Search details
1.
The amyloid cascade hypothesis: an updated critical review.
Brain
; 146(10): 3969-3990, 2023 10 03.
Article
in English
| MEDLINE | ID: mdl-37183523
2.
PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival.
Mol Psychiatry
; 26(6): 1996-2012, 2021 06.
Article
in English
| MEDLINE | ID: mdl-32541930
3.
What Do Recent Clinical Trials Teach Us About the Etiology of AD.
Adv Exp Med Biol
; 1195: 167, 2020.
Article
in English
| MEDLINE | ID: mdl-32468473
4.
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.
Hum Mol Genet
; 26(10): 1942-1951, 2017 05 15.
Article
in English
| MEDLINE | ID: mdl-28335009
5.
Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15.
FASEB J
; 32(1): 243-253, 2018 01.
Article
in English
| MEDLINE | ID: mdl-28855274
6.
The product of the γ-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis.
Cell Mol Life Sci
; 75(15): 2813-2826, 2018 08.
Article
in English
| MEDLINE | ID: mdl-29428965
7.
Phospholipid dysregulation contributes to ApoE4-associated cognitive deficits in Alzheimer's disease pathogenesis.
Proc Natl Acad Sci U S A
; 112(38): 11965-70, 2015 Sep 22.
Article
in English
| MEDLINE | ID: mdl-26372964
8.
Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.
FASEB J
; 29(9): 3702-12, 2015 Sep.
Article
in English
| MEDLINE | ID: mdl-25985800
9.
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.
Hum Mol Genet
; 2018 Jun 29.
Article
in English
| MEDLINE | ID: mdl-29982455
10.
Presenilin-1/γ-secretase controls glutamate release, tyrosine phosphorylation, and surface expression of N-methyl-D-aspartate receptor (NMDAR) subunit GluN2B.
J Biol Chem
; 288(42): 30495-30501, 2013 Oct 18.
Article
in English
| MEDLINE | ID: mdl-24025330
11.
Reduction of synaptojanin 1 accelerates Aß clearance and attenuates cognitive deterioration in an Alzheimer mouse model.
J Biol Chem
; 288(44): 32050-63, 2013 Nov 01.
Article
in English
| MEDLINE | ID: mdl-24052255
12.
Cell signaling abnormalities may drive neurodegeneration in familial Alzheimer disease.
Neurochem Res
; 39(3): 570-5, 2014.
Article
in English
| MEDLINE | ID: mdl-23436150
13.
Allelic interference: a mechanism for trans-dominant transmission of loss of function in the neurodegeneration of familial Alzheimer's disease.
Neurodegener Dis
; 13(2-3): 126-30, 2014.
Article
in English
| MEDLINE | ID: mdl-24081144
14.
Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village.
Ageing Res Rev
; 93: 102173, 2024 Jan.
Article
in English
| MEDLINE | ID: mdl-38104639
15.
The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes.
J Alzheimers Dis
; 94(2): 497-507, 2023.
Article
in English
| MEDLINE | ID: mdl-37334596
16.
Passive Alzheimer's immunotherapy: A promising or uncertain option?
Ageing Res Rev
; 90: 101996, 2023 09.
Article
in English
| MEDLINE | ID: mdl-37414156
17.
Inhibitors of γ-secretase stabilize the complex and differentially affect processing of amyloid precursor protein and other substrates.
FASEB J
; 25(9): 2937-46, 2011 Sep.
Article
in English
| MEDLINE | ID: mdl-21597003
18.
Presenilin1/gamma-secretase promotes the EphB2-induced phosphorylation of ephrinB2 by regulating phosphoprotein associated with glycosphingolipid-enriched microdomains/Csk binding protein.
FASEB J
; 25(10): 3594-604, 2011 Oct.
Article
in English
| MEDLINE | ID: mdl-21746865
19.
Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling.
Nat Cell Biol
; 24(12): 1739-1753, 2022 12.
Article
in English
| MEDLINE | ID: mdl-36456828
20.
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis.
J Neurosci
; 30(45): 14946-54, 2010 Nov 10.
Article
in English
| MEDLINE | ID: mdl-21068297