Brazil/epidemiology , Child, Preschool , Double-Blind Method , Female , Hemoglobins/drug effects , Humans , Iron Deficiencies , Male , Nutrition Assessment , Nutritional Status , Prevalence , Treatment Outcome , Vitamins/administration & dosage
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