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1.

Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway.

Grusanovic, Srdjan; Danek, Petr; Kuzmina, Maria; Adamcova, Miroslava K; Burocziova, Monika; Mikyskova, Romana; Vanickova, Karolina; Kosanovic, Sladjana; Pokorna, Jana; Reinis, Milan; Brdicka, Tomas; Alberich-Jorda, Meritxell.

EMBO Rep ; 24(1): e54729, 2023 01 09.

Article in English | MEDLINE | ID: mdl-36341527

2.

PEGylated Molybdenum-Iodine Nanocluster as a Promising Radiodynamic Agent against Prostatic Adenocarcinoma.

Pribyl, Tomás; Rumlová, Michaela; Mikysková, Romana; Reinis, Milan; Kana, Antonín; Skoch, Karel; Zelenka, Jaroslav; Kirakci, Kaplan; Ruml, Tomás; Lang, Kamil.

Inorg Chem ; 63(9): 4419-4428, 2024 Mar 04.

Article in English | MEDLINE | ID: mdl-38364266

3.

Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition.

Oleksak, Patrik; Psotka, Miroslav; Vancurova, Marketa; Sapega, Olena; Bieblova, Jana; Reinis, Milan; Rysanek, David; Mikyskova, Romana; Chalupova, Katarina; Malinak, David; Svobodova, Jana; Andrys, Rudolf; Rehulkova, Helena; Skopek, Vojtech; Ngoc Lam, Pham; Bartek, Jiri; Hodny, Zdenek; Musilek, Kamil.

J Enzyme Inhib Med Chem ; 36(1): 410-424, 2021 Dec.

Article in English | MEDLINE | ID: mdl-33440995

4.

Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients.

Truxova, Iva; Kasikova, Lenka; Salek, Cyril; Hensler, Michal; Lysak, Daniel; Holicek, Peter; Bilkova, Pavla; Holubova, Monika; Chen, Xiufen; Mikyskova, Romana; Reinis, Milan; Kovar, Marek; Tomalova, Barbora; Kline, Justin P; Galluzzi, Lorenzo; Spisek, Radek; Fucikova, Jitka.

Haematologica ; 105(7): 1868-1878, 2020 07.

Article in English | MEDLINE | ID: mdl-31582537

5.

STAT3 inhibitor Stattic and its analogues inhibit STAT3 phosphorylation and modulate cytokine secretion in senescent tumour cells.

Mikyskova, Romana; Sapega, Olena; Psotka, Miroslav; Novotny, Ondrej; Hodny, Zdenek; Balintova, Sona; Malinak, David; Svobodova, Jana; Andrys, Rudolf; Rysanek, David; Musilek, Kamil; Reinis, Milan.

Mol Med Rep ; 27(4)2023 04.

Article in English | MEDLINE | ID: mdl-36825563

6.

Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients.

Holicek, Peter; Truxova, Iva; Rakova, Jana; Salek, Cyril; Hensler, Michal; Kovar, Marek; Reinis, Milan; Mikyskova, Romana; Pasulka, Josef; Vosahlikova, Sarka; Remesova, Hana; Valentova, Iva; Lysak, Daniel; Holubova, Monika; Kaspar, Petr; Prochazka, Jan; Kasikova, Lenka; Spisek, Radek; Galluzzi, Lorenzo; Fucikova, Jitka.

Cell Death Dis ; 14(3): 209, 2023 03 24.

Article in English | MEDLINE | ID: mdl-36964168

7.

Avenue to X-ray-induced photodynamic therapy of prostatic carcinoma with octahedral molybdenum cluster nanoparticles.

Koncosová, Martina; Rumlová, Michaela; Mikysková, Romana; Reinis, Milan; Zelenka, Jaroslav; Ruml, Tomás; Kirakci, Kaplan; Lang, Kamil.

J Mater Chem B ; 10(17): 3303-3310, 2022 05 04.

Article in English | MEDLINE | ID: mdl-35380154

8.

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics.

Chrienova, Zofia; Rysanek, David; Oleksak, Patrik; Stary, Dorota; Bajda, Marek; Reinis, Milan; Mikyskova, Romana; Novotny, Ondrej; Andrys, Rudolf; Skarka, Adam; Vasicova, Pavla; Novak, Josef; Valis, Martin; Kuca, Kamil; Hodny, Zdenek; Nepovimova, Eugenie.

Front Aging Neurosci ; 14: 1048260, 2022.

Article in English | MEDLINE | ID: mdl-36561137

9.

Therapy for minimal residual tumor disease: beta-galactosylceramide inhibits the growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy.

Símová, Jana; Indrová, Marie; Bieblová, Jana; Mikysková, Romana; Bubeník, Jan; Reinis, Milan.

