Search details
1.
Effective growth hormone replacement with once-weekly somapacitan in Japanese children with growth hormone deficiency: Results from REAL4, a phase 3 clinical trial.
Clin Endocrinol (Oxf)
; 100(4): 389-398, 2024 04.
Article
in English
| MEDLINE | ID: mdl-38368603
2.
Weekly somapacitan had no adverse effects on glucose metabolism in adults with growth hormone deficiency.
Pituitary
; 26(1): 57-72, 2023 Feb.
Article
in English
| MEDLINE | ID: mdl-36380045
3.
Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial.
Clin Endocrinol (Oxf)
; 87(4): 350-358, 2017 Oct.
Article
in English
| MEDLINE | ID: mdl-28656605
4.
Understanding burden of illness for child growth hormone deficiency.
Qual Life Res
; 26(7): 1673-1686, 2017 07.
Article
in English
| MEDLINE | ID: mdl-28247315
5.
Psychometric Validation of the Growth Hormone Deficiency-Child Treatment Burden Measure (GHD-CTB) and the Growth Hormone Deficiency-Parent Treatment Burden Measure (GHD-PTB).
Pharmacoecon Open
; 7(1): 121-138, 2023 Jan.
Article
in English
| MEDLINE | ID: mdl-36255609
6.
Effective GH Replacement With Somapacitan in Children With GHD: REAL4 2-year Results and After Switch From Daily GH.
J Clin Endocrinol Metab
; 108(12): 3090-3099, 2023 Nov 17.
Article
in English
| MEDLINE | ID: mdl-37406251
7.
Dose-exposure-IGF-I response of once-weekly somapacitan in adults with GH deficiency.
Eur J Endocrinol
; 187(1): 27-38, 2022 May 16.
Article
in English
| MEDLINE | ID: mdl-35521713
8.
Weekly Somapacitan is Effective and Well Tolerated in Children With GH Deficiency: The Randomized Phase 3 REAL4 Trial.
J Clin Endocrinol Metab
; 107(12): 3378-3388, 2022 11 25.
Article
in English
| MEDLINE | ID: mdl-36062966
9.
Absorption, metabolism and excretion of once-weekly somapacitan, a long-acting growth hormone derivative, after single subcutaneous dosing in human subjects.
Eur J Pharm Sci
; 167: 106030, 2021 Dec 01.
Article
in English
| MEDLINE | ID: mdl-34601071
10.
Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis.
J Physiol
; 588(Pt 2): 341-51, 2010 Jan 15.
Article
in English
| MEDLINE | ID: mdl-19933753
11.
Multiple doses of pegylated long-acting growth hormone are well tolerated in healthy male volunteers and possess a potential once-weekly treatment profile.
Clin Endocrinol (Oxf)
; 73(6): 769-76, 2010 Dec.
Article
in English
| MEDLINE | ID: mdl-20718773
12.
Pharmacokinetics and Pharmacodynamics of Once-Weekly Somapacitan in Children and Adults: Supporting Dosing Rationales with a Model-Based Analysis of Three Phase I Trials.
Clin Pharmacokinet
; 58(1): 63-75, 2019 01.
Article
in English
| MEDLINE | ID: mdl-29671202
13.
Assessing the Impact of Growth Hormone Deficiency (GHD) in Adults: Interpreting Change of the Treatment-Related Impact Measure-Adult Growth Hormone Deficiency (TRIM-AGHD).
Pharmacoecon Open
; 3(1): 71-80, 2019 Mar.
Article
in English
| MEDLINE | ID: mdl-29797004
14.
Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial.
Eur J Endocrinol
; 178(5): 491-499, 2018 May.
Article
in English
| MEDLINE | ID: mdl-29500310
15.
Response to Letter to the Editor From Chatelain et al: "Weekly Somapacitan Is Effective and Well Tolerated in Children With GH Deficiency: The Randomized Phase 3 REAL4 Trial".
J Clin Endocrinol Metab
; 108(8): e647-e648, 2023 07 14.
Article
in English
| MEDLINE | ID: mdl-36869702
16.
Effects of growth hormone in patients with tibial fracture: a randomised, double-blind, placebo-controlled clinical trial.
Eur J Endocrinol
; 156(3): 341-51, 2007 Mar.
Article
in English
| MEDLINE | ID: mdl-17322494
17.
Understanding Treatment Burden for Children Treated for Growth Hormone Deficiency.
Patient
; 10(5): 653-666, 2017 10.
Article
in English
| MEDLINE | ID: mdl-28386679
18.
Effects of short-term caloric restriction on circulating free IGF-I, acid-labile subunit, IGF-binding proteins (IGFBPs)-1-4, and IGFBPs-1-3 protease activity in obese subjects.
Eur J Endocrinol
; 155(4): 575-81, 2006 Oct.
Article
in English
| MEDLINE | ID: mdl-16990657
19.
Reversible Albumin-Binding GH Possesses a Potential Once-Weekly Treatment Profile in Adult Growth Hormone Deficiency.
J Clin Endocrinol Metab
; 101(3): 988-98, 2016 Mar.
Article
in English
| MEDLINE | ID: mdl-26727076
20.
Dose dependency of the pharmacokinetics and acute lipolytic actions of growth hormone.
J Clin Endocrinol Metab
; 87(10): 4691-8, 2002 Oct.
Article
in English
| MEDLINE | ID: mdl-12364460