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1.

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition.

Modic, Miha; Grosch, Markus; Rot, Gregor; Schirge, Silvia; Lepko, Tjasa; Yamazaki, Tomohiro; Lee, Flora C Y; Rusha, Ejona; Shaposhnikov, Dmitry; Palo, Michael; Merl-Pham, Juliane; Cacchiarelli, Davide; Rogelj, Boris; Hauck, Stefanie M; von Mering, Christian; Meissner, Alexander; Lickert, Heiko; Hirose, Tetsuro; Ule, Jernej; Drukker, Micha.

Mol Cell ; 74(5): 951-965.e13, 2019 06 06.

Article in English | MEDLINE | ID: mdl-31047794

2.

Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.

Motaln, Helena; Cercek, Ursa; Yamoah, Alfred; Tripathi, Priyanka; Aronica, Eleonora; Goswami, Anand; Rogelj, Boris.

Brain ; 146(10): 4088-4104, 2023 10 03.

Article in English | MEDLINE | ID: mdl-37071594

3.

Cytoplasmic TDP-43 is involved in cell fate during stress recovery.

Lee, Youn-Bok; Scotter, Emma L; Lee, Do-Young; Troakes, Claire; Mitchell, Jacqueline; Rogelj, Boris; Gallo, Jean-Marc; Shaw, Christopher E.

Hum Mol Genet ; 31(2): 166-175, 2021 12 27.

Article in English | MEDLINE | ID: mdl-34378050

4.

SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.

Malnar, Mirjana; Rogelj, Boris.

J Cell Sci ; 134(4)2021 02 19.

Article in English | MEDLINE | ID: mdl-33495278

5.

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.

Bozic, Janja; Motaln, Helena; Janez, Anja Pucer; Markic, Lara; Tripathi, Priyanka; Yamoah, Alfred; Aronica, Eleonora; Lee, Youn-Bok; Heilig, Raphael; Fischer, Roman; Thompson, Andrew J; Goswami, Anand; Rogelj, Boris.

Brain ; 145(2): 684-699, 2022 04 18.

Article in English | MEDLINE | ID: mdl-34534264

6.

Karyopherin abnormalities in neurodegenerative proteinopathies.

Pasha, Terouz; Zatorska, Anna; Sharipov, Daulet; Rogelj, Boris; Hortobágyi, Tibor; Hirth, Frank.

Brain ; 144(10): 2915-2932, 2021 11 29.

Article in English | MEDLINE | ID: mdl-34019093

7.

Functional diversity of small nucleolar RNAs.

Bratkovic, Tomaz; Bozic, Janja; Rogelj, Boris.

Nucleic Acids Res ; 48(4): 1627-1651, 2020 02 28.

Article in English | MEDLINE | ID: mdl-31828325

8.

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies.

Bajc Cesnik, Ana; Darovic, Simona; Prpar Mihevc, Sonja; Stalekar, Maja; Malnar, Mirjana; Motaln, Helena; Lee, Youn-Bok; Mazej, Julija; Pohleven, Jure; Grosch, Markus; Modic, Miha; Fonovic, Marko; Turk, Boris; Drukker, Micha; Shaw, Christopher E; Rogelj, Boris.

J Cell Sci ; 132(5)2019 03 07.

Article in English | MEDLINE | ID: mdl-30745340

9.

Intracellular Responses Triggered by Cold Atmospheric Plasma and Plasma-Activated Media in Cancer Cells.

Motaln, Helena; Recek, Nina; Rogelj, Boris.

Molecules ; 26(5)2021 Mar 02.

Article in English | MEDLINE | ID: mdl-33801451

10.

Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model.

Donadon, Irving; Pinotti, Mirko; Rajkowska, Katarzyna; Pianigiani, Giulia; Barbon, Elena; Morini, Elisabetta; Motaln, Helena; Rogelj, Boris; Mingozzi, Federico; Slaugenhaupt, Susan A; Pagani, Franco.

Hum Mol Genet ; 27(14): 2466-2476, 2018 07 15.

Article in English | MEDLINE | ID: mdl-29701768

11.

Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD.

Bozic, Tim; Zalar, Matja; Rogelj, Boris; Plavec, Janez; Sket, Primoz.

Molecules ; 25(3)2020 Jan 25.

Article in English | MEDLINE | ID: mdl-31991801

12.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

Lee, Youn-Bok; Baskaran, Pranetha; Gomez-Deza, Jorge; Chen, Han-Jou; Nishimura, Agnes L; Smith, Bradley N; Troakes, Claire; Adachi, Yoshitsugu; Stepto, Alan; Petrucelli, Leonard; Gallo, Jean-Marc; Hirth, Frank; Rogelj, Boris; Guthrie, Sarah; Shaw, Christopher E.