Int J Cancer ; 126(12): 2997-3004, 2010 Jun 15.

Article in English | MEDLINE | ID: mdl-19739073

10.

Immunotherapy of MHC class I-deficient tumors.

Reinis, Milan.

Future Oncol ; 6(10): 1577-89, 2010 Oct.

Article in English | MEDLINE | ID: mdl-21062157

11.

HPV 16-associated tumours: IL-12 can repair the absence of cytotoxic and proliferative responses of tumour infiltrating cells after chemotherapy.

Indrová, Marie; Bieblová, Jana; Rossowska, Joana; Kuropka, Piotr; Pajtasz-Piasecka, Elzbieta; Bubeník, Jan; Reinis, Milan.

Int J Oncol ; 34(1): 173-9, 2009 Jan.

Article in English | MEDLINE | ID: mdl-19082488

12.

Methods for viral RNA isolation and PCR amplification for sequencing of near full-length HIV-1 genomes.

Kemal, Kimdar Sherefa; Reinis, Milan; Weiser, Barbara; Burger, Harold.

Methods Mol Biol ; 485: 3-14, 2009.

Article in English | MEDLINE | ID: mdl-19020814

13.

Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours.

Manning, Jasper; Indrova, Marie; Lubyova, Barbora; Pribylova, Hana; Bieblova, Jana; Hejnar, Jiri; Simova, Jana; Jandlova, Tana; Bubenik, Jan; Reinis, Milan.

Immunology ; 123(2): 218-27, 2008 Feb.

Article in English | MEDLINE | ID: mdl-17725605

14.

IL-12 immunotherapy of minimal residual disease in murine models of HPV16-associated tumours: induction of immune responses, cytokine production and kinetics of immune cell subsets.

Indrová, Marie; Bieblová, Jana; Bubeník, Jan; Reinis, Milan.

Int J Oncol ; 32(2): 499-507, 2008 Feb.

Article in English | MEDLINE | ID: mdl-18202774

15.

BiovaxID, a personalized therapeutic vaccine against B-cell lymphomas.

Reinis, Milan.

Curr Opin Mol Ther ; 10(5): 526-34, 2008 Oct.

Article in English | MEDLINE | ID: mdl-18830928

16.

A study of HIV-1 genetic diversity in the Czech Republic: 1986-2007.

Linka, Marek; Brucková, Marie; Malý, Marek; Vandasová, Jana; Stanková, Marie; Reinis, Milan.

Cent Eur J Public Health ; 16(4): 175-7, 2008 Dec.

Article in English | MEDLINE | ID: mdl-19256285

17.

Distinct phenotypes and 'bystander' effects of senescent tumour cells induced by docetaxel or immunomodulatory cytokines.

Sapega, Olena; Mikysková, Romana; Bieblová, Jana; Mrázková, Blanka; Hodný, Zdenek; Reinis, Milan.

Int J Oncol ; 53(5): 1997-2009, 2018 Nov.

Article in English | MEDLINE | ID: mdl-30226595

18.

Biological safety and tissue distribution of (16-mercaptohexadecyl)trimethylammonium bromide-modified cationic gold nanorods.

Zarska, Monika; Sramek, Michal; Novotny, Filip; Havel, Filip; Babelova, Andrea; Mrazkova, Blanka; Benada, Oldrich; Reinis, Milan; Stepanek, Ivan; Musilek, Kamil; Bartek, Jiri; Ursinyova, Monika; Novak, Ondrej; Dzijak, Rastislav; Kuca, Kamil; Proska, Jan; Hodny, Zdenek.

Biomaterials ; 154: 275-290, 2018 Feb.

Article in English | MEDLINE | ID: mdl-29149721

19.

Genomic analysis of HIV type 1 strains derived from a mother and child pair of long-term nonprogressors.

Reinis, Milan; Weiser, Barbara; Kuiken, Carla; Dong, Tao; Lang, Dorothy; Nachman, Sharon; Zhang, Yonghong; Rowland-Jones, Sarah; Burger, Harold.

AIDS Res Hum Retroviruses ; 23(2): 309-15, 2007 Feb.

Article in English | MEDLINE | ID: mdl-17331038

20.

CpG oligodeoxynucleotides are effective in therapy of minimal residual tumour disease after chemotherapy or surgery in a murine model of MHC class I-deficient, HPV16-associated tumours.

Reinis, Milan; Símová, Jana; Indrová, Marie; Bieblová, Jana; Bubeník, Jan.

Int J Oncol ; 30(5): 1247-51, 2007 May.

Article in English | MEDLINE | ID: mdl-17390028

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