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Pediatr Neurol
; 146: 40-43, 2023 09.
Article
in English
| MEDLINE
| ID: mdl-37429225
ABSTRACT
Infantile botulism is an uncommon diagnosis and rarer still in the neonatal period. We describe three cases of neonatal-onset botulism that presented with symptoms typically (hypotonia, constipation, facial diplegia) or atypically seen in older infants (encephalopathy, seizures, and hypothermia). Our series shows a wider spectrum of clinical presentations in patients with neonatal-onset botulism. Our report also suggests that neonatal-onset botulism should be considered more broadly in the hypotonic infant, especially as the condition is treatable with intravenous botulinum-specific immune globulin.
Subject(s)
Botulism , Clostridium botulinum , Infant, Newborn, Diseases , Infant , Infant, Newborn , Humans , Aged , Botulism/diagnosis , Botulism/therapy , Antibodies , Immunoglobulins, Intravenous/therapeutic use
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