Hum Mol Genet ; 26(24): 4765-4777, 2017 12 15.

Article in English | MEDLINE | ID: mdl-28973350

13.

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.

Solomon, Daniel A; Stepto, Alan; Au, Wing Hei; Adachi, Yoshitsugu; Diaper, Danielle C; Hall, Rachel; Rekhi, Anjeet; Boudi, Adel; Tziortzouda, Paraskevi; Lee, Youn-Bok; Smith, Bradley; Bridi, Jessika C; Spinelli, Greta; Dearlove, Jonah; Humphrey, Dickon M; Gallo, Jean-Marc; Troakes, Claire; Fanto, Manolis; Soller, Matthias; Rogelj, Boris; Parsons, Richard B; Shaw, Christopher E; Hortobágyi, Tibor; Hirth, Frank.

Brain ; 141(10): 2908-2924, 2018 10 01.

Article in English | MEDLINE | ID: mdl-30239641

14.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

Lee, Youn-Bok; Baskaran, Pranetha; Gomez-Deza, Jorge; Chen, Han-Jou; Nishimura, Agnes L; Smith, Bradley N; Troakes, Claire; Adachi, Yoshitsugu; Stepto, Alan; Petrucelli, Leonard; Gallo, Jean-Marc; Hirth, Frank; Rogelj, Boris; Guthrie, Sarah; Shaw, Christopher E.

Hum Mol Genet ; 30(3-4): 318-320, 2021 Apr 26.

Article in English | MEDLINE | ID: mdl-32888026

15.

Nuclear trafficking in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

Prpar Mihevc, Sonja; Darovic, Simona; Kovanda, Anja; Bajc Cesnik, Ana; Zupunski, Vera; Rogelj, Boris.

Brain ; 140(1): 13-26, 2017 01.

Article in English | MEDLINE | ID: mdl-27497493

16.

Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import.

Darovic, Simona; Prpar Mihevc, Sonja; Zupunski, Vera; Guncar, Gregor; Stalekar, Maja; Lee, Youn-Bok; Shaw, Christopher E; Rogelj, Boris.

J Cell Sci ; 128(22): 4151-9, 2015 Nov 15.

Article in English | MEDLINE | ID: mdl-26403203

17.

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species.

Scotter, Emma L; Vance, Caroline; Nishimura, Agnes L; Lee, Youn-Bok; Chen, Han-Jou; Urwin, Hazel; Sardone, Valentina; Mitchell, Jacqueline C; Rogelj, Boris; Rubinsztein, David C; Shaw, Christopher E.

J Cell Sci ; 127(Pt 6): 1263-78, 2014 Mar 15.

Article in English | MEDLINE | ID: mdl-24424030

18.

The many faces of small nucleolar RNAs.

Bratkovic, Tomaz; Rogelj, Boris.

Biochim Biophys Acta ; 1839(6): 438-43, 2014 Jun.

Article in English | MEDLINE | ID: mdl-24735946

19.

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.

Vance, Caroline; Scotter, Emma L; Nishimura, Agnes L; Troakes, Claire; Mitchell, Jacqueline C; Kathe, Claudia; Urwin, Hazel; Manser, Catherine; Miller, Christopher C; Hortobágyi, Tibor; Dragunow, Mike; Rogelj, Boris; Shaw, Christopher E.

Hum Mol Genet ; 22(13): 2676-88, 2013 Jul 01.

Article in English | MEDLINE | ID: mdl-23474818

20.

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain.

Tollervey, James R; Wang, Zhen; Hortobágyi, Tibor; Witten, Joshua T; Zarnack, Kathi; Kayikci, Melis; Clark, Tyson A; Schweitzer, Anthony C; Rot, Gregor; Curk, Tomaz; Zupan, Blaz; Rogelj, Boris; Shaw, Christopher E; Ule, Jernej.

Genome Res ; 21(10): 1572-82, 2011 Oct.

Article in English | MEDLINE | ID: mdl-21846794

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Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition.

Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.

Cytoplasmic TDP-43 is involved in cell fate during stress recovery.

SFPQ regulates the accumulation of RNA foci and dipeptide repeat proteins from the expanded repeat mutation in C9orf72.

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.

Karyopherin abnormalities in neurodegenerative proteinopathies.

Functional diversity of small nucleolar RNAs.

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies.

Intracellular Responses Triggered by Cold Atmospheric Plasma and Plasma-Activated Media in Cancer Cells.

Exon-specific U1 snRNAs improve ELP1 exon 20 definition and rescue ELP1 protein expression in a familial dysautonomia mouse model.

Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

Nuclear trafficking in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import.

Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species.

The many faces of small nucleolar RNAs.

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.

Analysis of alternative splicing associated with aging and neurodegeneration in the human brain.