Search details
1.
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model.
Hum Mol Genet
; 2024 May 22.
Article
in English
| MEDLINE | ID: mdl-38776957
2.
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
Proc Natl Acad Sci U S A
; 114(52): E11293-E11302, 2017 12 26.
Article
in English
| MEDLINE | ID: mdl-29229845
3.
Metabolite mapping reveals severe widespread perturbation of multiple metabolic processes in Huntington's disease human brain.
Biochim Biophys Acta
; 1862(9): 1650-62, 2016 09.
Article
in English
| MEDLINE | ID: mdl-27267344
4.
Identification of elevated urea as a severe, ubiquitous metabolic defect in the brain of patients with Huntington's disease.
Biochem Biophys Res Commun
; 468(1-2): 161-6, 2015.
Article
in English
| MEDLINE | ID: mdl-26522227
5.
Somatic CAG Repeat Stability in a Transgenic Sheep Model of Huntington's Disease.
J Huntingtons Dis
; 13(1): 33-40, 2024.
Article
in English
| MEDLINE | ID: mdl-38393920
6.
Levels of Synaptic Proteins in Brain and Neurofilament Light Chain in Cerebrospinal Fluid and Plasma of OVT73 Huntington's Disease Sheep Support a Prodromal Disease State.
J Huntingtons Dis
; 12(3): 201-213, 2023.
Article
in English
| MEDLINE | ID: mdl-37661892
7.
An ovine transgenic Huntington's disease model.
Hum Mol Genet
; 19(10): 1873-82, 2010 May 15.
Article
in English
| MEDLINE | ID: mdl-20154343
8.
A Multi-Omic Huntington's Disease Transgenic Sheep-Model Database for Investigating Disease Pathogenesis.
J Huntingtons Dis
; 10(4): 423-434, 2021.
Article
in English
| MEDLINE | ID: mdl-34420978
9.
Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease.
Metabolites
; 9(6)2019 Jun 11.
Article
in English
| MEDLINE | ID: mdl-31212603
10.
Chemical neuroanatomy of the substantia nigra in the ovine brain.
J Chem Neuroanat
; 97: 43-56, 2019 04.
Article
in English
| MEDLINE | ID: mdl-30664938
11.
Modelling brain dopamine-serotonin vesicular transport disease in Caenorhabditis elegans.
Dis Model Mech
; 11(11)2018 11 09.
Article
in English
| MEDLINE | ID: mdl-30266839
12.
Artificial miRNAs Reduce Human Mutant Huntingtin Throughout the Striatum in a Transgenic Sheep Model of Huntington's Disease.
Hum Gene Ther
; 29(6): 663-673, 2018 06.
Article
in English
| MEDLINE | ID: mdl-29207890
13.
Alzheimer's disease markers in the aged sheep (Ovis aries).
Neurobiol Aging
; 58: 112-119, 2017 10.
Article
in English
| MEDLINE | ID: mdl-28728117
14.
Potential molecular consequences of transgene integration: The R6/2 mouse example.
Sci Rep
; 7: 41120, 2017 01 25.
Article
in English
| MEDLINE | ID: mdl-28120936
15.
Comparison of Huntington's disease CAG Repeat Length Stability in Human Motor Cortex and Cingulate Gyrus.
J Huntingtons Dis
; 5(3): 297-301, 2016 10 01.
Article
in English
| MEDLINE | ID: mdl-27716680
16.
Metabolic disruption identified in the Huntington's disease transgenic sheep model.
Sci Rep
; 6: 20681, 2016 Feb 11.
Article
in English
| MEDLINE | ID: mdl-26864449
17.
Rapid RNA analysis of individual Caenorhabditis elegans.
MethodsX
; 2: 59-63, 2015.
Article
in English
| MEDLINE | ID: mdl-26150972
18.
Insoluble TATA-binding protein accumulation in Huntington's disease cortex.
Brain Res Mol Brain Res
; 109(1-2): 1-10, 2002 Dec 30.
Article
in English
| MEDLINE | ID: mdl-12531510
19.
TBP, a polyglutamine tract containing protein, accumulates in Alzheimer's disease.
Brain Res Mol Brain Res
; 125(1-2): 120-8, 2004 Jun 18.
Article
in English
| MEDLINE | ID: mdl-15193429
20.
Further molecular characterisation of the OVT73 transgenic sheep model of Huntington's disease identifies cortical aggregates.
J Huntingtons Dis
; 2(3): 279-95, 2013.
Article
in English
| MEDLINE | ID: mdl-25062676